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8861
Overcoming Clusterin-Induced Chemoresistance in Cancer: A Computational Study Using a Fragment-Based Drug Discovery Approach
Published 2025-05-01“…Quantitative structure-activity relationship (QSAR) analysis revealed that the chemical size and complexity of the fragments significantly contributed to their binding affinity. …”
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8862
Neutrino interaction vertex reconstruction in DUNE with Pandora deep learning
Published 2025-06-01“…Subsequent reconstruction algorithms use this location to identify the individual primary particles and ensure they each result in a separate reconstructed particle. …”
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8863
Highly Accelerated Dual-Pose Medical Image Registration via Improved Differential Evolution
Published 2025-07-01“…Additionally, the algorithm is more suitable for clinical applications due to its lower complexity.…”
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8864
The Model-Driven Design Integration Framework (MDDIF): Introduction to an Optimized Product Development Process and a Design for Manufacturing Case Study
Published 2025-01-01“…The complexity of modern system and manufacturing process development often leads to inefficiencies in responsiveness, cost, and quality. …”
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8865
Modeling and Control of AC Microgrids Under Unbalanced Utility Grid Voltage Using the Invariant-Ellipsoid Method
Published 2025-01-01“…In the presence of asymmetrical power exchange between the microgrid and utility grid, a negative-sequence rejection strategy is applied to ensure that the power transactions remain balanced. …”
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8866
The use of emerging autonomous technologies for ocean monitoring: insights and legal challenges
Published 2025-08-01“…To address the operational and regulatory complexities, States may coordinate collaboration through involvement of the Intergovernmental Oceanographic Commission (IOC), the International Maritime Organization (IMO), and the World Meteorological Organization (WMO), for example. …”
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8867
Transchain: Blockchain-Based Management of Allografts for Enhancing Data Provenance
Published 2025-01-01“…We present six reliable and cost-efficient algorithms, as well as a comprehensive system architecture, to provide valuable insight into system implementation complexity. We have designed an efficient smart contract implementing the proposed algorithms to ensure flawless execution of allograft donation, transportation, and transplantation. …”
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8868
Optimizing Renewable Strategies for Emission Reduction Through Robotic Process Automation in Smart Grid Management
Published 2024-11-01“…However, managing the fluctuations and variability in renewable energy supply presents significant challenges. To address these complexities, it is vital to optimally coordinate flexible resources from source–network–storage–load (SNSL) in a manner that aligns with cross-sectoral emission reduction strategies while enhancing grid stability and efficiency. …”
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8869
Nanobiomaterials-enabled sensors for heavy metal detection and remediation in wastewater systems: advances in synthesis, characterization, and environmental applications
Published 2025-09-01“…Conventional detection and remediation techniques often fall short because of their complexity, cost, and limited efficiency. In response, nanobiomaterials (NBMs)-based sensors have emerged as promising alternatives, offering high sensitivity, specificity, and rapid detection of trace levels of heavy metals such as lead, cadmium, and mercury. …”
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8870
Influence of Tire Parameters on Contact Patch and Axle Force Generation against Short Obstacles Using DOE Approach
Published 2024-09-01“…This algorithm filters the geometries of uneven surfaces and must be seamlessly integrated with a rigid ring model. The complexity of predicting and calculating dynamic tire response increases with varying obstacle dimensions. …”
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8871
A New Reliable Switched-Capacitor-Based High Step-Up Five-Level Inverter
Published 2025-01-01“…Only five switches operate at high frequency, which reduces switching losses, gate driver complexity, and electromagnetic interference. A straightforward control strategy ensures that the inverter delivers a high-quality sinusoidal current waveform to the grid and supports both active and reactive-power flow under various power factor conditions. …”
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8872
AI-enhanced profiling of phage-display-identified anti-TIM3 and anti-TIGIT novel antibodies
Published 2025-03-01“…Of the remaining three candidates, structural models of the complexes formed with their respective targets were generated for 2: T4 (against TIGIT) and 6E9 (against TIM3). …”
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8873
Collision Attacks on Reduced RIPEMD-128
Published 2025-06-01“…As a result, we successfully generate colliding message pairs for 46-step and 54-step reduced RIPEMD-128, with time complexities of approximately 242 and 254, respectively. …”
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8874
Graphical Empirical Mode Decomposition–Convolutional Neural Network-Based Expert System for Early Corrosion Detection in Truss-Type Bridges
Published 2025-07-01“…Detecting corrosion at an early stage is essential to prevent structural failures and ensure safety. This study proposes an expert system based on a novel methodology for corrosion detection using vibration signal analysis. …”
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8875
CAR-NK cells: harnessing the power of natural killers for advanced cancer therapy
Published 2025-05-01“…The success of these therapies hinges on selecting the right tumor-specific targets to ensure effective activation and avoid self-reactivity. …”
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8876
Fault-Tolerant Control Strategy Based on Multi-Phase Wind Power System
Published 2022-07-01“…Finally, the wind turbine is connected to the DC grid via the single bridge arm of the MMC to reduce the complexity of the converter. With 18-phase wind turbines as an example, a Matlab/Simulink simulation model is built to verify the effectiveness of the proposed topology and fault-tolerant control strategy.…”
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8877
Lossless Compression with Trie-Based Shared Dictionary for Omics Data in Edge–Cloud Frameworks
Published 2025-04-01“…The growing complexity and volume of genomic and omics data present critical challenges for storage, transfer, and analysis in edge–cloud platforms. …”
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8878
Machine learning for post-diploma educational and career guidance: a scoping review in AI-driven decision support systems
Published 2025-05-01“…The increasing complexity of career decision-making, shaped by rapid technological advancements and evolving job markets, highlights the need for more responsive and data-informed post-diploma guidance. …”
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8879
A CCP-Based Decentralized Optimization Approach for Electricity–Heat Integrated Energy Systems with Buildings
Published 2025-06-01“…To address the disadvantages of high computational complexity and poor information privacy in centralized optimization, an accelerated asynchronous decentralized alternating direction method of multipliers (A-AD-ADMM) algorithm is proposed, which decomposes the original optimization problem into sub-problems of ES and TS for distributed solving, significantly improving solution efficiency. …”
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8880
On the Design of Super Constellations
Published 2025-01-01“…By utilizing the decision regions formulated by GPD-D, a tight closed-form approximation for the symbol error probability (SEP) of SAPSK constellations is derived, while a detection algorithm with <inline-formula> <tex-math notation="LaTeX">$\mathcal {O}(1)$ </tex-math></inline-formula> time complexity is developed to ensure fast and efficient SAPSK symbol detection. …”
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