Two-dimensional cell membrane chromatography guided screening of myocardial protective compounds from Yindan Xinnaotong soft capsule by Si-Min Shao, Xuan Ji, Xing Wang, Run-Zhou Liu, Yu-Ru Cai, Xiaobing Lin, Ze-Jie Zeng, Ling Chen, Liu Yang, Hua Yang, Wen Gao

“…Methods An imidazole-modified silica gel exhibiting high modification efficiency and protein binding capacity was synthesized to enhance the longevity and efficiency of H9c2/CMC. …”
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Caffeic acid and chlorogenic acid mediate the ADPN-AMPK-PPARα pathway to improve fatty liver and production performance in laying hens by Wenjie Tian, Gerard Bryan Gonzales, Hao Wang, Youyou Yang, Chaohua Tang, Qingyu Zhao, Junmin Zhang, Huiyan Zhang, Yuchang Qin

“…These findings provide a foundation for CA and CGA as therapeutic agents for fatty liver disease and related metabolic diseases in hens, and also offer insights into the targeted modification of CGA (including the isomer of CGA) into CA, thereby providing novel strategies for the efficient utilization of CGA. …”
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The Effect of Reducing Vibration Of Lathe to Aisi 4340 Surface Roughness by Gilang Awan Yudhistira, Muhamad Fitri, Adlan Mizan, Muhammad Miftah Rafi, Hasan Anugrah

“…Modification on changed the entry angle has better surface roughness which the value of 1.3 µm.…”
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Enhancing combustion and emission characteristics of CI engines through atomization and fuel–air mixing using non-circular orifices: A path towards sustainable biodiesel utilizatio... by Mukesh Yadav, Ashok Kumar Yadav, Aqueel Ahmad

“…Furthermore, the simultaneous implementation of non-circular orifices and fuel modification techniques exhibited the potential for enhancing thermal efficiency and decreasing emissions in CI engines.…”
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Advanced solar radiation prediction using combined satellite imagery and tabular data processing by Mohammed Attya, O. M. Abo-Seida, H. M. Abdulkader, Amgad M. Mohammed

“…The framework divides into two paths; the first path take the input as the satellite images; this stages contains three steps; the first step is removing noise using latent diffusion model, the second step is about pixel imputation using a modified RF + Identity GAN (this model contains two modification the first modification is adding the identity block to solve mode collapse problem in the GANs and the second modification is to add the 8-connected pixel to generate a value of missing pixel near to the real missed pixel. …”
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Recent advances of thin film composite nanofiltration membranes for Mg2+/Li+ separation by Hao Yi Peng, Siew Kei Lau, Wai Fen Yong

“…Additionally, different NF membranes were categorized based on the modification to the interfacial polymerization, such as types of aqueous monomer, addition of nanofillers in aqueous phase, addition of nanofillers in substrate, addition of an extra layer within the membrane, and other modifications. …”
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Impact of shape and global β on ASDEX Upgrade pedestal structure by L. Radovanovic, E. Wolfrum, M.G. Dunne, G.F. Harrer, F. Aumayr, the ASDEX Upgrade Team

“…The stability and confinement of the pedestal, the outermost region of the confined plasma in a tokamak, are crucial for its efficient operation and performance. This work describes ASDEX Upgrade experiments designed to analyse the pedestal structure under varying conditions of normalized poloidal pressure ( β _pol ) and plasma shaping. …”
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Ub-POD: A Ubiquitin-Specific Proximity-Dependent Labeling Technique to Identify E3 Ubiquitin Ligase Substrates in Human Cells by Urbi Mukhopadhyay, Sophie Levantovsky, Christian Behrends, Sagar Bhogaraju

“…Ubiquitination is a post-translational protein modification that regulates a vast majority of processes during protein homeostasis. …”
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Engineered Exosomes as Smart Drug Carriers: Overcoming Biological Barriers in CNS and Cancer Therapy by Tanvi Premchandani, Amol Tatode, Jayshree Taksande, Milind Umekar, Mohammad Qutub, Ujban Md Hussain, Priyanka Singanwad

“…For CNS delivery, exosomes functionalized with brain-homing peptides (e.g., RVG or TfR ligands) have enabled the efficient transport of neuroprotective agents or gene-editing tools to treat Alzheimer’s disease or glioblastoma. …”
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Deep-Learning-Based Segmentation of Cells and Analysis (DL-SCAN) by Alok Bhattarai, Jan Meyer, Laura Petersilie, Syed I. Shah, Louis A. Neu, Christine R. Rose, Ghanim Ullah

“…The results from DL-SCAN are consistent, reproducible, and free from user bias, allowing efficient and rapid analysis of experimental data in an objective manner. …”
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Multi-objective optimization of a novel control algorithm and scheduling procedure for optimal use of energy storage systems by Amirhossein Hamzeiyan, Armin Ebrahimi

“…This modification requires minimal changes to the existing algorithm. …”
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Automated Road Extraction from Satellite Imagery Integrating Dense Depthwise Dilated Separable Spatial Pyramid Pooling with DeepLabV3+ by Arpan Mahara, Md Rezaul Karim Khan, Liangdong Deng, Naphtali Rishe, Wenjia Wang, Seyed Masoud Sadjadi

“…Convolutional neural networks (CNNs), especially the DeepLab series known for its proficiency in semantic segmentation due to its efficiency in interpreting multi-scale objects’ features, address some of these challenges caused by the varying nature of roads. …”
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NanoAbLLaMA: construction of nanobody libraries with protein large language models by Xin Wang, Haotian Chen, Bo Chen, Lixin Liang, Fengcheng Mei, Bingding Huang

“…This study introduces a novel approach leveraging protein large language models (LLMs) to generate germline-specific nanobody sequences, enabling efficient library construction through statistical analysis.MethodsWe developed NanoAbLLaMA, a protein LLM based on LLaMA2, fine-tuned using low-rank adaptation (LoRA) on 120,000 curated nanobody sequences. …”
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Applications of cell penetrating peptide-based drug delivery system in immunotherapy by Jing-Jing Du, Ru-Yan Zhang, Shangchi Jiang, Shanshan Xiao, Yiting Liu, Yongheng Niu, Wen-Xiang Zhao, Dongyuan Wang, Dongyuan Wang, XianShi Ma

“…Besides, inappropriate chemical modification can lead to membrane disruption and nonspecific toxicity. …”
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High Sensitivity and Selectivity of PEDOT/Carbon Sphere Composites for Pb²⁺ Detection by Lirong Ma, Zhuangzhuang Wang, Xiong Liu, Feng Xu, Tursun Abdiryim

“…As a result, it is critical to create an efficient approach for identifying heavy metal ions. …”
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Synergizing sono-piezo with exosome suppression using doping-engineered hydroxyapatite for potentiated tumor treatment through immunoactivation by Xinran Qu, Qin Fan, Yingying Liu, Jinqiao Zhang, Boyu Yuan, Xianzhou Cai, Luli Ji, Rulin Zhuang, Ziliang Dong

“…However, their potential is limited by poor piezoresponse, low catalytic efficiency, and the exacerbation of immunosuppression due to ROS-induced release of tumor-derived exosomes. …”
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Microbiota and Cytokine Modulation: Innovations in Enhancing Anticancer Immunity and Personalized Cancer Therapies by Hamidreza Farhadi Rad, Hamed Tahmasebi, Samaneh Javani, Maral Hemati, Darya Zakerhamidi, Masoomeh Hosseini, Farnaz Alibabaei, Seyedeh Zahra Banihashemian, Valentyn Oksenych, Majid Eslami

“…This complex interaction provides an opportunity for novel cancer therapies by highlighting the possibility of microbiome modification as a therapeutic approach in personalized oncology approaches.…”
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Spot Urine PCR as an Independent Predictor of Renal Disease in Patients with Essential Hypertension by Spoorthi P. Yadagudde, Jayannan Jayasenan, Anbarasu Duraisamy

“…Spot urine PCR proved to be an effective and cost-efficient tool for early detection of kidney impairment in hypertensive patients. …”
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Response Analysis of an Experimental Study on the Effect of Speed and Premixed Fuel Ratio on Performance and Emissions in RCCI Engine by Habtamu Deresso Disassa, Venkata Ramayya Ancha, Ramesh Babu Nallamothu, Bisrat Yoseph, Getachew Alemayehu

“…Even though CI engines are more efficient than SI engines due to their ability to operate at a greater compression ratio, a leaner charge, and lower throttle losses, they have higher PM and nitrogen oxide emissions. …”
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Estimation of Magnet Temperature Using Disturbance Observers of Permanent Magnet Synchronous Motor for Driving Single Rotary Compressor Without Lookup Table by Seoyun Lee, Jeonghyeok Kim, Hojun Kim, Dongho Kim, Jinyoung Choi, Hyun-Sam Jung

“…The growing global demand for household air conditioners necessitates reliable and efficient motor operation under high-temperature conditions. …”
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