Functional circuits of LYL1 controlled by supraphysiological androgen in prostate cancer cells to regulate cell senescence by Mehdi Heidari Horestani, Katrin Schindler, Aria Baniahmad

“…The androgen receptor (AR) regulates the development and physiological function of normal prostate as well as the proliferation of cancerous prostate tissue. …”
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Surface functionalization of cellulose nanocrystals derived from waste newspaper for highly efficient Mn (VII) sorption by F. M. Mohamed, Mohamed R. El-Aassar, B. Y. Eweida, A. M. Abdullah, H. A. Hamad, M. F. Alrakshy, Mohamed. Abdel Rafea, R. E. Khalifa

“…Abstract This study aims to produce functionalized cellulose nanocrystals (FCNCs) by preparing and functionalizing cellulose nanocrystals (CNCs) from eco-friendly newspapers utilizing a straightforward two-step reaction with an anionic polymer (poly hydrex 6161). …”
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Brain structure and function differences across varying levels of endurance training: a cross-sectional study by Keying Zhang, Chunmei Cao, Yaxue Wang, Dong Zhang

“…High-level endurance athletes exhibit pronounced enhancements in gray matter volume and functional activity in regions associated with memory, motor control, and sensory processing. …”
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Electron-phonon interactions and Helmholtz free energy in confined systems: Advancing low-dimensional superconductors for quantum technologies by Nitin Pratap Singh, Kusum Lata, Linga Reddy Cenkeramaddi

“…The analysis also encompasses the behavior of electron–phonon interactions in quantum wells, offering insights into energy confinement and the effects of temperatures. …”
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Hydrosilane‐Functionalized [2.2]Paracyclophane for Plasma‐Etch‐Resistant and Post‐Modifiable Poly(Para‐Xylylene) by Lukas Bichlmaier, Tetsuhiko F. Teshima, Arseni Kostenko, George Al Boustani, Rebecca Wilhelm, Sebastian Stigler, Shuma Tanaka, Hiroaki Onoe, Bernhard Wolfrum, Shigeyoshi Inoue

“…Abstract Poly(para‐xylylene)s (PPXs), or so‐called parylenes, have become a well‐established polymer class in the conformal coating industry. …”
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Lead Causes Lipid Droplet Accumulation by Impairing Lysosomal Function and Autophagic Flux in Testicular Sertoli Cells by Chengwei Guo, Lingqiao Wang, Ke Cui, Guowei Zhang, Yao Tan, Weiyan Chen, Yiqi Wang, Jijun Liu, Wenbin Liu, Guanghui Zhang, Ziyuan Zhou

“…Thus far, the underlying molecular mechanisms of Pb-induced reproductive toxicity are still not well understood. In this study, 64 male ICR mice were given drinking water with Pb (0, 100, 200, and 300 mg/L) for 90 days. …”
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Exposure to polycyclic aromatic hydrocarbons and risk of abnormal liver function: The mediating role of C-reactive protein by Yating Wang, Enwei Zhu, Xiaoyan Zhu, Xiaoliang Li, Mei’an He, Rihong Zhai, Xuli Wu, Dongsheng Hu, Xu Han

“…Furthermore, mediation analysis indicated that plasma CRP mediated 13.4 % of the association between 1-OH-PYR and ALF risk. These results enhanced our comprehension of the health effects of PAHs exposure on liver function as well as the underlying mechanism.…”
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CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life

“…SF-36 scores improved from 20.28 to 47.35 (hip) and from 17.36 to 43.00 (knee), highlighting a considerable enhancement in overall well-being. Functional recovery was confirmed by KSS improvement (from 33.7/100 to 82.8/100) and by gains in ROM: +60° in hips and +30° in knees. …”
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Emerging role of the cGAS-STING pathway in cardiovascular diseases: biologic function, mechanisms and targeted therapy by Junke Mou, Yuwu Chen, Xinxin Zhu, Biyi Xu, Mengyang Wang, Jiani Xie, Tong Lin, Qishuo Gu, Qiuwen Wu, Ziao Che, Ji Li, Xing Luo, Haibo Jia, Bo Yu

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Comparative and Functional Analysis of Exosomal microRNAs During Semelparous Reproduction in Ayu Fish (Plecoglossus altivelis) by Yida Pan, Lingxin Meng, Kazuma Yoshida, Liangjie Qiu, Taichi Ito, Ryo Yonezawa, Kazutoshi Yoshitake, Shunsuke Saito, Nahoko Bailey‐Kobayashi, Tetsuhiko Yoshida, Shiheharu Kinoshita, Shuichi Asakawa

“…Furthermore, it was observed that key cellular processes and signalling pathways associated with intercellular transmission and intracellular stress are regulated by miRNA expression, and these changes in regulation may be responsible for post‐breeding mortality. This study enhances our understanding of the function of exosomal miRNA during semelparous reproduction in ayu fish and provides further insight into the intrinsic mechanisms of ageing and mortality in organisms.…”
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Current situation of pharmacy services in community health centers and the functioning of pharmacists in family doctor teams in Shanghai by Rui LIU, Yu CAO, Aiqun CHU, Huanyun WU

“…Pharmacy services, facilitated by community health centers with regional advantages, align with their functional orientation. However, a significant gap persists between the supply of pharmacy services in community health centers and public demand. …”
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Catheter Ablation of Frequent PVCs in Structural Heart Disease: Impact on Left Ventricular Function and Clinical Outcomes by Nikias Milaras, Nikolaos Ktenopoulos, Paschalis Karakasis, Aikaterini-Eleftheria Karanikola, Vasileios Michopoulos, Konstantinos Pamporis, Panagiotis Dourvas, Anastasios Apostolos, Zoi Sotiriou, Stefanos Archontakis, Athanasios Kordalis, Konstantinos Gatzoulis, Skevos Sideris

“…In non-ischemic cardiomyopathy, successful ablation improved LVEF by 8–12% on average and enhanced NYHA class. Across mixed cohorts, patients with sustained PVC suppression showed significant improvements in LVEF, functional status, which, in many cases, removed the indication for implantable cardioverter-defibrillators. …”
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Task-oriented telerehabilitation for upper limb functional recovery after stroke: a retrospective cohort study by Xiaojuan Hong, Huanghong Cha, Xiao Bao, Jinning Luo, Xiuling Li, Jinling Cheng, Zicai Liu

“…The 95% CI for FMA-UE improvement between Tele-rehab TOT and face-to-face TOT was [−0.81, 7.39], not exceeding the non-inferiority margin of 12.4.ConclusionTask-oriented training and remote traditional neurofacilitation techniques for tele-rehabilitation of stroke patients can enhance upper limb motor function and improve quality of daily life with comparable efficacy to face-to-face task-oriented training. …”
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RETRACTED: ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14 by Danfeng Guo, Danfeng Guo, Danfeng Guo, Xiaodan Zhang, Xiaodan Zhang, Xiaodan Zhang, Honglei Cui, Honglei Cui, Honglei Cui, Dongsheng Yu, Dongsheng Yu, Dongsheng Yu, Huapeng Zhang, Huapeng Zhang, Huapeng Zhang, Xiaoyi Shi, Xiaoyi Shi, Xiaoyi Shi, Chun Pang, Chun Pang, Chun Pang, Jie Li, Jie Li, Jie Li, Wenzhi Guo, Wenzhi Guo, Wenzhi Guo, Shuijun Zhang, Shuijun Zhang, Shuijun Zhang

“…ACADL, a mitochondrial enzyme that facilitates the primary regulated step in mitochondrial fatty acid oxidation, plays a role in HCC growth inhibition. However, the function of ACADL in tumor metastasis is not well elucidated. …”
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Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population by Zhanyi Yang, Jiaai Xu, Xiaoyu Yang, Pengcheng Yi, Jian Ruan, Yingying Wu, Yushan Li, Geng Tian, Fuyi Xu, Jia Mi, He Li, Chunhua Yang

“…In hepatocytes, MORC4 knockdown significantly elevated total TC/TG levels, as well as enhanced lipid accumulation. Whereas MORC4 overexpression restored total TC/TG levels, along with lipid accumulation in knockdown cell lines. …”
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Antioxidant, Physiochemical, and Sensory Properties of Functional Marshmallow Produced from Honey, Strawberry Concentrates, and Hibiscus Extract by Maher M. Al-Dabbas, Etaf G. Abu Samaan, Sehar Iqbal, Hani J. Hamad, Rawan Al-Jaloudi, Mohammad Shahein, Bha’a Aldin Al-Nawasrah, Abdalrahman Al-Zabt, Doa`a Al-Refaie, Nisreen Shehadeh, Mahmoud Abughoush

“…Overall, this study shows that the use of functional ingredients significantly enhanced the total phenolic and flavonoid content and improved antioxidant activities in marshmallow production. …”
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Optimizing shrimp nutrition and health: ginseng saponins as functional additives in low-fishmeal diets on Litopenaeus vannamei by Sihan Lin, Rong Yao, Xin Cui, Yucai Guo, Denghui Hu, Bin Zhou, Zhaobin Zhou, Xuanshu He, Zhihong Liao, Beiping Tan, Jin Niu

“…These findings imply that in addition to improving growth performance, adding ginseng saponins at a concentration of 11% fishmeal could improve the antioxidant capacity of L. vannamei as well as its resistance to stress. Therefore, ginseng saponins can be utilized as a functional additive to increase L. vannamei growth performance, enhance antioxidant capacity, and reduce stress in low-fishmeal diets, 0.3% of ginseng saponins is optimal.…”
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EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6 by Anna-Christina Eilers, Ruari Mackenzie, Elia Pizzati, Jorryt Matthee, Joseph F. Hennawi, Haowen Zhang, Rongmon Bordoloi, Daichi Kashino, Simon J. Lilly, Rohan P. Naidu, Robert A. Simcoe, Minghao Yue, Carlos S. Frenk, John C. Helly, Matthieu Schaller, Joop Schaye

“…By measuring the two-point cross-correlation function of quasars and their surrounding galaxies, as well as the galaxy autocorrelation function, we infer a correlation length of quasars at 〈 z 〉 = 6.25 of ${r}_{0}^{\mathrm{QQ}}={22.0}_{-2.9}^{+3.0}\,\mathrm{cMpc}\,{h}^{-1}$ , while we obtain a correlation length of the [O iii ]-emitting galaxies of ${r}_{0}^{\mathrm{GG}}=4.1\,\pm 0.3\,\mathrm{cMpc}\,{h}^{-1}$ . …”
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The Multifaceted Effects of Ashwagandha (Withania somnifera) Root Extract on Physical Performance, Cognitive Function, Mental Health, and Safety in Adults by Natalia Zakrzewska, Mateusz Bychowski, Julia Kwaśna, Adrianna Załęska, Izabela Kaźmierczyk, Kacper Lenart, Mateusz Górski, Michał Homza, Szymon Bednarek, Joanna Kulicka

“… Background: Ashwagandha root extract offers broad therapeutic benefits, enhancing physical performance, mental health, and cognitive function, making it a valuable adaptogenic and nootropic solution. …”
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Maternal zinc alleviates tert-butyl hydroperoxide-induced mitochondrial oxidative stress on embryonic development involving the activation of Nrf2/PGC-1α pathway by Liang Huang, Wei Gao, Xuri He, Tong Yuan, Huaqi Zhang, Xiufen Zhang, Wenxuan Zheng, Qilin Wu, Ju Liu, Wence Wang, Lin Yang, Yongwen Zhu

“…In vivo and in vitro studies revealed that Zn addition enhances (P < 0.05) ATP synthesis and metallothionein 4 (MT4) content and expression as well as alleviates (P < 0.05) the BHP-induced mitochondrial ROS generation, oxidative damage and dysfunction, exerting a protective effect on mitochondrial function by enhancing antioxidant capacity and upregulating the mRNA and protein expressions of Nrf2 and PGC-1α. …”
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