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Lactylation Modification as a Promoter of Bladder Cancer: Insights from Multi-Omics Analysis
Published 2024-11-01“…The establishment of a prognostic model for BLAC is of great significance for clinical prognosis prediction and treatment guidance. Lactylation modification is a newly discovered post-transcriptional modification of proteins, which is closely related to the occurrence and development of tumors. …”
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Modification of Canola Oil Properties Using Ethyl Oleate and <i>n</i>-Hexane
Published 2025-07-01“…Canola oil (rapeseed oil, RO), despite being a potential source of biofuel, needs some modifications of its properties to be effectively used as a fuel. …”
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223
Modular and efficient assembly of CRISPR vectors and construction of an apple gene editing efficiency evaluation system
Published 2025-08-01“…We aim to develop a modular and efficient CRISPR vector system, optimize the Agrobacterium-mediated transient delivery system in apple plantlets, and establish a corresponding evaluation system for assessing the efficiency of gene editing in apple. …”
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Structures and mechanisms of U6 snRNA m6A modification by METTL16
Published 2025-08-01“…Abstract The N 6-methyladenosine (m6A) modification in U6 snRNA, catalyzed by METTL16 using S-adenosylmethionine (SAM) as the methyl donor, is required for efficient and accurate pre-mRNA splicing. …”
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225
Electro-Conductive Modification of Polyvinylidene Fluoride Membrane for Electrified Wastewater Treatment: Optimization and Antifouling Performance
Published 2024-12-01“…This study provides a valuable reference for the efficient preparation of conductive membranes for cost-effective wastewater treatment.…”
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226
Effects of gear modifications in a North Atlantic pelagic longline fishery: A multiyear study.
Published 2023-01-01“…Conversely, the circle hooks were efficient in reducing the loggerhead sea turtle bycatch and were related to fewer catches of small sea turtle individuals. …”
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227
Physical Processing-Assisted pH Shifting for Food Protein Modification: A Comprehensive Review
Published 2025-07-01“…In that sense, this combined treatment approach provides a promising and eco-efficient protein modification strategy, and bridges technological innovation with sustainable resource utilization.…”
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228
Multi-strategy ugt mining, modification and glycosyl donor synthesis facilitate the production of triterpenoid saponins
Published 2025-05-01“…Therefore, the identification and modification of efficient, specific, and stable UGTs have attracted attention. …”
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229
Modification of essential factors mediating post-translational processing for high-quality protein expression in Penicillium
Published 2025-03-01“…The formation of mature proteins requires complex post-translational modification and processing. Efficient post-translational processing machinery is beneficial for the high-quality expression of proteins. …”
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230
Identifying and reporting modifications to surgical innovation: a systematic review of IDEAL/IDEAL-D studies
Published 2025-06-01“…This systematic review examined IDEAL studies to identify such modifications and establish recent practices around modification reporting to inform the development of future guidance to facilitate safe, transparent and efficient surgical innovation.Design Systematic review and thematic synthesis of studies reporting surgical innovation.Data sources Web of Science and Scopus were searched in July 2023 using citation tools to identify studies following the IDEAL framework (citing any of 13 key IDEAL/IDEAL framework publications and guideline papers).Eligibility criteria Primary research studies of any design that involved invasive innovative devices or procedures.Data extraction and synthesis Study characteristics and verbatim text for all reported modifications, including contextual information, were extracted. …”
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Influence of modification of the cast metal structure by solid phase particles on the nucleation of crystallization centers and their stability
Published 2022-12-01“…It is shown that if between the particle and the cladding layer the difference in chemical potentials of the contacting phases will exist throughout the entire process, and on the surface of the complex it will have a low value of surface tension, then such a particle will be stable, which takes place during adsorption of a surface-active component from a melt. Therefore, the efficiency of melt heterogenization and modification of the cast metal structure is determined by the thermodynamic activity of the substance of the transition layer to the material of the solid phase particle. …”
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233
MODIFICATION OF STRUCTURAL-PARAMETRICAL OPTIMIZATION ALGORITHM FOR CORRECTING DEVICES BASED ON MAGNITUDE-PHASE-DISTORTION LINKS
Published 2010-09-01“…Modification results of the quasioptimal structural-parametrical synthesis algorithm for control devices based on using the frequency-based quality parameters vector of the system are considered. …”
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234
Bioactive modification of microfluidic chip surface for detecting recombinant human bone morphogenetic protein-2
Published 2020-08-01“…It was found that the better capture efficiency of the first antibody could be obtained by using the higher power in the plasma treatment process. …”
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235
Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification
Published 2025-01-01“…We further explored here the role of the Q34 in the efficiency of codon decoding upon tobramycin exposure. …”
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236
RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification.
Published 2015-12-01“…We used tRNA-HydroSeq to document that little changes occurred in the relative levels of different tRNAs in maf1Δ cells. By contrast, the efficiency of N2,N2-dimethyl G26 (m(2)2G26) modification on certain tRNAs was decreased in response to maf1-deletion and associated with antisuppression, and was validated by other methods. …”
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237
Conversion of four-stroke engines to six-stroke engines using epicyclic gearing in camshaft modification
Published 2025-07-01“…This conversion employed the free-stroke Kelem model, one of the six-stroke engine approaches described in the literature, which required modifications only to the camshaft. Without modification to the original crankshaft gear, a fixed-ratio epicyclic gear was applied to the camshaft gear to achieve the necessary speed ratio between the crankshaft and camshaft. …”
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Reliable method for generating double-stranded DNA vectors containing site-specific base modifications
Published 2004-11-01Get full text
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