Cytokines as potential biomarkers for the diagnosis of Mycobacterium bovis infection in Mediterranean buffaloes (Bubalus bubalis) by Giulia Franzoni, Federica Signorelli, Piera Mazzone, Anna Donniacuo, Giovanna De Matteis, Francesco Grandoni, Lorena Schiavo, Susanna Zinellu, Silvia Dei Giudici, Javier Bezos, Javier Bezos, Esterina De Carlo, Giorgio Galiero, Francesco Napolitano, Alessandra Martucciello

“…Improving TB diagnostic performance in this species represents a key step to eradicate efficiently this disease. We have recently shown the utility of the IFN-γ assay in the diagnosis of M. bovis infection in Mediterranean buffaloes (Bubalus bubalis), but other cytokines might be useful immunological biomarkers of this infection. …”
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Combining inhibition of galectin-3 with and before a therapeutic vaccination is critical for the prostate-tumor-free outcome by Carolina Tiraboschi, Lucas Gentilini, Carla Velazquez, Enrique Corapi, Felipe Martín Jaworski, José Daniel Garcia Garcia, Yorfer Rondón, Anne Chauchereau, Diego José Laderach, Daniel Compagno

“…We also used two different methods to inhibit the expression of galectin-3 (Gal-3) in tumor cells: a stable RNA interference method to control the expression of this galectin efficiently only in tumor cells, and low and non-cytotoxic doses of docetaxel to easily transfer our findings to clinical settings.Results Herein, we show for the first time that Gal-3 expressed by prostate tumor cells is the main immune checkpoint responsible for the failure of vaccine-based immunotherapy. …”
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The quadruplex TaqMan MGB fluorescent quantitative PCR method for simultaneous detection of feline panleukopenia virus, feline herpesvirus 1, feline calicivirus and feline infectio... by Haojie Wang, Lihong Xue, Longxi Wang, Yixuan Liu, Jianxing Chen, Yue Sun, Tongqing An, Hongyan Chen, Changqing Yu, Changyou Xia, He Zhang

“…The R² values of standard curves are 0.994, 1.0, 0.998 and 0.999, respectively, and high amplification efficiencies of 105.05%, 96.28%, 98.82%, and 96.45%, respectively. …”
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Circulating Baseline CXCR3+Th2 and Th17 Cell Proportions Correlate With Trabecular Bone Loss After 48 Weeks of Biological Treatment in Early Rheumatoid Arthritis by Julia M. Scheffler, Christina Drevinge, Catharina Lindholm, Inger Gjertsson, Kristina Lend, Merete Lund Hetland, Mikkel Østergaard, Till Uhlig, Marte Schrumpf Heiberg, Espen A. Haavardsholm, Michael T. Nurmohamed, Jon Lampa, Tuulikki Sokka‐Isler, Dan Nordström, Kim Hørslev‐Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Ronald vanVollenhoven, Hans Carlsten, Mattias Lorentzon, Anna‐Karin Hultgård Ekwall, Anna Rudin, Ulrika Islander

“…Conclusion MTX together with bDMARDs efficiently reduce disease activity but only prevent bone loss in a subset of patients with RA after 48 weeks of treatment. …”
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Detection of Cassava Mosaic Disease and Assessment of Selected Agronomic Traits of Cassava (<i>Manihot esculenta</i>) by Musa Decius Saffa, Alusaine Edward Samura, Mohamed Alieu Bah, Angela Obiageli Eni, Ezechiel Bionimian Tibiri, Adama Sagnon, Fidèle Tiendrébéogo, Justin Simon Pita, Prince Emmanuel Norman, Raymonda Adeline Bernardette Johnson

“…The Nuru app is inefficient for phenotypically detecting CMD at 3 months after planting (MAP), while at 6, 9 and 12 MAP, the app efficiently detected the disease using a molecular analysis technique. …”
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One-step diagnosis of infection and lung cancer using metagenomic sequencing by Shaoqiang Li, Yangqing Zhan, Yan Wang, Weilong Li, Xidong Wang, Haoru Wang, Wenjun Sun, Xuefang Cao, Zhengtu Li, Feng Ye

“…Conclusions Onco-mNGS has exhibited exceptional efficiencies in the detection and differentiation of infection and lung cancer. …”
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A potent and broad CD4 binding site neutralizing antibody with strong ADCC activity from a Chinese HIV-1 elite neutralizer by Yingdan Wang, Ping Ji, Qianying Liu, Nannan Jia, Yunping Ma, Tianyi Yuan, Palizhati Rehati, Jiali Chen, Yumei Wen, Fan Wu, Jinghe Huang

“…FD22 bound strongly to HIV-1-infected cell lines, efficiently engaged FcγRIIIa receptors, triggered NK cell degranulation and the release of key cytokines such as IFN-γ and β-chemokines, and robustly induced antibody-dependent cellular cytotoxicity (ADCC) against HIV-1-infected target cells. …”
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A novel machine learning models for meteorological drought forecasting in the semi-arid climate  region by Chaitanya Baliram Pande, Dinesh Kumar Vishwakarma, Aman Srivastava, Kanak N. Moharir, Fahad Alshehri, Norashidah Md Din, Lariyah Mohd Sidek, Bojan Đurin, Abebe Debele Tolche

“…The ensemble method played a novel and crucial role in significantly improving the accuracy of drought forecasting by developing ML models based on various algorithms that operate more efficiently, require fewer inputs, and exhibit less complexity than precise models, proving highly effective for drought warning systems. …”
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Safety and Efficacy of Cinacalcet in Children Aged Under 3 Years on Maintenance Dialysis by Julie Bernardor, Sacha Flammier, Ilona Zagozdzon, Alexander D. Lalayiannis, Linda Koster-Kamphuis, Enrico Verrina, Eiske Dorresteijn, Isabella Guzzo, Dieter Haffner, Rukshana Shroff, Claus P. Schmitt, Justine Bacchetta

“…Conclusion: Cinacalcet efficiently controlled severe sHPT in children aged <3 years and was associated with hypocalcemic episodes (similar to what is observed in older children) and precious puberty, thereby mandating meticulous control of calcium (considering nutrition, supplementation, and dialysate) and endocrine changes.…”
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Perancangan Knowledge Sharing System Untuk Meningkatkan Kinerja Dosen Di Fakultas Teknik Universitas Bangka Belitung by Elyas Kustiawan, Rodiatul Adawiyah, Eka Sari Wijayanti

“…Knowledge sharing requires a technology to run effectively and efficiently. Purpose of this research is to design a knowledge sharing system (KSS) at the Faculty of Engineering, UBB. …”
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Design of an improved model using federated learning and LSTM autoencoders for secure and transparent blockchain network transactions by R. Vijay Anand, G. Magesh, I. Alagiri, Madala Guru Brahmam, Balamurugan Balusamy, Chithirai Pon Selvan, Haya Mesfer Alshahrani, Masresha Getahun, Ben Othman Soufiene

“…Our proposed framework is effective according to the interim outcomes where the aggregation of local models occurred without data leakage, detected anomalies very efficiently, managed models very transparently, with privacy of data at a very high level, and easily detected fraudulent transactions. …”
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In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protoc... by Sara Alonso Fernandez, Raquel Reyes-Manzanas, Susana Camara, Juan Mozas-Gutierrez, Myriam Calle-Rubio, Juan Rodriguez-Hermosa, Andres Bodas-Pinedo, Santiago Rueda Esteban, Esther M Lafuente, Jesús Reiné, Pedro A Reche

“…However, in patients with obstructive respiratory diseases, altered or dysregulated T-cell responses to HRV may not only fail to efficiently eliminate the virus but can also exacerbate inflammation and airway remodeling. …”
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Effects of forage feeding to calves on performance, rumen fermentation, and nutrient digestibility: A meta-analysis by Jianxin Xiao, Jia Tian, Yingqi Peng, Rui Hu, Quanhui Peng, Lizhi Wang, Bai Xue, Zhisheng Wang

“…The results of the mixed-effects model analysis indicated that calves can be efficiently fed 12% of DM as forage during the preweaning period to support their growth and development. …”
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Evaluation of Antioxidant, Xanthine Oxidase-Inhibitory, and Antibacterial Activity of <i>Syzygium cumini</i> Linn. Seed Extracts by Jitendra Pandey, Nitesh Jaishwal, Mamta Jayswal, Deep Chand Gupta, Bishnu Dhakal, David Budean, Gopal Lamichhane, Hari Prasad Devkota

“…Cold maceration was chosen for its ability to preserve thermolabile compounds and efficiently extract bioactive constituents with minimal energy and equipment requirement, with hexane and methanol employed as extraction solvents. …”
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In vitro proparation of pear (Pyrus L.) by Nataliia Kucher, Volodymyr Hrabovyi, Olga Opalko, Volodymyr Zamorskyi, Anatoly Opalko

“…In this variant, the first root in microclones developed in 8–10 days, and after a month, rooting reached 87.50% of P. communis and 98.54 % of P. salicifolia. The efficiencies of both Pyrus species adaptation were better with Ellepress peat plugs, than with Jiffy-7 peat pellets. …”
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Social connections related to health and well-being needs identified by children and adolescents affected by displacement in Lebanon: a participatory research study by Tanvi Jain, Lynsey Cooper, Nicole Khauli, Kathleen Pike, Brigitte Khoury, Sabrina Hermosilla

“…We hypothesize that this unique methodology will identify and describe different social connections by group quickly and efficiently. Methods: An initial scoping review of scientific and grey literature followed by stakeholder interviews identified nutrition, mental health, and abuse scenarios that guided the PATMSC (a mixed- method data collection tool that identifies and visualizes types and qualities of social connections) topics. …”
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Penentuan Musim Penangkapan Ikan Ekor Kuning (Blonch, 1791): Studi Perairan Karimunjawa, Indonesia by Pranata Candra Perdana Putra, Setyo Tri Wahyudi, Abu Bakar Sambah, Aida Sartimbul

“…One approach that can be applied is determining the fishing season index, which considers fishing patterns so that fishing activities can occur effectively and efficiently. This study aims to determine the optimal yellowtail fishing season index using the moving average method based on time series analysis to optimize fishing sustainably. …”
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Pretreatment CT-Based Machine Learning Radiomics Model Predicts Response in Inoperable Stage III NSCLC Treated with Concurrent Radiochemotherapy Plus PD-1 Inhibitors by Ya Li Bachelor, Min Zhang Bachelor, Yong Hu MM, Bo Du Bachelor, Youlong Mo Bachelor, Tianchu He MM, Mingdan Zhao Bachelor, Benlan Li Bachelor, Ji Xia Bachelor, Zhongjun Huang Bachelor, Fangyang Lu MD, Zhen Huang Bachelor, Bing Lu MD, Jie Peng MD

“…Conclusion Pretreatment CT-based radiomics model accurately and efficiently predicts treatment response and risk stratification in patients with unresectable stage III NSCLC treated with concurrent chemoradiotherapy and sequential programmed death-1 inhibitor therapy. …”
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Patients’ and Health Care Professionals’ Perspectives on Remote Patient Monitoring in Chronic Obstructive Pulmonary Disease Exacerbation Management: Initiating Cocreation by Atena Mahboubian, Marise J Kasteleyn, Enna Bašić, Niels H Chavannes, Jiska J Aardoom

“…HCPs reported seeing value in RPM for between-visit monitoring and efficiently allocating resources but stressed the need for clear guidelines and noted barriers, such as language proficiency and technology usability. …”
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A comprehensive water quality assessment for a typical river–lake watershed in Northeast China: implications for the water management of boundary lake by Bingbo Ni, Xuemei Liu, Yanfeng Wu, Ming Jiang, Yuanchun Zou

“…In addition, our systematic approach efficiently identified key water quality indicators from 11 types of indicators, including total nitrogen (TN), total phosphorus (TP), and water temperature (Tw) during the summer-autumn period, and TN and dissolved oxygen (DO) in the winter-spring period. …”
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