Efficacy of opioid-free anesthesia in reducing postoperative nausea and vomiting following gynecological laparoscopic surgery: a randomized controlled trial by Yanan Shen, Yanan Shen, Yuanyuan Wu, Yuanyuan Wu, Qianqian Tang, Qianqian Tang, Yilong Wang, Yilong Wang, Wei Ma, Wei Ma, Jianwei Wang, Jianwei Wang

“…This study aimed to evaluate the efficacy of OFA in reducing PONV and its impact on postoperative recovery.MethodsThis randomized, double-blind, controlled trial enrolled 92 female patients undergoing elective gynecological laparoscopic surgery. …”
Get full text

Dexmedetomidine versus Dexamethasone as an Adjuvant to Ropivacaine in Transversus Abdominis Plane Block in Infraumbilical Surgeries for Postoperative Analgesia: A Randomised Clinic... by Anupama Kumari, Aarjvi Patel, Payal Berawala, Sara Mary Thomas

“…The secondary objective was to compare postoperative haemodynamic changes and side effects. Materials and Methods: In this randomised double-blinded prospective clinical study, conducted in the Department of Anaesthesia, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (SBKS MIRC), Piparia, Vadodara, Gujarat, India from March 2023 to September 2024. 80 patients of American Society of Anaesthesiologists (ASA) I and II, aged 18-60 years, undergoing elective infraumbilical surgeries (open abdominal hysterectomy and open bilateral inguinal hernia repair) under spinal anaesthesia were randomly allocated into two groups of 40 patients each. …”
Get full text

Comparative analysis of the functional status of hip joints before total hip replacement in patients with ankylosing spondylitis, rheumatoid arthritis and coxarthrosis: preliminary... by A. O. Dubinin, A. E. Khramov, T. V. Dubinina, E. V. Ilinykh, E. I. Byalik

“…All patients underwent elective THA between 1998 and 2020. Among AS patients, men (80.6%) predominated. …”
Get full text

Ultra-Long-Term CT Angiography Evaluation of Patients Treated with Covered Stents for Visceral Aneurysms: A Single Center Case Series by Marcello Andrea Tipaldi, Nicolò Ubaldi, Edoardo Ronconi, Michela Ortenzi, Francesco Arbia, Gianluigi Orgera, Miltiadis Krokidis, Tommaso Rossi, Pasqualino Sirignano, Luigi Rizzo, Michele Rossi

“…Six of the seven patients underwent elective procedures with no significant periprocedural complications. …”
Get full text

Comparison of the Effects of Two Different Low-Doses of Isobaric Bupivacaine on Intraoperative Hemodynamics under Spinal Anaesthesia during Caesarean Section: A Randomized Controll... by Aysenur Dostbil, Canan Atalay, Ilker Ince, Mehmet Aksoy, Ozgur Ozmen, Kamber Kasali, Omer Erkan Yapca, Tugberk Kucun, Ayse Nur Aksoy, Gamze Nur Cimilli Senocak

“…Background: The objective of this study was to conduct a randomized controlled trial in order to examine the hemodynamic impacts of two different doses of intrathecal isobaric bupivacaine (5 mg and 7 mg) when combined with 15 µg fentanyl in the context of patients undergoing caesarean section under combined spinal epidural anesthesia. Methods: Eighty patients with American Society of Anesthesiologists physical status I and II, aged between 16–50 years, who would undergo elective caesarean section under combined spinal epidural anaesthesia were randomly allocated to Group A and Group B (n = 40, for each group). …”
Get full text

Proton Pump Inhibitor Use Following Esophageal Variceal Ligation and Its Impact on Clinical Outcomes: Real-World Data from the TriNetX Global Collaborative Network by Nisar Amin, Harleen Chela, Muhammad Faisal Mubarak, Mark Ayoub, Ebubekir Daglilar

“…This study utilizes the TriNetX global health research network to evaluate the outcomes of PPI use following elective EVL for primary prophylaxis. <b>Methods:</b> This retrospective cohort study was conducted using the TriNetX database to evaluate adult patients with cirrhosis and esophageal varices who underwent EVL for primary prophylaxis. …”
Get full text

Erector spinae plane block versus transversus abdominis plane block for analgesia after cesarean section: a systematic review and meta-analysis by Mariana AbdElSayed Mansour, Saeed Baradwan, Ahmed Abdelaziz Shama, Mohamed Ali Mahmoud, Ayman Salah Abouelnour, Ayman Mohamed AbdelWahed Mohamed, Ahmed Fathi Hassan Elkhouly, Abdelkarem Hussiny Ismail Elsayed, Zaky Ftouh Rashed, Ahmed Mohamed Abdelhakim, Mrooj Mabruk Almutairi, Mohamed A. Lotfy, Ahmed Goda Ahmed

“…The inclusion criteria followed the PICOS framework: Population (women undergoing elective cesarean delivery), Intervention (ESPB), Comparator (TAPB), Outcomes (postoperative pain, opioid consumption, analgesic duration, and satisfaction), and Study Design (randomized controlled trials). …”
Get full text

Influence of open surgical and endovascular abdominal aortic aneurysm repair on clot quality assessed by ROTEM® test by Šarac Momir, Marjanović Ivan, Bezmarević Mihailo, Šarac Sanja, Milić Rade, Obradović Slobodan, Tomić Aleksandar

“…The aim of this study was to compare the impact of OR and EVAR of AAA on clot quality assessed by rotational thromboelastometry (ROTEM®) tests. Methods. The study included 40 patients who underwent elective AAA surgery and were devided into two groups (the OR and the EVAR group - 20 patients in each group). …”
Get full text

An impact of neutrophil extracellular traps to the prothrombotic state and tumor progression in gynecological cancer patients by E. V. Slukhanchuk, V. O. Bitsadze, A. G. Solopova, J. Kh. Khizroeva, N. D. Degtyareva, D. V. Shcherbakov, J.-C. Gris, I. Elalamy, A. D. Makatsariya

“…In addition, NET-related effect on tumor progression and metastasis has been actively studied.Aim: to evaluate NET-related procoagulant activity in gynecological cancer patients.Materials and Methods. From April 2020 to October 2022, a prospective controlled interventional non-randomized study was conducted with 120 women. …”
Get full text

Early Postoperative Increase in Transforming Growth Factor Beta-1 Predicts Microvascular Flap Loss in Reconstructive Surgery: A Prospective Cohort Study by Rihards Peteris Rocans, Janis Zarins, Evita Bine, Insana Mahauri, Renars Deksnis, Margarita Citovica, Simona Donina, Sabine Gravelsina, Anda Vilmane, Santa Rasa-Dzelzkaleja, Olegs Sabelnikovs, Biruta Mamaja

“…We aimed to investigate the predictive value of postoperative changes in transforming growth factor beta-1 (TGF-β1) for microvascular flap complications. <i>Materials and Methods:</i> This prospective observational study comprised 44 adults scheduled for elective microvascular flap surgery. …”
Get full text

Study protocol for an observational cohort evaluating incidence and clinical relevance of perioperative elevation of high-sensitivity troponin I and N-terminal pro-brain natriureti... by Ekaterine Popova, Ángel Candela-Toha, María Alonso, Diego Parise, Míriam de Nadal, Ascencion Martin-Grande, Javier Pérez-Vélez, Juan Carlos Trujillo, Luis Gajate, Marcos de Miguel, Anna González-Tallada, Elisabeth Martínez-Téllez, Esther Cladellas-Gutierrez, Georgina Planas, Angélica de Pablo

“…We designed our cohort study to evaluate perioperative elevation of both high-sensitivity troponin I (hs-TnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients undergoing lung resection and to establish a risk score for major cardiovascular postoperative complications.Methods and analysis We will conduct a prospective, multicentre, observational cohort study, including 345 patients undergoing elective thoracic surgery for lung resection. …”
Get full text

Prevalence of fetal anomalies, stillbirth, neonatal morbidity, or mortality in pregnancies complicated by placenta accreta spectrum disorders by Pedro Viana Pinto, Katarzyna Kawka‐Paciorkowska, Maddalena Morlando, Hubert Huras, Magdalena Kołak, Charline Bertholdt, Andrzej Jaworowski, Thorsten Braun, Karin A. Fox, Olivier Morel, Alexander Paping, Vedran Stefanovic, Mina Mhallem, Heleen J. Van Beekhuizen, IS‐PAS group

“…For the calculation of neonatal morbidity and mortality, all elective pregnancy terminations were excluded, hence 311 pregnancies with 323 newborns were analyzed. …”
Get full text

Expression and Correlation of Complement C3 and C4 in Serum and Maternal-Fetal Interface in Patients with Unexplained Recurrent Spontaneous Abortion: A Prospective Cohort Study by Zhengxin Zhou, Huixia Xie, Miao Liu, Ruopeng Li, Wenjing Jiang, Yan Zheng, Qun Lv

“…Background: In this study, we sought to detect the expression of complement C3 and C4 in serum and maternal-fetal interface in patients with unexplained recurrent spontaneous abortion, and analyze their correlation, in order to explore the clinical significance and role of C3 and C4 in unexplained recurrent spontaneous abortion. Methods: In a prospective cohort study, products of conception of 20 women who underwent curettage due to unexplained recurrent spontaneous abortion in the Department of Obstetrics and Gynecology at the Sichuan Provincial People’s Hospital from December 2021 to December 2022 were chosen as the case group, and 23 healthy early-pregnancy women who underwent elective abortion due to personal reasons during the same period were chosen as the control group. …”
Get full text

Direct Gallbladder Extraction versus Endobag Extraction during Laparoscopic Cholecystectomy: A Prospective Observational Study by Swathy Elangovan, K Vivekananda Subramania Nathan, R Sivamarieswaran, M Reegan Jose

“…A total of 60 patients undergoing elective LC were randomised into two groups: Group A (direct extraction) and Group B (endobag extraction). …”
Get full text

Long-term impact of diabetes on mortality in patients undergoing unprotected left main PCI: a propensity score-matched analysis from the BIA-LM registry by Paweł Kralisz, Emil Julian Dąbrowski, Sławomir Dobrzycki, Wiktoria Urszula Kozłowska, Patrycja Oliwia Lipska, Konrad Nowak, Kamil Gugała, Przemysław Prokopczuk, Grzegorz Mężyński, Michał Święczkowski, Marcin Kożuch

“…After PSM subgroup analysis showed worse outcomes for patients with diabetes undergoing two-stent angioplasty (HR 3.70, 95% CI 1.64–8.34, P = 0.002) and elective PCI (HR 2.07, 95% CI 1.29–3.31, P = 0.003). …”
Get full text

Comparison of Oliceridine and Morphine in Postoperative Analgesia in Laparoscopic Total Hysterectomy, a Randomized Double-Blind Controlled Trial by Duan J, Wang X, Hou C, Yu T, Ju X, Wang S

“…Jinjuan Duan,&amp;ast; Xing Wang,&amp;ast; Chengjing Hou, Tong Yu, Xia Ju, Shengbin Wang Department of Anesthesiology, Affiliated Anqing Medical Centre of Anhui Medical University, Affiliated Anqing Hospital of China Pharmaceutical University, Anqing Municipal Hospital, Anqing, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Xia Ju, Department of Anesthesiology, Affiliated Anqing Medical Centre of Anhui Medical University, Affiliated Anqing Hospital of China Pharmaceutical University, Anqing Municipal Hospital, No. 87 Tianzhushan East Road, Anqing, 246000, People’s Republic of China, Tel +86-13685563136, Email alcon2006@126.com Shengbin Wang, Department of Anesthesiology, Affiliated Anqing Medical Centre of Anhui Medical University, Affiliated Anqing Hospital of China Pharmaceutical University, Anqing Municipal Hospital, No. 87 Tianzhushan East Road, Anqing, 246000, People’s Republic of China, Tel +86-13955665151, Email shbw1965@126.comPurpose: Compare the analgesic efficacy and safety profiles of oliceridine and morphine in patient-controlled intravenous analgesia (PCIA) after laparoscopic total hysterectomy.Materials and Methods: This prospective, double-blind trial randomly allocated 60 patients undergoing elective laparoscopic total hysterectomy in a 1:1 ratio to receive either oliceridine (group O) or morphine (group M) via PCIA. …”
Get full text

Perioperative Elevation in Cell-Free DNA Levels in Patients Undergoing Cardiac Surgery: Possible Contribution of Neutrophil Extracellular Traps to Perioperative Renal Dysfunction by Yu Qi, Tokujiro Uchida, Mamoru Yamamoto, Yudai Yamamoto, Koji Kido, Hiroyuki Ito, Nagara Ohno, Miho Asahara, Yoshitsugu Yamada, Osamu Yamaguchi, Chieko Mitaka, Makoto Tomita, Koshi Makita

“…Eighty patients undergoing elective cardiac surgery were studied. Serum samples were collected at baseline, immediately after surgery, and the day after surgery (POD-1). …”
Get full text

Trends, Patient Outcomes, and Resource Utilization Associated with Surgical Staplers During Robotic Sleeve Gastrectomy by Pan IW, Siddiqui ZA

“…Patients were included if they underwent elective, inpatient, primary sleeve gastrectomy performed using the Intuitive Surgical robotic system (Sunnyvale, CA) with either a bedside stapler (BS, Signia™, Endo-GIA™, or Tri-staple™) or a robotic stapler (RS, Sureform™). …”
Get full text

Protocol for the REBOUND study: a cohort study to uncover fundamental mechanisms of accelerated ageing and impaired resilience following cancer surgery and treatment by Carly Welch, Animesh Acharjee, Rebecca Birch, João Pedro de Magalhães, Niharika A. Duggal, Alison Hainsworth, Jose R. Hombrebueno, Simon W. Jones, Jonathan Lewis, Ali Mazaheri, Helen M. McGettrick, Thomas Nicholson, Judith Partridge, Thomas Pinkney, Claire J Steves, Kristina Tomkova, Daisy Wilson, Thomas A Jackson

“…Cancer surgery and treatment may be associated with accelerated ageing in some older people; studying this process will improve understanding to enable treatments to prevent adverse effects on physical and cognitive function. Methods This study will recruit 172 participants aged 65 years and older scheduled to undergo elective colorectal surgery for cancer from two hospital sites (Guy’s and St Thomas’ NHS Foundation Trust and University Hospitals Birmingham NHS Foundation Trust). …”
Get full text

Oxycodone for analgesia in children undergoing endoscopic retrograde cholangiopancreatography: a randomized, double-blind, parallel study by Wei Ji, Wei Ji, Liping Sun, Liping Sun, Yue Huang, Yue Huang, Jie Bai, Jie Bai, Jijian Zheng, Jijian Zheng, Kan Zhang, Kan Zhang

“…Eighty-two pediatric patients aged 2–18 years who were scheduled for elective ERCP were randomly assigned to receive either oxycodone (0.2 mg/kg) or fentanyl (2 μg/kg). …”
Get full text