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681
Iron oxide nanoparticles enhancing magnetic resonance imaging: A review of the latest advancements
Published 2025-06-01“…This review examines diverse surface engineering strategies, including protein, polysaccharide, polymer, lipid, mesoporous silica, and hybrid coatings, that enhance biocompatibility, circulation time, and targeting efficiency. Despite their potential, IONPs face challenges in clinical translation, including regulatory hurdles, inconsistent targeting efficiency, and long-term safety concerns. …”
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682
Research on Interfacial Bonding Property of Modified Fiber Reinforced Concrete and Present Situation Analysis
Published 2022-01-01“…The hydration evolution process,microstructure,and modification mechanism of the matrix in concrete under multi-mineral and polymer hybrid modification need to be studied immediately.Optimal modification methods for different fibers should be proposed according to economical efficiency,construction technology,and modification effect.…”
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683
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An optimized protocol for in vitro regeneration and genetic transformation of broomcorn millet
Published 2025-08-01“…The transformation efficiency was 21.25% after our modification approach. …”
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685
Ways to increase the regenerative potential of mesenchymal stromal cells
Published 2023-10-01“…The development of these approaches opens the way to increasing the efficiency of using MSCs in regenerative medicine.…”
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686
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687
Identification and Characterization of the RNA Modifying Factors PUS7 and WTAP as Key Components for the Control of Tumor Biological Processes in Renal Cell Carcinomas
Published 2025-04-01“…Such chemical modifications directly influence fundamental properties such as transcript stability, alternative splicing, and translation efficiency, all of which are basic requirements for (tumor) cell proliferation, cell metabolism, cell migration, apoptosis resistance, etc. …”
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688
Adhesion, proliferation and viability of human umbilical vein endothelial cells cultured on the surface of biodegradable non-woven matrices modified with RGD peptides
Published 2019-05-01“…The arginine–glycine–aspartic acid (RGD) sequence (a cell adhesion site that is present on many extracellular matrix proteins) is the promising target for modification. The efficiency of attachment of endothelial cells can be influenced both by the structure of RGD peptide and the extent of linker group.Aim: to determine the optimal method for modification of non-woven matrices of polyhydroxybutyrate/ valerate and polycaprolactone (PHBV/PCL) by RGD-peptides leading to the increasing of adhesion, viability and proliferation of endothelial cells.Materials and methods. …”
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689
Characterizing transcripts of HIV-1 different substrains using direct RNA sequencing
Published 2024-10-01“…Post-transcriptional processing and modification of viral RNA, including alternative splicing, polyadenylation, and methylation, play crucial roles in regulating viral gene expression, enhancing genomic stability, and increasing replication efficiency. …”
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690
Optimization of Hydrogen Combustion in Diesel Engines: A CFD-Based Approach for Efficient Hydrogen Mixing and Emission Reduction
Published 2025-04-01“…The novelty of this research lies in the specific modifications made to optimize engine performance and reduce emissions while utilizing the existing Diesel engine infrastructure. …”
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691
Optimizing HDAC inhibitors to enhance HDR-associated CRISPR-Cas9 gene editing efficiency in vivo and in vitro
Published 2025-03-01“…Gene editing by CRISPR-Cas9 via homology-directed repair (HDR) offers precise and desirable modifications, but its low efficiency remains a challenge due to the dominance of the non-homologous end joining (NHEJ) pathway in DNA repair. …”
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692
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693
Enhancing Energy Efficiency of Hydrodealkylation (HDA) Toluene for Benzene Production through Optimizing Utility Tool (Pinch Analysis)
Published 2024-12-01“…The results of the analysis and calculations, the utility modifications in the heat exchanger network system have proven to have a positive impact on energy efficiency and overall performance. …”
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694
Supramolecular force-driven non-fullerene acceptors as an electron-transporting layer for efficient inverted perovskite solar cells
Published 2025-02-01“…Herein, we develop two Y-type NFAs, Y-Phen and Y-CE, by substituting the benzothiadiazole core of Y6 with higher-polarity phenanthroline and crown ether. These modifications effectively enhance carrier kinetics by (1) promoting ordered molecular assembly on the perovskite surface through supramolecular interactions, thereby optimizing interfacial energetic alignment, and (2) improving the molecular packing to facilitate efficient charge transport. …”
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695
Fluorine-induced gradient electric field in mesoporous covalent organic frameworks for efficient separation of polarized perfluorinated gases
Published 2025-07-01“…This study highlights the significance of strategically modifying pore surface chemistry based on the polarizability differences of guest molecules. Such modifications enable the efficient separation of mixed gas molecules in mesoporous materials.…”
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696
Improving Energy Efficiency in Sulfuric Acid Production from Sulfur and Air by Adding Heat Exchanger and Reducing Cooler
Published 2025-06-01“…The sulfuric acid production process uses a contact process which is carried out with 3 reaction stages where the raw materials in the form of sulfur and free air are reacted in the reactor and SO2 gas is obtained, then SO2 reacts with oxygen to form SO3 gas in the converter bed, and finally the formation of H2SO4 from the reaction between SO3 and water in the absorber column. Modifications were made using Aspen HYSYS to improve energy efficiency in the sulfuric acid production. …”
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697
Three-dimensional analysis of thermohydraulic performance in corrugated channels with embedded baffles: Optimization of heat transfer and energy efficiency
Published 2025-05-01“…This study conducts a three-dimensional thermohydraulic analysis of wavy channels equipped with embedded baffles on the upper wall, aiming to optimize heat transfer while minimizing pressure losses. The efficiency of heat exchangers is crucial in many industrial applications, and research efforts have focused on improving their performance through geometric modifications. …”
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698
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699
An efficient and accurate numerical method for simulating close-range blast loads of cylindrical charges based on neural network
Published 2025-02-01“…To address the problems of low accuracy by the CONWEP model and poor efficiency by the Coupled Eulerian-Lagrangian (CEL) method in predicting close-range air blast loads of cylindrical charges, a neural network-based simulation (NNS) method with higher accuracy and better efficiency was proposed. …”
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700