The molecular mechanism of NF-κB dysregulation across different subtypes of renal cell carcinoma by Nour Abu Jayab, Alaa Abed, Iman M. Talaat, Rifat Hamoudi

“…RCC is the most common type of kidney cancer and is characterized by complex genetic composition and elusive molecular mechanisms. …”
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Spatio-Temporal Habitat Dynamics of Migratory Small Yellow Croaker (<i>Larimichthys polyactis</i>) in Hangzhou Bay, China by Xiangyu Long, Dong Wang, Pengbo Song, Mengwen Han, Rijin Jiang, Yongdong Zhou

“…Our results showed that the random forest algorithm outperformed other models, with a high sensitivity (95.238) and specificity (99.49), demonstrating its ability to capture complex non-linear relationships between environmental factors and species distribution. …”
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Use of thermoplastically extruded cereal products in nutrition support of patients with chronic pancreatitis and metabolic disorders by I.M. Fomina, T.V. Gavrish, K.S. Malikov, Yu.V. Ivanova, T.I. Viun, S.V. Viun, K.V. Miasoiedov, S.Yu. Bytiak, Ye.B. Radzishevska

“…Chronic pancreatitis (CP) is a complex progressive disease of the pancreas, which is accompanied by significant metabolic disorders, exocrine insufficiency, maldigestion, and malabsorption. …”
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A hybrid optimization algorithm based on cascaded (1 + PI)-PI-PID controller for load frequency control in interconnected power systems by Md. Shahid Iqbal, Md. Faiyaj Ahmed Limon, Md. Monirul Kabir, Md. Zakir Hossain, Md. Fahad Jubayer, Md. Janibul Alam Soeb

“…This study introduces a cascaded (1+PI)-PI-PID controller optimized using the improved Artificial Bee Colony-Particle Swarm Optimization (IABC-PSO) algorithm for LFC in interconnected power systems, aiming to address complex challenges associated with LFC in modern power systems. …”
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Frequency-comb-referenced multiwavelength interferometry for high-precision and high-speed 3D measurement in heterogeneous semiconductor packaging by Park Jun Hyung, Kim Dae Hee, Chu Huy Hoang, Hahm Ji Won, Kang Guseon, Lee Dongil, Song Seyong, Kang Mingu, Kim Seung-Woo, Kim Young-Jin

“…As 2.5D/3D packaging architectures become increasingly complex, our approach will readily meet the critical industrial demands for high-precision and high-speed measurement of multiscale features in advanced semiconductor packaging.…”
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Virtual care for prostate cancer survivorship: protocol for an evaluation of a nurse-led algorithm-enhanced virtual clinic implemented at five cancer centres across Canada by Antonio Finelli, Ricardo Rendon, Joseph A Cafazzo, Robert Hamilton, Alejando Berlin, Jacqueline L Bender, Denise Bryant-Lukosius, Quynh Pham, Jason Hearn, Ian Brown, Andrew H Feifer, Geoffrey Gotto

“…Current models of survivorship care are no longer adequate to address the chronic and complex survivorship needs of patients today. Virtual care models for cancer survivorship have recently been associated with comparable clinical outcomes and lower costs to traditional follow-up care, with patients favouring off-site and on-demand visits. …”
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Novel Benzenesulfonamide Derivatives of 5′-Aminospirotriazolotriazine Exhibit Anti-Inflammatory Activity by Suppressing Pro-Inflammatory Mediators: In Vitro and In Vivo Evaluation... by Amany M. Hamed, Souhaila S. Enaili, Walaa I. Mohammed, Azza M. A. Abouelella, Zeyad Elsayed Eldeeb Mohana, Dina M. Monir, Safaa S. Soliman, Elsayed Eldeeb Mehana Hamouda, Hytham Mahmoud Abd Elatif, Ahmed M. El-Saghier

“…<b>Background/Objectives</b>: Inflammation is a crucial and complex mechanism that protects the body against infections. …”
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Perioperative management of adult patients undergoing coronary artery bypass grafting and valve surgery: a literature review by Nair Naiara Barros de Vasconcelos, Veronica Neves Fialho Queiroz, Guilherme Martins de Souza, Sandrigo Mangini, Fernando Morita Fernandes Silva, Luiz Guilherme Villares da Costa, Pedro Paulo Zanella do Amaral Campos, Samuel Padovani Steffen, Flávio Takaoka, Ary Serpa Neto, Adriano José Pereira, Carmen Silvia Valente Barbas, Thiago Domingos Corrêa, Renato Carneiro de Freitas Chaves

“…The perioperative management of patients undergoing coronary artery bypass grafting, percutaneous coronary intervention, and heart valve surgery is highly complex and involves numerous specific conditions. …”
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Classification of SERS spectra for agrochemical detection using a neural network with engineered features by Mateo Frausto-Avila, Monserrat Ochoa-Elias, Jose Pablo Manriquez-Amavizca, María del Carmen González-López, Gonzalo Ramírez-García, Mario Alan Quiroz-Juárez

“…Compared to other machine-learning algorithms, our approach offers reduced computational complexity while maintaining or exceeding the accuracy of more complex models. …”
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Optimized AI and IoT-Driven Framework for Intelligent Water Resource Management by Mahmoud Badee Rokaya Mahmoud, Dalia Ismaeil Ibrahim Hemdan, Samah Hazzaa Alajmani, Raneem Yousif Alyami, Ghada Elmarhomy, Hassan Hashim, El-Sayed Atlam

“…However, water leak detection and irrigation scheduling traditional AI models are often computationally intensive and require complex hyperparameter tuning, making them less scalable. …”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…Engaging caregivers as partners is critical to ensure interventions align with their needs and priorities.…”
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Transcriptome and yeast two-hybrid sequencing shed light on the crosstalk between light and jasmonate signaling in regulating tanshinone biosynthesis by Han Zheng, Xueqing Fu, Muyao Yu, Qi Liu, Chenyi Li, Ling Li, Shuyi Qian, Kang Chen, Shuncang Zhang, Kexuan Tang, Luqi Huang

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Taking the pulse of nature – how robotics and sensors assist in lake and reservoir management by S. Zug, G. Licht, E. Börner, E. de Souza Mota, R. Monteiro Bezerra de Lima, R. Monteiro Bezerra de Lima, E. Roeder, J. Matschullat, J. Matschullat

“…</p> <p>This paper outlines the design criteria, engineering challenges, and solutions implemented to ensure reliable, autonomous operation. The platform supports modular catamaran floaters sized between 1.2 and 2.5 m, selected according to payload mass and mission requirements. …”
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Variability in Survival Outcomes Among Asian Ethnic Groups with Stage IV NSCLC by Aria Bassiri, Yue-Lin Hu, Christina Boutros, Boxiang Jiang, Jillian Sinopoli, Leonidas Tapias Vargas, Philip A. Linden, Christopher W. Towe

“…Cancer outcomes result from a complex interplay of genetics, environment, and socioeconomic factors. …”
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InsNet-CRAFTY v1.0: integrating institutional network dynamics powered by large language models with land use change simulation by Y. Zeng, C. Brown, C. Brown, M. Byari, J. Raymond, T. Schmitt, M. Rounsevell, M. Rounsevell, M. Rounsevell

“…While LLM agents demonstrate high flexibility and autonomy in modelling human decision-making and institutional dynamics, their integration with existing land use models is complex, requiring careful workflow design to ensure reliability. …”
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Optimizing cadaveric models for endovascular training through effective preparation techniques by Christopher Ibarra, MD, Alex D. Contreras, MS, Samantha Cervantes, MS, Rebecca Barnes, MBS, Stuart J. Corr, PhD, Alan B. Lumsden, MD, Maham Rahimi, MD

“…The study enhances the model’s capability to support complex procedures, emphasizing its practical application in advanced training. …”
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A Mindfulness-Based App Intervention for Pregnant Women: Qualitative Evaluation of a Prototype Using Multiple Case Studies by Silvia Rizzi, Maria Chiara Pavesi, Alessia Moser, Francesca Paolazzi, Michele Marchesoni, Stefania Poggianella, Erik Gadotti, Stefano Forti

“… BackgroundPregnancy is a complex period characterized by significant transformations. …”
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Challenging assumptions: a tripartite assessment of medical quality, resource utilization, and equity concerns in pediatric telemedicine by Motti Haimi, Ruslan Sergienko, Tzipi Hornik-Lurie, Dov Albukrek

“…These associations may reflect complex interactions between patient characteristics, provider behavior, and care modalities that warrant further investigation. …”
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The Use of Neural Networks in Distance Education Technologies for the Identification of Students by O. A. Kozlova, A. A. Protasova

“…The identification procedure must be repeated several times during a session to ensure that the identity of the authorized user is verified.Conclusion. …”
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Social health insurance, family support, and chronic diseases as determinants of health service utilization among senior citizens in rural Nepal by Sujan Poudel, Anusha Parajuli, Nirmal Duwadi, Bal Krishna Bhatta, Shishir Paudel, Dhurba Khatri, Damaru Prasad Paneru, Yam Prasad Sharma

“…Abstract Background The increasing trend of senior citizens and their complex healthcare needs demands the improvised provision of healthcare services and strategies to improve health service utilization to ensure health for all. …”
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