From endothelial dysfunction correction to macrohemodynamics improvement in patients with chronic cor pulmonale by V. S. Zadionchenko, I. V. Pogonchenkova, A. M. Shchikota, O. I. Nesterenko, K. A. Aldushina, T. M. Terekhova

“…CCP patients were characterised by substantial endothelial dysfunction (ED), pathological NO hyper-production, elevated level of Willebrand factor, and increased apoptosis. …”
Get full text

ACTIVITY MODULATION OF VARIOUS NITRIC OXIDE SYNTASES AS AN APPROACH TO ENDOTHELIAL DYSFUNCTION THERAPY by D. V. Kurkin, E. E. Abrosimova, D. A. Bakulin, N. S. Kovalev, M. A. Dubrovina, A. V. Borisov, A. V. Strygin, E. I. Morkovin, I. N. Tyurenkov

“…As a therapeutic approach, modulation of the nitric oxide synthase activity can be implemented to treat endothelial dysfunction, which is the cause for complications of many diseases.…”
Get full text

Diagnosis and Treatment of Manifestations of Endothelial Dysfunction in ICU Patients with Severe Acute Pancreatitis by V. V. Kiselev, M. S. Zhigalova, S. S. Petrikov, E. V. Klychnikova, P. A. Yartsev

“…An important pathogenetic aspect of the severe course of acute pancreatitis is endothelial dysfunction. The latter often begins as a diffuse activation of coagulation, which further potentiates the progression of the systemic inflammatory response syndrome and, thereby, complicates the course of acute pancreatitis. …”
Get full text

Mitochondrial Dysfunction in Endothelial Cells: A Key Driver of Organ Disorders and Aging by Elena Grossini, Sakthipriyan Venkatesan, Mohammad Mostafa Ola Pour

Get full text

Effect of pentoxifylline on endothelial dysfunction, oxidative stress and inflammatory markers in STEMI patients by Asmaa Saeed, Mohamed Moustafa Farouk, Nagwa Ali Sabri, Mohamed Ayman Saleh, Marwa Adel Ahmed

“…Aim: ST-elevation myocardial infarction (STEMI) patients suffer higher mortality and adverse outcomes linked to endothelial dysfunction (ED). Methods: 43 patients were randomized to pentoxifylline (PTX) 400 mg thrice daily (n = 22) or placebo (n = 21). …”
Get full text

Adenosine Monophosphate-Activated Protein Kinase, Oxidative Stress, and Diabetic Endothelial Dysfunction by Ming-Hui Zou, Shengnan Wu, Tianyu Xu, Xiaoxia Fu.

“…Overwhelming data from human and animals demonstrate that the endothelial dysfunction associated with diabetes is due to the local formation of oxidants and free radicals. …”
Get full text

Endothelial dysfunction and its correction with perindopril therapy in patients with coronary heart disease by O. A. Vartanova, N. V. Mikhailova, T. E. Morozova

“…Aim. To investigate endothelial dysfunction (ED) in patients with coronary heart disease (CHD), stable effort angina, Functional Class (FC) I-III, as well as to study perindopril potential in ED correction.Material and methods. …”
Get full text

The effectiveness of complex treatment of endothelial dysfunction in patients with primary open angle glaucoma by A. M. Dusmukhamedova, D. M. Tuychibaeva, A. A. Khadzhimetov

“…An increased level of endothelin-1 and Willebrand factor, as well as a low VEGF level in POAG patients indicate the role of these pathogenetic factors in the formation of endothelial dysfunction. …”
Get full text

Effect of plant-based functional foods for the protection against salt-induced endothelial dysfunction by Sheung Yin San, Jennifer. M.F. Wan, Jimmy Chun Yu Louie

Get full text

ENDOTHELIAL PROTECTIVE EFFECTS OF KLYMADINON IN EXPERIMENTAL OVARIECTOMY by A. M. Anishchenko, T. M. Plotnikova

“…A Endothelial protective and antithrombogenic effects of Cimicifuga racemosa standardized extract (Klimadynon, Bionorica, Germany) in comparison with ethinylestradiol in experimental ovariectomy were investigated. …”
Get full text

PERIPHERAL ARTERY REMODELLING AS ENDOTHELIAL DYSFUNCTION PREDICTOR IN PATIENTS WITH ARTERIAL HYPERTENSION AND ABDOMINAL OBESITY by N. N. Molchanova, I. A. Zagretdinov, A. M. Teregulova, L. N. Mingazitdinova, E. G. Mutalova, L. B. Novikova

“…The stiffness, elasticity, and endothelial vasodilatation of common carotid artery (CCA), femoral artery (FA) and renal arteries (RA) were examined in 60 patients with arterial hypertension (AH) and obesity, as well as in 20 patients with essential AH (EAH). …”
Get full text

ASSESSMENT OF MARKERS OF HEMOSTASIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PROGRESSIVE OBLITERATING LOWER LIMB ATHEROSCLEROSIS by E. A. Korymasov, E. P. Krivoshchekov, A. V. Kazantsev, D. L. Pribytkov, P. N. Zolotarev

“…Progressive course of obliterating atherosclerosis is associated with hypercoagulation (increased platelet aggregation activity, shortened aPTT, PT, TT, increased levels of fibrinogen, SFMCs, and D-dimer), as well as with endothelial dysfunction (increased levels of endothelin-1, von Willebrand factor, homocysteine, and Creactive protein).…”
Get full text

Endothelial activation and dysfunction caused by influenza A virus (<i>Alphainfluenzavirus influenzae</i>) by Vladimir A. Marchenko, Irina N. Zhilinskaya

“…Severe forms of influenza are usually characterized by vascular endothelial cells damage. Thus, influenza A viruses, including subtypes A(H1N1)pdm09, A(H3N2), as well as highly pathogenic avian influenza viruses, can infect the vascular endothelium, leading to activation and subsequent dysfunction of these cells. …”
Get full text

Association of Monocyte-to-HDL Cholesterol Ratio with Endothelial Dysfunction in Patients with Type 2 Diabetes by Huihui Zhang, Jun Lu, Jie Gao, Wenjun Sha, Xinhua Cai, Mai Re Yan Mu Rouzi, Yuanying Xu, Wenjun Tang, Tao Lei

“…Patients with endothelial dysfunction had higher MHR (p<0.05) than those without endothelial dysfunction. …”
Get full text

GPR68 Mediates Lung Endothelial Dysfunction Caused by Bacterial Inflammation and Tissue Acidification by Pratap Karki, Yunbo Ke, Chenou Zhang, Kamoltip Promnares, Yue Li, Charles H. Williams, Charles C. Hong, Konstantin G. Birukov, Anna A. Birukova

“…Altogether, these results suggest that GPR68 is a critical mediator of acidic pH-induced dysfunction of human pulmonary vascular endothelial cells and mediates the augmenting effect of tissue acidification on LPS-induced endothelial cell injury.…”
Get full text

Reduced Circulating Endothelial Progenitor Cells and Downregulated GTCPH I Pathway Related to Endothelial Dysfunction in Premenopausal Women with Isolated Impaired Glucose Toleranc... by Juan Liu, Xiangbin Xing, Xinlin Wu, Xiang Li, Shun Yao, Zi Ren, Haitao Zeng, Shaohong Wu

Get full text

Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia. by Rozana Santos Teixeira, Regina Terse-Ramos, Tatiane Anunciação Ferreira, Vinícius Ramos Machado, Marya Izadora Perdiz, Isa Menezes Lyra, Valma Lopes Nascimento, Ney Boa-Sorte, Bruno B Andrade, Ana Marice Ladeia

“…<h4>Background</h4>Hematological changes can drive damage of endothelial cells, which potentially lead to an early endothelial dysfunction in patients with sickle cell anemia (SCA). …”
Get full text

Study of vascular endothelial dysfunction in children with beta-thalassemia major before and after quercetin therapy by Fatma Al Zahraa Sherai, Maaly Mabrouk, Ibrahim Badraia, Adel Hagag, Eman Elaskary

“…The free hemoglobin oxidation generates reactive oxygen species (ROS), free heme, and iron, thus inducing membrane oxidative damage as well as vascular endothelial dysfunction. Quercetin has a crucial impact on enhancing endothelial dysfunction in thalassemia major. …”
Get full text

ENDOTHELIAL DYSFUNCTION AND ITS CORRECTION WIT CYTOPROTECTORS IN PATIENTS WITH STABLE EFFORT ANGINA AND ARTERIAL HYPERTENSION by F. E. Khlebodarov, P. Yu. Turikov, V. P. Mikhin

“…Adding cardiocytoprotectors to the complex therapy improved endothelium-dependent vasodilatation and circadian BP profile, as well as reduced endothelial dysfunction severity and intima-media thickness in AH patients. …”
Get full text

Metabolomics in drugs research on zebrafish-based cardiotoxicity models: endothelial and mitochondrial dysfunction, oxidative stress by N. E. Moskaleva, P. M. Rezvanov, V. M. Samoylov, V. G. Varzieva, S. N. Baskhanova, V. V. Tarasov, E. A. Smolyarchuk, D. A. Kudlay, S. A. Appolonova

“…An increase in the concentration of ADMA is associated with endothelial dysfunction, and an increase in methionine sulfoxide is associated with increased oxidative stress.…”
Get full text