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  1. 901
  2. 902

    Development of a Cationic Polymeric Micellar Structure with Endosomal Escape Capability Enables Enhanced Intramuscular Transfection of mRNA-LNPs by Siyuan Deng, Han Shao, Hongtao Shang, Lingjin Pang, Xiaomeng Chen, Jingyi Cao, Yi Wang, Zhao Zhao

    Published 2024-12-01
    “…<b>Background/Objectives:</b> The endosomal escape of lipid nanoparticles (LNPs) is crucial for efficient mRNA-based therapeutics. Here, we present a cationic polymeric micelle (cPM) as a safe and potent co-delivery system with enhanced endosomal escape capabilities. …”
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    <i>Caulobacter</i> Strains Code for Novel Restriction Endonucleases That Protect Them from Bacteriophage Infections by Ian Sisto, Bert Ely

    Published 2025-02-01
    “…Bacteriophages grown on <i>Caulobacter vibrioides</i> strain CB15 have reduced plating efficiency on other <i>Caulobacter</i> strains. To determine the cause of this reduced plating efficiency, we performed a series of experiments that demonstrated that the reduced plating efficiency is due to a novel set of restriction and modification (RM) enzymes that are present in most of the <i>Caulobacter</i> strains that we tested. …”
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  5. 905

    EdgeGuard: Decentralized Medical Resource Orchestration via Blockchain-Secured Federated Learning in IoMT Networks by Sakshi Patni, Joohyung Lee

    Published 2024-12-01
    “…The development of medical data and resources has become essential for enhancing patient outcomes and operational efficiency in an age when digital innovation in healthcare is becoming more important. …”
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  6. 906

    Sorption of strontium on the composite sorbent based on cellulose and hydrated antimony pentoxide by V. V. Galysh, M. T. Kartel, W. Janusz, E. Skwarek, A. A. Nikolaichuk

    Published 2017-11-01
    “…Hydrated antimony pentoxide characterized by amorphous structure and modification process does not affect cellulose crystallinity. …”
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    Liposomal Encapsulation of Carob (<i>Ceratonia siliqua</i> L.) Pulp Extract: Design, Characterization, and Controlled Release Assessment by Aleksandra A. Jovanović, Dragana Dekanski, Milena D. Milošević, Ninoslav Mitić, Aleksandar Rašković, Nikola Martić, Andrea Pirković

    Published 2025-06-01
    “…<b>Results:</b> The findings revealed a high encapsulation efficiency across all samples (>70%). The particle size and PDI measurements confirmed the presence of a multilamellar and uniform liposomal system before post-processing modifications. …”
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    Comparative analysis of selective gas adsorption on metal-organic frameworks: Cu–(abtc) vs. Cu–(hbtc) by Prudhviraj Medikonda

    Published 2025-01-01
    “…The functional group was modified by replacing the double bond (N = N) in a MOF derived from abtc with an NH–NH group (named hbtc). This modification highlights the enhanced affinity of the NH–NH group compared to N = N. …”
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  13. 913

    The Effect of Cone Area Variations on the Continuous Discharges Flow (CDF) Method Sedimentation Unit as a New Method for Raw Water Turbidity Removal by Ridwan Ridwan, Reri Afrianita, Aulia Massyaf Putri, Reski Anggika

    Published 2023-07-01
    “…The Sedimentation Unit Continuous Discharges Flow (CDF) method is a modification by adding a continuous and controlled discharge flow as a net force acting on the particles to increase the efficiency of turbidity removal by applying the principle of a leaky tank at the bottom of the settling zone. …”
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  14. 914

    Distinct infectivity and neutralization antibody responses in the highly homologous AAV Go.1 and AAV5 by Mei Li, Haixiao Ma, Yang Wu, Yunling Gao, Jie Wang, Jie Wang, Hanbing Wang

    Published 2025-04-01
    “…To further enhance transduction efficiency, we introduced site-specific mutations in the VP1 unique (VP1u) region and VP1/2 common region.ResultsThe rep gene modification led to a significantly higher packaging efficiency for rAAV Go.1 compared to the original goat AAV. rAAV Go.1 exhibited markedly higher transduction efficiency than AAV5 in both in vitro and in vivo models. …”
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    Hierarchical predictive optimal control for range extension of EV with ANN based torque control for IPMSM drives by Lekshmi S, Lal Priya P S

    Published 2024-12-01
    “…These advancements are realised without substantial modifications to the EV’s drivetrain, representing a significant step forward in sustainable and efficient electric mobility.…”
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  17. 917

    Accelerated Bayesian optimization for CNN+LSTM learning rate tuning via precomputed Gaussian process subspaces in soil analysis by Xiaolong Chen, Hongfeng Zhang, Cora Un In Wong, Zhengchun Song

    Published 2025-08-01
    “…This work bridges the gap between computational efficiency and probabilistic robustness, with broader implications for automated machine learning in geoscientific applications.MethodThe key innovation lies in a subspace-accelerated GP surrogate model that precomputes low-rank approximations of covariance matrices offline, thereby decoupling the costly hyperparameter tuning from the online acquisition function evaluations. …”
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  18. 918

    Bayesian Inference for Zero-Modified Power Series Regression Models by Katiane S. Conceição, Marinho G. Andrade, Victor Hugo Lachos, Nalini Ravishanker

    Published 2024-12-01
    “…Additionally, we introduce a measure of Bayesian efficiency to evaluate the impact of prior information on parameter estimation. …”
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  19. 919

    Proposing a modified system based on recovery of preset pressurization energy in the integrated pumped-hydro and compressed gas energy storage system by Amin Hadidi

    Published 2025-09-01
    “…For this purpose, the energy spent to create pressure inside the system's high-pressure container is recovered in the discharge stage. This modification prevents energy losses in the storage system and consequently, enhances its efficiency, considerably. …”
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