Effect of laser acupuncture on pain, range of motion, and function in patellofemoral pain syndrome: a randomised controlled trial by Nesma M. Allam, Hadeel Alsirhani, Maani Batel Alruwaili, Dalal Mabkhout Dosh, Huriyyah Mislat Alruwaili, Wessal Hisham Almazyad, Rokaia A. Toson, Doaa Ayoub Elimy, Doaa Ayoub Elimy, Mohamed El-Sherbiny, Ateya Megahed Ibrahim, Ateya Megahed Ibrahim, Hasnaa Ali Ebrahim, Nermine Nosseir, Mohamed A. Eladl, Zeinab A. Ali

“…BackgroundPatellofemoral pain syndrome (PFPS) is a knee disorder characterised by pain behind or surrounding the patella that predominantly affects adolescents.ObjectivesThis study aimed to evaluate the impact of laser acupuncture (LA) on pain, range of motion (ROM), and function in patients diagnosed with PFPS.Materials and methodsSixty participants, predominantly young women aged 18–25 years, were randomly distributed into two equal groups: Group A (LA group), which received laser acupuncture (LA) applied to six knee acupoints at 4 J for 80 s/point, in conjunction with an exercise programme; and Group B (Sham LA group), which received LA with the device deactivated, along with an exercise programme including stretching and strengthening exercises. …”
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Novel allelic variants of blaOXA-48-like carried on IncN2 and IncC2 plasmids isolated from clinical cases in Argentina: In vivo emergence of blaOXA-567 by Juan Manuel de Mendieta, Denise De Belder, Nathalie Tijet, Barbara Ghiglione, Roberto G. Melano, Melina Rapoport, Pablo Power, Adriana Di Bella, Estefanía Biondi, Fernando Pasterán, Alejandra Corso, Sonia A. Gomez

“…The aim of this study was to analyse the phenotypic profile and dissemination strategies of two novel OXA enzymes, blaOXA-438 and blaOXA-567, located in Escherichia coli M17224 and Klebsiella pneumoniae M21014, respectively, isolated from two paediatric patients. Methods: Minimum inhibitory concentration measurements were performed to determine the phenotypic profile of the clinical isolates, transconjugants and transformant cells. …”
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Effect of Sensory Integration Therapy on Attention Span and Gross Motor Skills in Children with Down Syndrome: A Quasi-experimental Study by Manshi Baberwal, Dimple Choudhry, Anjali, Anshu Kumari, Mallika Jhandai, Pankaj Bhardwaj, Ekta

“…Aim: To find out the effect of SIT on attention span and gross motor skills in children with DS. Materials and Methods: The present quasi-experimental study was conducted in various special schools in Rohtak, Haryana, India and at College of Physiotherapy, Pt. …”
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COVID‐19 and Healthcare Workers Burnt out: A Qualitative Study of Burnout Experiences of Healthcare workers in a Secondary Hospital in Ghana by Seth Christopher Yaw Appiah, Elvis Mwinsome Sobiesuo, Bernard Obeng, Elsie Asamoah, Comfort Badu Mantey, Peter Dwumah, Mary Sefa Boampong, Abena Afrakomah Boateng, Richard Ofori, Michael Nimoh, Josephine Boakyewaa Nyarko, Jonathan Mensah Dapaah

“…Design Descriptive phenomenological design. Methods The study adopted a qualitative approach, anchored on a descriptive phenomenological design to explore the dynamics of burnt‐out experienced by 12 healthcare staff at the Kwame Nkrumah University of Science and Technology (KNUST) hospital in Ghana during the COVID‐19 pandemic. …”
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Effects of different grain types on nutrient apparent digestibility, glycemic responses, and fecal VFA content in weaned foals by Xinxin Huang, Qian Li, Xuanyue Li, Chao Li, Jiahao Li, Linjiao He, Hongxin Jing, Fan Yang, Xiaobin Li

“…This study examines the impact of diets incorporating steam-flaked grains (corn, oats, and barley) on apparent nutrient digestibility, glycemic response, and fecal volatile fatty acid (VFA) composition in the weaned Kazakh foals. Methods Eighteen male Kazakh foals, weaned at 5 months, were randomly assigned to three groups (n = 6 per group) based on grain type: corn group (CG), oats group (OG), and barley group (BG). …”
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Socioeconomic disparities in the associations of age at last live birth with stroke and its subtypes among Chinese parous postmenopausal women: A prospective cohort study by Shiyi Shan, Weidi Sun, Jing Wu, Leying Hou, Zeyu Luo, Jiali Zhou, Jiayao Ying, Peige Song

“…Background: As a pivotal reproductive factor, age at last live birth (ALLB) plays a critical role in a woman's health trajectory, including the risk of cardiovascular diseases. Methods: In this prospective cohort study from the China Kadoorie Biobank (CKB), 148,456 parous postmenopausal women were included. …”
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Evaluation of the Effectiveness of the Socket Preservation Technique Using Allogeneic and Xenogeneic Materials—A Preliminary Study by Piotr Wróbel, Adam Piecuch, Michał Bąk, Paweł Krynicki, Jakub Adamczyk, Piotr Mojżesz, Agnieszka Kiełboń, Sylwia Wójcik, Martin Starosta, Won-Pyo Lee, Tadeusz Morawiec

“…Additionally, bone biopsies taken from the grafted sites underwent histological evaluation. Methods: This study enrolled 10 generally healthy patients, who were divided into two equal groups. …”
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Ultrasonography Assessment of Neck Anatomy for Prediction of Difficult Mask Ventilation in Obese Patients: A Prospective Observational Study by Ignatius Wong Hsun-Hong, Azarinah Izaham, Syarifah Noor Nazihah Sayed Masri, Muhammad Maaya, Siti Nidzwani Mohamad Mahdi, Khazrul Nizar Abd Kader, Maryam Budiman, Yazmin Yaacob

“…Our objective was to determine the correlation between the preoperative ultrasonography of anterior neck anatomy and difficult mask ventilation in different obesity classes. <b>Methods</b>: A prospective, observational study enrolled 90 adult obese patients undergoing general anesthesia from December 2020 to November 2021 (30 patients for each class of obesity). …”
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Comprehensive genome-wide analysis of the HMGR gene family of Asparagus taliensis and functional validation of AtaHMGR10 under different abiotic stresses by Liangqin Zeng, Liangqin Zeng, Sylvia E. Brown, He Wu, Wenhua Dongchen, Yunbin Li, Chun Lin, Chun Lin, Zhengjie Liu, Zhengjie Liu, Zhengjie Liu, Zichao Mao, Zichao Mao, Zichao Mao

“…This study investigates the stress response mechanisms of the HMGR gene family in A. taliensis under abiotic stress conditions.MethodsA comprehensive genome-wide analysis of the HMGR gene family in A. taliensis was conducted. …”
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The WHEAT pilot trial—WithHolding Enteral feeds Around packed red cell Transfusion to prevent necrotising enterocolitis in preterm neonates: a multicentre, electronic patient recor... by Neena Modi, Jon Dorling, Chris Gale, Tjeerd Van Staa, Louise Linsell, Ursula Bowler, Ed Juszczak, Mark A Turner, Sena Jawad, Amanda Forster, Andy King, Jenny McLeish, Helen Robberts, Kayleigh Stanbury

“…The use of a simplified opt-out consent model and embedding trial processes within existing electronic patient record (EPR) systems provide opportunities to increase trial efficiency and recruitment.Methods and analysis We will undertake a randomised, controlled, multicentre, unblinded, pilot trial comparing two care pathways: continuing milk feeds (before, during and after red cell transfusions) and withholding milk feeds (for 4 hours before, during and for 4 hours after red cell transfusions), with infants randomly assigned with equal probability. …”
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The Manitoba Personalized Lifestyle Research (TMPLR) study protocol: a multicentre bidirectional observational cohort study with administrative health record linkage investigating... by Navdeep Tangri, Dylan Mackay, Rebecca C Mollard, Matthew Granger, Sharon Bruce, Heather Blewett, Jared Carlberg, Todd Duhamel, Peter Eck, Patrick Faucher, Naomi C Hamm, Ehsan Khafipour, Diana McMillan, Semone Myrie, Amir Ravandi, Meghan Azad, Peter JH Jones

“…The objective of The Manitoba Personalized Lifestyle Research study is to understand how these lifestyle factors interact with each other and with other factors, such as an individual’s genetics and gut microbiome, to influence health.Methods An observational study of adults, with extensive phenotyping by objective health and lifestyle assessments, and retrospective assessment of early life experiences, with retrospective and prospective utilisation of secondary data from administrative health records.Study population A planned non-random convenience sample of 840 Manitobans aged 30–46 recruited from the general population, stratified by sex (equal men and women), body mass index (BMI; 60% of participants with a BMI&gt;25 kg/m2) and geography (25% from rural areas). …”
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Phase II study of concomitant radiotherapy with atezolizumab in oligometastatic soft tissue sarcomas: STEREOSARC trial protocol by Nicolas Penel, Dominique Vaur, Juliette Thariat, Alexandre Escande, Jennifer le Guevelou, Colin Debaigt, Esma Saada-Bouzid, Julien Viotti, Nazim Khalladi, David Thibouw, Marie Pierre Sunyach, Laurence Moureau-Zabotto, Mohamed Benchalal, Ovidiu Veresezan, Anne Ducassou, Cecile le Pechoux, Maria Jolnerovski, Celine Bazille, Raphael Serre, Christine Lovera

“…In order to shift the balance towards antitumour immunity by multisite irradiation, radiation could be combined with inhibitors of the immunosuppressive pathways.Methods and analysis STEREOSARC is a prospective, multicentric, randomised phase II, designed to evaluate the efficacy of SBRT associated with immunotherapy versus SBRT only. …”
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Obstacles for self-management practices among diabetes patients: A facility-based study from Coastal South India. [version 3; peer review: 2 approved] by Murali Mohan R, Rekha T, Balanarayana Suma, Nithin Kumar, Kausthubh Hegde, Bhaskaran Unnikrishnan, Prasanna Mithra, Ramesh Holla, Aysha Roushida Sahama M, Aadithya M Rao, Patil Nikitha

“…Background The management of diabetes mellitus (DM) extends beyond clinical care, with self-care being equally important to achieve optimal treatment outcomes and prevent complications. …”
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REMAP Periop: a randomised, embedded, multifactorial adaptive platform trial protocol for perioperative medicine to determine the optimal enhanced recovery pathway components in co... by Brian Williams, Jennifer Holder-Murray, Kathirvel Subramaniam, Kert Viele, Oscar C Marroquin, Scott Berry, Aman Mahajan, Luca La Colla, Charles Luke, Alison R Althans, Stephen A Esper, Joshua Knight, Joseph Derenzo, Ryan Ball, Shawn Beaman, Nicholas Schott, Elizabeth Lorenzi, Lindsay R Berry, Miranda Masters, Katie A Meister, Todd Wilkinson, William Garrard

“…Patients enrolled in the trial will be randomised to arms within both domains, with the possibility of adding additional domains in the future.Methods and analysis In the PONV domain, patients are randomised to optimal versus supraoptimal prophylactic regimens. …”
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The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss by Jessica Murphy, Jessica Murphy, Jessica Murphy, José A. Morais, José A. Morais, Michael A. Tsoukas, Alexandra B. Cooke, Stella S. Daskalopoulou, Stella S. Daskalopoulou, Stella S. Daskalopoulou, Sylvia Santosa, Sylvia Santosa, Sylvia Santosa

“…Weight loss can modify adipose tissue immune cell composition, but whether these changes differ by obesity onset remains unknown.MethodsWe compared abdominal and femoral subcutaneous adipose tissue (SAT) immune cell percentages between people with CO and AO before and after moderate (~10%) weight loss. …”
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Low-concentration atropine (0.01%) on quantitative contrast sensitivity function in Chinese children with myopia by Yu-Hao Ye, Yi-Yong Xian, Fang Liu, Zhong-Lin Lyu, Xing-Tao Zhou, Jing Zhao

“…AIM: To investigate the effect of 0.01% low-concentration atropine (LA) on quantitative contrast sensitivity function (qCSF) in children with myopia. METHODS: This paired case-control study included 90 eyes of 58 children who were sex-, age-, and refraction-matched and equally divided into two groups: the 0.01% LA group had undergone 6mo use of daily 0.01% atropine and control group was naïve to LA. …”
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Generation of superoxide anion-radical in leaves of soft wheat (Triticum aestivum L.) under the action of a high-intensity pulsed magnetic field by Oleg V. Blednykh, Natalia A. Rodenko, Vladimir A. Glushchenkov, Yulia V. Degteva

“…The purpose of this study is to study the effect of high-intensity pulsed magnetic fields with induction from 0.1 Tl on the generation of superoxide anion-radicals in leaves of soft wheat Triticum avestivum L. as a response to this action. Materials and methods. The objects of the study were nine-day-old green and etiolated wheat sprouts of soft wheat Triticum avestivum L., grown in distilled water. …”
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Low sensitivity of the fourth‐generation antigen/antibody HIV rapid diagnostic test Determine™ HIV Early Detect for detection of acute HIV infection at the point of care in rural E... by Iza Ciglenecki, Nombuso Ntshalintshali, Esther Mukooza, Skinner Lekelem, Mpumelelo Mavimbela, Sindisiwe Dlamini, Lenhle Dube, Nomvuyo Mabuza, Melat Haile, Tom Ellman, Antonio Flores, Olivia Keiser, Sindy Matse, Roberto de laTour, Alexandra Calmy, Bernhard Kerschberger

“…We nested a diagnostic accuracy study within a larger study of the burden of sexually transmitted infections in rural Eswatini. Methods Adults were enrolled at six routine HIV testing sites (HTS) in the Shiselweni region between June 2022 and April 2023. …”
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A comparison of applicant and accepted student characteristics to research training programs with implications for recruitment and selection strategy by Young-Hee Cho, Young-Hee Cho, Chi-Ah Chun, Chi-Ah Chun, Hector Ramos, Paul Buonora, Paul Buonora, Paul Buonora, Vasanthy Narayanaswami, Vasanthy Narayanaswami, Kim-Phuong L. Vu, Kim-Phuong L. Vu

“…Its second aim was to investigate whether applicants who were accepted to the programs using a holistic selection process differed in academic discipline, demographics, and psychosocial characteristics from applicants who were not accepted.MethodsInformation on students’ majors, race/ethnicity, and gender was obtained from the university records or applications submitted by students. …”
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Whole-body and site specific [18F]FDG uptake patterns on PET/CT have limited value in differentiating between polymyalgia rheumatica and other inflammatory diseases: two cohorts of... by Andreas Wiggers Nielsen, Gijs D. van Praagh, Kornelis S. M. van der Geest, Ib Tønder Hansen, Berit Dalsgaard Nielsen, Søren Geill Kjær, Jesper Blegvad-Nissen, Kate Rewers, Christian Møller Sørensen, Elisabeth Brouwer, Ellen-Margrethe Hauge, Lars Christian Gormsen, Riemer H. J. A. Slart, Kresten Krarup Keller

“…Therefore, this study aimed to investigate both the overall whole-body [18F]FDG-uptake patterns and the specific uptake patterns at individual sites in patients suspected of having PMR. Methods Two distinct cohorts of patients with suspected PMR from Denmark and the Netherlands were prospectively included, encompassing 66/27 and 36/21 PMR/non-PMR patients, respectively. …”
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