Harnessing the Power of Antimicrobial Peptides: From Mechanisms to Delivery Optimization for Topical Infections by Songhita Mukhopadhyay, Souha H. Youssef, Yunmei Song, Usha Y. Nayak, Sanjay Garg

“…Conventional AMP delivery systems, including polymeric, synthetic, and lipid-based nanoparticles and cubosomes, face challenges of microbial resistance mechanisms via efflux pump systems, bacterial cell membrane modifications, and protease enzyme release. This review explores strategies to optimize these delivery systems. …”
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Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies by Katie Facecchia, Lee-Anne Fochesato, Sidhartha D. Ray, Sidney J. Stohs, Siyaram Pandey

“…Metabolic pathways in mammalian cells utilize oxygen as the ultimate oxidizing agent to harvest free energy. They are very efficient, but not without risk of generating various oxygen radicals. …”
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Biomass as eco-friendly adsorbents for the removal of emerging pollutants from wastewater: A review by Asma Musfira Shabbirahmed, Anu Jacob, Pinaki Dey, Prathap Somu, Dibyajyoti Haldar

“…These bioadsorbents leverage functional groups like hydroxyl and carboxyl for efficient pollutant removal. The review highlights their adsorption capacities, optimal conditions, and challenges, such as leaching and interference from co-existing ions. …”
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Landscape of small nucleic acid therapeutics: moving from the bench to the clinic as next-generation medicines by Mohan Liu, Yusi Wang, Yibing Zhang, Die Hu, Lin Tang, Bailing Zhou, Li Yang

“…As a result of recent technological advances, efficient small nucleic acid delivery for therapeutic and biomedical applications has been achieved, accelerating their clinical translation. …”
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A TB40/E-derived human cytomegalovirus genome with an intact US-gene region and a self-excisable BAC cassette for immunological research by Kerstin Laib Sampaio, Anja Weyell, Narmadha Subramanian, Zeguang Wu, Christian Sinzger

“…The BAC cassette was inserted into the US2–US6 gene region (yielding TB40-BACKL7), relocated into the UL73/UL74 region with modifications that favor excision of the BAC cassette during replication in fibroblasts, and finally the US2–US6 region was restored, resulting in BAC clone TB40-BACKL7-SE When this BAC clone was transfected into fibroblasts at efficiencies >0.1%, replicating virus that had lost the BAC cassette appeared within 2 weeks after transfection, grew to high titers, and displayed the broad tropism of the parental virus. …”
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Subsea Nodule Recognition and Deployment Detection Method Based on Improved YOLOv8s by Jixin Li, Junchao Li, Bin Su, Yuxin Cui

“…This model is capable of real-time deployment on the Orange Pi 5 development board and is designed to efficiently and accurately identify seafloor polymetallic nodules. …”
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βTrCP facilitates MRN complex localization on chromatin to enhance DNA repair by Alejandro Belmonte-Fernández, Joaquín Herrero-Ruíz, Carmen Sáez, Miguel Á. Japón, Mar Mora-Santos, Francisco Romero

“…These signaling pathways are tightly controlled by various post-translational modifications, notably ubiquitination. Although several ubiquitin ligases have been implicated in different stages of the DNA damage response, our knowledge remains limited. …”
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Research Advances in CO_x Hydrogenation to Valuable Hydrocarbons over Carbon-Supported Fe-Based Catalysts by Shuai Peng, Chao Deng, Lujing Xu, Junli Li, Ruxing Gao

“…Among them, the development of efficient Fe-based catalysts has become a key issue. …”
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Biosynthesis of Ultrasonically Modified Ag-MgO Nanocomposite and Its Potential for Antimicrobial Activity by Wasiu B. Ayinde, Mugera W. Gitari, Munkombwe Muchindu, Amidou Samie

“…The efficiencies of the as-synthesized Ag-MgO nanocomposite against Escherichia coli were examined. …”
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Epithelial-mesenchymal transition in colorectal cancer metastasis and progression: molecular mechanisms and therapeutic strategies by Fangfang Nie, Xue Sun, Jizhuo Sun, Jingdong Zhang, Yuanhe Wang

“…This review systematically examines the molecular mechanisms regulating EMT in CRC, including key transcription factors; post-translational and epigenetic modifications; non-coding RNAs; and pivotal signaling pathways. …”
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Hydrogels as advanced drug delivery platforms for cancer immunotherapy: promising innovations and future outlook by Vahideh Mohammadzadeh, Hoda Atapour-Mashhad, Sedigheh Shahvali, Bahardokht Salehi, Mina Shaban, Maryam Shirzad, Afsaneh Salahvarzi, Marzieh Mohammadi

“…In addition, their structure and functional modifications in the development of stimuli-responsive hydrogels, injectable and multifunctional hydrogels are further discussed. …”
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Regulatory function of histidine kinase sensor encoding gene barA in bio-control effect of Rahnella aquatilis by Xiao Fenghu, Zhang Lei, Xie Zhen, Guo Yanbin, Chen Minwen, Wang Yongjun

“…The results also give us the indication that the modification of bacterial two-component regulation systems would be helpful to facilitate the application of biocontrol bacteria.…”
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Smart Poly(N-isopropylacrylamide)-Based Hydrogels: A Tour D’horizon of Biomedical Applications by Soumya Narayana, B. H. Jaswanth Gowda, Umme Hani, Mohammed Gulzar Ahmed, Zahrah Ali Asiri, Karthika Paul

“…Structurally, PNIPAM-based hydrogels (PNIPAM-HYDs) are chemically versatile, allowing for modifications that enhance biocompatibility and functional adaptability. …”
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Stable Multipoint Flux Approximation (MPFA) Saturation Solution for Two-Phase Flow on Non-K-Orthogonal Anisotropic Porous Media by Pijus Makauskas, Mayur Pal

“…This work provides a reliable and efficient tool for simulating coupled flow and transport processes, with applications in CO₂ storage, hydrogen storage, geothermal energy, and hydrocarbon recovery.…”
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Guidelines for implementing cleaner production strategies in a natural rubber gloves manufacturing industry by Muthukannan M, S. Saravanakumar, M.T. Sambandam, Umapathi K, R. Kamalakannan

“…The audit results for all different equipment are included in the report, along with suggested modifications and energy-saving achieved. The findings are still applicable as of the date and duration of the visit to the facility. …”
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The NSL complex regulates housekeeping genes in Drosophila. by Kin Chung Lam, Friederike Mühlpfordt, Juan M Vaquerizas, Sunil Jayaramaiah Raja, Herbert Holz, Nicholas M Luscombe, Thomas Manke, Asifa Akhtar

“…We find that an increased abundance of the histone modifications H4K16ac, H3K4me2, H3K4me3, and H3K9ac in gene promoter regions is characteristic of NSL-targeted genes. …”
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Zero Trust Strategies for Cyber-Physical Systems in 6G Networks by Abdulrahman K. Alnaim, Ahmed M. Alwakeel

“…The framework also achieves high scalability and energy efficiency, maintaining consistent throughput and response times across large-scale CPS deployments. …”
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Cell-free protein synthesis and vesicle systems for programmable therapeutic manufacturing and delivery by Wonhee Kim, Jinjoo Han, Shraddha Chauhan, Jeong Wook Lee

“…This synergy facilitates the efficient production of complex proteins—including membrane proteins, antibody fragments, and proteins requiring post-translational modifications (PTMs)—and supports novel drug delivery strategies. …”
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Managing acute coccydynia in the ED: A case report of a successful blind sacrococcygeal nerve block by Aakash A. Setty, MD, Stevin M. Bienfait, MD, Jessica C. Oswald, MD

“…Conservative management of NSAIDs, acetaminophen and activity modifications from a prior ED visit failed to improve her symptoms, leaving her requiring significant daily bedrest. …”
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Removal of Pesticides from Aqueous Solutions by Adsorption on Zeolites as Solid Adsorbents by C. De Smedt, F. Ferrer, K. Leus, P. Spanoghe

“…These assumptions are based on the particle size of the adsorbates, the water adsorption on the zeolites and the modifications of the crystal structures.…”
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