High and low body mass index increases the risk of short-term postoperative complications following total shoulder arthroplasty by Salvatore Capotosto, MD, Matthew Kim, MD, Kenny Ling, MD, Alireza Nazemi, MD, Ryan Tantone, MD, Elizabeth Wang, MD, David E. Komatsu, PhD, Edward D. Wang, MD

“…Therefore, this study aims to better understand the impact of BMI on 30-day post-TSA outcomes by performing a comprehensive risk stratification based on BMI using a large national database. Methods: All patients undergoing TSA, both anatomic and reverse, between 2015 and 2019 were queried from the American College of Surgeons National Surgical Quality Improvement Program database. …”
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Feasibility, safety, and outcome of fetoscopic endoluminal tracheal occlusion for severe congenital diaphragmatic hernia at a low case-load center: one center's experience by Saud Alshanafey, Wesam I. Kurdi, Maha Tulbah, Rubina MA Khan, Nada Al Sahan, Maisoon Al Mugbel, Fahad Al-Hazzani, Gawaher Almutairi, Ala Jebreel, Maha Al-Nemer

“…SETTING: Tertiary health care center. PATIENTS AND METHODS: 18–45 years old, with single fetuses diagnosed with left severe CDH (lung-head ratio <1 measured between 27–29 weeks of gestational age (GA) and liver up or observed/expected lung-to-head ratio <25%, normal echocardiogram and karyotype were included. …”
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The Adjunctive Effect of Quercetin on Postoperative Pain Management Following Cesarean Section: A Randomized Controlled Study by Mohamed Elmokadem E, Khaled Abou El Fadl D, Bassiouny AM, Mahmoud MMAE, Samy M, El Said NO

“…This study aimed to assess the efficacy of preoperative Quercetin administration on acute post-operative pain following cesarean section.Patients and Methods:  In this prospective, double-blinded, randomized controlled trial, 80 patients undergoing elective cesarean section under spinal anaesthesia were randomly allocated to receive either 500 mg oral Quercetin (n=40) or matching placebo (n=40) one hour before surgery. …”
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Effect of opioid-free anaesthesia on postoperative delirium in elderly patients undergoing gastrointestinal surgery: study protocol for a single-centre, prospective, randomized con... by Yuehan Du, Mengjie Liu, Xiaoling Yang, Jianbo Wu, Xiaojun Gao, Qiuyue Liu, Lina Chen, Xiaxuan Sun, Min Zhang, Yongtao Sun

“…This study aims to investigate the effects of OFA on the development of POD in elderly patients following gastrointestinal surgery. Methods and analysis This single-centre, prospective, randomized controlled trial will be conducted at the First Affiliated Hospital of Shandong First Medical University, China. …”
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The impact of ultrasound-guided erector spinae plane block combined with paravertebral block on postoperative rebound pain following thoracoscopic lobectomy by Yihang He, Dongxu Chen, Youbo Zuo, Jing Lin

“…Given that the erector spinae plane block (ESPB) may modulate the incidence of rebound pain through its mechanism of local anesthetic diffusion into the paravertebral space, this study sought to evaluate whether combining TPVB with ESPB could effectively reduce postoperative rebound pain in VATS patients.MethodsA total of 110 patients scheduled for elective video-assisted thoracoscopic lobectomy were enrolled and randomly allocated via a random number table to either the TPVB group (Group P, n = 55) or the TPVB combined with ESPB group (Group PE, n = 55). …”
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Comparative efficacy and safety of nalbuphine and hydromorphone in painless colonoscopy techniques: a randomized controlled trial by Chunliu Hou, Siming Zhang, Yuqing Zhu, Guochun Wen, Guoran Wang, Jinxiang Dai, Fei Xu, Chunjie Li, Huiyi Chen, Di Wang, Qingqing Han, Xuesen Su, Wenjie Zhang, Shouyuan Tian, Yan Li

“…This study compared the efficacy and safety of nalbuphine and hydromorphone in improving patient comfort and maintaining hemodynamic stability during elective colonoscopy. Methods This prospective, randomized, double-blinded controlled trial included 72 adult patients (aged 18–65) who underwent sedation colonoscopy. …”
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Evidence-based medical procedures to optimise caesarean outcomes: an overview of systematic reviewsResearch in context by Virginia Diaz, Celina Gialdini, Mónica Chamillard, Julia Pasquale, Guillermo Carroli, Maria Regina Torloni, Ana Pilar Betran

“…We conducted an overview of systematic reviews (SRs) of randomised controlled trials (RCTs) to summarise the evidence on medical procedures used in CS. Methods: Searches were conducted in Cochrane Database of Systematic Reviews, PubMed, EMBASE, LILACSs and CINAHL without date or language restrictions from database inception to January 31, 2024, with an updated search performed on January 24, 2025. …”
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Efficacy of opioid-free anesthesia in reducing postoperative nausea and vomiting following gynecological laparoscopic surgery: a randomized controlled trial by Yanan Shen, Yanan Shen, Yuanyuan Wu, Yuanyuan Wu, Qianqian Tang, Qianqian Tang, Yilong Wang, Yilong Wang, Wei Ma, Wei Ma, Jianwei Wang, Jianwei Wang

“…This study aimed to evaluate the efficacy of OFA in reducing PONV and its impact on postoperative recovery.MethodsThis randomized, double-blind, controlled trial enrolled 92 female patients undergoing elective gynecological laparoscopic surgery. …”
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Dexmedetomidine versus Dexamethasone as an Adjuvant to Ropivacaine in Transversus Abdominis Plane Block in Infraumbilical Surgeries for Postoperative Analgesia: A Randomised Clinic... by Anupama Kumari, Aarjvi Patel, Payal Berawala, Sara Mary Thomas

“…The secondary objective was to compare postoperative haemodynamic changes and side effects. Materials and Methods: In this randomised double-blinded prospective clinical study, conducted in the Department of Anaesthesia, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (SBKS MIRC), Piparia, Vadodara, Gujarat, India from March 2023 to September 2024. 80 patients of American Society of Anaesthesiologists (ASA) I and II, aged 18-60 years, undergoing elective infraumbilical surgeries (open abdominal hysterectomy and open bilateral inguinal hernia repair) under spinal anaesthesia were randomly allocated into two groups of 40 patients each. …”
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Comparative analysis of the functional status of hip joints before total hip replacement in patients with ankylosing spondylitis, rheumatoid arthritis and coxarthrosis: preliminary... by A. O. Dubinin, A. E. Khramov, T. V. Dubinina, E. V. Ilinykh, E. I. Byalik

“…All patients underwent elective THA between 1998 and 2020. Among AS patients, men (80.6%) predominated. …”
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Comparison of the Effects of Two Different Low-Doses of Isobaric Bupivacaine on Intraoperative Hemodynamics under Spinal Anaesthesia during Caesarean Section: A Randomized Controll... by Aysenur Dostbil, Canan Atalay, Ilker Ince, Mehmet Aksoy, Ozgur Ozmen, Kamber Kasali, Omer Erkan Yapca, Tugberk Kucun, Ayse Nur Aksoy, Gamze Nur Cimilli Senocak

“…Background: The objective of this study was to conduct a randomized controlled trial in order to examine the hemodynamic impacts of two different doses of intrathecal isobaric bupivacaine (5 mg and 7 mg) when combined with 15 µg fentanyl in the context of patients undergoing caesarean section under combined spinal epidural anesthesia. Methods: Eighty patients with American Society of Anesthesiologists physical status I and II, aged between 16–50 years, who would undergo elective caesarean section under combined spinal epidural anaesthesia were randomly allocated to Group A and Group B (n = 40, for each group). …”
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Proton Pump Inhibitor Use Following Esophageal Variceal Ligation and Its Impact on Clinical Outcomes: Real-World Data from the TriNetX Global Collaborative Network by Nisar Amin, Harleen Chela, Muhammad Faisal Mubarak, Mark Ayoub, Ebubekir Daglilar

“…This study utilizes the TriNetX global health research network to evaluate the outcomes of PPI use following elective EVL for primary prophylaxis. <b>Methods:</b> This retrospective cohort study was conducted using the TriNetX database to evaluate adult patients with cirrhosis and esophageal varices who underwent EVL for primary prophylaxis. …”
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Influence of open surgical and endovascular abdominal aortic aneurysm repair on clot quality assessed by ROTEM® test by Šarac Momir, Marjanović Ivan, Bezmarević Mihailo, Šarac Sanja, Milić Rade, Obradović Slobodan, Tomić Aleksandar

“…The aim of this study was to compare the impact of OR and EVAR of AAA on clot quality assessed by rotational thromboelastometry (ROTEM®) tests. Methods. The study included 40 patients who underwent elective AAA surgery and were devided into two groups (the OR and the EVAR group - 20 patients in each group). …”
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An impact of neutrophil extracellular traps to the prothrombotic state and tumor progression in gynecological cancer patients by E. V. Slukhanchuk, V. O. Bitsadze, A. G. Solopova, J. Kh. Khizroeva, N. D. Degtyareva, D. V. Shcherbakov, J.-C. Gris, I. Elalamy, A. D. Makatsariya

“…In addition, NET-related effect on tumor progression and metastasis has been actively studied.Aim: to evaluate NET-related procoagulant activity in gynecological cancer patients.Materials and Methods. From April 2020 to October 2022, a prospective controlled interventional non-randomized study was conducted with 120 women. …”
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Expression and Correlation of Complement C3 and C4 in Serum and Maternal-Fetal Interface in Patients with Unexplained Recurrent Spontaneous Abortion: A Prospective Cohort Study by Zhengxin Zhou, Huixia Xie, Miao Liu, Ruopeng Li, Wenjing Jiang, Yan Zheng, Qun Lv

“…Background: In this study, we sought to detect the expression of complement C3 and C4 in serum and maternal-fetal interface in patients with unexplained recurrent spontaneous abortion, and analyze their correlation, in order to explore the clinical significance and role of C3 and C4 in unexplained recurrent spontaneous abortion. Methods: In a prospective cohort study, products of conception of 20 women who underwent curettage due to unexplained recurrent spontaneous abortion in the Department of Obstetrics and Gynecology at the Sichuan Provincial People’s Hospital from December 2021 to December 2022 were chosen as the case group, and 23 healthy early-pregnancy women who underwent elective abortion due to personal reasons during the same period were chosen as the control group. …”
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Direct Gallbladder Extraction versus Endobag Extraction during Laparoscopic Cholecystectomy: A Prospective Observational Study by Swathy Elangovan, K Vivekananda Subramania Nathan, R Sivamarieswaran, M Reegan Jose

“…A total of 60 patients undergoing elective LC were randomised into two groups: Group A (direct extraction) and Group B (endobag extraction). …”
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Long-term impact of diabetes on mortality in patients undergoing unprotected left main PCI: a propensity score-matched analysis from the BIA-LM registry by Paweł Kralisz, Emil Julian Dąbrowski, Sławomir Dobrzycki, Wiktoria Urszula Kozłowska, Patrycja Oliwia Lipska, Konrad Nowak, Kamil Gugała, Przemysław Prokopczuk, Grzegorz Mężyński, Michał Święczkowski, Marcin Kożuch

“…This observational study, based on the largest single-center registry of LMCA PCI in Poland, evaluated the impact of diabetes on long-term survival following PCI in a real-world setting. Methods We retrospectively analyzed 998 patients who underwent LMCA PCI between December 27, 2007, and February 21, 2022. …”
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Comparison of Oliceridine and Morphine in Postoperative Analgesia in Laparoscopic Total Hysterectomy, a Randomized Double-Blind Controlled Trial by Duan J, Wang X, Hou C, Yu T, Ju X, Wang S

“…Jinjuan Duan,&amp;ast; Xing Wang,&amp;ast; Chengjing Hou, Tong Yu, Xia Ju, Shengbin Wang Department of Anesthesiology, Affiliated Anqing Medical Centre of Anhui Medical University, Affiliated Anqing Hospital of China Pharmaceutical University, Anqing Municipal Hospital, Anqing, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Xia Ju, Department of Anesthesiology, Affiliated Anqing Medical Centre of Anhui Medical University, Affiliated Anqing Hospital of China Pharmaceutical University, Anqing Municipal Hospital, No. 87 Tianzhushan East Road, Anqing, 246000, People’s Republic of China, Tel +86-13685563136, Email alcon2006@126.com Shengbin Wang, Department of Anesthesiology, Affiliated Anqing Medical Centre of Anhui Medical University, Affiliated Anqing Hospital of China Pharmaceutical University, Anqing Municipal Hospital, No. 87 Tianzhushan East Road, Anqing, 246000, People’s Republic of China, Tel +86-13955665151, Email shbw1965@126.comPurpose: Compare the analgesic efficacy and safety profiles of oliceridine and morphine in patient-controlled intravenous analgesia (PCIA) after laparoscopic total hysterectomy.Materials and Methods: This prospective, double-blind trial randomly allocated 60 patients undergoing elective laparoscopic total hysterectomy in a 1:1 ratio to receive either oliceridine (group O) or morphine (group M) via PCIA. …”
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Trends, Patient Outcomes, and Resource Utilization Associated with Surgical Staplers During Robotic Sleeve Gastrectomy by Pan IW, Siddiqui ZA

“…This study evaluates the trend, the effectiveness (outcomes) and efficiency (resource utilization) of different types of surgical staplers used in robotic sleeve gastrectomy (RSG).Patients and Methods: This was a retrospective observational cohort study analyzing data from the PINC AI™ Healthcare Data database. …”
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Oxycodone for analgesia in children undergoing endoscopic retrograde cholangiopancreatography: a randomized, double-blind, parallel study by Wei Ji, Wei Ji, Liping Sun, Liping Sun, Yue Huang, Yue Huang, Jie Bai, Jie Bai, Jijian Zheng, Jijian Zheng, Kan Zhang, Kan Zhang

“…In this study, we compared the analgesic and anti-inflammatory effects of oxycodone and fentanyl in children undergoing ERCP.MethodsA single-center, randomized, double-blind study was conducted at a tertiary care hospital affiliated with Shanghai Jiao Tong University. …”
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