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  1. 2641

    Nanosensitizer-assisted sonodynamic therapy for breast cancer by Jing Yu, Jun-Rui Hu, Yi Tian, Yu-Meng Lei, Hai-Man Hu, Bing-Song Lei, Ge Zhang, Yao Sun, Hua-Rong Ye

    Published 2025-04-01
    “…However, the clinical translation of SDT faces challenges, including the limited efficiency of sonosensitizers and resistance posed by the tumor microenvironment. …”
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    Article
  2. 2642

    Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader by Li Chen, Yahui Zou, Renhong Sun, Mei Huang, Xiaotong Zhu, Xiao Tang, Xiaobao Yang, Dake Li, Gaofeng Fan, Yu Wang

    Published 2024-12-01
    “…By integrating protein degradation technology, we synthesized a PROTAC molecule 180055 based on the Rucaparib junction and VHL ligand, which efficiently and selectively degraded PARP1 and inhibited PARP1 enzyme activity without a noticeable DNA trapping effect. …”
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    Article
  3. 2643

    A study of the applicability of a straw-fired batch boiler as a heat source for a small-scale cogeneration unit by Sornek Krzysztof, Filipowicz Mariusz

    Published 2016-12-01
    “…This is possible provided that an automatic fuel supply system is applied. Assuming that the efficiency of the electricity generation system is not less than 10%, it will be possible to generate 2-3 kW of electricity. …”
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    Article
  4. 2644

    Synthesis of New DltA Inhibitors and Their Application as Adjuvant Antibiotics to Re-Sensitize Methicillin-Resistant <i>Staphylococcus aureus</i> by David Leparfait, Alexandre Mahé, Xiao Feng, Delphine Coupri, Fabien Le Cavelier, Nicolas Verneuil, Emmanuel Pfund, Aurélie Budin-Verneuil, Thierry Lequeux

    Published 2025-06-01
    “…The synthesis of a new acyclic and cyclic series of D-Ala-AMP analogues was reported. Chemical modifications were introduced on the carbohydrate, the sulfamate linker, and/or the amino-acid <i>N</i>-terminal moiety in order to increase <i>in vivo</i> stability and cell permeability. …”
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    Article
  5. 2645

    Features of the Use of Personal Protective Equipment in the Foci of a New Coronavirus Infection by A. A. Kuzin, A. P. Yumanov, A. A. Degtyarev, G. G. Eremin

    Published 2021-01-01
    “…As a result of using a whole range of disposable PPE of various modifications, the features and disadvantages of their operation in the field were established. …”
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    Article
  6. 2646

    Commissioning a clinical proton pencil beam scanning beamline for pre-clinical ultra-high dose rate irradiations on a cyclotron-based system by Jatinder Saini, Jatinder Saini, Danielle P. Johnson Erickson, François Vander Stappen, Matt Ruth, Matt Ruth, Sunan Cui, Sunan Cui, Vanessa Gorman, Séverine Rossomme, Ning Cao, Ning Cao, Eric C. Ford, Eric C. Ford, Juergen Meyer, Juergen Meyer, Charles Bloch, Charles Bloch, Tony Wong, Tony Wong, Clemens Grassberger, Ramesh Rengan, Ramesh Rengan, Jing Zeng, Jing Zeng, Marco Schwarz, Marco Schwarz

    Published 2024-11-01
    “…BackgroundThis manuscript describes modifications to a pencil beam scanning (PBS) proton gantry that enables ultra-high dose rates (UHDR) irradiation, including treatment planning and validation.MethodsBeamline modifications consisted of opening the energy slits and setting the degrader to pass-through mode to maximize the dose rate. …”
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    Article
  7. 2647

    PRINCIPLES OF RE-ENGINEERING METHODOLOGY FOR TECHNOLOGICAL PROCESS IN PROCESSING OF RAW MATERIAL COMPONENTS WHILE PRODUCING CEMENT AND SILICATE PRODUCTS by I. A. Busel, P. I. Busel

    Published 2014-10-01
    “…Grinding process is characterized by high energy consumption and low productivity. Nowadays efficiency of the ball mills applied for grinding is rather low. …”
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    Article
  8. 2648

    ABA-induced alternative splicing drives transcriptomic reprogramming for drought tolerance in barley by Anna Collin, Hubert Matkowski, Ewa Sybilska, Asmarany Biantari, Oliwia Król, Agata Daszkowska-Golec

    Published 2025-04-01
    “…Transcriptomic analysis revealed that ABA pre-treatment primed plants for faster activation of stress-responsive pathways, with enhanced expression of genes related to chromatin modifications, RNA metabolism, and ABA signaling during drought. …”
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    Article
  9. 2649

    Cyanobacteria: Photosynthetic cell factories for biofuel production by Bharat Kumar Majhi

    Published 2025-05-01
    “…Furthermore, they have higher photosynthetic efficiency, especially in CO2-rich environments, making them more desirable. …”
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    Article
  10. 2650

    Tactics of Two-Stage IOL Implantation in Difficult Refractive Cases by A. A. Kasyanov

    Published 2021-10-01
    “…Our Sulcoflex IOL implantation experience has shown their high efficiency and safety.…”
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    Article
  11. 2651

    Experience of Using New Technologies in Retail Trade by A. A. Garnova

    Published 2024-10-01
    “…Apart from that opportunities were studied that can offer new technologies for improving operational efficiency of retail trade enterprises. A conclusion was made that they are used insufficiently. …”
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    Article
  12. 2652

    Review on heat transfer augmentation in helically coiled tube heat exchanger by Md Atiqur Rahman

    Published 2024-11-01
    “…Their impact on overall system efficiency and size is substantial. A comprehensive review addressing passive heat transfer enhancement methods in HTHXs is notably absent. …”
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    Article
  13. 2653

    TRENDS OF MODERNIZATION OF FOOD SERVICE INDUSTRY ENTERPRISES IN COUNTRYSIDE by Glebova S.Y., Golub O.V., Ribakova T.M.

    Published 2015-06-01
    “…The peculiarities of the format modifications of the enterprise, its reconstruction , cateringand assortment are shown. …”
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    Article
  14. 2654

    STUDY REGARDING USING SOLAR ENERGY FOR HOUSEHOLD`S SUFFICIENCY AND RURAL COMMUNITIES DEVELOPMENT IN UKRAINE by Inna LOZYNSKA, Olena SKRYPNYK, Denys SKRYPNYK

    Published 2021-01-01
    “…The recent statistical data and market studies have shown that today Ukraine electricity market requires certain changes and modifications. Reform is necessary to build a new model of interaction between all participants in the energy market. …”
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    Article
  15. 2655

    A hybrid Genetic Algorithm and Fuzzy Logic approach to ergonomic design of workstations in metal casting operations by Intan Berlianty, Irwan Soejanto, Indun Titisariwati, Favian Ersanta Andhika Putra, Wahyu Tri Utami, Mohamad Kamil Insani

    Published 2024-12-01
    “…Real-time adjustments, such as desk height modifications and improved ventilation, effectively enhanced worker safety and comfort. …”
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    Article
  16. 2656

    Using Burke's Dramatistic Pentad to Interpret Chinese "Gao-Kao" High Stakes Testing and Stressing - Paralelled Testing in the U.S. as Cross-Cultural Context by Jim Schnell, Xiaoting Huang, Lei Wang

    Published 2013-01-01
    “…In this study, we tried two modifications to the traditional test toconnect the assessment outcomes with school accountability. …”
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    Article
  17. 2657

    Enhancing Solar Thermal Energy Storage via Torsionally Modified TPMS Structures Embedded in Sodium Acetate Trihydrate by Martin Beer, Radim Rybár

    Published 2025-06-01
    “…This study focuses on the numerical analysis of the impact of geometric modifications of sheet-gyroid structures on heat transfer in thermal energy storage systems utilizing sodium acetate trihydrate as a phase change material. …”
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    Article
  18. 2658

    Development and Characterization of Nanoparticles for the Delivery of Gemcitabine Hydrochloride by Rekha Khaira, Jyoti Sharma, Vinay Saini

    Published 2014-01-01
    “…Percent entrapment efficiency of different formulations was around ∼54% to 65%. …”
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    Article
  19. 2659

    Computational Study Using Tight-Binding Propagation Method: Optical Properties of Defected WS2 Monolayer by I Wayan Windu Sara, I Gede Arjana

    Published 2025-05-01
    “…The presence of defects generally reduces optical performance in the visible range, potentially limiting solar cell efficiency. However, the defect-induced modifications in the infrared region suggest a new potential for WS₂ monolayers in infrared sensing applications. …”
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    Article
  20. 2660

    Dry Age Related Macular Degeneration – Oral Supplements, Which Combination and When ? by T. Lekha

    Published 2018-04-01
    “…Oxidative stress in the retina has been identified as an important predisposing factor which can be most efficiently modified by nutritional supplementation. …”
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