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  1. 9721

    Burden of Carbon Monoxide Poisoning in Asian Countries From 1990 to 2021 and Its Projection Until 2030: An Analysis of the Global Burden of Disease Study 2021 by Xie J, Wu C, Zhao Z, Cao Z, Jin X

    Published 2025-04-01
    “…This study seeks to assess the burden of CO poisoning in Asia from 1990 to 2021 utilizing data from the Global Burden of Disease Study (GBD) 2021.Methods: Data on the burden of CO poisoning across 49 Asian countries were extracted from GBD 2021. …”
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  2. 9722

    Efficacy of a Web-Based Stress Management Intervention for Beginning Teachers on Reducing Stress and Mechanisms of Change: Randomized Controlled Trial by Hanna Heckendorf, Dirk Lehr

    Published 2025-06-01
    “…In addition, this study was the first to explore problem-solving ability and emotion regulation skills as potential mechanisms of change within an iSMI grounded in transactional stress theory. MethodsParticipants were 200 highly stressed beginning teachers (Perceived Stress Scale score of >21) undergoing German teacher induction randomized to either an intervention group (IG) with guidance or a waitlist control group. …”
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  3. 9723

    Determinants of Healthcare Professionals’ Knowledge on Age-Related Macular Degeneration Risk Factors in Ethiopia by Alemu DS, Munaw MB, Bekele MM, Asmare Kindie C, Ayele FA, Limenih MA

    Published 2025-06-01
    “…Destaye Shiferaw Alemu,1,* Minychil Bantihun Munaw,2 Matiyas Mamo Bekele,2 Chalie Asmare Kindie,3 Fisseha Admassu Ayele,3 Miteku Andualem Limenih1,* 1Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Amhara National Regional State, Ethiopia; 2Department of Optometry, School of Medicine, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Amhara National Regional State, Ethiopia; 3Department of Ophthalmology, School of Medicine, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Amhara National Regional State, Ethiopia*These authors contributed equally to this workCorrespondence: Destaye Shiferaw Alemu, Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, P.O.Box: 196, Gondar, Ethiopia, Tel +251938316951, Email destayest@gmail.comPurpose: The aim of this study was to assess knowledge of healthcare professionals on risk factors of age-related macular degeneration and to identify factors that affect their level of knowledge.Patients and Methods: A cross-sectional study design was employed to collect data from 607 healthcare professionals in Gondar City from August 1 to 30, 2024. …”
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  4. 9724

    Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial by Shi S, Wu J, Wu Y, Han X, Dai H, Chen X, Sun Z, Wang F

    Published 2025-02-01
    “…Shuqi Shi,1,2,* Jimin Wu,1,* Yini Wu,1 Xin Han,1 Hong Dai,1 Xuedong Chen,3 Zhangnan Sun,4 Faxing Wang1,2 1Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 2Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 4Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email wfx2023@wmu.edu.cn Zhangnan Sun, Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email 28703077@hebmu.edu.cnObjective: This study compares postoperative recovery quality between Ciprofol and Propofol, providing a reference for the clinical application of anesthetics.Methods: We randomized 112 patients undergoing ureteroscopic surgery into two groups: the Ciprofol group (Group C), with an induction dose of 0.4 mg/kg and a maintenance dose of 0.8– 1.5 mg/(kg·h), and the Propofol group (Group P), with an induction dose of 2 mg/kg and a maintenance dose of 4– 10 mg/(kg·h). …”
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  5. 9725

    TRANSUMBILICAL LAPAROSCOPIC CHOLECYSTECTOMY VERSUS STANDARD 4-PORT LAPAROSCOPIC CHOLECYSTECTOMY – RESULTS FROM PROSPECTIVE RANDOMIZED TRIAL AND 7 YEARS OF FOLLOW-UP by G. Ganchev, A. Saroglu, A. Julianov

    Published 2020-12-01
    “…The aim of this study is to compare the results of our own modification of transumbilical cholecystectomy versus standard 4-port cholecystectomy in patients with uncomplicated gallstone disease. METHODS: 80 patients (14 male, 66 female) at a mean age of 35±2,5 years (range 18-80) were randomly assigned to either standard 4-port cholecystectomy (n=40) or transumbilical cholecystectomy (n=40). …”
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  6. 9726

    The Interactive Care Coordination and Navigation mHealth Intervention for People Experiencing Homelessness: Cost Analysis, Exploratory Financial Cost-Benefit Analysis, and Budget I... by Hannah P McCullough, Leticia R Moczygemba, Anton L V Avanceña, James O Baffoe

    Published 2025-03-01
    “…ObjectiveThis study aimed to conduct a three-part economic evaluation of iCAN, including a (1) cost analysis, (2) exploratory financial cost-benefit analysis, and (3) budget impact analysis (BIA). MethodsWe collected cost and expenditure data from a randomized controlled trial of iCAN to conduct a cost analysis and exploratory financial cost-benefit analysis. …”
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  7. 9727

    Electroacupuncture at ST36 Treatment Suppresses the Microglial Pyroptosis Through Activating α7nAChR in a Rat Model of Asphyxial Cardiac Arrest by Qin Y, Ma G, Xiao X, Liu Y, Zhao Z, Zhao F, Guo F, Wang S, Sun X, Gao C

    Published 2025-07-01
    “…Nevertheless, the neuroprotective effect of electroacupuncture at ST36 (EA-ST36) in CA-induced global cerebral ischemia injury and the underlying mechanisms remains unclear.Methods: Using a rat model of Asphyxial Cardiac Arrest, the neuroprotective effects of EA-ST36 were evaluated. …”
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  8. 9728

    Comparison of STAR and GOLD in Assessing Disease Severity Among High-Risk and COPD Patients: Evidence from Enjoying Breathing Program in China by Huang K, Tang X, Chu X, Niu H, Li W, Zheng Z, Peng Y, Lei J, Li Y, Li B, Yang T, Wang C

    Published 2024-12-01
    “…However, the effectiveness of STAR and GOLD staging in distinguishing disease severity in high-risk and COPD patients remained unclear.Methods: Based on Enjoying Breathing Program data through June 2023, a total of 7.924 high-risk and COPD patients were included. …”
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  9. 9729

    Genetic Alterations in HER2-Positive and Equivocal Breast Cancer by Immunohistochemistry by Tsai YF, Hsu CY, Chiu YN, Huang CC, Chou SH, Lin YS, Chao TC, Liu CY, Chiu JH, Tseng LM

    Published 2025-03-01
    “…Yi-Fang Tsai,1– 3 Chih-Yi Hsu,3,4 Yun-Ning Chiu,1,5 Chi-Cheng Huang,1,6 Shih-Hsiang Chou,1 Yen-Shu Lin,1– 3 Ta-Chung Chao,1,3,7 Chun-Yu Liu,1,3,8,* Jen-Hwey Chiu,1,2,9,* Ling-Ming Tseng1– 3 1Comprehensive Breast Health Center, Department of Surgery, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 2Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 3Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112201, Taiwan; 4Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 5Division of General Surgery, Department of Surgery, Shaung Ho Hospital, Taipei Medical University, Taipei City, 23561, Taiwan; 6Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, 100233, Taiwan; 7Division of Cancer Prevention, Department of Oncology, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 8Division of Medical Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, 112201, Taiwan; 9Division of General Surgery, Department of Surgery, Cheng-Hsin General Hospital, Taipei, 112401, Taiwan*These authors contributed equally to this workCorrespondence: Jen-Hwey Chiu, Comprehensive Breast Health Center, Department of Surgery, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Road, Taipei City, 112201, Taiwan, Tel +886-2-55681176, Fax +886-2-55681185, Email chiujh10@nycu.edu.twPurpose: We aimed to identify genetic alterations in groups with different HER2 immunohistochemical (IHC) scores.Patients and Methods: A total of 120 patients with HER2-positive breast cancers, including 89 cases with IHC 3+ tumors and 31 cases with IHC 2+ and positive for in situ hybridization (ISH) were enrolled. …”
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  10. 9730

    Comparative Evaluation of Efficacy and Complications Between Biportal Endoscopic Lumbar Interbody Fusion and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar De... by Hu Q, Xiao K, Nan JN, Jhang SW, Chen CM, Lin GX

    Published 2025-04-01
    “…Qianqin Hu,1 Keyi Xiao,2 Jin-Niang Nan,3 Shang-Wun Jhang,4 Chien-Min Chen,4– 6,* Guang-Xun Lin7,* 1First Department of Orthopedics, Jiangxi Province Hospital of Integrated Chinese and Western Medicine, Nanchang, Jiangxi, People’s Republic of China; 2The School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, People’s Republic of China; 3Department of Clinical Medicine, Nanchang Medical College, Nanchang, Jiangxi, People’s Republic of China; 4Division of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan; 5Department of Leisure Industry Management, National Chin-Yi University of Technology, Taichung, Taiwan; 6Department of Biomedical Sciences National Chung Cheng University, Chiayi, Taiwan; 7Department of Orthopedics, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chien-Min Chen, Email 96015@cch.org.tw Guang-Xun Lin, Email linguangxun@hotmail.comObjective: To effectuate a comprehensive juxtaposition of the clinical implications, incidence of complications, and successful fusion rates observed in the context of biportal endoscopic lumbar interbody fusion (BE-LIF) and minimally invasive transforaminal lumbar interbody fusion (MI-TLIF).Methods: The present research initiative involved an exhaustive exploration of pertinent scholarly literature in renowned databases, which lasted until April 2023. …”
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  11. 9731

    Mitochondria-Targeting Virus-Like Gold Nanoparticles Enhance Chemophototherapeutic Efficacy Against Pancreatic Cancer in a Xenograft Mouse Model by Meng Y, Chen C, Lin R, Zheng L, Fan Y, Zhang M, Zhang Z, Shi H, Zheng X, Chen J, Chen D, Teng T, Chen B

    Published 2024-12-01
    “…Gold nanoparticles (AuNPs) have emerged as promising nanocarriers to overcome the extracellular matrix barrier; however, their limited targeting precision, poor delivery efficiency, and insufficient photothermal conversion present challenges.Methods: We developed triphenyl phosphonium-functionalized high-branch gold nanoparticles, denoted as Dox@TPAu, to enhance drug delivery and targeting capabilities. …”
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  12. 9732

    Sarcopenia, Depressive Symptoms, and Fall Risk: Insights from a National Cohort Study in the Chinese Population by Zhang X, Ye D, Dou Q, Xie F, Zeng R, Zhu K, Zhu W, Zhu A, Chen L, Wu Y, Fan T, Peng P, Huang Y, Xiao S, Bian J, Shi M, Wang J, Zhang W

    Published 2025-02-01
    “…This study aims to assess the combined influence of sarcopenia and depressive symptoms on the occurrence of falls in the Chinese population.Methods: The analysis included 8,405 participants from the China Health and Retirement Longitudinal Study (CHARLS), conducted from 2011 to 2015. …”
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  13. 9733

    VOPP1 as a Novel Susceptibility Gene in Rheumatoid Arthritis: Insights Into Its Mechanisms From Mendelian Randomization and Experimental Validation by Wu W, Cai H, Nan Y, Tang J, Wang Y

    Published 2025-08-01
    “…In this paper, we identified new susceptibility genes in RA and investigated their underlying mechanisms using integrated Mendelian randomization (MR) analysis.Methods: Two-sample MR analyses were used to determine the causative links among eQTLs, metabolites, and RA risk. …”
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  14. 9734

    Effects of pelvic obliquity and limb position on radiographic leg length discrepancy measurement: a Sawbones model by Mohammed Nazmy Hamad, Isaac Livshetz, Anshum Sood, Michael Patetta, Mark H. Gonzalez, Farid A. Amirouche

    Published 2022-01-01
    “…In the present study, we sought to characterize the effects of varying degrees of lateral pelvic obliquity (PO) and mediolateral limb movement in the coronal plane on LLD measurement error (ME). Methods A 3‐D sawbones model of the pelvis with bilateral femurs of equal‐length was assembled. …”
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  15. 9735

    Correlation Between Blood Pressure Variability and Serum Vascular Endothelial Growth Factor Concentration in Patients with Type I Cerebral Small Vessel Disease by Yang H, Wang Q, Li M, Yu J, Li H, Zhang S, Qian H

    Published 2025-04-01
    “…Hua Yang,1,2,* Qianyao Wang,3,* Min Li,1,* Jin Yu,1 Hua Li,1 Shufeng Zhang,1 Hairong Qian3 1Department of Neurology, The First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China; 2Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education; Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 3Navy Clinical College, The Fifth School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hairong Qian, Navy Clinical College, The Fifth School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, 230032, People’s Republic of China, Email qianhairong_cn@163.comObjective: To investigate the relationship between blood pressure variability (BPV) and serum vascular endothelial growth factor (VEGF) levels in patients with type I cerebral small vessel disease (CSVD).Methods: 144 Patients admitted to the Neurology Department of our Hospital between December 2021 and December 2022 were included and categorized into 5 groups according to CSVD burden, which was evaluated based on MRI findings. …”
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  16. 9736

    Prognostic Role of SETDB2 in Clear Cell Renal Cell Carcinoma: Linking Immune Infiltration, Cuproptosis, and Tumor Suppression by Lu SH, Lui K, Qian Y, Zhou WY, Mu YY, Zhang W

    Published 2025-03-01
    “…SET domain bifurcated histone lysine methyltransferase 2 (SETDB2) belongs to the Su(var)3– 9 subfamily of methyltransferases and has been linked to various forms of cancer, but the role it plays in ccRCC remains to be fully established.Methods: Data on SETDB2 expression were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. …”
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  17. 9737

    Facemask-wearing behavior to prevent COVID-19 and associated factors among public and private bank workers in Ethiopia. by Seada Hassen, Metadel Adane

    Published 2021-01-01
    “…To address this gap and to consider intervention measures that encourage the wearing of facemasks, this study was conducted to identify behaviors of facemask wearing and associated factors among bank workers in Dessie City, Ethiopia.<h4>Materials and methods</h4>An institution-based cross-sectional study was conducted among 413 bank workers who were selected using a simple random sampling technique from January 1st to 30th, 2021 in Dessie City, Ethiopia. …”
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  18. 9738

    Rates of Multidrug-Resistant Gram-Negative Bacterial Infections in Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study at a Lebanese Tertiary Medica... by Zakhour R, Khafaja S, Korman R, Boutros CF, El Zein Z, Chmaisse A, Haj M, Haddara A, El-Houry Z, Jbahi M, Chamseddine S, Bou Karroum S, Al Oweini D, Youssef YS, Youssef N, Nasser M, Fayad D, Abi Farraj F, El Nakib C, Isaac I, Lteif M, Araj GF, Dbaibo GS

    Published 2025-01-01
    “…The objectives of this study were to describe the epidemiology, potential contributing factors, and antimicrobial resistance patterns associated with infections caused by MDR Gram-negative bacteria (GNB) in non-immunocompromised children and adolescents.Methods: This was a retrospective observational study conducted at the American University of Beirut Medical Center (AUBMC) from 2009 to 2017. …”
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  19. 9739

    The Correlation Between Airborne Pollen and Sensitization in Children with Respiratory Allergic Diseases: A Cross-Sectional Study by Xu L, Dai Y, Luo W, Jiang W, Tan Q, Lu Y, Huang Z, Gu W, Li P, Wang P, Huang L, Sun H, Hao C, Sun B

    Published 2024-12-01
    “…Lina Xu,1,&ast; Yinfang Dai,1,&ast; Wenting Luo,2,&ast; Wujun Jiang,1 Qianlei Tan,1 Yanhong Lu,1 Zhifeng Huang,2 Wenjing Gu,1 Pengyun Li,1 Pengli Wang,1 Li Huang,1 Huiquan Sun,1 Chuangli Hao,1 Baoqing Sun2 1Department of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 2Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Chuangli Hao, Department of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, 215003, People’s Republic of China, Email hcl_md@sina.com Baoqing Sun, Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People’s Republic of China, Email sunbaoqing@vip.163.comBackground: Pollen is a significant contributor to respiratory allergies worldwide, underscoring the importance of understanding its association with childhood sensitization to enhance clinical management.Objective: This study focuses on investigating the prevalence of various airborne pollens and their correlation with clinical characteristics of childhood respiratory allergic diseases in southeastern China.Methods: From November 2020 to October 2021, this research employed Durham monitoring samplers to collect airborne pollen. …”
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  20. 9740

    Prevalence of Site-Specific Mycoplasma genitalium Infection and Macrolide and Fluoroquinolone-Associated Mutations in Men Who Have Sex with Men in Shenzhen, China by Leng X, Zhu R, Ao X, Zhou Y, Zhang K, Hu T, Wu J, Chen Z, Huang L, Huang N, Li X, Ahmed Alnour R, Xue Z, Zhang X, Liu H, Axirejiang T, Ke W, Zou H

    Published 2025-01-01
    “…We aimed to assess site-specific MG infection and its correlates and macrolide and fluoroquinolones mutations among men who have sex with men (MSM) in Shenzhen, China.Methods: Samples were obtained from different anatomic sites of MSM based on their sexual behavior. …”
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