Endothelial function/damage markers and NGAL – intraoperative assessment in blood specimens obtained from different sampling sites during open repair of abdominal aortic aneurysm by Michał Kokot, Grzegorz Biolik, Anna Kokot, Leszek Kędzierski, Tadeusz Fojt, Damian Ziaja, Krzysztof Ziaja, Jan Duława

“…Introduction: The aim of the study was to investigate the dynamics of changes in the concentrations of neutrophil gelatinase-associated lipocalin (NGAL), an acute kidney injury biomarker, as well as endothelial function/damage markers including P-selectin, intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1) and the von Willebrand factor (vWf) in blood specimens obtained from different sampling sites during open abdominal aortic aneurysm (AAA) repair. Material and methods: Thirty-three patients qualified for elective open repair (ORe) were enrolled in the study. …”
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Association between preoperative oxygen reserve index and postoperative pulmonary complications: a prospective observational study by Sangho Lee, Halin Hong, Hyojin Cho, Sang-Wook Lee, Ann Hee You, Hee Yong Kang, Sung Wook Park, Mi Kyeong Kim, Jeong-Hyun Choi

“…To evaluate whether a degree of increase in the ORi during preoxygenation for general anesthesia is associated with the occurrence of postoperative pulmonary complications (PPCs). Methods We enrolled 154 patients who underwent preoperative pulmonary function tests and were scheduled for elective surgery under general anesthesia. …”
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RETRACTED: High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy by Tengteng Li, Tengteng Li, Jiajia Fei, Huihui Yu, Xingxing Wang, Jingjing Bai, Fucai Chen, Dan Li, Zongzhi Yin, Zongzhi Yin, Zongzhi Yin

“…In this study, we examined the expression of HIF-1α and TREK1 proteins in GDM uterine and investigated whether high glucose levels are involved in the regulation of human uterine smooth muscle cells (HUSMCs) contraction through TREK1, and verified the role of HIF-1α in this process.MethodsCompared the uterine contractility between GDM and normal patients undergoing elective lower segment cesarean section. …”
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The DEXA-CORT trial: study protocol of a randomised placebo-controlled trial of hydrocortisone in patients with brain tumour on the prevention of neuropsychiatric adverse effects c... by Elisabeth F C van Rossum, Amir H Zamanipoor Najafabadi, Wouter A Moojen, Nienke R Biermasz, Wouter R van Furth, Onno C Meijer, Clemens M F Dirven, Anne-Sophie C A M Koning, Djaina D Satoer, Christiaan H Vinkers, Rishi D S Nandoe Tewarie, Alberto M Pereira

“…The DEXA-CORT trial aims to reactivate the MR using cortisol to reduce neuropsychiatric adverse effects of dexamethasone treatment.Methods and analysis The DEXA-CORT study is a multicentre, randomised, double-blind, placebo-controlled trial in adult patients who undergo elective brain tumour resection treated perioperatively with high doses of dexamethasone to minimise cerebral oedema. 180 patients are randomised between treatment with either two times per day 10 mg hydrocortisone or placebo during dexamethasone treatment. …”
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Dermabond-adhesive glue versus polypropylene sutures for cesarean section-skin closure by Zainab Abdul Ameer Jaafar, Zhanslu Sarkulova, Ainur Tokshilykova, Ibrahim A. Abdelazim, Marat Sarkulov, Yersulu Sagidanova, Farida Balmaganbetova, Ainur Donayeva

“…OBJECTIVES: To compare the Dermabond-adhesive glue versus polypropylene sutures for cesarean section (CS) skin closure. MATERIAL AND METHODS: One hundred women admitted for elective CSs (ECSs) were randomized into two groups; Dermabond group including women underwent CS-skin closure using Dermabond-adhesive glue and polypropylene group including women underwent CS-skin closure using polypropylene sutures. …”
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Long-Term Outcomes of Extent of Revascularization in Complex High Risk and Indicated Patients Undergoing Impella-Protected Percutaneous Coronary Intervention: Report from the Roma-... by Francesco Burzotta, Giulio Russo, Flavio Ribichini, Anna Piccoli, Domenico D’Amario, Lazzaro Paraggio, Leonardo Previ, Gabriele Pesarini, Italo Porto, Antonio Maria Leone, Giampaolo Niccoli, Cristina Aurigemma, Diana Verdirosi, Filippo Crea, Carlo Trani

“…However, the impact of more complete revascularization during Impella-protected PCI in CHIP has not been reported. Methods. A total of 86 CHIP undergoing elective PCI with Impella 2.5 or Impella CP between April 2007 and December 2016 from 2 high volume Italian centers were included. …”
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Effect of propofol and ciprofol in patients undergoing bronchoscopy: protocol for a double-blind, randomised controlled trial by Fang Chen, Cheng Li, Dongliang Li, Jinxuan Tang, Jiayu Huang

“…This study aims to compare the impact of equivalent effective doses of propofol and ciprofol on haemodynamic changes in patients undergoing bronchoscopy under general anaesthesia.Methods This prospective, double-blind, randomised, controlled clinical trial will recruit 250 patients aged 18–80 years scheduled for elective bronchoscopy under general anaesthesia. …”
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Renal Outcomes With Renin-Angiotensin System Blockers After Unilateral Nephrectomy by Sehun Lee, Sungbin Yoon, Sungmi Kim, Hojin Jeon, Kyeongho Lee, Hye Ryoun Jang, Jung Eun Lee, Wooseong Huh, Junseok Jeon

“…We aimed to evaluate the effect of RAS blockers immediately after unilateral nephrectomy on renal adaptation. Methods: This single-center retrospective cohort study included 580 patients who underwent elective unilateral nephrectomy between 2010 and 2020 and had preexisting hypertension with antihypertensive medications. …”
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Clinical, functional and neuropsychological status of joint replacement patients by Akhsarbek H. Dzhigkaev, Anastasia M. Tynterova, Ivan I. Kozenkov, Eldar V. Khaibulin, Elena V. Trofimova, Konstantin Y. Popadin, Konstantin V. Gunbin, Andrey G. Goncharov

“…The objective was to assess the clinical, functional and neuropsychological status of patients undergoing total knee or hip replacement. Material and methods The study included 448 patients admitted for elective surgery of total knee or hip replacement at the Department of Traumatology and Orthopedics of the Federal Center for High Medical Technologies (CHMT, Kaliningrad Region). …”

Rescue transventricular off-pump mitral valve repair with artificial neochords for acute mitral regurgitation due to postinfarction papillary muscle rupturePerspectiveCentral Messa... by Mindaugas Budra, MD, Vilius Janušauskas, MD, PhD, Aleksejus Zorinas, MD, PhD, Diana Zakarkaitė, MD, PhD, Audrius Aidietis, MD, PhD, Robertas Samalavičius, MD, PhD, Kęstutis Ručinskas, MD, PhD

“…All 3 patients underwent an elective MV reoperation via conventional approach. …”
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Invasively Measured Aortic Systolic Blood Pressure and Office Systolic Blood Pressure in Cardiovascular Risk Assessment in CKD by Christian D. Peters, Kevin K.W. Olesen, Esben Laugesen, Michael Mæng, Hans Erik Bøtker, Per L. Poulsen, Niels Henrik Buus

“…This study examined whether invasively measured aortic systolic BP improved outcome prediction beyond risk prediction by conventional cuff-based office systolic BP in patients with and without chronic kidney disease (CKD). Methods: In a prospective, longitudinal cohort study, aortic and office systolic BPs were registered in patients undergoing elective coronary angiography (CAG). …”
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Intraoperative methadone for postoperative pain in adult patients undergoing tonsillectomy—a randomised controlled trial by Michael Bøndergaard, Peter Gaarsdal Uhrbrand, Tutku Karaca, Marianne Rhode, Thomas Kjærgaard, Rene Thunberg Svendsen, Tejs Ehlers Klug, Lone Nikolajsen, Kristian Dahl Friesgaard

“…This study hypothesised that methadone would provide superior postoperative pain relief and reduced opioid consumption compared with fentanyl. Methods: A total of 120 adult patients undergoing elective bilateral tonsillectomy were randomly allocated to receive either methadone (0.2 mg kg−1; n=62) or fentanyl (3 μg kg−1; n=58) after anaesthesia induction. …”
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High-altitude adaptation as a protective factor against postoperative pulmonary complications in liver resection: a prospective matched cohort study by Qingyong Luo, Yu Zhang, Shiyao Gu, Li liu, Si Zeng, Qian Lei

“…Abstract Background High-altitude adaptation (HAA), induced by chronic hypoxia, has clinically significant cardioprotective effects; however, its impact on postoperative pulmonary complications (PPCs) in patients undergoing liver resection remains uncertain. Methods We conducted a single-center prospective matched cohort study enrolling 292 consecutive patients undergoing elective liver resection. …”
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Bicuspid Valve Aortopathy: Is It Reasonable to Define a Different Surgical Cutoff Based on Different Aortic Wall Mechanical Properties Compared to Those of the Tricuspid Valve? by Pasquale Totaro, Alessandro Caimi, Giulia Formenton, Martina Musto, Martina Schembri, Simone Morganti, Stefano Pelenghi, Ferdinando Auricchio

“…Background: In this study, we examined and compared ex vivo mechanical properties of aortic walls in patients with bicuspid (BAV) and tricuspid (TAV) aortic valve aortopathy to investigate if the anatomical peculiarities in the BAV group are related to an increased frailty of the aortic wall and, therefore, if a different surgical cutoff point for ascending aortic replacement could be reasonable in such patients. Methods: Ultimate stress tests were performed on fresh aortic wall specimens harvested during elective aortic surgery in BAV (n. 33) and TAV (n. 77) patients. …”
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Implementing an enhanced recovery from surgery pathway to reduce hospital length of stay for primary hip or knee arthroplasty: a budget impact analysis by Melanie Lloyd, Zanfina Ademi, Ian A. Harris, Justine Naylor, Peter Lewis, Richard de Steiger, Rachelle Buchbinder, Anthony Wan, Ilana N. Ackerman

“…This study aims to determine the impact on healthcare costs of implementing an enhanced short-stay model of care (ESS-MOC) for arthroplasty at a national level. Methods A budget impact analysis was conducted for the years 2023–2030 in the setting of Australian publicly and privately funded hospitals performing hip or knee arthroplasty. …”
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Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry by Nikolić Aleksandra, Krnjajić Mina, Marković Velimir, Barišić Goran, Dimitrijević Ivan, Krivokapić Zoran

“…The aim of this study was to establish a collection of a consensus dataset capturing surgical treatment of CRC at multiple public hospitals across Serbia and estimate outcome in CRC patients subjected to surgical treatment in the period 2010–2014. Methods. The study encompassed all 52 public CRC surgical units in Serbia. …”
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Effect of low-dose esketamine on postoperative quality of recovery in total laparoscopic hysterectomy: a randomized controlled trial by Jing Zhang, Zheng Niu, Ting Wang, Lianya Yu, Xinyi Ren, Shurui Zhang, Yuwei Zhu, Dunyi Qi

“…Abstract Purpose To investigate the effect of intraoperative low-dose esketamine administered at anesthesia induction on postoperative quality of recovery in total laparoscopic hysterectomy. Patients and methods One-hundred six female patients scheduled for elective total laparoscopic hysterectomy were randomly divided into saline group (group P) and esketamine group (group S). …”
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Adherence to Clinical Quidelines on Preoperative Assessment and Correction of Cardiovascular Risk in Non-cardiac Surgery by M. D. Nigmatkulova, E. B. Kleymenova, L. P. Yashina, V. A. Otdelenov, S. A. Payushchik, O. D. Konova, D. A. Sychev

“…To study physicians' level of adherence to ESC/ESA clinical guidelines for preoperative assessment and perioperative management of patients.Material and methods. A retrospective observational study included 102 patients admitted to Moscow general hospital from 01.03.2019 to 30.06.2018 for elective surgery. …”
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The oxytocin-oxytocin receptors system — a new pathogenetic mechanism in the development of diabetic phenotype of heart failure with preserved ejection fraction in women by A. D. Starchenko, Yu. V. Liskova, A. A. Stadnikov

“…To determine the pathogenetic role of the oxytocinergic system in the development of myocardium structural and functional changes in women with heart failure with preserved ejection fraction (HFpEF) associated with type 2 diabetes mellitus (DM2T) (diabetic phenotype of HFpEF).Material and methods. The study included 60 women aged 67.0±4.9 years with HFpEF stage I-IIA, FC I-III, 30 of them had DM2T who were admitted for elective coronary artery bypass grafting. …”
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Risk factors and outcomes of gastrointestinal bleeding in patients with stable coronary artery disease: data from the observational registry of long-term antithrombotic therapy REG... by A. L. Komarov, O. O. Shakhmatova, V. V. Korobkova, E. S. Novikova, E. V. Guskova, E. B. Yarovaya, T. V. Balachonova, A. G. Shuleshova, E. P. Panchenko

“…To optimize the upper gastrointestinal bleeding (UGIB) risk scale in patients Material and methods. The UGIB risk scale was developed based on the with chronic coronary artery disease (CAD) receiving long-term antiplatelet therapy. prospective REGistry of long-term AnTithrombotic TherApy-1 REGATTA-1(ClinicalTrials.gov Identifier: NCT04347200). …”
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