INFLUENCE OF bFGF, SDF-1α, OR VEGF INCORPORATED INTO TUBULAR POLYMER SCAFFOLDS ON THE FORMATION OF SMALL-DIAMETER TISSUE-ENGINEERED BLOOD VESSEL IN VIVO by L. V. Antonova, V. V. Sevostyanova, A. G. Kutikhin, Е. A. Velikanova, V. G. Matveeva, T. V. Glushkova, A. V. Mironov, E. O. Krivkina, O. L. Barbarash, L. S. Barbarash

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Research progress,key scientific issues,and prospects of segmented fracturing and pressure relief gas drainage technology for coal seam roof horizontal wells by Ke YANG, Zhainan ZHANG, Xinzhu HUA, Wenjie LIU, Xin LYU, Xiaolou CHI, Changcheng WANG, Caiqing LI

“…The segmented fracturing and pressure relief gas drainage technology in the horizontal well of the coal seam roof is a key means to guide the efficient gas extraction in deep, high gas, soft and low permeability coal seams.Based on this, a full lifecycle development concept for the segmented fracturing, pressure relief,and gas drainage engineering of the coal seam roof horizontal well is proposed, including three stages: early scientific planning, mid-term engineering construction, and later safety management.This paper summarizes the research progress on the full life cycle development of segmented fracturing and pressure relief gas drainage in coal seam roof horizontal wells, constructs an overall research framework for key scientific issues related to segmented fracturing and pressure relief gas drainage in coal seam roof horizontal wells, and looks forward to its future development direction.The results show that the expansion of segmented fracturing cracks in the horizontal well of the coal seam roof is extremely complex due to geological factors, construction parameters, and physical properties.It is urgent to comprehensively evaluate the primary and secondary relationships under the influence of multiple factors in crack expansion, and reveal the mechanism of coal seam roof fracturing crack expansion under the influence of multiple factors.Exploring the critical relationship between the coupling of stress, water, temperature, and coal factors on the promotion and inhibition of coalbed methane adsorption, desorption, and migration, and establishing an optimal model for coalbed methane adsorption and desorption under multiple critical indicators, is the key to achieving efficient coalbed methane extraction. …”
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Co-stimulation of CD28/CD40 signaling molecule potentiates CAR-T cell efficacy and stemness by Wannakorn Khopanlert, Pongsakorn Choochuen, Kajornkiat Maneechai, Nawaphat Jangphattananont, Socheatraksmey Ung, Shingo Okuno, Peter Steinberger, Judith Leitner, Surasak Sangkhathat, Pongtep Viboonjuntra, Seitaro Terakura, Jakrawadee Julamanee

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Engineering a Graphene Quantum Dot‐Enhanced Surface Plasmon Resonance Sensor for Ultra‐Sensitive Detection of Hg2⁺ Ions by Recep Üzek

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Infill Modelling Influence on Dynamic Identification and Model Updating of Reinforced Concrete Framed Buildings by Marco Bovo, Michele Tondi, Marco Savoia

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Stability and Degradation Issues of Manganese Violet Pigment in Polymeric Paints: Morphological and Chemical Changes Under SO₂ and Humidity Exposure by Laura Pagnin, Giulia Cardin, Valentina Pintus, Michele Back, Farkas Pintér, Katja Sterflinger, Francesca Caterina Izzo

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Science, Technology, Engineering and… Masculinity? How psychological theory can help understand and improve the gender gap within STEM subjects by Misha Vickers

“…The under-representation of females in science, technology, engineering and mathematics (STEM) is a key educational issue which warrants discussion. …”
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Domain-Specific Knowledge Graph for Quality Engineering of Continuous Casting: Joint Extraction-Based Construction and Adversarial Training Enhanced Alignment by Xiaojun Wu, Yue She, Xinyi Wang, Hao Lu, Qi Gao

“…Our method can adapt the domain features and construct a high-quality knowledge graph for the quality engineering of continuous casting, providing an efficient solution for billet defect issues.…”
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Allocation of Interline Power Flow Controller-Based Congestion Management in Deregulated Power System by Muhammad Safdar Sial, Qinghua Fu, Talles Vianna Brugni

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Oncolytic herpes simplex virus reprograms cancer-associated fibroblasts to enhance antitumor immunity in pancreatic cancer by Feilong Zhou, Kailu Yang, Haoran Wang, Minghui Han, Dongping Zhang, Jie Wang, Han Wang, Yi Wang, Fengcongzhe Gong, Hao Zheng, Yanqin Liu, Jiliang Zhao, Meiyi Xu, Youjia Cao, Cuizhu Zhang

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Intrinsic immunosuppressive features of monocytes suppress CAR-T19 through IL-1 pathway modulation in mantle cell lymphoma by Kun Yun, R. Leo Sakemura, Ismail Can, Omar Gutierrez Ruiz, Ekene J. Ogbodo, Shuwen Zhang, Ateka Saleh, Truc N. Huynh, Claudia Manriquez Roman, Olivia L. Sirpilla, Carli M. Stewart, James H. Girsch, Jennifer M. Feigin, Long Mai, Hong Xia, Brooke Kimball, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Fariborz Rakhshan Rohakhtar, Vernadette Simon, Elizabeth L. Siegler, Mike Mattie, Sao-Mai Nguyen-Mau, Simone Filosto, Saad S. Kenderian

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Three novel cost-sensitive machine learning models for urban growth modelling by Mohammad Ahmadlou, Mohammad Karimi, Saad Sh. Sammen, Karam Alsafadi

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Environmental and energy issues in biodiesel production using palm oil from the interspecific hybrid OxG and Elaeis guineensis: a case study in Colombia☆ by Mogollon Diego Ignacio Nieto, Venturini Osvaldo José, Batlle Eric Alberto Ocampo, González Aldemar Martinez, Munar-Florez David Arturo, Ramirez-Contreras Nidia Elizabeth, García-Nuñez Jesús Alberto, Borges Pedro Tavares, Lora Electo Eduardo Silva

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Soil erosion prediction using the Revised Universal Soil Loss Equation (RUSLE) in Google Earth Engine (GEE) cloud-based platform by S. Papaiordanidis, I.Z. Gitas, T. Katagis

“…Thus, soil erosion and soil loss are a serious issue that should be managed, in order to conserve both artificial and natural ecosystems. …”
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Real-Time Intelligent Recognition and Precise Drilling in Strongly Heterogeneous Formations Based on Multi-Parameter Logging While Drilling and Drilling Engineering by Aosai Zhao, Yang Yu, Bin Wang, Yewen Liu, Jingyue Liu, Xubiao Fu, Wenhao Zheng, Fei Tian

“…Facing engineering challenges of real-time and high-precision recognition of strongly heterogeneous formations during directional drilling, it is crucial to address the issues of sparse lithology geological labels and multi-source lithology identification from LWD data. …”
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A New Approach to Studying Net Present Value and the Internal Rate of Return of Engineering Projects under Uncertainty with Three-Dimensional Graphs by Alexander Maravas, John-Paris Pantouvakis

“…Cost-benefit analysis (CBA) is very useful when appraising engineering projects and examining their long-term financial and social sustainability. …”
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Engineering Bifunctional Calcium Alendronate Gene‐Delivery Nanoneedle for Synergistic Chemo/Immuno‐Therapy Against HER2 Positive Ovarian Cancer by Guochuang Chen, Leli Zeng, Bo Bi, Xiuyu Huang, Miaojuan Qiu, Ping Chen, Zhi‐Ying Chen, Yulong He, Yihang Pan, Yu Chen, Jing Zhao

“…To address these critical issues, the design and engineering of alendronate calcium (CaALN) based gene‐delivery system is reported to express therapeutic level of BiTE (HER2×CD3) for efficient ovarian cancer immunotherapy. …”
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Modelling of the Bubble Size Distribution in an Aerated Stirred Tank: Theoretical and Numerical Comparison of Different Breakup Models by Kálal Zbyněk, Jahoda Milan, Fořt Ivan

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Challenges issues and future recommendations of deep learning techniques for SARS-CoV-2 detection utilising X-ray and CT images: a comprehensive review by Md Shofiqul Islam, Fahmid Al Farid, F. M. Javed Mehedi Shamrat, Md Nahidul Islam, Mamunur Rashid, Bifta Sama Bari, Junaidi Abdullah, Muhammad Nazrul Islam, Md Akhtaruzzaman, Muhammad Nomani Kabir, Sarina Mansor, Hezerul Abdul Karim

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Characterization and Modelling of LeBlanc Hydrodynamic Stabilizer: A Novel Approach for Steady and Transient State Models by Marlon Wesley Machado Cunico

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