Nicotinamide mononucleotide boosts the development of bovine oocyte by enhancing mitochondrial function and reducing chromosome lagging by Shu Hashimoto, Udayanga Gamage, Yuki Inoue, Hisataka Iwata, Yoshiharu Morimoto

“…These results suggest that increased NAD(H) levels in oocytes following NMN treatment enhances post-fertilization developmental competence through improved mitochondrial function.…”
Get full text

Immuno-enhancing effects of surimi products including functional ingredients in vitro and in vivo zebrafish model by Dong-Hyeon Kim, Heeseob Lee, Hye-Won Yang, You-Jin Jeon

“…Our results suggested that FSPs with combination of A. vera gel powder and Red ginseng extract can induce the synergistic effect in immunity enhancement. In conclusion, FSPs could be applied to health functional seafood industries, in particular eomook markets with immune-enhancement. …”
Get full text

An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function by Ashley R. Brown, Ashley R. Brown, Grant A. Fox, Grant A. Fox, Irene M. Kaplow, Irene M. Kaplow, Irene M. Kaplow, Alyssa J. Lawler, Alyssa J. Lawler, BaDoi N. Phan, BaDoi N. Phan, BaDoi N. Phan, Lahari Gadey, Lahari Gadey, Morgan E. Wirthlin, Morgan E. Wirthlin, Easwaran Ramamurthy, Easwaran Ramamurthy, Gemma E. May, Ziheng Chen, Qiao Su, Qiao Su, C. Joel McManus, Robert van de Weerd, Robert van de Weerd, Andreas R. Pfenning, Andreas R. Pfenning, Andreas R. Pfenning

“…Here, we introduce a systemic MPRA (sysMPRA) to address these challenges through systemic intravenous AAV viral delivery.Results: We demonstrate successful transduction of the MPRA library into diverse mouse tissues, efficiently identifying tissue specificity in candidate enhancers and aligning well with predictions from machine learning models. …”
Get full text

The Relationship Between Sports YouTube Engagement, Psychosocial Functions of Sport, and Well-Being: Moderating Effect of Kinesiology and Non-Kinesiology University Students by Youngtaek Oh

“…Our findings demonstrated that engagement in sports YouTube engagement had a significant positive effect on both well-being and psychosocial functions of sport. Furthermore, psychosocial functions of sport had a significant positive effect on well-being. …”
Get full text

Enhancement of Asphalt Resilience through Functionalization of Natural Rubber with Glycidyl Methacrylate, Maleic Anhydride, and Divinylbenzene by Nanang Rahmat Wijaya, Tamrin, Eddiyanto, Joddy Arya Laksmono, Ahmad Hafizullah Ritonga

“…An effective solution is the modification of Asphalt using functionalized natural rubber (NR). Therefore, this research aimed to enhance Asphalt resilience by using NR functionalized with Glycidyl Methacrylate (GMA), Maleic Anhydride (MA), and Divinylbenzene (DVB), as well as to understand the interactions between the materials. …”
Get full text

Enhanced porcine gut barrier functioning and reduced inflammation from a combination of seaweed  bioactives by Meike A. Bouwhuis, Irene H. G. Nooijen, Evita van de Steeg, Shane O’Connell

Get full text

Verification and validation of zero-point electron-phonon renormalization of the bandgap, mass enhancement, and spectral functions by Samuel Poncé, Jae-Mo Lihm, Cheol-Hwan Park

“…We compare four first-principles codes: ABINIT, Quantum ESPRESSO, EPW, ZG, and three methods: (i) the Allen-Heine-Cardona theory using density functional perturbation theory (DFPT), (ii) the Allen-Heine-Cardona theory using Wannier function perturbation theory (WFPT), and (iii) an adiabatic non-perturbative frozen-phonon method. …”
Get full text

Coacting enhancers can have complementary functions within gene regulatory networks and promote canalization. by Leslie Dunipace, Zsuzsa Ákos, Angelike Stathopoulos

“…Developmental genes are often regulated by multiple enhancers exhibiting similar spatiotemporal outputs, which are generally considered redundantly acting though few have been studied functionally. …”
Get full text

Microbial Fermentation in Food: Impact on Functional Properties and Nutritional Enhancement—A Review of Recent Developments by Shailesh S. Sawant, Hye-Young Park, Eun-Young Sim, Hong-Sik Kim, Hye-Sun Choi

“…The escalating global demand for nutritious and sustainable food sources has heightened interest in microbial biotransformation in food, a process in which microorganisms chemically modify food components to enhance their functional properties and nutritional content. …”
Get full text

SuperEdgeGO: Edge-supervised graph representation learning for enhanced protein function prediction. by Shugang Zhang, Yuntong Li, Wenjian Ma, Qing Cai, Jing Qin, Xiangpeng Bi, Huasen Jiang, Xiaoyu Huang, Zhiqiang Wei

“…To date, there have been over 200 million known proteins, but only 0.2% of them have well-annotated functional terms. By measuring the contacts among residues, proteins can be described as graphs so that the graph leaning approaches can be applied to learn protein representations. …”
Get full text

Electroacupuncture Modulates Microbial Phenylalanine Metabolism and Enhances the Intestinal Barrier Function to Alleviate Colitis in Mice by Zhu L, Au R, Dai L, Li Y, Xu F, Cui Y, Hu J, Shen H

“…EA at ST36 enhanced the intestinal barrier by upregulating the expression of MUC2 and ZO-1. …”
Get full text

Preconditioning with an enriched environment enhances neuroplasticity and functional recovery following cerebral ischemia-reperfusion injury by Yi Zhang, Wen Liu, Lingling Liu, Yang Liu, Youqing Yang, Zhijie Yang, Xiuping Chen

“…These molecular changes were positively correlated with functional recovery in the MCAO model. Conclusions: Pre-ischemic exposure to an enriched environment may enhance neuroplasticity and support functional recovery following cerebral I/R injury, potentially through the upregulation of neuroplasticity-associated proteins and neurotrophic factors. …”
Get full text

POSSIBILITIES OF ENHANCED EXTERNAL COUNTERPULSATION USING IN CLINICAL PRACTICE by Z. A. Mamieva, A. S. Lishuta, Yu. N. Belenkov, E. V. Privalova, A. O. Yusupova, S. M. Rykova

“…Possibilities and prospects for the clinical use of enhanced external counterpulsation (EECP), which has long established itself throughout the world, are discussed in the article. …”
Get full text

Leveraging BiLSTM-CRF and adversarial training for sentiment analysis in nature-based digital interventions: Enhancing mental well-being through MOOC platforms by Juanjuan Zang

“…This study contributes to the growing body of research on digital mental health interventions within natural settings, providing valuable insights into how technology can support and enhance mental well-being in these contexts.…”
Get full text

Yeast peptides alleviate diarrhea in neonatal lambs by enhancing the colonic barrier function and modulating colonic microbiota by Dingkun Fan, Rui Zong, Rui Zong, Chengrui Zhang, Jixian Zhang, Jianmin Chai, Jianmin Chai, Kai Cui, Naifeng Zhang

“…Furthermore, yeast peptides enhanced intestinal antioxidant capacity and ultimately strengthened colonic barrier function (p < 0.05). …”
Get full text

Advancements in green extraction technologies for pectin enhancing efficiency, sustainability, and functional properties: a systematic review by R. J. Mapartida Yapias, F. Ore Areche, J. P. Echevarria Victorio, J. Paucarchuco Soto, G. R. Lobato Calderon, E. R. Palomino Santos, J. M. Montalvo Otivo, C. Flores-Miranda, A. Ruiz Rodriguez

“…These methods present advantages such as higher extraction performance with lowered energy usage as well as better pectin rheological properties that enhance both gel strength and viscosity. …”
Get full text

Obesity and hyperlipidemia were associated with more severe synovitis and structural abnormalities as well as inferior functional outcomes in knee osteoarthritis: a retrospective c... by Kuo Hao, Juncai Wang, Yingzhen Niu, Fei Wang

“…There were significant associations of obesity or hyperlipidemia with all synovial inflammatory markers and cartilage, bone marrow edema, meniscus, and total WORMS scores as well as functional outcomes (P < 0.05). Conclusions Obesity and hyperlipidemia were associated with more severe synovitis and structural abnormalities of knee OA, as well as inferior preoperative and postoperative functional outcomes. …”
Get full text

PCPE2: Expression of multifunctional extracellular glycoprotein associated with diverse cellular functions by Michael J. Thomas, Hao Xu, Angela Wang, Mirza Ahmar Beg, Mary G. Sorci-Thomas

“…Due to the many similarities between the two related proteins, PCPE2 has been assumed to have biological functions similar to PCPE. PCPE is a well-established enhancer of procollagen processing activating the enzyme, BMP-1. …”
Get full text

Acorn Flour as A Functional Ingredient: Impacts on Health and Baking Properties in Wheat - Based Products by Sikora Fryderyk, Ochmian Ireneusz, Sobolewska Magdalena

“…The conclusions underscore acorn flour's potential as a functional ingredient that not only enhances bread's nutritional profile but also contributes to food sustainability.…”
Get full text

Radiomic analysis using T1 mapping in gadoxetic acid disodium-enhanced MRI for liver function assessment by Xin Li, Guangyong Ai, Xiaofeng Qiao, Weijuan Chen, Qianrui Fan, Yudong Wang, Xiaojing He, Tianwu Chen, Dajing Guo, YangYang Liu

Get full text