Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan by Kaori Mukai, Robert Cost, Xin Sheen Zhang, Emily Condiff, Joanne Cotton, Xiaohua Liu, Ekaterina Boudanova, Björn Niebel, Peter Piepenhagen, Xinming Cai, Anna Park, Qun Zhou

“…Thus, the antibody-M6P conjugate is highly efficient in inducing internalization and subsequent lysosome-mediated protein degradation. …”
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Carbon-Supported Fe-Based Catalyst for Thermal-Catalytic CO₂ Hydrogenation into C₂₊ Alcohols: The Effect of Carbon Support Porosity on Catalytic Performance by Yongjie Chen, Lei Jiang, Simin Lin, Pei Dong, Xiaoli Fu, Yang Wang, Qiang Liu, Mingbo Wu

“…We wish our work could enrich the horizon for the rational design of highly efficient carbon-supported Fe-based catalysts.…”
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Development and mechanistic investigation of recombinant type III humanized collagen gel for mid-facial soft tissue repair by Qian Wang, Qifei An, Yuanzhou Wang, Jingbo Yang, Xiujuan Zhang, Shibo Jiang, Min Chen, Lu Lu, Yun Zhu

“…Therefore, we herein report the development of a novel recombinant humanized type III collagen gel (C3Gel) through rational design and modification of a commercially available recombinant type III humanized collagen lyophilized fiber product. …”
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Natural Enzyme‐Loaded Polymeric Stealth Coating‐Armed Engineered Probiotics by Disrupting Tumor Lactate Homeostasis to Synergistic Metabolism‐Immuno‐Enzyme Dynamic Therapy by Liuzhou Mao, Bahriman Xarpidin, Rui Shi, Yuting Lin, Haohua Hu, Caisheng Wu, Zheng Luo, Yun‐Long Wu

“…However, developing bacterial‐based lactate regulation platforms is still facing great challenges due to bacterial modification impacts on activity, macrophage phagocytosis, and complex tumor microenvironment. …”
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A holistic rat model to investigate therapeutic interventions in Parkinson’s disease: viral induction of a slow-progressing motor phenotype, dopaminergic degeneration and early mic... by Ekaterini Kefalakes, Franziska J. Mewes, Diana Peristich, Clara Plötner, Volodymyr Shcherbatyy, Julia Schipke, Friederike Schneider, Christopher Käufer, Regina Rumpel

“…Taken together, we established an early AAV/DJ-mediated model for Parkinson’s disease in rats, which not only shows histological hallmarks but due to its progressive motor phenotype also provides a therapeutic window suitable for future pharmacological modification.…”
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Experimental study on the long-term conductivity of self-support fracture in deep shale reservoirs by Yu Sang, Yintong Guo, Haoyong Huang, Debin Xia, Liqing Chen, Zhen Zhang, Junchuan Gui

“…Abstract Reservoir modification fracturing technology is one of the key technologies for the effective development of deep shale gas reservoirs. …”
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Spin Manipulation of Co sites in Co9S8/Nb2CTx Mott–Schottky Heterojunction for Boosting the Electrocatalytic Nitrogen Reduction Reaction by Shuai Zhang, Weihua Zhao, Jiameng Liu, Zheng Tao, Yinpeng Zhang, Shuangrun Zhao, Zhihong Zhang, Miao Du

“…This work demonstrates a promising strategy for constructing heterojunction electrocatalysts for efficient eNRR.…”
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Dynamic mechanical performance of a pre-compressed high damping rubber-based elastomer for vibration damping systems by Jia-Xuan He, Zhao-Dong Xu, Zhong-Wei Hu, Teng Ge, Qiang-Qiang Li, Yao-Rong Dong, Gabriele Milani

“…The elastomer is based on carboxylated nitrile-butadiene rubber (XNBR) as the matrix and is modified through nanofiller reinforcement and sacrificial bonds. This modification effectively overcomes the conventional conflict between damping efficient and mechanical strength. …”
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Construction and high-throughput screening of gradient nanowire coatings on titanium surface towards ameliorated osseointegration by Ruiyue Hang, Yuyu Zhao, Huanming Chen, Xiaomei Li, Runhua Yao, Yonghua Sun, Xiaohong Yao, Long Bai, Huaiyu Wang, Yong Han, Ruiqiang Hang

“…Surface nano-modification has emerged as an effective strategy to enhance osseointegration of titanium (Ti) implants. …”
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MXenes in biosensing: Enhancing sensitivity and flexibility – A review of properties, applications, and future directions by Ali Mohammad Amani, Lobat Tayebi, Ehsan Vafa, Alireza Jahanbin, Milad Abbasi, Ahmad Vaez, Hesam Kamyab, Lalitha Gnanasekaran, Shreeshivadasan Chelliapan

“…It also discusses the obstacles and limitations that must be overcome to fully realize MXenes' potential in biosensor technology, such as issues with large-scale manufacturing, surface modification, and long-term stability. The review concludes by discussing future directions and advancements in this field.…”
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Enhanced Anti‐Tumour Efficacy of iRGD‐Modified Cell‐Bound Membrane Vesicles (iRGD‐CBMVs) as a Novel Drug Carrier by Haonan Zhao, Zhendong Huang, Qinghua Sheng, Wenxiang Shao, Min Zeng, Kun Wang, Yang Zhang, Ying Qin, Zhihao Xiong, Lizhen Chen, Huaying Wang, Tong Rong, Zhitao Qiu, Hongda Zhuang, Zhiwen Wu, Yuan Zhang, Wendiao Zhang, Yong Chen

“…Laser confocal microscopy and 1H Nuclear Magnetic Resonance Spectra (1H NMR) have confirmed the CBMVs' iRGD modification and effective encapsulation with DOX (iRGD‐CBMVs‐DOX). …”
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Hot isostatic pressing elimination of process-induced defects in laser powder bed fusion fabricated DZ125 superalloy: Microstructure evolution and mechanical property enhancement by Hairui Gao, Zhenwu Zhang, Jikang Li, Jiangtao Sun, Honghao Xiang, Boyang Wu, Wei Li, Chao Cai, Qingsong Wei

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Research on Corrosion Protection of TETA-Modified Li–Al LDHs for AZ31 Magnesium Alloy in Simulated Seawater by Sifan Tu, Liyan Wang, Sixu Wang, Haoran Chen, Qian Huang, Ning Hou, Zhiyuan Feng, Guozhe Meng

“…To enhance corrosion resistance, this work combines Li–Al layered double hydroxides (LDHs) with triethylenetetramine (TETA) inhibitors to form an efficient corrosion protection system. Electrochemical tests, SEM, FT-IR, XPS, and 3D depth-of-field microscopy were employed to evaluate TETA-modified Li–Al LDH coatings at varying concentrations. …”
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Electrolyte engineering and interphase chemistry toward high-performance nickel-rich cathodes: Progress and perspectives by Shangjuan Yang, Ke Yang, Jinshuo Mi, Shaoke Guo, Xufei An, Hai Su, Yanbing He

“…For this, various structural and interphase regulation strategies (such as coating modification, element doping, and electrolyte engineering) are developed to enhance the cycling survivability of Ni-rich cathodes. …”
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Power Production and Degradation of Pesticide Wastewater Through Microbial Fuel Cells with the Modified Activated Carbon Air Cathode by Hollow-Carbon and Carbon-Encapsulated Struct... by Xueli Zhang, Linhui Jia, Yu Liu, Ziqi Wang, Jumiao Qin, Qiuhong Wang, Xiao Zhao, Ming Zhong, Jianfeng Lang, Guangri Xu, Yanbing Wu, Chengxing Cui

“…This study offers new ideas in constructing composite confined structures and the as-designed Fe-Fe₃O₄-NC is a promising modification candidate for the commercial adoption of AC air cathodes.…”
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Liver-Targeting Nanoparticles GA-MSe@AR Treat NAFLD Through Dual Lipid-Lowering and Antioxidant Efficacy by Lei S, Wu Q, Zhang B, Lu M, Xia Y, Li N

“…GA-MSe@AR exhibited low toxicity, efficient cellular uptake, remarkable lysosomal escape ability, and high AR release efficiency in vitro. …”
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Chemical circularization of in vitro transcribed RNA for exploring circular mRNA design by Malgorzata Wasinska-Kalwa, Adam Mamot, Karol Czubak, Katarzyna Frankowska, Adam Ado Rajkiewicz, Tomasz Spiewla, Marcin Warminski, Zofia Pilch, Marta Szulc-Gasiorowska, Kacper Siekan, Andrzej Dziembowski, Dominika Nowis, Jakub Golab, Joanna Kowalska, Jacek Jemielity

“…Here, we report a method for chemically circularized in vitro transcribed RNAs of various lengths (chem-circRNAs; 35–4000 nt) with circularization efficiencies reaching up to 60%. This approach leverages a 5′ ethylenediamine modification and a periodate-oxidized 3′ end to drive intramolecular reductive amination. …”
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Chemoselective dual functionalization of proteins via 1,6-addition of thiols to trifunctional N-alkylpyridinium by Lujuan Xu, Maria J. S. A. Silva, Jaime A. S. Coelho, Joscha Borho, Nicole Stadler, Holger Barth, Seah Ling Kuan, Tanja Weil

“…Here, we introduce N-alkylpyridinium reagents as soft electrophiles for chemoselective dual modification of cysteine residues in peptides or proteins via a 1,6-addition reaction. …”
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Magnetically Modified Bentonite for Optimized Erythromycin Removal via RSM and DFT Analysis by Ying-Chieh Hung, Yu-Qi Wu, Ru-Hau Ye, Hsiu-Min Hung, Gui-Bing Hong

“…This study presents a novel adsorbent synthesized by magnetically modifying calcined natural bentonite with Fe₃O₄ nanoparticles to enhance ERY removal. The modification increased the surface area, with the highest adsorption observed at pH 11. …”
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Targeting drug cocktail hydrogel platform for inhibiting tumor growth and metastasis by Liying Xiao, Jianwen Hou, Hongxiang Liu, Qiang Lu

“…Both the targeting modification of SNR and the optimized co-delivery of DOX and PTX improved the therapeutic efficiency in vitro and in vivo. …”
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