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9241
Mediating Effects of Sleep Problems and Emotional Symptoms in the Relationship Between Chronotype and Self-Harm Among Adolescents Aged 11–19 Years
Published 2025-03-01“…This study aims to explore the influence of chronotype on self-harm among adolescents and further investigate the mediating role of sleep problems and emotional symptoms.Participants and Methods: The study was conducted between April and June 2022, involving 13 junior and senior high schools in Tianjin. …”
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9242
Functional and Structural Network Alterations in HIV-Associated Asymptomatic Neurocognitive Disorders: Evidence for Functional Disruptions Preceding Structural Changes
Published 2025-04-01“…Using multimodal MRI and large-scale brain network analysis, we aimed to investigate alterations in functional networks, structural networks, and functional-structural coupling in persons with ANI.Patients and Methods: A total of 95 participants, including 48 healthy controls and 47 persons with HIV-ANI, were enrolled. …”
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9243
Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review
Published 2025-03-01“…(2) What are the main clinical considerations for low-cost eHealth technology–based rehabilitation? MethodsComprehensive literature searches were conducted in PubMed, Web of Science, Scopus, Embase, and Google Scholar using predefined inclusion criteria based on the Population, Intervention, Comparison, Outcome, and Study Design (PICOS) framework. …”
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9244
Central Hemodynamics and Extravascular Lung Water Index in Varying Degrees of Community-Acquired Pneumonia
Published 2015-09-01“…Objective: to assess the specific features of central hemodynamics (CH), extravascular lung water index (EVLWI), and pulmonary oxygenizing function in patients with different outcomes of treatment for severe communityacquired pneumonia (CAP).Subjects and methods. The retrospective study enrolled 57 patients with CAP. …”
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9245
Number of Retrieval Attempts and the Association of Intravenous Tirofiban with Symptomatic Intracranial Hemorrhage in Patients with Successful Endovascular Therapy: Results of the...
Published 2024-11-01“…Xiangxiang Peng,1,* Changwei Guo,2,* Jie Yang,2 Shitao Fan,2 Xu Xu,2 Jinfu Ma,2 Zhixi Wang,2 Shihai Yang,2 Wenjie Zi,2 Xianjun Huang,1 Hongjun Wang3 1Department of Neurology, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui Province, People’s Republic of China; 2Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, People’s Republic of China; 3Department of Neurology, Chongqing Fengdu People’s Hospital, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xianjun Huang, Department of Neurology, Yijishan Hospital of Wannan Medical College, No. 92 Zheshan Road, Wuhu, Anhui Province, 241000, People’s Republic of China, Tel +86-553-5739543, Email doctorhuangxj@hotmail.com Hongjun Wang, Department of Neurology, Chongqing Fengdu People’s Hospital, No. 214, West Section of Pingdu Avenue, Sanhe Town, Fengdu County, Chongqing, 408200, People’s Republic of China, Email whj13364012222@163.comPurpose: To investigate the relationship between intravenous tirofiban, the number of retrieval attempts and symptomatic intracranial hemorrhage (sICH) in patients with successful EVT.Patients and Methods: We used the data from the Endovascular Treatment With versus Without Tirofiban for Patients with Large Vessel Occlusion Stroke (RESCUE BT) Trial. …”
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9246
Combining Super-Resolution Imaging and Shear Wave Elastography for Enhanced Risk Assessment of Moderate-to-Severe Renal Fibrosis in Chronic Kidney Disease Patients
Published 2025-06-01“…Xingyue Huang,* Yao Zhang,* Yugang Hu, Juhong Pan, Xin Huang, Jun Zhang, Huan Pu, Yueying Chen, Qing Deng, Qing Zhou Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, 430061, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qing Zhou, Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, No. 99 of Zhangzhidong Road, Wuhan, 430061, People’s Republic of China, Tel +86027-88041911, Email qingzhou@whu.edu.cn Qing Deng, Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, No. 99 of Zhangzhidong Road, Wuhan, 430061, People’s Republic of China, Tel +86027-88041911, Email wudadq@163.comObjective: This study aims to evaluate the diagnostic efficacy of shear wave elastography (SWE) and super-resolution imaging (SRI) in detecting moderate-to-severe renal fibrosis (MSRF) among patients with chronic kidney disease (CKD).Methods: In this prospective study, 202 CKD patients who underwent SWE and SRI prior to renal biopsy were enrolled. …”
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9247
Impact of the Timing of Protective Stoma Reversal on Survival in Rectal Cancer Patients Undergoing Postoperative Adjuvant Chemotherapy: A Retrospective Single Center Study
Published 2025-04-01“…This study aimed to investigate the effect of stoma closure before or after adjuvant chemotherapy on survival and stoma-related complications.Methods: A retrospective analysis was conducted on 144 patients who underwent radical rectal cancer surgery, prophylactic ileostomy and adjuvant chemotherapy from June 2018 to June 2021. 104 had their stoma reversal before adjuvant chemotherapy completion (Before group) and 40 after adjuvant chemotherapy completion (After group).Results: There were no significant differences between the groups regarding demographics, clinical characteristics, perioperative complications, OS, or DFS. …”
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9248
Association Between Diurnal Temperature Range and Risk of Cardiomyopathy-Induced Hospitalisation in Henan, China: A Time-Series Study
Published 2025-01-01“…Here, we determined whether an association exists between DTR and CM hospitalisations in vulnerable populations.Methods: CM admission data (2016– 2021) were collected from seven tertiary hospitals in Henan.We used a GAM combined with a distributed lag non-linear model (DLNM) to investigate the delayed effects of DTR on daily hospitalisations for CM.Stratified analysis was performed in subgroups according to sex, age, and season. …”
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9249
Recombinant Hydrophobic Polypeptide MBAY Loaded Into SPION-Exosome Realizes Sustained-Release to Improve Type 2 Diabetes Mellitus
Published 2025-04-01“…Therefore, in our study, the transmembrane hydrophobic structure of the exosome signature protein CD81 was fused with BAY 55-9837 to obtain MBAY with sustained-release capability.Methods: MBAY was fabricated via genetic engineering, and the dissociation constant (Kd) was determined to assess its affinity for vasoactive intestinal peptide receptor type 2 (VPACII). …”
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9250
A Machine-Learning Model for the Prediction of Triple-Negative Breast Cancer Based on Multiparameter MRI
Published 2025-07-01“…Yuxin Cai,1,* Yanbo Li,1,* Wenqi Wang,1 Yaqiu Zhou,1 Jingbo Wang,1 Lina Zhang,1,2 Hong Lu1 1Department of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People’s Republic of China; 2Second Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Lu, Department of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People’s Republic of China, Tel +86-18622221319, Email honglu@tmu.edu.cnObjective: To explore the difference between triple-negative breast cancer (TNBC) and non-triple-negative breast cancer (non-TNBC) based on multi-parametric MRI imaging features and construct a prediction model to identify TNBC.Methods: A retrospective study enrolled 1353 women with 1376 malignant lesions who had no additional therapy before surgery between January 2019 and December 2020 in a single center. …”
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9251
Results of direct comparison of the clinical efficacy of ixekizumab and adalimumab: data from the SPIRIT H2H study
Published 2020-09-01“…Objective: to analyze the data available in the literature on the efficacy and safety of ixekizumab (IXE) and adalimumab (ADA) via their direct comparisons in the treatment of psoriatic arthritis (PsA).Patients and methods. The results of the SPIRIT H2H study were analyzed, the aim of which was to investigate the potential superiority of IXE to ADA for arthritis and skin manifestations in a group of patients with active PsA, stable plaque psoriasis with an inadequate response to synthetic disease-modifying antirheumatic drugs (sDMARDs) who had not previously received biological agents (BAs).Design: a 52-week multicenter, randomized, parallel-group study. …”
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9252
A population-based study of neonatal air transport in the Arctic region of Norway from 1994 to 2023
Published 2025-07-01“…Background and aimsRegionalized centralization of moderate and high-risk pregnancies is essential, but a well-organized postnatal transport service is equally important. This study evaluates the overall activity and clinical outcomes of the neonatal air transport team (NATT) at the University Hospital of North Norway (UNN) in Tromsø, covering a large catchment area in the Arctic region of Norway.MethodsMedical data from all neonatal air transports between the years 1994–2023 were recorded prospectively. …”
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9253
Efficacy and Safety of Ultrasound-Guided Pulsed Radiofrequency Therapy of Stellate Ganglion on Refractory Painful Diabetic Peripheral Neuropathy
Published 2024-12-01“…Therefore, the study aimed to explore whether ultrasound-guided pulsed radiofrequency (PRF) therapy of the stellate ganglion (SG) in type 2 diabetes mellitus (T2DM) patients with painful DSPN could decrease pain severity and the need for analgesics.Methods: Fifty-six T2DM patients with refractory painful DSPN were enrolled in this study, who then received bilateral ultrasound-guided PRF therapy of SG. …”
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9254
Exploring Pain Empathy Among Doctors, Nurses and Patients: A Scoping Review
Published 2025-05-01“…Wan-Qiong Zhou,1,* Yi-Tian Gao,2,* Cheng-Rui Zhang,3 Ying Xing,3 Lan-Shu Zhou,2 Wei Luan1 1Department of Nursing, Shuguang Hospital Affiliated With Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2College of Nursing, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 3College of Nursing, Shanghai Jiao Tong University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Luan, Department of Nursing, Shuguang Hospital affiliated with Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai, People’s Republic of China, Tel +86 15921317982, Email luanwei_shuguang@126.com Lan-Shu Zhou, College of Nursing, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, People’s Republic of China, Tel +86 13761801446, Email zhoulanshu@hotmail.comPurpose: This review aims to systematically assess the existing body of research on pain empathy among healthcare workers and patients, with the goal of enhancing both understanding and clinical application.Methods: Studies were retrieved from seven databases: PubMed, EBSCO, The Cochrane Library, Embase, CBM, CNKI, and Wanfang, with a search date limit from database inception to September 13, 2024. …”
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9255
Personality's Time Perspective as a Resource for Overcoming the Identity Crisis at Different Stages of Life Realization
Published 2025-01-01“…Manukyan; methodology for the study of professional identity and personal identity by L.B. Schneider. The methods of statistical analysis (correlation analysis, Mann-Whitney U Test, Kruskal–Wallis test, regression analysis) were used in the processing of the obtained data. …”
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9256
Coverage of continuum of Maternal, Newborn and Child Health (MNCH) care in a nationally representative sample of 40,687 mother–child dyads of India: a report from NFHS-5
Published 2025-08-01“…Nineteen CoC interventions (Y/N) were added (equally-weighted) to construct a composite CoC score. …”
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9257
Increased Incidence of Chronic Obstructive Pulmonary Disease in Women Due to Long-Term Passive Smoking
Published 2025-08-01“…Zhenkun Liu,* Mingzhi Jiao,* Jiling Lv, Qizheng Han Department of Respiratory Medicine, Shandong Second Provincial General Hospital, Jinan, Shandong, 250000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiling Lv, Department of Respiratory Medicine, Shandong Second Provincial General Hospital, No. 4 Duanxing West Road, Jinan, Shandong, 250000, People’s Republic of China, Tel +8615508603200, Email lvjiling1980@163.com Qizheng Han, Department of Respiratory Medicine, Shandong Second Provincial General Hospital, No. 4 Duanxing West Road, Jinan, Shandong, 250000, People’s Republic of China, Tel +8615168863190, Email hanqizheng@163.comObjective: To investigate the impact of long-term passive smoking on the pathogenesis of chronic obstructive pulmonary disease (COPD) in women.Methods: We conducted a community-based cross-sectional study involving 2,360 women aged ≥ 40 years in Jinan, China (October 1, 2022-April 30, 2023). …”
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9258
Outcomes of Total Ankle Replacement are Worse in Patients with Ipsilateral Hindfoot Fusion
Published 2024-12-01“…We hypothesized that TAR patients with ipsilateral hindfoot fusion would have higher rates of revision and worse PROs compared to controls. Methods: A retrospective review of prospectively collected data within an institutional registry was performed. …”
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9259
A New Composite Integrative and Conjugative Element Mediates Multiple Drug Resistance from Streptococcus anginosus to Streptococcus agalactiae
Published 2025-04-01“…Yingting Wang,1,* Taoran Liu,1,* Sida Yi,2 Yuanting Zhu3,4 1Department of Critical Care Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China; 2Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China; 3NHC Key Laboratory of Assisted Circulation, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China; 4Department of Cardiology, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuanting Zhu, Department of Cardiology, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, People’s Republic of China, Tel +86-18501230142, Email zhuyuanting@sysush.comIntroduction: Integrative and conjugative elements (ICEs) are a category of horizontal mobile genetic elements (MGEs) that play important roles in mediating the spread of antimicrobial resistance in Streptococci.Methods: In this study, a novel ICE, namely ICESan 26_rplL, was identified from commensal Streptococcus anginosus through routine silico analyses. …”
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9260
Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation
Published 2025-01-01“…However, there is currently no relevant research to promote gastrostomy wound treatment and tract maturation.Methods: Herein, a nanozyme loaded bioactive hydrogels (MO-HPA) was developed to accelerate tract maturation and inhibit bacteria. …”
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