Modeling the epidemiological impact of the UNAIDS 2025 targets to end AIDS as a public health threat by 2030. by John Stover, Robert Glaubius, Yu Teng, Sherrie Kelly, Tim Brown, Timothy B Hallett, Paul Revill, Till Bärnighausen, Andrew N Phillips, Christopher Fontaine, Luisa Frescura, Jose Antonio Izazola-Licea, Iris Semini, Peter Godfrey-Faussett, Paul R De Lay, Adèle Schwartz Benzaken, Peter D Ghys

“…This study reports on efforts to use mathematical models to estimate the impact of achieving those targets.<h4>Methods and findings</h4>We simulated the impact of achieving the targets at country level using the Goals model, a mathematical simulation model of HIV epidemic dynamics that includes the impact of prevention and treatment interventions. …”
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Relationship Between Sleep Time and Depressive Symptoms in Middle-Aged and Elderly Chinese: Mediating Role of Body Pain by Yang Z, Li B, Ma D, Lv Y, Qiu X, Zhang W, Wang J, Zhang Y, Xu C, Deng Y, Li J, Zhen X, Zhang J

“…This study seeks to elucidate the interconnections between these three elements.Methods: The study used 2020 CHARLS data for analysis. …”
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A randomized comparison of intramuscular high-dose versus oral maintenance vitamin D to prevent severe exacerbations in deficient/insufficient asthmatic children by Khalid Alansari, MD, Bruce L. Davidson, MD, MPH, Michael F. Holick, MD, PhD

“…Objective: We sought to compare high-dose intramuscular (IM) + daily oral maintenance vitamin D dose versus daily oral maintenance vitamin D dose for preventing asthma exacerbations in prospectively randomized vitamin D–deficient/insufficient children aged 5 to 14 years with moderate to severe asthma. Methods: This is an accessory post hoc analysis from a larger vitamin D supplementation trial, analyzing results of the randomized stratum of older children receiving the high dose presenting with emergency department (ED) visits for asthma and baseline blood 25-hydroxyvitamin D concentration less than or equal to 25 ng/mL. …”
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Recent Advances in the Delivery of Bone Morphogenetic Proteins for Targeting Glioma: An Updated Review by Bao H, Chen Y, Zong Y, Jin K, Lan H

“…Hydrogels, scaffolds, and microspheres’ local delivery methods are also discussed as prospective options. …”
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The use of Revenue-sharing Contracts in Two-level Supply Chain Coordination with the Presence of Vendor-managed Inventory and Advertising Investment by Bahareh Osuli, Mohammad Reza Gholamian, Maryam Noroozi

“…Additionally, in the developed model, the demand function incorporates a multiplicative factor of elements influencing the profit function, such as retail price, retailer, and manufacturer advertising investments. MethodsIn this article, we study the coordination in a two-level supply chain including one manufacturer and multiple retailers under a revenue-sharing contract, where the pricing and advertising investment strategy of each member of the supply chain is implemented despite vendor-managed inventory in a centralized supply chain. …”
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Risk factors for hospitalization at the pediatric intensive care unit among infants and children younger than 5 years of age diagnosed with infectious diseases by Judah Freedman, Eugene Leibovitz, Ruslan Sergienko, Amalia Levy

“…The objectives of this study were to identify independent risk factors for PICU hospitalization with an infectious disease in children <5 years of age. Methods: In southern Israel, two populations live side by side: the middle–high income Jewish population and the low-income Bedouin population, both receiving equal and free medical care at the only tertiary medical center in the area. …”
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Suppression of Inflammation by Si Miao San in Experimental Rheumatoid Arthritis Through Modulation of the AKT/ROS/Autophagy Axis by Zhang H, Jiang H, Wei Q, Xu J, Zhao Z, Sun Y, Lu Q

“…The goal of this study was to explore the therapeutic effects of Si Miao San (SMS) on adjuvant-induced arthritis in mice and the regulatory mechanisms of NETs both in vivo and in vitro.Methods: SMS decoctions were identified using LC-MS/MS analysis and TCMSP. …”
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A novel equation synthesis for estimating resting energy expenditure in prostate cancer patients by Nilüfer Acar Tek, Tevfik Koçak, Süleyman Yeşil, Tevfik Sinan Sözen

“…The purpose of this research was to evaluate the accuracy of the established novel equation for predicting REE in malign and benign prostate patients versus the accuracy of the previously used predictive equations based on REE measured by indirect calorimetry. Methods The study was conducted as a cross-sectional case-control study and between December 2020 and May 2021 with 40 individuals over the age of 40 who applied to the Urology Clinic of Gazi University Faculty of Medicine. …”
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Associations Between Renal Dysfunction Subtypes and Vertebral Fracture in Patients with Type 2 Diabetes: A Longitudinal Study by Hu N, Zhang Y, Wei Z, Yu R, Zhang Y, Chen X

“…In this longitudinal study, we evaluated the associations between different subtypes of renal dysfunction and vertebral fracture (VF) in patients with type 2 diabetes.Methods: This study recruited T2DM patients aged 50 years or older whose computed tomography (CT) imaging screening revealed no VFs from January 2019–December 2021. …”
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Prognostic Value of Gd-BOPTA Enhanced MRI in Solitary Resected Hepatocellular Carcinoma Without Microvascular Invasion by Zhang J, Luo H, Li Y, Feng Y, Pan X, Ouyang B, Nian G, Jia N, Li Y

“…Juan Zhang,1,2,&amp;ast; Hongmei Luo,2,&amp;ast; Yinqiao Li,2,&amp;ast; Yayuan Feng,2 Xingpeng Pan,2 Beilei Ouyang,2 Guihong Nian,2 Ningyang Jia,2 Yonggang Li1,3 1Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou City, Jiangsu Province, 215006, People’s Republic of China; 2Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, Shanghai, 200438, People’s Republic of China; 3Institute of Medical Imaging, Soochow University, Suzhou City, Jiangsu Province, 215000, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Ningyang Jia; Yonggang Li, Email ningyangjia@163.com; liyonggang@suda.edu.cnObjective: This study aims to evaluate the prognostic predictive efficacy of Gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance imaging (MRI) in patients with solitary hepatocellular carcinoma (HCC) without microvascular invasion (MVI) and to investigate the potential clinical and imaging parameters for stratifying the risk of recurrence following hepatectomy.Methods: This retrospective study included 134 patients with histopathologically confirmed solitary HCC without microvascular invasion (MVI) from two hospital districts, which divided into the training cohort and validation cohort. …”
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Effects of escitalopram with a Chinese traditional compound Jiuweizhenxin-keli on mismatch negativity and P50 in patients with major depressive disorders by Kuang W, Tian L, Yue L, Li J

“…Weihong Kuang,1,* Liantian Tian,2,* Lili Yue,1 Jin Li1 1Department of Psychiatry and Mental Health Center, West China Hospital, Sichuan University, Chengdu, People&amp;rsquo;s Republic of China; 2Occupational Respiratory Disease Research Center, No 4 West China Hospital/West China School of Public Health, Sichuan University, Chengdu, People&amp;rsquo;s Republic of China *These authors contributed equally to&amp;nbsp;this work Objective: The objective of this study was to investigate the therapeutic effects of escitalopram in conjunction with Jiuweizhenxin-keli on neuroelectrophysiology in patients with major depressive disorders (MDD).Patients and methods: Patients with depressive episode of MDD according to the criteria of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, were randomly assigned to Esc group (30 patients) receiving escitalopram treatment and JK group (30 patients) treated with a combination of escitalopram and Jiuweizhenxin-keli. …”
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Relationship Between Obstructive Sleep Apnea and Enuresis in Children: Current Perspectives and Beyond by Wang Z, Zhang P, Shi R, Yang S, Liu K, Zhou Z, Li Q

“…This review summarizes the relationship between NE and OSA and how to treat them, aiming to provide a reference for the clinical treatment of OSA and NE in children.Methods: All pertinent original publications to this point from PubMed database have been collected, including investigations on the connection between OSA and NE as well as studies on the mechanism and therapeutic strategy of NE in children with OSA.Results: There is a bidirectional relationship between OSA and NE in children. …”
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Evaluation of the Efficacy of a Nomogram to Predict Multidrug-Resistant Pulmonary Infections Based on Data from Neurosurgery Ward Patients by Zhou R, Chen X, Jia H, Duan W

“…Ran Zhou,1,&amp;ast; Xiaolong Chen,2,&amp;ast; Hengmin Jia,3 Wen Duan4 1Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 2Department of Pharmacy, The Second People’s Hospital of Chizhou, Chizhou, Anhui, 247100, People’s Republic of China; 3Department of Infection Office, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China; 4Department of Orthopedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Wen Duan, Department of Orthopedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, People’s Republic of China, Email duanwen1717@gmail.comObjective: This study aimed to construct and evaluate a nomogram based on data from neurosurgery ward patients to predict the probability of multidrug-resistant (MDR) pneumonia occurrence.Methods: We retrospectively collected clinical data, early laboratory test results, and physician prescriptions for 35 variables from patients. …”
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Intraoperative Intraluminal Endoscopy in the Surgical Treatment of Patients with Esophageal Diverticula of Various Localization by A. L. Shestakov, M. V. Khrustaleva, M. E. Shahbanov, N. A. Bulganina, T. T. Bitarov, I. A. Boeva, A. T. Tskhovrebov, I. A. Tarasova, O. V. Rykov, I. M. Selivanova, A. A. Bezaltynnykh

“…To improve the results of surgical treatment of patients with esophageal diverticulum of various localization using intraoperative intraluminal endoscopy. Materials and Methods: The Department of Surgery of the Esophagus and Stomach, the Petrovsky National Research Centre of Surgery, has accumulated a large experience in treating diverticulosis patients. …”
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Implementation of Therapeutic Patient Education (TPE) in Primary Care, as Perceived by Professionals: A Narrative Review by Kirkove D, Durieux N, Allory E, Louis G, Gagnayre R, Pétré B

“…The review included 12 articles, revealing that TPE practices in primary care are often underdeveloped, primarily individual, and focused on oral, informative methods. Obstacles identified by healthcare professionals primarily fall into two TDF domains: environmental context (eg, lack of time, resources, and fragmented healthcare systems) and individual skills deficits. …”
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The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy by Wang X, Shu X, Pei W, Yuan C, Su X, Xiong J, Chen W, Zhang G, Jie Z, Liu Y

“…Although the prevalence of SO is on the rise, there is a notable paucity of research examining the impact of SO on weight loss efficacy following laparoscopic sleeve gastrectomy (LSG).Purpose: To investigate the impact of SO on weight loss outcomes and recurrent weight gain following LSG.Methods: We retrospectively gathered clinical data of 104 patients with obesity who underwent LSG in our hospital between January 2020 and September 2023. …”
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Efficacy and Long-Term Outcomes of Tacrolimus versus Cyclophosphamide and Mycophenolate Mofetil in the Management of Pediatric IgA Vasculitis Nephritis: A Cohort Study in Single-Ce... by Han Y, Yang F, Zhou L, Yang J, Yang Y, Wang Y, Qiu L, Zhang Y, Zhou J

“…Therefore, the objective of this study is to compare the effectiveness and long-term outcome of TAC, CYC, and MMF in combination with glucocorticoid in pediatric IgAVN.Patients and Methods: A retrospective analysis was conducted on children with grade II–V IgAVN by renal biopsy at Tongji Hospital from November 2011 to October 2021. …”
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Adipose-Derived Stem Cell Products and Combination Therapies for the Treatment of Pathological Scars: A Review of Current Preclinical and Clinical Studies by Alfarafisa NM, Chou Y, Santika R, Riestiano BE, Soedjana H, Syamsunarno MRAA

“…The effectiveness of ADSC products as monotherapies and in combination with other treatments has also been explored.Methods: A comprehensive literature search followed the PICO framework, utilizing electronic databases such as PubMed and Scopus. …”
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The Association Between Neonatal Respiratory Distress Syndrome and Plasma IgG N-Glycosylation: A Case-Control Study by Wang Y, Shen Q, Yan R, Wang M, Xu M, Chen H, Li D

“…However, its implications and clinical significance in NRDS remain to be clarified.Methods: To determine the effect of IgG N-glycosylation on NRDS, we recruited 88 NRDS participants and 120 control participants from December 2021 to September 2022. …”
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Trajectories and Interactions of Dyadic Coping and Depression in Patients After Thrombolysis for Acute Ischemic stroke: A Longitudinal Study in China by Liu J, Xu L, Li XQ, Chen D, Ji KX, Qiu LF

“…Jingxiu Liu,&amp;ast; Lei Xu,&amp;ast; Xiao-qin Li,&amp;ast; Dandan Chen, Kang-xiang Ji, Lan-feng Qiu Department of Emergency Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215009, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Lan-feng Qiu, Department of Emergency Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215009, People’s Republic of China, Email 15062100130@163.comObjective: To explore the developmental trajectory of dyadic coping and depression in stroke patients and the predictive relationship between the two and to provide a theoretical basis for improving depression in stroke patients.Design: A longitudinal study.Methods: Two hundred and forty-two stroke patients who underwent thrombolysis in the emergency department of our hospital from January 2023 to March 2024 were selected as the study subjects, and their dyadic coping and depression were tracked and investigated in T1 (after thrombolysis), T2 (3 months after the disease), and T3 (6 months after the disease), and the data were analyzed using a cross-lagged model and latent variable growth model.Results: Two hundred and twelve valid serial questionnaires were recovered at the completion of the three time points. …”
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