Translation and validation of the German version of the Pet-Related Stress Scale by André Hajek, Ariana Neumann, Larissa Zwar, Razak M. Gyasi, Razak M. Gyasi, Dong Keon Yon, Supa Pengpid, Supa Pengpid, Supa Pengpid, Karl Peltzer, Karl Peltzer, Karl Peltzer, Rosalie Corona, Shelby Elaine McDonald, Hans-Helmut König

“…Moreover, reference values were determined.MethodsData for validation were gathered from a quota-based online sample of Germany’s adult population aged 18 to 74 years, with n = 3,270 representing the demographic distribution of Germany in terms of sex, age, and federal states. …”
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Effects of carvacrol on growth performance, carcass traits, serum biochemistry, and intestinal gut microflora of broiler chickens by Imen Belhadj Slimen, Imen Belhadj Slimen, Mohamadi Val Boa, Sana Lengliz, Sana Lengliz, Bochra Bejaoui, Bochra Bejaoui, Hafaoua Samti, Mohamed Salah Abbassi, Naceur M’Hamdi, Ludovic Chaveriat, Patrick Martin, Manef Abderrabba, Taha Najar

“…Essential oils and their chemotypes have been recognized for their antimicrobial properties and emerged as promising molecules that may be used for sustainable poultry production and respond to the challenges posed by the One Health concept.MethodsThis trial was conducted to evaluate the effects of carvacrol at two levels (0 and 20 mg/Kg of diet) on growth performances, carcass traits, serum biochemicals, and intestinal gut microflora counts in broiler chickens. …”
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Evaluating the Opioid-Related Adverse Events of Oliceridine Versus Conventional Opioids in Patient-Controlled Analgesia After Thoracoscopic Lung Resection: A Retrospective Cohort S... by Huang C, Liu B, Xie S, Zhang Y, Liu K, Qiu Y, Wu J

“…This study aims to elucidate the differences in ORADE rates between oliceridine and conventional opioids in PCIA.Methods: We conducted a population-based retrospective cohort study at Shanghai Chest Hospital, analyzing linked healthcare data. …”
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Analysis of Acupoint Selection and Combinations in Acupuncture Treatment of Trigeminal Neuralgia: A Protocol for Data Mining by He Y, Li L, Zhou M, Xu Y, Tang J, Wu Y, Liu M, Xing B, Li X, Wang X

“…This lack of clarity obstructs the standardization of acupuncture treatment, emphasizing the need for further research.Objective: Our purpose is to conduct the first thorough data mining analysis to identify the most effective acupoint selection and combinations for treating trigeminal neuralgia from published clinical trials.Methods: We will search 8 electronic bibliographic databases (PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang Database, Chinese Biomedical Literature Database and Chongqing VIP Database) from inception to May 2025. …”
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Molecular and Transmission Characteristics of Mycobacterium Tuberculosis Strains Among College Students in Beijing, China by Cao X, Li X, Song Z, He P, Zhang R, Teng C, Sun Q, Wang X, Zhao B, Zhang Z, Zhao Y

“…The aim of this study is to analyze the genetic diversity and drug resistance of Mycobacterium tuberculosis strains in college students with tuberculosis in Beijing, revealing the lineage structure and transmission patterns specific to this group.Methods: This study used the hospital’s electronic management system to screen for tuberculosis among college students in Changping District, Beijing, from January 2004 to December 2023. …”
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Synergistic Effect of the CHA2DS2-VASc Score and Left Atrial Epicardial Adipose Tissue Volume on Predicting Atrial Fibrillation Recurrence After Ablation by Sang C, Gu R, Xia T, Shao Y, Zhu Y, Chen F, Sun L, Gu X, Zhang C

“…This study aims to evaluate the predictive potential of combining CHA2DS2-VASc score and LA-EAT volume in predicting recurrence in patients with AF who undergo ablation.Methods: The study encompassed a cohort of 507 patients who underwent ablation for AF finally. …”
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Patient Factors Associated With the Use of Online Portal Health Information in the Postpandemic Era: Cross-Sectional Analysis of a National Survey by Ishana Maini, Kevin Gilotra, Gelareh Sadigh

“…ObjectiveThe purpose of this study was to assess the prevalence of portal use and factors associated with patients’ portal access after the COVID-19 pandemic. MethodsThis study used data from the 2022 National Cancer Institute’s Health Information National Trends Survey (HINTS 6). …”
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Association Between Low Triglyceride-Glucose Index and Mortality in Acute Decompensated Heart Failure Patients Without Diabetes by Zhang Q, Xu Y, Sun S, Ding X, Wang G, Jiang S, Zheng J, Gao P, Lin J, Wu Y

“…This study aimed to investigate the association between a low TyG index and 1-year mortality in ADHF patients without diabetes.Methods: A total of 652 hospitalized patients with ADHF without diabetes from January, 2020 to May, 2023 were included in this retrospective study. …”
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Advanced Practice Respiratory Therapy in the State of California: A Cross-Sectional Needs Assessment Study by Alismail A, Xu Y, Craddock K, Lopez D, Terry M, Tan L

“…Abdullah Alismail,1– 3,* Yiqing Xu,1,* Krystal Craddock,4 David Lopez,1 Michael Terry,1,5 Laren Tan1,2 1Department of Cardiopulmonary Sciences, School of Allied Health Professions, Loma Linda University Health, Loma Linda, CA, USA; 2Department of Medicine, Loma Linda University Health, Loma Linda, CA, USA; 3Department of Cardiopulmonary Sciences, College of Health Science, Rush University, Chicago, IL, USA; 4Department of Respiratory Care, University of California Davis Medical Center, Sacramento, CA, USA; 5Department of Respiratory Care, Loma Linda University Medicine Center, Loma Linda, CA, USA*These authors contributed equally to this workCorrespondence: Abdullah Alismail, Department of Cardiopulmonary Sciences, Loma Linda University, Loma Linda, CA, USA, Email aalismail@llu.eduIntroduction: As the respiratory therapy (RT) profession in the United States discusses the establishment of the Advanced Practice in Respiratory Therapy (APRT) profession, the purpose of this study was to investigate the perception of the respiratory therapy community in the state of California (CA) on the need to start the APRT profession within the state.Methods: This was a descriptive pilot cross-sectional anonymous study that was approved by the institutional review board at Loma Linda University. …”
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Location of Al and Si atoms in substituted boron carbide by V. V. Garbuz, V. A. Sydorenchuk, V. B. Muratov, L. N. Kuzmenko, A. A. Vasiliev, P. V. Mazur, M. V. Karpets, T. V. Khomko, T. A. Silinska, T. N. Terentyeva, L. O. Romanova

“…Passage of the substitution reaction in boron carbide powders with Al and Si vapors in vacuum was found. Certification methods: chemical analysis, full-profile XPA (Powder Cell for Windows. …”
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PEG-Polymeric Nanocarriers Alleviate the Immunosuppressive Effects of Free 4-Thiazolidinone-Based Chemotherapeutics on T Lymphocyte Function and Cytokine Production by Tulinska J, Kobylinska L, Lehotska Mikusova M, Babincova J, Mitina N, Rollerova E, Liskova A, Madrova N, Alacova R, Zaichenko A, Lesyk R, Horvathova M, Szabova M, Lukan N, Vari S

“…Jana Tulinska,1,* Lesya Kobylinska,2,* Miroslava Lehotska Mikusova,1 Julia Babincova,3 Natalia Mitina,4 Eva Rollerova,1 Aurelia Liskova,1 Nikola Madrova,1 Radka Alacova,3 Alexander Zaichenko,4 Roman Lesyk,5 Mira Horvathova,1 Michaela Szabova,1 Norbert Lukan,1 Sandor Vari6 1Faculty of Medicine, Slovak Medical University, Bratislava, Slovakia; 2Department of Biochemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine; 3Faculty of Public Health, Slovak Medical University, Bratislava, Slovakia; 4Department of Organic Chemistry, Lviv Polytechnic National University, Lviv, Ukraine; 5Department of Pharmaceutical, Organic and BioOrganic Chemistry Danylo Halytsky Lviv National Medical University, Lviv, Ukraine; 6International Research and Innovation in Medicine Program, Cedars - Sinai Medical Center, Los Angeles, CA, USA*These authors contributed equally to this workCorrespondence: Lesya Kobylinska, Department of Biochemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine, Email KobylinskaLesya@meduniv.lviv.ua Norbert Lukan, Faculty of Medicine, Slovak Medical University, Bratislava, Slovakia, Email norbert.lukan@szu.skPurpose: Our study aimed to assess the effects of anticancer 4-thiazolidinone-based free water-insoluble therapeutics Les-3288 and Les-3833 and their waterborne complexes with branched PEG-containing polymeric carriers (A24-PEG550 and A24-PEG750) on immune response.Methods: Human peripheral blood was used to study in vitro lymphocyte proliferative function, leukocyte phagocytic activity and respiratory burst, and cytokine production.Results: The binding of the polymer to the anticancer drug Les-3288, which is intended to mitigate the immunosuppressive effects of the free drug on the proliferative activity of T lymphocytes and T-dependent B cells, demonstrated comparable efficacy for both A24-PEG750 and A24-PEG550 nanocarriers. …”
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Etlingera Elatior Inflorescence Extract Mitigates Acute Gastric Ulcers by Suppressing the Expression of Inducible Nitric Oxide Synthase in Ethanol-Induced Wistar Rats by Prayoga DK, Aulifa DL, Budiman A, Levita J, Jiranusornkul S

“…However, such a study on the downregulation of the iNOS expression is lacking.Purpose: To confirm the gastro-protective and anti-ulcer effects of the E. elatior inflorescence (EEIE) extract via downregulation of iNOS expression in ethanol-induced gastric ulcer rats.Methods: The fresh inflorescence petals were collected from West Java, Indonesia, and were extracted using 70% ethanol. …”
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Long-Term Outcomes of a Health Information System-Based Feedback Intervention Study of Antimicrobial Prescriptions in Primary Care Institutions: Follow-Up of a Randomized Cross-Ove... by Yan Y, Yang J, Lu Y, Cui Z, Chang Y

“…Yuxing Yan,1,* Junli Yang,1,* Yun Lu,2 Zhezhe Cui,3 Yue Chang1,4 1School of Medicine and Health Management, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China; 2School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China; 3Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, Guangxi Province, People’s Republic of China; 4Center of Medicine Economics and Management Research, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yue Chang, School of Medicine and Health Management, Guizhou Medical University, 6 Ankang Avenue, GUI ‘An New District, Guiyang, Guizhou Province, People’s Republic of China, Tel/Fax +86-0851-88308118, Email 4567401@qq.com Zhezhe Cui, Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, 18 Jinzhou Road, Nanning, Guangxi Province, People’s Republic of China, Tel/Fax +86-0771-2518785, Email czz6997@163.comPurpose: To evaluate the long-term impacts of the feedback intervention on controlling inappropriate use of antimicrobial prescriptions in primary care institutions in China, as a continuation of the previous feedback intervention trial.Methods: After the intervention ended, we conducted a 12-month follow-up study. …”
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Time-Varying Effects of Glucocorticoid Treatment in Critically III Patients with Severe Fever with Thrombocytopenia Syndrome: An Inverse Probability of Treatment Weighting Analysis by Xia P, Liu Y, Wang J, Li H, Zhai Y, Wang B, Tong H, Ge W, Jiang C

“…Peng Xia,1,2,* Yun Liu,3,* Jun Wang,3,* Haopeng Li,4 Yu Zhai,3 Baoyan Wang,5 Hanwen Tong,3 Weihong Ge,1,5 Chenxiao Jiang1,5 1Department of Pharmacy, Nanjing Drum Tower Hospital, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 2School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 3Department of Emergency Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People’s Republic of China; 4Department of Emergency Medicine, Nanjing Drum Tower Hospital, School of Clinical Medicine, Xuzhou Medical University, Nanjing, Jiangsu, People’s Republic of China; 5Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chenxiao Jiang, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Zhongshan Road No. 321, Nanjing, Jiangsu, People’s Republic of China, Email sharejcx@163.com Weihong Ge, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Zhongshan Road No. 321, Nanjing, Jiangsu, People’s Republic of China, Email glg6221230@163.comPurpose: To evaluate the efficacy of glucocorticoid treatment in critically ill patients with severe fever with thrombocytopenia syndrome (SFTS) and to assess whether glucocorticoid use increases the risk of fungal infections.Patients and Methods: A retrospective cohort study was conducted involving confirmed SFTS patients from a tertiary hospital. …”
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Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells by Cheng C, Sun M, Li J, Xue Y, Cai X, Liu J, Wang X, Xu S, Xie Y, Zhang J

“…Here, we screened nucleic acid aptamers against the widespread HuNoV GII.4 and emerging HuNoV GII.17.Methods: After ten rounds of sieving for HuNoV GII.4 and GII.17 virus-like particles (VLPs), eight ssDNA aptamers were generated and characterized for each genotype.Results: Four of the eight aptamers generated for GII.4 VLP had dissociation constants (Kd) less than 100 nM, and all aptamers for GII.17 VLP had Kd less than 10 nM. …”
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Explainable Prediction of Long-Term Glycated Hemoglobin Response Change in Finnish Patients with Type 2 Diabetes Following Drug Initiation Using Evidence-Based Machine Learning App... by Chandra G, Lavikainen P, Siirtola P, Tamminen S, Ihalapathirana A, Laatikainen T, Martikainen J, Röning J

“…It also aimed to identify the predictors associated with these changes.Patients and Methods: Electronic health records (EHR) from 10,139 type 2 diabetes patients in North Karelia, Finland, were used to train models integrating randomized controlled trial (RCT)-derived HbA1c change values as predictors, creating offset models that integrate RCT insights with real-world data. …”
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Short-Term Effectiveness of Ustekinumab in Crohn’s Disease: Results from a Real-World Retrospective Multicenter Study in China by Zhu X, Fang X, Wang Q, Li M, Zhang K, Xie L, Niu X, Wang S

“…Our study is a real-world retrospective multicenter study aimed at exploring the effectiveness of ustekinumab in CD patients and comparing the effectiveness of first line and second line treatments.Methods: Laboratory indicators, CD activity index (CDAI) and simple endoscopic score for CD (SES-CD) scores of patients at the 8th, 16th and 24th weeks of treatment were collected, and the clinical remission rate, clinical response rate, endoscopic remission rate and endoscopic response rate were calculated, and the patients were divided into first line group and second line group for comparison.Results: A total of 102 patients were treated with ustekinumab, and 56 patients with a clinical data integrity rate greater than 70% were ultimately included. …”
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Efficacy of Cooling Blankets for Early Temperature Management in Heat Stroke Patients: A Multicenter Retrospective Cohort Study by Chen L, Jin D, Gong Z, Lu L, Zhao J, Xu S, Yang X, Zhang Y, Feng X

“…This study aimed to assess the cooling effect of the cooling blanket within the first 24 hours after emergency department admission in patients with heat stroke.Methods: Retrospective data were collected from six hospitals. …”
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ALBI Grade Analyses of TACE Combined with Anti-Angiogenesis Therapies Plus PD-1 Inhibitors versus Anti-Angiogenesis Therapies Plus PD-1 Inhibitors in Advanced HCC by Hong X, Hu D, Zhou WJ, Wang XD, Huang LH, Huang TA, Guan YW, Qian J, Ding WB

“…Xin Hong,1,* Di Hu,2,* Wen-Jie Zhou,3,* Xiu-De Wang,4 Li-Hua Huang,5 Tian-An Huang,1 Yi-Wei Guan,1 Jingyu Qian,6 Wen-Bin Ding1 1Department of Interventional Radiology, Affiliated Hospital 2 of Nantong University, Nantong, People’s Republic of China; 2Department of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 3Department of Interventional Radiology, Northern Jiangsu People’s Hospital, Clinical Medical College of Yangzhou University, Yangzhou, People’s Republic of China; 4Department of Interventional Radiology, Nantong Second People’s Hospital, Nantong, People’s Republic of China; 5Department of Interventional Radiology, Nantong Haimen District People’s Hospital, Nantong, People’s Republic of China; 6Department of Interventional Radiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wen-Bin Ding, Department of Interventional Radiology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, People’s Republic of China, Tel/Fax +86 15951302169, Email 15951302169@163.com Jingyu Qian, Department of Interventional Radiology, the First Affiliated Hospital of Bengbu Medical University, Bengbu, 233004, People’s Republic of China, Tel/Fax +86 13004081388, Email jyqian1388@163.comObjective: To evaluate the baseline albumin-bilirubin (ALBI) grade’s role in advanced hepatocellular carcinoma (HCC) receiving transarterial chemoembolization (TACE) plus anti-angiogenesis therapies and PD-1 inhibitors (TACE+TP) versus anti-angiogenesis therapies and PD-1 inhibitors (TP).Methods: This multicenter retrospective study enrolled advanced HCC undergoing TACE+TP or TP from January 2019 to June 2023 at three hospitals in China. …”
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Mechanistic Insights Into Ganoderma Lucidum for Diabetes Treatment via Network Pharmacology and Validation by Guo S, Yang L, Zhou J, Luo W, Nie B, Zhong X, Liu D, Kang X

“…This study was aimed to explore the active ingredients and mechanism of G. lucidum in the treatment of diabetes.Materials and Methods: Relevant compounds and targets of Ganoderma were collected from the TCMSP database, BATMAN-TCM database, relevant literature and PubChem. …”
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