Interprofessional collaboration on oral health for frail home-dwelling older people: a focus group study on needs and barriers experienced by general practitioners and community ph... by Natalie Hoste, Ellen Baele, Aster De Vleeschauwer, Fien Mertens, Louise Poppe, Barbara Janssens, Peter Pype

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Vaccination against the SARS-CoV-2 in individuals with comorbidities by S A Berns, M G Chashсhin, A Yu Gorshkov, O V Zhdanova, L N Ryzhakova, O A Litinskaya, O M Drapkina

“…To assess post-vaccination period and the incidence of coronavirus disease 2019 (COVID-19) in comorbid individuals vaccinated and revaccinated against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Material and methods. The study was conducted within the prospective SATURN registry, which included individuals who received various revaccination regimens against the SARS-CoV-2 (homoand heterologous regimens) based on a combination of two vaccines (GamCOVID-Vac and CoviVac). …”
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An Integrated Machine Learning Framework for Developing and Validating a Diagnostic Model of Hub Genes Related to Lipid Metabolism in Chronic Rhinosinusitis by Xiong P, Liu L, Pi J, Wang J, Lu T, Ke X, Jiang Y, Shen Y, Yang Y

“…Panhui Xiong,1,* Lei Liu,1,2,* Jingting Pi,3,* Ji Wang,1 Tao Lu,1 Xia Ke,1 Yu Jiang,1 Yang Shen,1 Yucheng Yang1 1Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, Mianyang Central Hospital, Mianyang, 621000, People’s Republic of China; 3Department of Otolaryngology Head and Neck Surgery, Yongchuan Hospital Affiliated of Chongqing Medical University, Chongqing, 402160, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yucheng Yang, Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China, Email yychxh@163.com Yang Shen, Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China, Email sy_smile@sina.cnPurpose: The study aimed to identify key genes related to lipid metabolism in chronic sinusitis and understand their biological implications, considering the growing interest in the association between chronic sinusitis - a complex inflammatory condition - and lipid metabolism due to lipids’ role in inflammation and immunity.Methods: Gene expression data from bulk - RNA sequence was analyzed and intersected with lipid metabolism genes and WGCNA module genes from the MSigDB database. …”
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Impact of Initial Heart Rate, Diastolic Pressure, and Pulse Pressure on Prognostic Outcomes in Heart Failure Patients with Mildly Reduced Ejection Fraction by Hu H, Liu Z, Zeng J, Jiang M

“…This study aims to elucidate their effects on HFmrEF patient outcomes.Methods: We retrospectively analyzed 1,653 hFmrEF patients treated at Xiangtan Central Hospital (2015– 2020). …”
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Novel Cross Screw with Staple for First MTP Joint Arthrodesis Compared to Dorsal Plate Fixation: Retrospective Clinical and Radiographic Evaluation by Stephen R. Arndt MD, Shirin Zahra BS, Mark Moldavsky MS

“…Dorsal plating (DP) group for 1st MTP joint was used for as control group. Methods: Pre-op and post-op Visual Analog Score (VAS) were assessed. …”
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Promotion of Random Flap Neovascularisation in Rats with Diabetes Using Botulinum Toxin Type A Through the HIF-1α/VEGF Pathway by Yan HJ, Lin FM, Li JJ, Qin H, Wang YH, You CH

“…Hong-Jie Yan,1,* Fang-Ming Lin,2,* Jing-Jing Li,1 Hao Qin,1 Yi-He Wang,1 Chuan-Hua You1 1Department of Plastic and Cosmetic Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, 570102, People’s Republic of China; 2Department of Vascular Surgery, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, 570100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuan-Hua You, Department of Plastic and Cosmetic Surgery, The First Affiliated Hospital of Hainan Medical University, No. 31 of Longhua Street, Longhua District, Haikou, 570102, People’s Republic of China, Tel +8615120793168, Fax +86-1083161294, Email youchuanhua3063@163.comObjective: This study aimed to investigate the effects of botulinum toxin type A (BoTA) on the neovascularisation of diabetic flaps through the factor-1alpha (HIF-1α)/vascular endothelial growth factor (VEGF) pathway.Methods: A total of 60 male Wistar rats (250– 300 g) were randomly divided into 4 groups. …”
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A Model Predicting Occult Metastases in Lateral Lymph Nodes in pN1a Stage Papillary Thyroid Cancer by Chen Y, Chen S, Mei Y, Wang F, Wei T, Wei C

“…Yan Chen,1,2,* Shaohua Chen,2,* Yujia Mei,3 Fengwei Wang,4 Teng Wei,2 Changyuan Wei1 1Department of Breast and Thyroid Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, People’s Republic of China; 2Department of Breast and Thyroid Surgery, Liuzhou People’s Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi, People’s Republic of China; 3Department of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 4Health Management Centre, Liuzhou People’s Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Changyuan Wei, Email changyuanwei@gxmu.edu.cnObjective: This study aimed to develop and validate a nomogram for predicting occult lateral neck lymph node metastasis (LLNM) in patients with pN1a papillary thyroid carcinoma (PTC), addressing the clinical controversy surrounding prophylactic lateral neck dissection (PLND).Methods: A retrospective analysis was conducted on 128 pN1a PTC patients who underwent total thyroidectomy with bilateral central lymph node dissection and ipsilateral PLND between 2020 and 2023. …”
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Oncostatin M Drives Th2 Polarized Allergic Airway Inflammation Through Fibroblast Reprogramming and Endoplasmic Reticulum Stress by Zhang H, Chen X, Liu L, Zheng H, Yang X, Yin K, Yao Q, Li L, Yang P

“…This study investigates the role of OSM in dust mite extract (DME)-induced allergic airway inflammation and identifies a novel mechanism by which OSM drives Th2-polarized inflammation.Methods: A murine model of DME-induced airway inflammation was established. …”
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Using ChatGPT to Improve the Presentation of Plain Language Summaries of Cochrane Systematic Reviews About Oncology Interventions: Cross-Sectional Study by Jelena Šuto Pavičić, Ana Marušić, Ivan Buljan

“…ObjectiveThis study assessed whether a large language model (eg, ChatGPT) can improve the readability and linguistic characteristics of Cochrane PLSs about oncology interventions, without changing evidence synthesis conclusions. MethodsThe dataset included 275 scientific abstracts and corresponding PLSs of Cochrane systematic reviews about oncology interventions. …”
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The Causal Association Analysis between Depression and Cerebrospinal Fluid: From the Perspective of Mendelian Randomization by Zhang Y, Wu P, Liu Z

“…Although cerebrospinal fluid (CSF) biomarkers have been identified as potential indicators and therapeutic targets for depression, their causal relationship with MDD remains unclear.Methods: We analyzed publicly available CSF metabolomics and genotype data, quantifying 338 distinct metabolites. …”
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Predictive Value of Kidney Failure Risk Equation and Neutrophil Gelatinase-Associated Lipocalin for Chronic Kidney Disease Progression in Chinese Population – A Retrospective... by Shi L, Liao Y, Chen Y

“…Liu Shi,1,* Youxin Liao,2,* Yue Chen3 1Department of Critical Care Medicine, Jiangjin Central Hospital, Chongqing, 402260, People’s Republic of China; 2Department of Medical Administration, Jiangjin Central Hospital, Chongqing, 402260, People’s Republic of China; 3Department of Oncology, Jiangjin Central Hospital, Chongqing, 402260, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yue Chen, Department of Oncology, Jiangjin Central Hospital, No. 725, Jiangzhou Road, Dingshan Street, Jiangjin District, Chongqing, 402260, People’s Republic of China, Tel +86-15823491696, Email wenlinlin0606@163.comObjective: To analyze the independent associations of the Kidney Failure Risk Equation (KFRE) and neutrophil gelatinase-associated lipocalin (NGAL) with end-stage renal disease (ESRD) among patients with chronic kidney disease (CKD) stages 3– 5 in China and evaluate their predictive values for ESRD.Patients and Methods: A total of 716 patients with CKD stages 3– 5 at the time of the initial renal medicine referral were retrospectively enrolled, and the study outcome was the observed incidence of ESRD at 2 years after the initial referral. …”
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Identification and Characterization of Genes Associated with Intestinal Ischemia-Reperfusion Injury and Oxidative Stress: A Bioinformatics and Experimental Approach Integrating Hig... by Xie Y, Yang M, Huang J, Jiang Z

“…Identifying and characterizing genes associated with the oxidative stress response can offer valuable insights into potential therapeutic targets for managing IIRI.Patients and Methods: The IIRI dataset was sourced from the NCBI Gene Expression Omnibus Database (GEO), while oxidative stress genes were obtained from the Genecards database. …”
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Comparative Study of Vault Measurement by Pentacam, Casia2, and RTVue in Myopic Eyes After Implantable Collamer Lens Implantation by Liu F, Xu Y, Ye Y, Zhang Z, Niu L, Yao P, Wang X, Zhou X, Zhao J

“…USA).Methods: This comparative study recruited 95 eyes of 50 patients (mean age: 28.40± 4.51, male/female 15/35) who underwent implantable collamer lens (ICL) implantation for myopia correction. …”
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THE ECONOMIC TRANSFORMATION: THE ROLE OF SUSTAINABLE BANKING IN QUALITY GROWTH by PULBERE (GHELASE) CARMEN CORNELIA, NECULITA MIHAELA

“…This research explore how sustainable banking methods and economic growth are connected by studying the effects of financial inclusion and green bonds on the Human Development Index (HDI). …”
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Follow-up of Surgical and Nonsurgical Patients With Pulmonary Aspergillosis: A Real-World Study by Chen Z, Shang Y, Wasti B, Ou Y, Gong S, Xiang X, Ouyang R

“…The purpose of this study was to investigate the diagnosis and treatment, follow-up results and prognostic factors of PA patients in the real world, so as to deepen our understanding of PA and improve the prognosis of PA patients.Materials and Methods: Eligible patients with pathologically diagnosed PA (n = 125) were retrospectively enrolled and followed up. …”
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Near-Peer Training: Impact of a Single Session on Students’ OSCE Performance by Alves AS, Taramarcaz V, Cerutti B, Genevay S, Schiffer E, Junod Perron N

“…This study aims to assess the impact of a single clinical skill NPT session on students’ overall objective performance at a summative OSCE.Patients and Methods: This prospective study evaluated the impact of a two-hour NPT session focused on three system-related clinical situations on overall clinical performance. …”
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LIPUS Responsive Dopamine-Modified PVDF Piezoelectric Nanofiber Membrane for Full-Thickness Skin Wound Healing by Zhang Z, Liu L, Wang H, Xie W, Zhai W, Wen L, Zhang B, Liu K, Zhang X, Liu S, Huang L, Li D, Zhou Y

“…This study introduces a portable approach for promoting scarless healing and skin appendage regeneration by utilizing low-intensity pulsed ultrasound (LIPUS) activated piezoelectric electrospun membranes to modulate the local electrical environment.Methods: Dopamine-modified polyvinylidene fluoride (DA/PVDF) nanomembranes were fabricated via electrospinning, followed by piezoelectric characterization under varying LIPUS stimulation. …”
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Inhibition of Colorectal Cancer by Perillaldehyde Through Targeting SRD5A1 to Induce Autophagy via the PI3K/AKT Pathway by Leng Z, Zhang Y, Guo M, Chen Y, Wang Z

“…This study aims to assess the therapeutic potential of PAH against CRC and to clarify its mechanisms of action, providing a rationale for PAH as a promising candidate for anti-CRC therapy.Methods: In vitro, we used CCK-8, colony formation, EdU assays, flow cytometry, and Western blotting to assess the effects of PAH on CRC cell proliferation and apoptosis. …”
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Quantitative examination of video-recorded NHS Health Checks: comparison of the use of QRISK2 versus JBS3 cardiovascular risk calculators by Christopher J Gidlow, Sarah Grogan, Lisa Cowap, Elizabeth Cottrell, Ruth Chambers, Naomi J Ellis, Victoria A Riley, Diane Crone, David Clark-Carter

“…Recruitment was stratified by patients’ age, gender and ethnicity.Methods Video recordings of NHSHC were coded, second-by-second, to quantify who was speaking and what was being discussed. …”
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Using A Neural Network to Generate Images When Teaching Students to Develop an Alternative Text by Yekaterina A. Kosova, Kirill I. Redkokosh, Pavel O. Mikheyev

“…It has been suggested that a neural network for generating images from text descriptions can act as a tool for checking the relevance of the developed text alternatives.Materials and methods. The study was carried out in April-May 2023. 17 undergraduate students studied the requirements for developing text alternatives, completed initial text descriptions for three proposed photographs, and then corrected the text using the Kandinsky 2.1 neural network according to the algorithm: generating an image from the description; visual comparison of the resulting image with the original; returning to editing the description or ending the process. …”
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