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  1. 5241

    Varför ska jag inte berätta? by Jonas Asklund

    Published 2018-11-01
    “…In an intervention study based on a series of book discussions of an easy reader novel, I investigated the cooperation between a group of Swedish language learners aged 16 to 19, their teacher in the introduction program for newcomers, and the school librarian. Based on my function as a teacher educator, and drawing on the current research in literature didactics, I planned and carried out six discussions where different reading strategies and methods were used. …”
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    The Effectiveness of Using the Reggio Emilia Approach on the Experimental Science Lesson for Third-Grade Elementary Students by Batool Sabzeh, Farangis Ghalavand, Seyedamir Ghasemtabar

    Published 2024-03-01
    “…A primary goal of science education is to foster scientific literacy for addressing real-world problems (Krajcik & Czerniak, 2014). …”
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    The impact of sensory integration based sports training on motor and social skill development in children with autism spectrum disorder by Lingtao Wen, Zhixia Wu

    Published 2025-06-01
    “…Sensory integration-based sports training significantly improves motor and social functioning in children with ASD and offers a promising approach for therapeutic and educational rehabilitation programs.…”
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  12. 5252

    Jericho’s Daughters: Feminist Historiography and Class Resistance in Pip Williams’ <i>The Bookbinder of Jericho</i> by Irina Rabinovich

    Published 2025-07-01
    “…By integrating close literary analysis with historical research on women bookbinders, educational reform, and the impact of World War I, the paper reveals how the novel functions as both a narrative of personal development and a broader critique of systemic exclusion. …”
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    An Empirical Study on the Deficiencies and Optimization of the Management System of Tourist Attractions Based on Human Resource Management by Yan Tang, Siran Bai, Lingling Cui

    Published 2022-01-01
    “…Today, with the deepening of economic globalization and the further intensification of competition among enterprises, the role and functions of human resource managers of enterprises have undergone major changes. …”
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  16. 5256

    Selective neoadjuvant therapy of rectal cancer patients (SELREC): study protocol for a European randomised controlled, open, multicentre non-inferiority trial by Markus W Büchler, Lukas Baumann, Peter Schirmacher, Christoph W Michalski, Markus K Diener, Dirk Jäger, Pascal Probst, Mohammed Al-Saeedi, Martin Schneider, Alexis Ulrich, Constantin Schwab, Anja Sander, Christina Klose, Christoph Kahlert, Hans-Ulrich Kauczor, Jürgen Debus, Rosa Klotz, Solveig Tenckhoff, Cosima Engerer, Kristin Uzun-Lang, Caroline Wild, Bruno C Köhler

    Published 2025-06-01
    “…The first secondary endpoint is no/minor low anterior resection syndrome (LARS) score at 2 years after surgery, and further secondary endpoints include survival outcomes and quality of life. Safety analysis involves describing the frequencies of major intervention-specific complications, such as the acute toxicity of n(C)RT according to CTCAE and perioperative morbidity and mortality according to Clavien-Dindo criteria.SELREC is financially supported by the German Federal Ministry of Education and Research.Ethics and dissemination This trial has been prospectively registered in the German Clinical Trials Register.Previously, the study had been approved by the responsible ethics committee of Heidelberg and the local ethics committees of the collaborating institutions before patient enrolment. …”
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    Integrated Multi-Omics Profiling Identifies PDZ-Binding Kinase (PBK) as a Novel Prognostic Biomarker in Hepatocellular Carcinoma by Zhang J, Xu Y, Ni X, Mao Z, Xiao H, Chen M, Lin Y, Pan J, Zhang B, Zhang L, Zheng X, Song G, Ge N

    Published 2025-07-01
    “…Patients exhibiting with combined PBK overexpression and high TMB demonstrated the poorest prognosis. Functional validation confirmed that PBK knockdown significantly inhibited Huh7 cell migration capacity (P &lt; 0.05). scRNA-seq analysis showed PBK-enriched tumors contained elevated proportions of immunosuppressive SPP1(+) macrophages (22.33% vs 6.6%, FDR corrected P &lt; 0.001) and CD8(+) SLC4A10(+) MAIT cells (9.82% vs 4.7%, FDR corrected P &lt; 0.001).Conclusion: PBK synergistically drives HCC progression through three synergistic mechanisms: (1) promoting oncogenic mutation accumulation (eg, TP53), (2) increasing metastatic potential, and (3) reprogramming an immune-suppressive microenvironment enriched for SPP1(+) macrophages and CD8(+)SLC4A10(+) MAIT cells. …”
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    Sustainable development of industrial enterprises in the basis of a new form of economic activity organisation by O. E. Astafyeva

    Published 2021-12-01
    “…The platform education proposed by the author as an organisational and economic activity form is the digital ecosystem component, which is a spatial and temporal environment for the functioning of enterprises. …”
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