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TET dioxygenases localize at splicing speckles and promote RNA splicing
Published 2025-12-01“…Interestingly, though, the oxidation of m5C to hm5C restores splicing efficiency in vitro. The latter highlights the regulatory role of cytosine modifications in RNA metabolism. …”
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744
NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA
Published 2025-08-01“…Abstract N‐acetyltransferase 10 (NAT10)‐catalyzed N4‐acetylcytidine (ac4C) modification has been reported to drive tumor metastasis. …”
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745
Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells.
Published 2015-01-01“…These INH-ODNs were equally or significantly more efficient to impair TLR7- and TLR9-stimulated murine B-cells, macrophages, conventional and plasmacytoid dendritic cells than the parent INH-ODN 2088, which lacks G-modification. …”
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746
Expedient Synthesis of Substituted Thieno[3,2-<i>b</i>]thiophenes and Selenopheno[3,2-<i>b</i>]selenophenes Through Cascade Cyclization of Alkynyl Diol Derivatives
Published 2024-11-01“…Using this strategy, substitution patterns were obtained for backbone modification in functional materials.…”
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Public health services: implementation of healthcare technologies
Published 2020-10-01Get full text
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750
Magnetic Ferrites Synthesized from Leclanché Exhausted Batteries for Heavy Metal Detection
Published 2025-05-01“… The pervasive presence of heavy metals in the environment poses significant health risks, necessitating the development of efficient and cost-effective detection methods. This study explores the use of MFe2O4-based nanocomposites, synthesized from exhausted Leclanché cell residues, for the electrochemical detection of heavy metals such as Cu2+, Hg2+, Pb2+, and Sn2+. …”
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751
Current status and advances in zinc anodes for rechargeable aqueous zinc-air batteries
Published 2025-12-01“…The goal of this review is to inspire new research directions and promote the development of more efficient zinc anodes.…”
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High-Efficiency DNA Extraction Using Poly(4,4′-Cyclohexylidene Bisphenol Oxalate)-Modified Microcrystalline Cellulose-Magnetite Composite
Published 2019-01-01“…The results confirmed the successful modification of the polymer surface. On testing in the presence of three types of binding buffers, a high value of 72.4% (out of 10,000 ng/μL) efficiency with a total yield of DNA at 2×106 ng and absorbance ratio of A260/A280 (1.980) was observed for the 2 M GuHCl/EtOH binding buffer. …”
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Escaping endogenous miRNA post-transcriptional silencing of JrGRF4b enhanced transformation efficiency in woody plants
Published 2025-06-01“…The results showed that escaping endogenous miRNA regulation by targeted site modification of rJrGRF4b significantly improved transgene performance in woody plants. …”
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759
New Approaches to Developing the Integral Indicator Methodology for Estimating the Financial Efficiency of Agricultural Entities in Poland, the Republic of Moldova, and EU Countrie...
Published 2019-12-01“…Economic literature pays a great deal of attention to economic and financial efficiency, expressed in terms of competition, concentration, productivity and profitability. …”
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760
CdS/CeO2/Ag2CO3 nanocomposite as an efficient heterogeneous catalyst for Knoevenagel condensation and acetylation reactions
Published 2025-05-01“…Abstract Knoevenagel condensation and acetylation reactions play a critical role in organic synthesis by facilitating the formation of carbon-carbon bonds and the modification of functional groups; however, limitations like low efficiency and demanding reaction conditions and time underscore the necessity for developing better techniques to enhance their practical applications. …”
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