Effects of different doses of remimazolam on the quality of sedation and cardiac function in elderly patients: a double-blind randomised controlled study by Liu Minghong, Qizhu Feng, Huichun Chen, Ju Li, Jun Shi

“…BackgroundWe intended to observe the effects of different doses of remimazolam besylate via intravenous induction on the quality of sedation and cardiac function in elderly patients.MethodsA total of 135 ASA I–III patients undergoing elective laparoscopic cholecystectomy were selected. …”
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Ultrasound-guided mandibular nerve block combined with superficial cervical plexus nerve block in patients undergoing radical surgery for tongue canceron: a randomized controlled t... by Yongjun Liu, Wenjie Sun, Shibiao Chen, Shiping Yin, Gaofeng Fan

“…Given the considerable size of the surgical area and the prolonged duration associated with radical tongue cancer procedures, these factors significantly hinder postoperative recovery, particularly in elderly patients. Methods For this study, 60 patients scheduled for elective radical tongue cancer surgery were enlisted. …”
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The perioperative administration of dexamethasone and infection (PADDI) trial protocol: rationale and design of a pragmatic multicentre non-inferiority study by David Story, Allen C Cheng, Andrew B Forbes, Kate Leslie, Tomás B Corcoran, Paul S Myles, Ed O'Loughlin, Timothy G Short, Matthew TV Chan, Pauline Coutts, Jaspreet Sidhu, Leon A Bach, Kwok M Ho, Chris Frampton, Richard Macisaac, Michael Paech, Bala Venkatesh, Leon Worth, Stephane Heritier, Cathy Martin, Roger Browning, Emma Hamilton, Paul Ingram, Peter Boan

“…The safety of the administration of this immunosuppressive agent at a time of significant immunological disruption has not been rigorously evaluated in terms of infective complications.Methods/analysis This is a pragmatic, multicentre, randomised, controlled, non-inferiority trial. …”
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Quality improvement of pediatric colonoscopy by application of bundle and centralization: A single-center review by Shu-Chao Weng, Hung-Chang Lee, Chun-Yan Yeung, Wai-Tao Chan, Hsuan-Chih Lao, Chuen-Bin Jiang

“…Background: To assess the quality change of our single-center pediatric colonoscopy after applying bundle for bowel preparation and general anesthesia and centralize the procedure using terminal ileum (TI) intubation rate as the main indicator. Methods: All elective colonoscopies performed for patients younger than 18 years old in MacKay Memorial Hospital from July 2015 through June 2020 (assigned to group 1, before bundle) and from August 2020 through July 2021 (assigned to group 2, after bundle) were retrospectively reviewed for demographic characteristics, indications, bowel preparation agent and cleansing level, diagnostic and therapeutic procedures, maximum intestinal level reached, and cecal intubation and total procedure time. …”
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Perioperative outcomes at three rural Rwandan district hospitals: a 28-day prospective observational cohort study by Fredrick Kateera, Robert Riviello, Mariella Munyuzangabo, Vincent Cubaka, Egide Mpanumusingo, Alphonse Nshimyiryo, Joel M Mubiligi, Marcel Nshunguyabahizi, Cyprien Shyirambere, Grace Umutesi, Jocelyn Mizero, John Kamau, Jean de Dieu Gatete, Mark W Newton, Bantayehu Sileshi

“…We assessed perioperative outcomes of patients undergoing surgical care at three Rwandan rural hospitals—Butaro District Hospital, Kirehe District Hospital and Rwinkwavu District Hospital—supported by Partners In Health/Inshuti Mu Buzima—an international non-governmental organisation.Methods We conducted a 6-month prospective observational cohort study at the three district hospitals. …”
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Neck dissection for advanced laryngeal cancer: Role and relevance in KwaZulu-Natal Province, South Africa by S S Gumede, M Motala, A Yakobi, A Sibiya, R Bipath

“…While this approach aligns with international guidelines, there is no consensus on whether elective neck dissection (END) should be incorporated during primary surgery for clinically negative neck nodes (cN0) or as a therapeutic option after nodal relapse. …”
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The use of transdermal therapeutic systems for chemical pleurodesis in a patient with prolonged air leakage after lung resection for cancer by D. A. Rozenko, N. D. Ushakova, S. N. Tikhonova, Yu. N. Lazutin, N. N. Popova, A. M. Skopintsev

“…The most common complication after elective lung resections is an alveolar-pleural fistula or prolonged air leakage. …”
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Efficacy and safety of hydromorphone for postoperative patient-controlled intravenous analgesia for patients undergoing orthopedic surgery: a randomized, double-blinded controlled... by Qi Wang, Yuanyuan Zhao, Bin Ling, Xiangxiang Chen, Yayun Xie, Haibo Zhao, Jiangang Zhang, Wei Wang, Jie Lv

“…BackgroundThe study aimed to evaluate the efficacy and safety of hydromorphone in postoperative patient-controlled intravenous analgesia (PCIA) for orthopedic surgery patients, offering a reference for postoperative pain management in this patient population.MethodsThis was a prospective, randomized, double-blinded, controlled trial involving 80 patients aged 23 to 64 years undergoing elective orthopedic surgery. …”
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Dexmedetomidine for the prevention of postoperative delirium in patients after intracranial operation for brain tumours (DEPOD study): a study protocol and statistical plan for a m... by Hongqiu Gu, Linlin Zhang, Jian-Xin Zhou, Xuan He, Kun-Ming Cheng, Xin Qu, Yuan Xu, Penglin Ma

“…The primary endpoint is the incidence of POD, which is assessed two times per day using the Confusion Assessment Method for the intensive care unit (ICU), during the first 5 postoperative days. …”
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Fibrinogen-to-albumin ratio (FAR) for predicting microvascular flap complications in reconstructive surgery by Rihards Peteris Rocans, Janis Zarins, Evita Bine, Insana Mahauri, Renars Deksnis, Margarita Citovica, Simona Donina, Indulis Vanags, Biruta Mamaja

“…We aimed to investigate the link between preoperative fibrinogen-to-albumin ratio (FAR) and various flap complications. Methods: This prospective cohort study included 130 adult patients who underwent elective microvascular flap surgery. …”
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Reducing incidence of postoperative acute kidney injury in trauma and orthopaedics patients: a quality improvement project by Huma Naqvi, Sreenadh Gella, Sanat Kulkarni, Thomas Richardson, Alice Green, Radhika Acharya, Arusa Latif, Dakota Johnson

“…This quality improvement project aimed to implement measures targeting known risk factors to decrease the incidence of postoperative AKI in trauma and orthopaedics (T&O) patients.Methods Data were collected across three six-month to 7-month cycles between 2017 and 2020, analysing all elective and emergency T&O operated patients within a single NHS Trust (n=714, 1008 and 928, respectively). …”
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Association between Preanaesthetic Check-up Parameters and Postoperative Recovery Score: A Cross-sectional Study by Sneha Henry, Moona Abdul Kadiru, R Shyam Krishnan, Harris Mohammed Paravengal, Keshav Anand, Mazhar Zulfikar

“…Introduction: Elective surgeries are typically preceded by a thorough health assessment conducted by an anaesthetist during the Preanaesthesia Check-Up (PAC). …”
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Comparison of remimazolam tosylate and propofol in hemodynamic stability, postoperative cognitive function, and recovery in general anesthesia combined with regional nerve blocks:... by Jiaman Li, Li Liao, Chunyang Shao, Yifeng Yang, Yan Tang, Qiang Wei, Li Xu

“…This study aimed to compare the hemodynamic effects and postoperative cognitive function between remimazolam tosylate and propofol in patients undergoing GA combined with RA. Methods A retrospective cohort study was conducted on 4408 patients who underwent elective upper or lower limb surgeries at our institution from January 2020 to June 2024. …”
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Increased B-type Natriuretic Peptide (NT-proBNP) Level as a Risk Factor in Cardiosurgical Patients by I. A. Kozlov, I. Ye. Kharlamova

“…Objective: to study the impact of increased inactive (N-terminal) pro-B-type natriuretic peptide (NT-proBNP) levels in cardiosurgical patients with coronary heart disease without drastically reducing left ventricular contractility on intraoperative central hemodynamics and the specific features of therapeutic measures for its stabilization. Subjects and methods. The inclusion criteria were elective surgery, age less than 70 years, a left ventricular ejection fraction of at least 30%, and no surgical complications. …”
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Elevated Zinc and Potassium Levels in Renal Calculi Indicate Distinct Pathophysiological Mechanisms in Urolithiasis by Maciej Jaromin, Marcin Cichocki, Tomasz Konecki, Piotr Kutwin, Waldemar Maniukiewicz, Piotr Wysocki, Magdalena Gajek, Małgorzata Iwona Szynkowska-Jóźwik, Dariusz Moczulski

“…The aim of this study is to compare differences between the trace element concentrations in male and female renal calculi as well as differences between the trace element concentrations in different stone types. Material and Methods: Renal calculi specimens were obtained during elective nephrolithotripsy procedures. …”
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Effects of Minimally Invasive Versus Open Pancreatoduodenectomy on Short-Term Surgical Outcomes and Postoperative Nutritional and Immunological Statuses: A Single-Institution Prope... by Shinsei Yumoto, MD, Hiromitsu Hayashi, MD, PhD, Kosuke Mima, MD, PhD, Daisuke Ogawa, MD, Rumi Itoyama, MD, PhD, Yuki Kitano, MD, PhD, Shigeki Nakagawa, MD, PhD, Hirohisa Okabe, MD, PhD, Hideo Baba, MD, PhD

“…The surgical advantages of MIPD over OPD are controversial, and the postoperative nutritional and immunological statuses are unknown. Methods:. In total, 306 patients who underwent MIPD (n = 120) or OPD (n = 186) for periampullary tumors from April 2016 to February 2024 were analyzed. …”
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Bowel preparation and surgical site infections in laparoscopic and robot‐assisted right‐sided colon cancer surgery with intracorporeal anastomosis: A retrospective study by Naoya Ozawa, Tomohiro Yamaguchi, Takumi Kozu, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Toshiki Mukai, Takashi Akiyoshi, Yosuke Fukunaga

“…Methods Patients (n = 150) with right‐sided colon cancer who underwent elective laparoscopic or robot‐assisted colectomy (2019 and 2023) were included. …”
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Assessment of Geriatric Problems and Risk Factors for Delirium in Surgical Medicine: Protocol for Multidisciplinary Prospective Clinical Study by Henriette Louise Möllmann, Eman Alhammadi, Soufian Boulghoudan, Julian Kuhlmann, Anica Mevissen, Philipp Olbrich, Louisa Rahm, Helmut Frohnhofen

“…MethodsWe performed both pre- and postoperative assessments in patients of 4 different surgical departments who are older than 70 years. …”
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Association of preoperative cognitive frailty with postoperative complications in older patients under general anesthesia: a prospective cohort study by Jiamin Fang, Hao Liang, Muxin Chen, Yidi Zhao, Lin Wei

“…Objective To investigate the effect of preoperative CF on postoperative complications in older patients. Methods This prospective cohort study was conducted among 253 patients aged 60–85 years, who underwent elective orthopedic and abdominal surgery (with a postoperative hospital stay of ≥ 3 days) at the Second Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2023 to November 2023. …”
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Cell salvage and donor blood transfusion during cesarean section: A pragmatic, multicentre randomised controlled trial (SALVO). by Khalid S Khan, Philip A S Moore, Matthew J Wilson, Richard Hooper, Shubha Allard, Ian Wrench, Lee Beresford, Tracy E Roberts, Carol McLoughlin, James Geoghegan, Jane P Daniels, Sue Catling, Vicki A Clark, Paul Ayuk, Stephen Robson, Fang Gao-Smith, Matthew Hogg, Doris Lanz, Julie Dodds, SALVO study group

“…Cell salvage may reduce this requirement.<h4>Methods and findings</h4>We conducted a pragmatic randomised controlled trial (at 26 obstetric units; participants recruited from 4 June 2013 to 17 April 2016) of routine cell salvage use (intervention) versus current standard of care without routine salvage use (control) in cesarean section among women at risk of haemorrhage. …”
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