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    Effective Dose of Epidural Hydromorphone for Analgesia Following Caesarean Section in Using Modified Dixon Sequential Method by Liu QQ, Mao M, Lin NH, Xu CY, Li Q, Jiang CS, Feng SW, Yuan HM

    Published 2024-11-01
    “…Participants received a single epidural injection of 0.2% ropivacaine 20 mg along with a study dose of hydromorphone. The median effective dose (ED50), 90% effective dose (ED90), and corresponding 95% confidence intervals (CIs) of hydromorphone with ropivacaine for analgesia after caesarean section were calculated using the probit method.Results: The ED90 and ED50 in our population were 1.105 mg (95% CI: 0.825– 2.324 mg) and 0.659 mg (95% CI: 0.434– 0.883 mg), respectively.Conclusion: Epidural hydromorphone can be safely used for postoperative analgesia in patients undergoing caesarean section, and the analgesic effect is satisfactory when the dosage is appropriate.Keywords: hydromorphone, ropivacaine, caesarean delivery, postoperative analgesia, ED50, ED90…”
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    Endoscopic Clot Removal Is an Effective Method for Treating Massive Ruptured Esophageal Hematoma: A Case Report by Jie Li, Manli Cui, Hua Wen, Jie Zhang, Mingxin Zhang

    Published 2025-04-01
    “…Conclusion: Endoscopic clot removal is an effective method of treating esophageal huge hematoma accompanied by rupture. …”
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    A Cost-Effective and Robust Cell-Based Bioassay Method for Evaluating the Bioactivity of Trastuzumab-like Antibodies by Pooja Bharali, Subhash Chand, Harish Chander

    Published 2024-12-01
    “…Bioassay is one of the critical quality attributes (CQAs), hence developing a reliable and robust bioassay is essential for the evaluation of their biological activity and the harmonization of the quality of these biologics, supporting their safe and effective use in clinical practice. <b>Methods:</b> The present study aimed to develop a robust cell-based bioassay to assess the bioactivity of trastuzumab and its biosimilars for quality control testing. …”
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    Validation of a Cost-Effective RP-HPLC Method for Quantitative Investigation of Daclatasvir Dihydrochloride in Pharmaceutical Formulations by Sadaf Sarfraz, Muhammad Saeed, Mohsin Javed, Nadia Hussain, Shahid Iqbal, Shahid Amin, Ali Bahadur, Ahmed Hussain Jawhari, Randa A. Althobiti, Eman Alzahrani, Abd-ElAziem Farouk, Samar O. Aljazzar, Eslam B. Elkaeed

    Published 2023-01-01
    “…Herein, we reported a selective, precise, and a cost-effective analytical method for the measurement of an active pharmaceutical ingredient (API) of daclatasvir dihydrochloride in drug substances as well as drug products via the reversed-phase RP-HPLC technique. …”
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    A new method for diagnosing effective radiative forcing from aerosol–cloud interactions in climate models by B. M. Duran, C. J. Wall, C. J. Wall, N. J. Lutsko, T. Michibata, P.-L. Ma, Y. Qin, M. L. Duffy, M. L. Duffy, B. Medeiros, M. Debolskiy

    Published 2025-02-01
    “…Here, we develop a new, computationally efficient method for estimating the shortwave (SW) ERFaci from liquid clouds using histograms of monthly averaged cloud fraction partitioned by cloud droplet effective radius (<span class="inline-formula"><i>r</i><sub>e</sub></span>) and liquid water path (LWP). …”
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    Teaching Accessible Space in Architectural Education: Comparison of the Effectiveness of Simulated Disability Training and Expert-Led Methods by Agata Bonenberg, Barbara Linowiecka

    Published 2025-03-01
    “…They believe that this method is more ethical and respectful. To explore this debate, the authors of this study compared the two teaching methods. …”
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    Research of the chemical composition of Artemisia tschernieviana Bess. by gas chromatography method with mass detection by O. I. Panasenko, V. I. Mozul, O. M. Denysenko, I. I. Aksonova, V. V. Holovkin

    Published 2021-12-01
    “…The aim of the work was to study chromato-mass spectroscopic of Artemisia tschernieviana Bess. grass and to establish possible prospects for the use of this plant in medical practice. Materials and methods. Artemisia tschernieviana Bess. grass was chosen as the object of research. …”
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    Cost-Reference Particle Filter-Based Method for Constructing Effective Brain Networks: Application in Optically Pumped Magnetometer Magnetoencephalography by Yuyu Ma, Xiaoyu Liang, Huanqi Wu, Hao Lu, Yong Li, Changzeng Liu, Yang Gao, Min Xiang, Dexin Yu, Xiaolin Ning

    Published 2024-12-01
    “…Optically pumped magnetometer magnetoencephalography (OPM-MEG) represents a novel method for recording neural signals in the brain, offering the potential to measure critical neuroimaging characteristics such as effective brain networks. …”
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