Overexpression of Rhizobium rhizogenes A4-rolB enhances osmotic stress resistance in Arabidopsis by Xuefei Chen, Bruno Trevenzoli Favero, Fulai Liu, Henrik Lütken

“…Abstract Background Functional investigation of individual Rhizobium rhizogenes oncogene contributes to a deeper understanding of the mechanisms underlying R. rhizogenes-plant transformation, which holds the potential of enhancing plants’ abiotic stress resistance. …”
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The Two Sides of Placebo Analgesia: Differential Functional Connectivity Reveals Mechanisms of Placebo Analgesic Response by Bush NJ, Cushnie AK, Boissoneault J, Aghabeigi S, Alexander C, Staud R, Robinson ME

“…Participants completed a baseline followed by a placebo session involving the application of an inactive cream in the context of an expectancy-enhancing instruction set while undergoing a functional magnetic resonance imaging scan (fMRI). …”
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Spectral wavelength range influences the performance of chemometric models estimating various foliar functional traits by Minjee Park, Lorenzo Cotrozzi, Geoffrey M. Williams, Matthew D. Ginzel, Michael V. Mickelbart, Douglass F. Jacobs, John J. Couture

“…This approach has considerable implications in advancing plant physiological and chemical ecology. For complex functional traits, however, there is a lack of well‐defined absorption features and features may be unevenly distributed across the reflectance spectrum, suggesting that the influence of wavelength ranges on the performance of chemometric models is potentially important for accurately estimating foliar functional traits. …”
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Functional characterization of COMT genes in Chinese white pear (Pyrus bretschneideri) and their role in lignin synthesis by Xiaofeng Feng, Xiaofeng Feng, Xianang Wu, Xianang Wu, Jiayi Hong, Jiayi Hong, Zihui Guo, Zihui Guo, Yasmin Khan, Yasmin Khan, Dongyi Wei, Dongyi Wei, Honghong Fan, Honghong Fan, Yongping Cai, Yongping Cai

“…In situ hybridization revealed that the expression of PbrCOMT1 coincides with lignin, highlighting its role in stone cell development. Functional studies, including transient transformation of pear and strawberry fruit, as well as stable transformation of Arabidopsis thaliana, demonstrated that PbrCOMT1 overexpression enhances lignin content, while gene silencing diminishes it. …”
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Enhanced THBS2 promotes collagen synthesis and inflammatory secretome of fibroblasts in idiopathic pulmonary fibrosis by Lu Yu, Rui Wang, Qinhui Hou, Fan Yang, Ying Liu, Meiting Peng, Yihan Dong, Yuan Liu, Zhenshun Cheng

“…Abstract The pathogenesis of pulmonary fibrosis involves structural remodeling and functional impairment of lung tissue, accompanied by increased secretion of pro-inflammatory mediators and abnormal synthesis of the extracellular matrix (ECM). …”
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Analysis of enhancer RNA LINC00910 expression correlating with the immunoregulator STAT3 in glioblastoma cells by E. M. Stasevich, A. V. Simonova, A. N. Uvarova, E. A. Zheremyan, K. V. Korneev, E. A. Bogomolova, D. E. Demin

“…Further studies using the selected interfering RNA will help to clarify the role of the enhancer RNA LINC00910 in other signallingsignaling pathways, as well as its potential relationship with cancer development.…”
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A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function by Alice Beau, Jane Natividad, Berengère Benoit, Philippe Delerive, Stéphane Duboux, Yuan Feng, Marie Jammes, Cecile Barnel, Giuseppina Sequino, Claudie Pinteur, Griet Glorieux, Denis Fouque, Hubert Vidal, Laetitia Koppe

“…The in vivo efficacy of SynCKD (and the synergic effect) was established in two uremic rodent models, demonstrating lower plasma levels of UTs and enhancing kidney function after 6–8 weeks of treatment. …”
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Overexpression of soybean SGF14a enhanced tolerance of transgenic tobacco plants to aluminum stress by Yang Zhili, Guo Chuanlong, Liu Lei, Wu Konghuan, Wang Lin, Li Kunzhi, Zhao Yan, Chen Limei

“…A lot of 14-3-3 gene family members are isolated in different plants. 14-3-3 proteins regulate various physiological activities and functions by interacting with phosphorylated or non-phosphorylated target proteins in plants. …”
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Prevalence of falls and associations with family functioning among community-dwelling older adults in Guangzhou, China by Si-Yu Sun, Zhi-Wei Wang, Zhi-Li Peng, Le-Xin Yuan, Wen-Hao Yang, Wen-Jian Zhang, Jia-Min Chen, Wei-Quan Lin, Wei Zhu, Wei Zhu

“…In addition, it was shown that a well-functioning family was a protective factor against falls [OR = 0.589, 95%CI (0.44–0.789)].ConclusionThe prevalence of falls among community-dwelling older adults in Guangzhou City was high, and the influencing factors were complex. …”
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Enhancing Early Detection of Diabetic Retinopathy Through the Integration of Deep Learning Models and Explainable Artificial Intelligence by Kazi Ahnaf Alavee, Mehedi Hasan, Abu Hasnayen Zillanee, Moin Mostakim, Jia Uddin, Eduardo Silva Alvarado, Isabel de la Torre Diez, Imran Ashraf, Md Abdus Samad

“…Such a disease can exists in human eye that can affect one or both eyes is diabetic retinopathy (DR) which can impair function, vision, and eventually result in permanent blindness. …”
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Social capital, functional health status and quality of life among adults in rural Southwest Nigeria by Promise Izuchukwu Okoroafor, Joshua Odunayo Akinyemi, Mobolaji Modinat Salawu, Olufunmilayo Ibitola Fawole

“…Abstract Background The health and well-being of adults is important for attainment of the third sustainable development goal. …”
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Aquaporin Channels in Skin Physiology and Aging Pathophysiology: Investigating Their Role in Skin Function and the Hallmarks of Aging by Nazli Karimi, Vahid Ahmadi

“…Key physiological features, such as elasticity and repair capability, are essential for its proper function. However, with aging, these characteristics deteriorate, reducing the skin’s ability to tolerate environmental stressors which contribute to external aging as well as internal aging processes, which negatively affect barrier function, immune response, and overall well-being. …”
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Enhancing Cross-Domain Remote Sensing Scene Classification by Multi-Source Subdomain Distribution Alignment Network by Yong Wang, Zhehao Shu, Yinzhi Feng, Rui Liu, Qiusheng Cao, Danping Li, Lei Wang

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Naps, night-time sleep and cognitive function among middle-aged and older people in China. by Xiuxiu Zhou, Yutang Tan, Di He, Hong Wu

“…<h4>Background</h4>There is increasing interest in how sleep affects cognitive function; however, the combined impact of naps and night-time sleep on different cognitive domains is still not well understood. …”
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Insights and progress on the biosynthesis, metabolism, and physiological functions of gamma-aminobutyric acid (GABA): a review by Qingli Zhang, Lei Zhu, Hailong Li, Qu Chen, Nan Li, Jiansheng Li, Zichu Zhao, Di Xiao, Tingting Tang, Chunhua Bi, Yan Zhang, Haili Zhang, Guizhen Zhang, Mingyang Li, Yanli Zhu, Jingjing Zhang, Jingjing Kong

“…In mammals, it influences physiological functions such as nervous system regulation, blood pressure equilibrium, liver and kidneys enhancement, hormone secretion regulation, immunity enhancement, cancer prevention, as well as anti-aging effects. …”
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The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus. by Kristin A Sauter, M Amine Bouhlel, Julie O'Neal, David P Sester, Hiromi Tagoh, Richard M Ingram, Clare Pridans, Constanze Bonifer, David A Hume

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Enhancing Damping in Single-Phase Grid-Forming Virtual Oscillator Control Inverters: A Feedforward Strategy by Hamed Rezazadeh, Mohammad Monfared, Meghdad Fazeli, Saeed Golestan

“…This article presents a novel technique to improve the dynamic response of single-phase VOC-based inverters by enhancing damping without affecting the virtual inertia and droop functionalities. …”
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An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation by Sagar Khavnekar, William Wan

“…This uses all the data in each image to enhance the visibility of Thon rings, thereby improving high‐resolution CTF estimation and subsequent enhancements in the resolution of subtomogram averages.…”
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Key biochemical pathways during pregnancy in livestock: mechanisms regulating uterine and placental development and function by Katherine M Halloran, Claire Stenhouse

“…Several metabolic pathways play critical roles in uterine and placental function during pregnancy by supporting processes important for cellular function and proliferation, as well as conceptus growth and development. …”
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The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions by Hyeji Jung, Byeongchan Kim, Gyubin Jang, Hyeonho Kim, Ae-Ree Lee, Sung-Hyun Yoon, Kyung-Seo Lee, Gaeun Hyun, Younghye Kim, Jaewon Ko, Je-Wook Yu, Ji Won Um

“…Here, using NLRP3 (NOD-like receptor family, pyrin domain-containing protein 3) conditional knockin (cKI) mice harboring a D301N point mutation originating in patients with autoinflammatory diseases, we found that activation of the NLRP3 inflammasome by administration of lipopolysaccharide induced anxiety-like and repetitive behaviors frequently found in patients with neuropsychiatric disorders, as well as increasing NMDAR (N-methyl-D-aspartate receptor)-mediated excitatory synaptic functions in the medial prefrontal cortex of mice. …”
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