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Current and Near-Future Technologies to Quantify Nanoparticle Therapeutic Loading Efficiency and Surface Coating Efficiency with Targeted Moieties
Published 2025-03-01“…Accurate quality control methods for nanoparticle therapeutic payload and coating characterization are critical for attaining the desired levels of batch repeatability, drug/gene loading efficiency, targeting molecule coating effectiveness, and safety profiles. …”
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Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions.
Published 2020-07-01“…In addition, we also discovered that gene conversion was less efficient when the DSB could be repaired using a homologous template, suggesting that the trinucleotide repeat may interfere with gene conversion too. …”
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Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross-stage recognition of glutamate-rich repeats
Published 2025-01-01“…It is well established that antibodies can efficiently block parasite transmission. In search for naturally acquired antibodies targets on sexual stages, we established an efficient method for target-agnostic single B cell activation followed by high-throughput selection of human monoclonal antibodies (mAbs) reactive to sexual stages of Pf in the form of gametes and gametocyte extracts. …”
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De novo identification of satellite DNAs in the sequenced genomes of Drosophila virilis and D. americana using the RepeatExplorer and TAREAN pipelines.
Published 2019-01-01“…Our results indicate that raw sequencing reads can be efficiently used to detect satDNAs, but that abundant tandem repeats present in dispersed arrays or associated with transposable elements are frequent false positives. …”
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Effect of Layer Spacing on Fracture Development and Seepage Evolution of Surrounding Rocks During Repeated Mining Under Insufficiently Collapsed Gob
Published 2025-06-01“…Our findings provide critical insights for ensuring the safety and improving the efficiency of repeated mining under insufficiently collapsed gobs.…”
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The effectiveness of the implementation of new technologies in the prevention of purulent complications of repeated surgеries for complications of fractures of the proximal femur o...
Published 2016-06-01“…According to the literature repeated surgery increases the risk of postoperative purulent complications in several times. …”
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Novel human single-domain antibodies exert potent anti-tumor activity by targeting EGF-like repeat epitope of EpCAM
Published 2025-02-01“…Single-domain antibodies (sdAbs), in contrast, offer advantages such as efficient tumor penetration and reduced immunogenicity. …”
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Aberrant placental structure is corrected with repeated nanoparticle-mediated IGF1 treatments in a Guinea pig model of fetal growth restriction
Published 2025-09-01“…We have previously shown efficacy of repeated placental nanoparticle-mediated insulin-like 1 growth factor (IGF1) treatment in improving placental efficiency (increased fetal-placental weight ratio) and correcting fetal growth in a maternal nutrient restriction (MNR) guinea pig model of FGR. …”
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Self-Healing and Mechanical Behaviour of Fibre-Reinforced Ultra-High-Performance Concrete Incorporating Superabsorbent Polymer Under Repeated and Sustained Loadings
Published 2024-11-01“…In addition, the mechanical performance of ambient-, water-, and 100% RH-cured prismatic specimens (100 mm × 100 mm × 500 mm) under repeated load was studied under the same curing conditions. …”
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THE EFFICIENCY AND SAFETY OF SECONDARY PREVENTION OF ISCHEMIC STROKE
Published 2014-07-01“…Prior IS is related to the drastically increased risk of repeat IS. Antiplatelet therapy is an efficient way to prevent repeat IS. …”
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The Examination of SQL Queries Efficiency in Chosen IT System
Published 2023-09-01Get full text
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Efficiency of lachrymal sac drainage in newborns with dacryocystocele
Published 2016-12-01Get full text
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Efficiency of assisted hatching of the cryopreserved–melted embryos
Published 2018-04-01“…To measure outcomes of clinical research of efficiency of assisted hatching of cryopreserved embryos. …”
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Efficiency of Noninvasive Ventilation in Acute Heart Failure
Published 2008-06-01“…Objective: to evaluate the efficiency of noninvasive supporting ventilation in patients with acute cardiorespiratory failure in the early postoperative period after cardiac surgery under extracorporeal circulation. …”
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