Effects of esketamine combined with thoracic paravertebral block on postoperative early sleep in patients undergoing thoracoscopic lobectomy by LI Wenyan, ZHANG Yong, ZHANG Chen, SHI Li

“…Objective To observe the effects of continuous intravenous infusion of esketamine combined with thoracic paravertebral nerve block (TPVB) on postoperative early sleep, analgesia, and recovery quality in patients undergoing thoracoscopic lobectomy. Methods A total of 76 patients scheduled for elective thoracoscopic lobectomy at Nanjing First Hospital from January 2023 to January 2024 were randomly divided into two groups: the control group (C group) and the esketamine group (E group), with 38 patients in each group. …”
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UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): what does analysis of linked, routinely collected national datasets tell us about mid–late term revision risk after knee r... by Andrew Judge, Sarah R Kingsbury, Nigel K Arden, Rafael Pinedo-Villanueva, Lindsay K Smith, Cesar Garriga, Antonella Delmestri, Martin Stone

“…Objective To identify patients at risk of mid-late term revision of knee replacement (KR) to inform targeted follow-up.Design Analysis of linked national datasets from primary and secondary care (Clinical Practice Research Datalink (CPRD GOLD), National Joint Registry (NJR), English Hospital Episode Statistics (HES) and Patient Reported Outcome Measures (PROMs)).Participants Primary elective KRs aged ≥18 years.Event of interest Revision surgery ≥5 years (mid–late term) postprimary KR.Statistical methods Cox regression modelling to ascertain risk factors of mid–late term revision. …”
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Development and evaluation of a national administrative code-based system for estimation of hospital-acquired venous thromboembolism in Ireland by Barry Kevane, Fionnuala Ní Áinle, Richard Daly, Ciara Kirke, Deirdre Lynch, Emer Gallagher, Therese Dalchan, Jacqui Curley, Ruth Buckley, Maeve P Crowley, Ann Marie O’Neill

“…The Irish Health Service Executive (HSE) launched a National Key Performance Indicator (KPI) in 2019 for monitoring HA-VTE rates using the Australian Modification of ICD-10 (ICD-10-AM) codes.Objectives This study aims to (1) describe the development of the national HSE KPI and determine the national HA-VTE occurrence rate per 1000 discharges in 2022; (2) assess the contribution of each VTE ICD-10-AM code to the national HA-VTE figure; (3) estimate the positive predictive value (PPV) of the HSE KPI against true HA-VTE, in a single large tertiary (Irish Model 4) hospital.Methods A retrospective observational study used national data from Irish publicly funded acute hospitals, focusing on discharges from 2022. …”
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Cerebrospinal Fluid Presepsin as a Marker of Nosocomial Infections of Central Nervous System by S. A. Abudeyev, K. V. Kiselyov, O. V. Parinov, Yu. D. Udalov, M. A. Zabelin, A. S. Samoylov, K. A. Popugayev

“…The timely diagnosis of NI-CNS is a relevant problem and the search for new reliable markers of NI-CNS is an important issue.MATERIAL AND METHODS The prospective observational study consisted of two parts. …”
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Perioperative diltiazem or nitroglycerin in on-pump coronary artery bypass: A systematic review and network meta-analysis. by Yirui Hu, Xinbei Yang, Li Zhang, Xianren Wu, Anastasia Yian Liu, Joseph A Boscarino, H Lester Kirchner, Alfred S Casale, Xiaopeng Zhang

“…The current systematic review and network meta-analysis aims to summarize the data from all available randomized clinical trials of perioperative continuous intravenous infusion of diltiazem and/or nitroglycerin in patients undergoing on-pump CABG in order to define and compare their roles in graft spasm prevention and their impacts on perioperative outcomes.<h4>Methods</h4>We searched Ovid Medline, PubMed, CINAHL, Google Scholar and Cochrane Center for randomized controlled trials that reported outcome effects of perioperative continuous intravenous infusion of diltiazem and/or nitroglycerin in patients undergoing elective on-pump CABG. …”
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Medical Students&rsquo; Knowledge and Perceptions of Herbal Medicine in Saudi Arabia: Should Medical Schools Take Immediate Action? by Almech M, Alissa A, Baghdadi RA, Abujamai JZ, Hafiz W, Alwafi H, Shaikhomer M, Alshanberi AM, Alshareef MH, Alsanosi SM

“…This study aims to evaluate medical students’ knowledge and perceptions regarding herbal medicine in Saudi Arabia.Methods: A cross-sectional study was conducted among medical students in three medical colleges in Saudi Arabia over a six-month period from 1 February to 31 July 2024. …”
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Cardiovascular outcomes in metabolically healthy Asian-American population with obesity (18–44 years): Insights from the National Inpatient Sample by Rupak Desai, Avilash Mondal, Boney Lapsiwala, Venkata Balaji Chenna, Pratik Rajpopat, Vaidehi Mendpara, Athri Kodali, Amritha R. Nair, Ayodya Perera, Subramanian Gnanaguruparan

“…However, in-hospital outcomes among young, metabolically healthy (MHO) Asians with obesity have not been explored. Methods: This was a retrospective cohort study that utilized 2019 National Inpatient Sample (NIS) database to identify hospitalizations of metabolically healthy young (18–44 years) Asian-Americans/Pacific Islanders (AA/API). …”
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Effects of single subanesthetic dose of oxycodone on pain and Th1/Th2 balance in patients after radical mastectomy by QU Na，ZHAO Xiaohong，NI Qiang

“…Objective To compare the effects of oxycodone and fentanyl on postoperative pain relief，immune balance of T-helper cells（Th），and adverse reactions in radical mastectomy. Methods A total of 120 female patients whounderwent elective radical mastectomy at Shanghai Public Health Clinical Center between December 2021 and January2024 were selected for this study. …”
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Noninferiority of 0.25% versus 0.375% Ropivacaine in Popliteal Sciatic and Saphenous Nerve Blocks for Analgesia After Foot and Ankle Surgery: A Randomized Self-Paired Noninferiorit... by Wu L, Xi C, Lei G, Li H, Yin Y, Wan M, Wu H, Wang Y, Hu C, Wang G

“…Hence, we hypothesized that the analgesic effect of 0.25% ropivacaine would be noninferior to that of 0.375% ropivacaine at the same volume and would reduce the degree of weakness.Patients and Methods: In this randomized, double-blind, self-paired, noninferiority trial, 31 patients who were scheduled for similar, elective, bilateral foot and ankle surgeries under general anesthesia combined with popliteal sciatic and saphenous nerve blocks were enrolled. …”
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Four-Year Analysis of a Five-Year Prospective Multicenter Study Assessing Radiographic Recurrence and Patient Outcomes Following Triplanar Tarsometatarsal Arthrodesis with Early We... by Daniel C. Farber MD, Dane K. Wukich MD, Robert D. Santrock MD, Abdi Raissi MD, Avneesh Chhabra MD, Jennifer Koay MD, Paul Dayton DPM, Jody P. McAleer DPM, Robert Taylor DPM, Dan Hatch DPM, Deidre Kile BS

“…This study evaluated the clinical, radiographic, and patient-reported outcomes in patients undergoing instrumented triplanar 1st TMT arthrodesis (TMTA) with a biplanar plating system and protected early weightbearing. Methods: This is a prospective multicenter study that will continue for 60 months post-operatively. …”
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Evaluation of Perinatal Outcome in Women with Impaired Glucose Homeostasis During Pregnancy by Neha SAHAY, Felice FAIZAL

“…It is controversial whether maternal hyperglycemia less severe than in diabetes is associated with increased risk of adverse pregnancy outcome or not. Materials and methods: All women were subjected to Glucose Challenge Test(GCT) with 50 gram glucose either at first visit or between 24-28 weeks on the basis of risk profile. …”
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Patients’ anesthesia preferences for Cesarean delivery: exploring the role of personality beliefs in spinal vs. General anesthesia by Esra Turunc, Sezgin Bilgin, Sevda Akdeniz, Ozgur Komurcu, Leman Tomak, Yasemin Burcu Ustun, Ersin Koksal, Burhan Dost

“…Abstract Background This study aimed to compare the personality belief scores of patients who chose either general or spinal anesthesia during cesarean delivery (CD) and explore the relationship between personality beliefs, and anxiety levels. Methods This prospective study included expecting mothers, aged 18–45 years, who were classified as ASA II-III, scheduled for elective CD. …”
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Efficacy of Bilateral Transverse Abdominis Plane Block and Ilioinguinal Iliohypogastric Nerve Block for Post Lower Segment Caesarean Section Pain Relief: A Randomised Clinical Stud... by Jigisha Bharatbhai Mehta, Gayatri Vasagadekar, Sara Mary Thomas

“…Aim: To compare the efficacy of bilateral Transverse Abdominis Plane block (TAP) and Ilioinguinal Iliohypogastric block (II-IH) for postcaesarean section pain relief. Materials and Methods: A randomised clinical study was conducted at Dhiraj Hospital, Piparia, Vadodara, Gujarat, India, on 60 pregnant women, aged between 18 to 45 years, who were posted for elective Lower Segment Caesarean Section (LSCS). …”
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Effect of superficial cervical plexus nerve block with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patie... by Xiaoyu Kang, Caifen Li, Liuyu Lu, Xiaotong Qin, Yonghao Wang, Yang Lu, Li Ma, Shaoliang Zhu, Zheng Gong

“…Abstract Objective To investigate the effect of ultrasound-guided bilateral superficial cervical plexus nerve blocks with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patients undergoing radical thyroid cancer surgery under general anesthesia with nerve monitoring without muscarinic maintenance. Methods A total of 140 patients undergoing elective radical thyroid cancer surgery were randomly divided into four groups, with 35 cases in each group: general anesthesia alone group (Group C), general anesthesia + Ropivacaine group (Group R), general anesthesia + Ropivacaine combined with dexmedetomidine group (Group R1), and general anesthesia + Ropivacaine combined with dexamethasone group (Group R2). …”
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Effects of remimazolam, cipepofol and propofol on circulation during induction period of general anesthesia by ZHANG Qing, HONG Hong, AN Jing, JI Muhuo, PENG Hui

“…Objective To observe the effects of remimazolam, cipepofol, and propofol on hemodynamics, blood glucose, and lactate levels during general anesthesia induction. Methods A total of 126 elective surgery patients at the Second Affiliated Hospital of Nanjing Medical University from August to November 2023, undergoing non-cardiothoracic and neurosurgical procedures under general anesthesia, were included. …”
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Comparative Study of Intervenous Granisetron against Ondansetron in Preventing Postoperative Nausea Vomiting in Patients undergoing General Anaesthesia: A Double-blinded Randomised... by Sufala Sunil Vishwasrao, Sunil Mhatarba Vishwasrao, Amar Nagesh Kumar

“…Granisetron and Ondansetron in preventing PONV in patients undergoing general anaesthesia in a tertiary care hospital in Tamil Nadu, India. Materials and Methods: A double-blind, randomised controlled trial was conducted at Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Madhurantagam, Tamil Nadu, India, from December 2021 to March 2023 involving 66 patients aged 18-65 years, scheduled for elective surgeries under general anaesthesia. …”
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Risk Index for Predicting Supplemental Oxygen Requirement upon Discharge from Postanesthetic Care in Adult Spinal Surgery Patients: A Single-Center Study by Edel Rafael Rodea-Montero, Magali Yuyitzi Linarte-Guerra, Ricardo Garcia-Mora, Paulina Millán-Ramos, Sergio Manuel Orozco-Ramírez

“…In addition, we sought to develop a risk index on the basis of multivariable analysis allowing stratification of the probability of supplemental oxygen requirement upon discharge from the PACU. <b>Materials and Methods</b>: In this cross-sectional, retrospective, observational study, the pre- and intra-anesthetic characteristics of adult patients who underwent spinal surgery at any vertebral level under balanced general anesthesia in a tertiary hospital were retrieved. …”
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Soluble DLL1 as an Indicator of acute kidney injury and postoperative delirium following cardiac surgery: a secondary analysis of a prospective study by Thomas Simon Zajonz, Fabian Edinger, Melanie Markmann, Anna-Lena Schreiner, Frauke Beckert, Markus A. Weigand, Florian Uhle, Bernd Niemann, Michael Sander, Christian Koch, Emmanuel Schneck

“…This study aims to investigate sDLL1 levels, examining its potential relationship with AKI and postoperative delirium (POD) after cardiac surgery and its predictive value. Methods This secondary analysis of a prospective observational trial included elective cardiac surgery patients. …”
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Using Machine Learning to Predict Outcomes Following Thoracic and Complex Endovascular Aortic Aneurysm Repair by Ben Li, Naomi Eisenberg, Derek Beaton, Douglas S. Lee, Badr Aljabri, Leen Al‐Omran, Duminda N. Wijeysundera, Ori D. Rotstein, Thomas F. Lindsay, Charles de Mestral, Muhammad Mamdani, Graham Roche‐Nagle, Mohammed Al‐Omran

“…We developed machine learning algorithms to predict outcomes following TEVAR and complex EVAR. Methods The Vascular Quality Initiative database was used to identify patients who underwent elective TEVAR and complex EVAR for noninfrarenal aortic aneurysms between 2012 and 2023. …”
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Planetary health education in undergraduate medical education in Germany: results from structured interviews and an online survey within the national PlanetMedEd Project by Fabio Grieco, Sandra Parisi, Anne Simmenroth, Michael Eichinger, Michael Eichinger, Janina Zirkel, Janina Zirkel, Sarah König, Jana Jünger, Jana Jünger, Eva Geck, Eva-Maria Schwienhorst-Stich

“…This study therefore aimed (a) to assess the current implementation of Planetary Health in undergraduate medical education in Germany and (b) to explore its characteristics as a foundation to develop evidence-informed recommendations for mainstreaming Planetary Health Education in medical schools in Germany.MethodsThe study comprised structured interviews followed by an online survey, both targeting all 39 medical schools in Germany. …”
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