Additively manufactured hybrid auxetic structures for enhanced low frequency acoustic performance through experiments and modelling by Ali Bin Naveed, Aamir Mubashar, Muhammad Khizer Ali Khan, Adnan Munir, Kamran A. Khan

“…Results indicate substantial enhancement in SAC as well as STL from baseline design of the same dimensions. …”
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Rational Design for Simultaneous Enhancement of Thermal Stability and Catalytic Activity of β-Mannanase from Aspergillus niger by ZHOU Jie, ZHU Yanbing, WANG Xinghua, LI Lijun, JIANG Zedong, NI Hui

“…These findings provide a useful strategy for improving the thermal stability and activity of β-mannanase from A. niger, and promote understanding of the relationship between β-mannanase structure and function, as well as the industrial application of the enzyme.…”
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Enhancement of the operating time of the overcurrent relay of the distribution network with high-level penetration of renewable energy sources by Mahmoud Aref, Mahmoud A. Mossa, Emad Abdelkarim, Khairy Sayed, Mishari Metab Almalki, Alaa F.M. Ali

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Effects of Low-molecular-weight Glycyrrhiza Polysaccharides on Immune Function, Gut Microbiota and Metabolites in Healthy Mice by Shengnan XUE, Wangdi SONG, Yunyun WANG, Yan ZHANG, Genlin ZHANG

“…Conclusion: Low-molecular-weight Glycyrrhiza polysaccharide achieved probiotic effects by enhancing the intestinal barrier function, tissue antioxidant capacity and immune response of healthy organisms, as well as changing the structure of gut microbiota and the types of metabolites.…”
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Expression of SIRPα-Fc by oncolytic virus enhances antitumor efficacy through tumor microenvironment reprogramming by Qingzhe Yang, Yongheng Shu, Yanwei Chen, Zhongbing Qi, Shichuan Hu, Yao Zhang, Yu Qin, Xianglin Xu, Jianchuan Hu, Anliang Huang, Ping Cheng

“…Additionally, while both oAdVs increased T cell infiltration in the tumor microenvironment, oAd-SA specifically enhanced T cell immune function. The study also revealed that oAdVs modulate TAMs differently across tumor types, with oAd-SA therapy particularly increasing TAM phagocytosis and promoting an anti-tumor response.…”
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Royal Jelly Enhances the Social Status of Submissive Rats by Restoring Balance to the Disturbed Gut–Brain Communication by Feng Zhu, Jinchun Xu, Tian Wang, Ruili Yang, Biao He, Hui-Li Wang, Yi Xu

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Cortical Actin Depolymerisation in 3D Cell Culture Enhances Extracellular Vesicle Secretion and Therapeutic Effects by Zhen Yang, Xiaoke Li, Qiyuan Lin, Fanfan Zhou, Kaini Liang, Jiao Jiao Li, Yudi Niu, Qingchen Meng, Tianyuan Zhao, Hao Li, Du Wang, Jianjing Lin, Hui Li, Bin Wang, Wei Liu, Yanan Du, Jianhao Lin, Dan Xing

“…In addition, sEVs derived from 3D cultured MSCs demonstrated enhanced therapeutic function both in vitro and in rat models of osteoarthritis (OA) and wound healing. …”
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IA-CIOU: An Improved IOU Bounding Box Loss Function for SAR Ship Target Detection Methods by Pingping Huang, Shihao Tian, Yun Su, Weixian Tan, Yifan Dong, Wei Xu

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Semaphorin4B is elevated in rheumatoid arthritis and enhances the inflammatory phenotype of macrophages and fibroblast-like synoviocytes by Sara Martínez-Ramos, Carlos Rafael-Vidal, Jaime Marty, Beatriz Malvar-Fernández, Coral Mouriño, Nair Pérez, Irene Altabás, Francisco J. Maceiras Pan, David Fernández-Fernández, Carmen Conde, Megan M. Hanlon, Conor M. Smith, Paul Peter Tak, Douglas J. Veale, Ursula Fearon, Jose María Pego-Reigosa, Samuel García

“…Functionally, Sema4B alone induced FLS migration and invasion, and enhanced the TNF-α or LPS-induced production of inflammatory mediators (Interleukin (IL)-6, IL-8, TNF-α, CCL-2) and matrix metalloproteases (MMP-1 and MMP-3) in RA FLS, RA MØ and the 3D synovium model. …”
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Curcumin Combined with Aerobic Exercise Improved Liver Function in Rats with Non-alcoholic Fatty Liver Disease by HU Ge, QIN Fei, CAO Jianmin, JI Zhe, ZHOU Qiyun, ZHOU Haitao

“…Conclusion: Curcumin and/or aerobic exercise intervention could improve liver structure and function in NAFLD rats by moderately enhancing cellular autophagy through the regulation of the AMPK/mTOR signaling pathway. …”
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Enhanced cell sheet engineering through combination of single cells and spheroids on liquid interface using perfluorocarbon by Ji Hye Park, Ji-Seok Han, Eun-Jung Ann, Cho Yeon Kim, Byoung-seok Lee, Ji Su Kang, Sun-Sook Song, Junhee Lee, Sun-Woong Kang

“…Using single cells, spheroids, and their combination, we evaluated methods to enhance sheet formation. Single cells formed cohesive sheets at high densities (4 × 10 6 cells/well) but exhibited limited long-term stability due to nutrient constraints. …”
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Enhancing Balance, Strength, Flexibility and Spatiotemporal Gait Parameters in Pediatric Cerebral Palsy: Treadmill Training at Variable Inclinations by Neşe Toktaş, Hande Şenol, Mustafa Hapak, Ahmet Alptekin, Berna Ramanlı

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The dual-function of HSP70 in immune response and tumor immunity: from molecular regulation to therapeutic innovations by Beining Zhang, Ruiqun Qi, Ruiqun Qi

“…This review aims to systematically analyze the immune regulatory functions of HSP70, focusing on its dual regulatory mechanisms and the “double-edged sword” nature of HSP70 in tumor immunotherapy and the innovative nature of targeted strategies, as well as providing a theoretical basis and research directions for precision medicine in the treatment strategies of related diseases.…”
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The Effectiveness of Unified Protocols for Transdiagnostic Treatment on Detective Thinking and Reflective Functioning of Children with Type 1 Diabetes by Maryam Hashemipoor Zavareh, Mansoureh Bahramipour Isfahani, Ilnaz Sajjadian

“…Conclusions: Integrated transdiagnostic therapy demonstrated effectiveness in improving detective thinking and reflective functioning in children diagnosed with T1D. Notably, these positive effects were sustained beyond the intervention period, indicating the treatment’s potential as an efficient intervention strategy to enhance the psychological well-being of children with T1D.…”
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Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence Requirement by Maria Pavlaki, Stanley Zucker, Antoine Dufour, Nikki Calabrese, Wadie Bahou, Jian Cao

“…Cotransfection with furin cDNA also enhanced MMP-28 induced cell migration. In conclusion, our data provide a novel mechanism for MMP-28 function in cells in which furin serves as an intermolecular chaperone.…”
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Internally hollow Cu2O nanoframes with the abundance of {110} facets enhance direct propylene epoxidation by Yueming Qiu, Yichen Zhang, Ronghui Zhang, Meng Huang, Kok Bing Tan, Guowu Zhan, Gang Fu, Qingbiao Li, Jiale Huang

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IGF2BP2: an m6A reader that affects cellular function and disease progression by Siyi Liu, Shan Liao, Junyu He, Yanhong Zhou, Qian He

“…Abstract Insulin-like growth factor 2 messenger RNA (mRNA)-binding protein 2 (IGF2BP2) is a widely studied N6-methyladenosine (m6A) modification reader, primarily functioning to recognize and bind to m6A modification sites on the mRNA of downstream target genes, thereby enhancing their stability. …”
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Microplastics as Emerging Contaminants and Human Health: Exploring Functional Nutrition in Gastric–Colon–Brain Axis Cancer by Maria Scuto, Cinzia Maria Grazia Lombardo, Bruna Lo Sasso, Eleonora Di Fatta, Raffaele Ferri, Angela Trovato Salinaro

“…Furthermore, it highlights the role of functional nutrition and bioactive flavonoids—including chlorogenic acid, coumaric acid, and naringin—as well as the use of highly bioavailable combined polyphenol nanoparticles as potential detoxifying agents. …”
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Natural Polymer-Based Coatings for Animal-Derived Products: A Review of Applications, Functionality, Characterization, and Challenges by Márcio Vargas-Ramella, Noemí Echegaray, Paulo Cezar Bastianello Campagnol, José Manuel Lorenzo

“…These coatings act as physical barriers and can carry bioactive compounds, enhancing oxidative and microbial stability. Particular attention is placed on the structure-function relationships of biopolymers, their characterization through advanced techniques (e.g., Fourier Transform Infrared spectroscopy—FTIR, Scanning Electron Microscope—SEM, Differential Scanning Calorimetry—DSC, and Thermogravimetric analysis—TGA), and their functional properties (e.g., antimicrobial and antioxidant efficacy). …”
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Bioactive compounds, functional properties, health benefits, and food applications of black rice: a comprehensive review by Sagarika Das, Tapasya Kumari, Sai Babu, Nickhil C, Santosh Kumar, Sankar Chandra Deka

“…Black rice (Oryza sativa L.) also called ''emperor's rice'' or ''forbidden rice,'' is a nutrient-rich grain distinguished by its unique deep pigmentation and health-enhancing properties. Black rice is approximately six times richer in antioxidants compared to other rice varieties, and its bioactive components play a vital role in improving health and promoting well-being. …”
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