Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms. by Diana Mora-Obando, Davinia Pla, Bruno Lomonte, Jimmy Alexander Guerrero-Vargas, Santiago Ayerbe, Juan J Calvete

“…Antivenomics showed that all the six antivenom affinity matrices efficiently immunoretained most of the B. asper lineages venom proteins and exhibited impaired binding towards the venoms' peptidomes. …”
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Les réseaux d’alimentation en eau des pentes de la Croix-Rousse et de la presqu’île de Lyon by Jules Ramona

“…The thermal complexes of the old Monnaie block and of ZAC Saint-Vincent, as well as the public fountain on Place d’Albon are part of it.Ultimately, the study tells us that all the resources available on the zone were directly and efficiently exploited, whether in public, housing or artisanal contexts. …”
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Hypoxic cancer-associated fibroblast exosomal circSTAT3 drives triple negative breast cancer stemness via miR-671-5p/NOTCH1 signaling by Lu Yang, Siyuan Zhao, Xu Liu, Yuchen Zhang, Shaorong Zhao, Xuan Fang, Jin Zhang

“…Results Hypoxic CAF-derived exosomes efficiently transferred circSTAT3 to TNBC cells, promoting proliferation, migration, EMT, and stemness marker expression. …”
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Sensitivity studies of a four-dimensional local ensemble transform Kalman filter coupled with WRF-Chem version 3.9.1 for improving particulate matter simulation accuracy by J. Lin, J. Lin, T. Dai, L. Sheng, W. Zhang, S. Hai, Y. Kong

“…Smaller root mean square errors and larger correlation coefficients in the analysis of PM<span class="inline-formula">_2.5</span> and PM<span class="inline-formula">₁₀</span> are observed across nearly all verification stations, indicating that the 4D-LETKF assimilation optimizes the simulation of PM<span class="inline-formula">_2.5</span> and PM<span class="inline-formula">₁₀</span> concentration efficiently. Sensitivity experiments reveal that the combination of 48 h of assimilation window length and 40 ensemble members shows the best performance for reproducing the severe haze event. …”
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Numerical Investigations of Flow over Cambered Deflectors at <i>Re</i> = 1 × 10⁵: A Parametric Study by Gang Wang, Zhi Wang, Zhaoqi Jiao, Pihai Gong, Changtao Guan

“…The cambered deflectors in aquacultural facilities are applied to enhance hydrodynamic efficiencies or enable flow fields to be fully developed. …”
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IMPACT OF PARENTING STYLE ON CHILD BEHAVIOR AND GUIDANCE STRATEGIES DURING THE DENTAL TREATMENT by N.V. Yanko, L.F. Kaskova, O.O. Kulai, O.Yu. Andriianova

“…Behavior guidance techniques are used to alleviate anxiety, nurture a positive dental attitude, and perform quality oral health care safely and efficiently for children. The aim of this paper was to study the influence of parenting style on the child`s behaviour and some factors influenced guidance strategies during the dental treatment. …”
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ON POTENTIAL REPRESENTATIONS OF THE DISTRIBUTION LAW OF RARE STRONGEST EARTHQUAKES by M. V. Rodkin, V. F. Pisarenko, Ngo Thi Lu, T. A. Rukavishnikova

“…Moreover they testify also that the 'bend-down' is described by the finite distribution law, i.e. the bend-down occurs more efficiently than it is envisaged in the commonly used model developed by Y. …”
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A Possible Protective Effect of IgA Against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) in Bronchoalveolar Lavage in COVID-19 Patients Admitted to Intensive Care... by Mariantonietta Di Stefano, Lucia Mirabella, Antonella Cotoia, Giuseppina Faleo, Michela Rauseo, Anna Chiara Rizzo, Josè Ramon Fiore, Gilda Cinnella, Gaetano Serviddio

“…Dimeric IgA has been reported to be 10 to 15 times more potent than its equivalent IgG, suggesting that this isotype may be particularly interesting in developing new monoclonal antibodies and/or new vaccines efficiently neutralizing the virus at the mucosal sites. …”
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EEG-fMRI neurofeedback versus motor imagery after stroke, a randomized controlled trial by Simon Butet, Mathis Fleury, Quentin Duché, Elise Bannier, Giulia Lioi, Lou Scotto di Covella, Emilie Lévêque-Le Bars, Anatole Lécuyer, Pierre Maurel, Isabelle Bonan

“…This demonstrates potential for NF in enhancing upper-limb motor recovery more efficiently than MI training.…”
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Garlic-Derived Exosome-Like Nanovesicles: A Promising Natural Nanotherapy for Periodontitis via PHGDH/PI3K/AKT-Mediated Metabolic and Inflammatory Regulation by Yu C, Liu Y, Yu X, Liu J, Cao P, Liu G, Cai Y, Zhang Y, Luan Q

“…In vitro, GaELNs were efficiently internalized by human gingival fibroblasts, significantly enhancing their proliferation, migration, and VEGF expression, while markedly reducing LPS-induced oxidative stress and pro-inflammatory factor expression. …”
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National and provincial burden of lung cancer attributable to fine particulate matter air pollution in China, 1990–2021: a systematic analysis of the Global Burden of Disease Study... by Yixuan Jiang, Peng Yin, Renjie Chen, Haidong Kan, Maigeng Zhou

“…Our findings underscore the need for geographically-tailored and population-specific air pollution control measures, especially for ambient PM2.5, to efficiently reduce lung cancer burden in China. Funding: National Natural Science Foundation of China (82030103), National Key Research and Development Program of China (2022YFC3702701), China Postdoctoral Science Foundation (2023M740649).…”
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Enhancing access to specialist appointments in tertiary healthcare in Shanghai, China: a structured reservation pathway using digital health technologies by Li Li, Tao Zheng, Enhong Dong, Minjie Chen, Xiaojing Zhao, Binyuan Zhang, Xuji Zhao, Weijun Shao, Yiling Fan

“…The programme was designed to efficiently connect patients requiring specialised care with the appropriate medical specialists.Participants The PRP encompassed both voluntary specialists at Renji Hospital, as well as patients seeking outpatient specialist services.Primary outcome measures The pass rates of patient for specialist applications.Secondary outcome measures Clinical department, specialists’ and patients’ characteristics influencing specialist review result.Results From a data set of 58 271 applicants across 26 departments between 1 December 2020 and 30 November 2022, we noted an overall pass rate of 34.8%. …”
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Press Forward: Advancing Vaccine Production With High Hydrostatic Pressure Inactivation for Global Health Equity by Miss Martina Brandolini, Dr Alessandra Mistral De Pascali, Mr Giorgio Dirani, Mr Massimiliano Guerra, Ms Silvia Zannoli, Prof Pietro Rocculi, Dr Michele Morbarigazzi, Dr Davide Lelli, Dr Antonio Lavazza, Dr Francesca Battioni, Prof Monica Cricca, Prof Alessandra Scagliarini, Prof Vittorio Sambri

“…Discussion: Preliminary results show HHP efficacy in producing viral inactivates that can efficiently be used as immunogens in murine animal models. …”
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Effects of gender affirming hormone therapy with testosterone on renal function of assigned female at birth transgender people: a meta-analysis by Daniele Tienforti, Daniele Tienforti, Luca Spagnolo, Luca Piscitani, Camilla Tonni, Vittoria Donatelli, Vittoria Donatelli, Giuliana Cordeschi, Marco Giorgio Baroni, Arcangelo Barbonetti

“…This study aimed to quantify through a meta-analytical approach the changes in estimated glomerular filtration rate (eGFR), a widely used clinical parameter that reflects how efficiently the kidneys filter waste products from the blood, and in secondary markers of kidney functions in this population during 24 months of GAHT. …”
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Integrative physiological and transcriptomic analysis provides insights on the molecular basis of ABA-enhanced drought tolerance in pear (Pyrus betulaefolia) by Guo-Ling Guo, An-Ran Luo, Yun-Hui Tan, Rui-Kang Yuan, Ting-Yue Luo, Pan-Pan Ma, Jun-Yu Zhan, Piao Han, Li Liu, Wei Heng, Zhenfeng Ye, Sheng Yang, Bing Jia

“…Overall, our study reveals that exogenous ABA could help pear plants to efficiently scavenge drought-induced ROS by improving their photosynthesis capacity, ABA accumulation, sugar catabolism, enzymatic antioxidant system, etc. …”
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Developing a Machine Learning Model for Predicting 30-Day Major Adverse Cardiac and Cerebrovascular Events in Patients Undergoing Noncardiac Surgery: Retrospective Study by Ju-Seung Kwun, Houng-Beom Ahn, Si-Hyuck Kang, Sooyoung Yoo, Seok Kim, Wongeun Song, Junho Hyun, Ji Seon Oh, Gakyoung Baek, Jung-Won Suh

“… BackgroundConsidering that most patients with low or no significant risk factors can safely undergo noncardiac surgery without additional cardiac evaluation, and given the excessive evaluations often performed in patients undergoing intermediate or higher risk noncardiac surgeries, practical preoperative risk assessment tools are essential to reduce unnecessary delays for urgent outpatient services and manage medical costs more efficiently. ObjectiveThis study aimed to use the Observational Medical Outcomes Partnership Common Data Model to develop a predictive model by applying machine learning algorithms that can effectively predict major adverse cardiac and cerebrovascular events (MACCE) in patients undergoing noncardiac surgery. …”
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Newborn screening facilitates early theranostics and improved spinal muscular atrophy outcome: five-year real-world evidence from Taiwan by Chen-Hua Wang, Ting-Rong Hsu, Mei-Ying Liu, Li-Yun Wang, I-Jun Chou, Wang-Tso Lee, Wen-Chen Liang, Inn-Chi Lee, Hsiao-Jan Chen, Shu-Min Kao, Hui-Chen Ho, Dau-Ming Niu, Kwang-Jen Hsiao, Ming-Yuh Chang, Hui-Min Hsieh, Yuh-Jyh Jong

“…Implementation of SMA NBS using RT-PCR or MassARRAY platform efficiently led to the detection of neonates with homozygous survival motor neuron 1 (SMN1) deletions at a median age of 9 (range 4–14) days. …”
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Patient-informed outpatient intervention to improve pregnancy outcomes through connections to social services: protocol for the BETTER randomised controlled trial by William A Grobman, Laura J Rush, Ann Scheck McAlearney, Anna Bartholomew, Timothy R Huerta, Sarah R MacEwan, Nicole R Thomas, Lindsey N Sova, Leah Roth, Kaprea F Johnson

“…Maternal anaemia is an upstream factor associated with severe maternal morbidity, maternal mortality and other APOs and is also associated with adverse SDoH. Effectively and efficiently addressing social needs arising from adverse SDoH in the obstetric setting can be difficult due to varying patient preferences, resource accessibility and clinic workflows. …”
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Global biogeography of N₂-fixing microbes: <i>nifH</i> amplicon database and analytics workflow by M. Morando, J. D. Magasin, S. Cheung, S. Cheung, M. M. Mills, J. P. Zehr, K. A. Turk-Kubo

“…Multiple datasets are efficiently and consistently processed with a specialized DADA2 pipeline to identify amplicon sequence variants (ASVs). …”
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Reduced-dose deep learning iterative reconstruction for abdominal computed tomography with low tube voltage and tube current by Shumeng Zhu, Baoping Zhang, Qian Tian, Ao Li, Zhe Liu, Wei Hou, Wenzhe Zhao, Xin Huang, Yao Xiao, Yiming Wang, Rui Wang, Yuhang Li, Jian Yang, Chao Jin

“…Abstract Background The low tube-voltage technique (e.g., 80 kV) can efficiently reduce the radiation dose and increase the contrast enhancement of vascular and parenchymal structures in abdominal CT. …”
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