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Enhancement of anti‐sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2‐targeted CAR
Published 2025-01-01“…Innovations in mRNA‐based engineering. This study demonstrates the feasibility of transient mRNA transfection to engineer NK cells for CAR expression, offering a non‐integrative and safer alternative to viral transduction. …”
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Enhanced rational protein engineering to reduce viscosity in high-concentration IgG1 antibody solutions
Published 2025-12-01“…Here, we take an enhanced rational design approach to reduce RSA via protein engineering. Using hydrogen-deuterium exchange mass spectrometry (HDX-MS), we identified potential self-interaction hotspots on the surface of an in-house IgG1 which has known viscosity issues at high concentration. …”
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Numerical and Experimental Investigation of Damage and Failure Analysis of Aero-Engine Electronic Controllers Under Thermal Shock
Published 2025-07-01“…The Engine Electronic Controller (EEC), as the core component of an aircraft engine control system, is vulnerable to rapid failure when exposed to thermal shock during engine fire incidents, potentially leading to catastrophic aviation accidents. …”
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A self-growth convolution network for thermal and mechanical fault detection with very limited engine data
Published 2024-12-01“…The self-growth scheme is proposed to disrupt the coadaptation between layers and that between kernels in order to mitigate the overfitting issue of small-sample cases. The SGNet is verified and implemented in the PHM of a heavy-duty diesel engine. …”
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289
Assembly plant simulation to support decision-making n Layout Design considering safety issues. A case study.
Published 2016-12-01“…This paper presents a simulation model that has been created to support decision-making during the layout redesign of an engine and transmission assembly plant in the automotive sector. …”
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Resolving Sub-Cycle Overvoltage Issue in Solar and Type-4 Wind Farms Employing Low Voltage Ride Through
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292
Analysis of Stirling engine’s performance in recovering waste heat from wood pellet, coconut husk and bagasse
Published 2025-03-01“…Nevertheless, a sizable portion of thermal energy is frequently lost to the environment as flue gas throughout the process. Stirling engine: a very efficient external combustion engine and little emissions as compared to other available engines, would be a good solution to overcome this issue as it can be used with any type of heat source. …”
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Public water risk concerns triggered by energy-transition-mineral mining
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295
Naive Bayes Analysis for Nutritional Fulfillment Prediction in Children
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Research on a public-private partnership scheme for space industry creation
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298
Software sustainability of global impact models
Published 2024-12-01“…We found that 29 % (32 out of 112) of the global impact models (GIMs) participating in the Inter-Sectoral Impact Model Intercomparison Project were accessible without contacting the developers. …”
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Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease
Published 2025-05-01“…Keywords: Alzheimer’s disease, engineering exosomes, intranasal delivery…”
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Fragility Analysis of Overturning Resistance of Hybrid Base-Isolated Structures in Diesel Engine Buildings of Nuclear Power Plants
Published 2025-03-01“…This paper validates the effectiveness of the modeling approach based on the finite element analysis of shaking table tests, establishing finite element models for both a base-isolated structure and a hybrid base-isolated structure designed to address overturning issues in the diesel engine building of a nuclear power plant. …”
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