Rescue of the disease-associated phenotype in CRISPR-corrected hiPSCs as a therapeutic approach for inherited retinal dystrophies by Laura Siles, Esther Pomares

“…Homozygous mutations and point insertions/deletions resulted in the highest homology-directed repair efficiencies, with at least half of the clones repaired properly without off-target effects. …”
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Platinum-Functionalized Hierarchically Structured Flower-like Nickel Ferrite Sheets for High-Performance Acetone Sensing by Ziwen Yang, Zhen Sun, Yuhao Su, Caixuan Sun, Peishuo Wang, Shaobin Yang, Xueli Yang, Guofeng Pan

“…Here, platinum (Pt)-functionalized layered flower-like nickel ferrite (NiFe₂O₄) sheets were efficiently fabricated via facile hydrothermal synthesis and wet chemical reduction processes. …”
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Epithelial-mesenchymal transition in colorectal cancer metastasis and progression: molecular mechanisms and therapeutic strategies by Fangfang Nie, Xue Sun, Jizhuo Sun, Jingdong Zhang, Yuanhe Wang

“…This review systematically examines the molecular mechanisms regulating EMT in CRC, including key transcription factors; post-translational and epigenetic modifications; non-coding RNAs; and pivotal signaling pathways. …”
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Pectin-carbonate hydroxyapatite composite films as a potential drug delivery system for cinnamaldehyde: Characterization and release kinetics modeling by Nisaul Fadilah Dalimunthe, Sang Kompiang Wirawan, Michael Michael, Thiodorus Marvin Tjandra, Muhammad Thoriq Al Fath, Rivaldi Sidabutar

“…This innovative approach not only addresses the challenges of sustainable and efficient oral drug delivery systems but also offers potential in structurally superior delivery system with targeted and sustained drug release capabilities.…”
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Stable Multipoint Flux Approximation (MPFA) Saturation Solution for Two-Phase Flow on Non-K-Orthogonal Anisotropic Porous Media by Pijus Makauskas, Mayur Pal

“…This work provides a reliable and efficient tool for simulating coupled flow and transport processes, with applications in CO₂ storage, hydrogen storage, geothermal energy, and hydrocarbon recovery.…”
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Guidelines for implementing cleaner production strategies in a natural rubber gloves manufacturing industry by Muthukannan M, S. Saravanakumar, M.T. Sambandam, Umapathi K, R. Kamalakannan

“…The audit results for all different equipment are included in the report, along with suggested modifications and energy-saving achieved. The findings are still applicable as of the date and duration of the visit to the facility. …”
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The NSL complex regulates housekeeping genes in Drosophila. by Kin Chung Lam, Friederike Mühlpfordt, Juan M Vaquerizas, Sunil Jayaramaiah Raja, Herbert Holz, Nicholas M Luscombe, Thomas Manke, Asifa Akhtar

“…We find that an increased abundance of the histone modifications H4K16ac, H3K4me2, H3K4me3, and H3K9ac in gene promoter regions is characteristic of NSL-targeted genes. …”
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Sign-Entropy Regularization for Personalized Federated Learning by Koffka Khan

“…Theoretically, we frame SER as an information-theoretic and geometric regularizer that stabilizes learning dynamics without requiring dual-model structures or communication modifications. This work opens avenues for trajectory-based regularization and hybrid entropy-guided optimization in federated and resource-constrained learning settings.…”
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Strange features are no better than no features: predator recognition by untrained birds by Ondřej Fišer, Irena Strnadová, Petr Veselý, Michaela Syrová, Michal Němec, Barbora Kamišová, Josef Šalom, Roman Fuchs

“…The shrikes attacked the unmodified dummy kestrel more intensively than both kestrel modifications when defending the nest. However, shrikes did not show different responses to the kestrel with pigeon key features and the featureless kestrel. …”
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Cell-free protein synthesis and vesicle systems for programmable therapeutic manufacturing and delivery by Wonhee Kim, Jinjoo Han, Shraddha Chauhan, Jeong Wook Lee

“…This synergy facilitates the efficient production of complex proteins—including membrane proteins, antibody fragments, and proteins requiring post-translational modifications (PTMs)—and supports novel drug delivery strategies. …”
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Managing acute coccydynia in the ED: A case report of a successful blind sacrococcygeal nerve block by Aakash A. Setty, MD, Stevin M. Bienfait, MD, Jessica C. Oswald, MD

“…Conservative management of NSAIDs, acetaminophen and activity modifications from a prior ED visit failed to improve her symptoms, leaving her requiring significant daily bedrest. …”
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Removal of Pesticides from Aqueous Solutions by Adsorption on Zeolites as Solid Adsorbents by C. De Smedt, F. Ferrer, K. Leus, P. Spanoghe

“…These assumptions are based on the particle size of the adsorbates, the water adsorption on the zeolites and the modifications of the crystal structures.…”
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Automated Morphology Detection of Nail-Fold Capillaries Through Enhanced Object Detection Network by Hang Thi Phuong Nguyen, Hieyong Jeong

“…These modifications yielded a notable improvement in mean Average Precision at IoU 0.50 (mAP@50), with increases of 3.7% in mAP, 3.6% in precision, and 2.5% in recall compared to the baseline YOLOv8 model. …”
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Leveraging the Electronic Health Record to Measure Resident Clinical Experiences and Identify Training Gaps: Development and Usability Study by Vasudha L Bhavaraju, Sarada Panchanathan, Brigham C Willis, Pamela Garcia-Filion

“…ObjectiveThis study aims to demonstrate a feasible and efficient method to capture electronic health record (EHR) data that measure the volume and variety of pediatric resident clinical experiences from a continuity clinic; generate individual-, class-, and graduate-level benchmark data; and create a visualization for learners to quickly identify gaps in clinical experiences. …”
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More is more: Addition bias in large language models by Luca Santagata, Cristiano De Nobili

“…This bias should be con-sidered in the development and application of LLMs to ensure balanced and efficient problem-solving approaches.…”
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Evaluation of Amine Functionalized Thermal Power Plant Solid Waste for Industrial Wastewater Remediation by Ali Y. Kozbek, Kubilay Şahin, Ertuğrul Sarı, Esra Bedir, Fatma G. Yüce, Senem Çitoğlu, Hatice Duran

“…The maximum adsorption efficiencies of APTES coated micro/nanoparticles for MO and XO dye molecules were calculated to be around 98% and 75%, respectively. …”
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Radiative cooling textiles using industry-standard particle-free nonporous micro-structured fibers by Catrysse Peter B., Fan Shanhui

“…At present, however, radiative cooling has received insufficient attention in commercial design and production of textiles for wearable garments. Textiles that efficiently transmit the radiative heat were recently demonstrated, but either do not utilize standard weaving and knitting processes for wearable garments or require substantial process modifications. …”
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Balancing central control and sensory feedback produces adaptable and robust locomotor patterns in a spiking, neuromechanical model of the salamander spinal cord. by Alessandro Pazzaglia, Andrej Bicanski, Andrea Ferrario, Jonathan Arreguit, Dimitri Ryczko, Auke Ijspeert

“…Moreover, intermediate feedback strengths expand the stability region of the network, enhancing its tolerance to a wider range of descending drives, internal parameters' modifications and noise levels. Conversely, high values of feedback strength lead to a loss of controllability of the network and a degradation of its locomotor performance. …”
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Experimental Investigations on Leakages in Positive Displacement Machines by Hitesh H. Patel, Vikas J. Lakhera

“…The leakage flow through these clearances influences the volumetric and adiabatic efficiencies of the machines. The extent of the leakage flow depends on the size and shape of clearance paths and pressure differences across these paths. …”
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Bioinformatics Analysis of Opioids: Correlating Physicochemical Properties with Pharmacokinetics, Pharmacodynamics, and Molecular Interactions by Alexandra Loredana ALMĂŞAN, Maria MERNEA

“…Based on these findings, structural modifications such as reducing hydrophobic bulk or introducing polar groups could improve opioid selectivity and minimize off-target effects. …”
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