Prevalence and comorbidity rates of disruptive mood dysregulation disorder in epidemiological and clinical samples: systematic review and meta-analysis by Xavier Benarous, Hélène Lahaye, Angèle Consoli, David Cohen, Réal Labelle, Jean-Marc Guilé

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Dysregulation of lncRNA TFAP2A‐AS1 is involved in the pathogenesis of pulpitis by the regulation of microRNA‐32‐5p by Mingming Liu, Weijing Jia, Lin Bai, Qiaolin Lin

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Infection of Human Coronary Artery Endothelial Cells by Group B Streptococcus Contributes to Dysregulation of Apoptosis, Hemostasis, and Innate Immune Responses by Claudia Beyrich, Jürgen Löffler, Anna Kobsar, Christian P. Speer, Susanne Kneitz, Martin Eigenthaler

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Elucidating tobacco smoke-induced craniofacial deformities: Biomarker and MAPK signaling dysregulation unraveled by cross-species multi-omics analysis by Yuxin Lin, Hao Li, Shukai Zheng, Rui Han, Kusheng Wu, Shijie Tang, Xiaoping Zhong, Jiasheng Chen

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BBB proteomic analysis reveals that complex febrile seizures in infancy enhance susceptibility to epilepsy in adulthood through dysregulation of ECM-receptor interaction signaling... by Qian Wang, Liangyu Pan, Siruan Chen, Yuyu Zhang, Guangyuan Liu, Yiying Wu, Xia Qin, Panpan Zhang, Wei Zhang, Jianghua Zhang, Dezhi Kong

“…Moreover, MSI analysis uncovered notable changes in differential metabolites, including amino acids and nucleotide-derived neurotransmitters associated with the function of BBB maintaining neuronal homeostasis. Subsequent validation experiments showed that dysregulation of the ECM-receptor interaction signaling pathway exacerbated epilepsy susceptibility in adult mice. …”
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Co-regulation and synteny of GFM2 and NSA2 links ribosomal function in mitochondria and the cytosol with chronic kidney disease by Minjie Zhang, Christer Hogstrand, Paola Pontrelli, Afshan N Malik

“…Increased GFM2 affects mitochondrial function with a disconnect between an increase in certain mitochondrial respiratory proteins but a decrease in cellular respiration. …”
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Functional Involvement of TANK-Binding Kinase 1 in the MyD88-Dependent NF-κB Pathway Through Syk by Han Gyung Kim, Ji Hye Kim, Tao Yu, Jae Youl Cho

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The Role of Exercise on Glial Cell Activity in Neuropathic Pain Management by Willians Fernando Vieira, Caroline C. Real, Daniel Oliveira Martins, Marucia Chacur

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Mechanistic insights into the Bushen Huatan Huoxue Formula and its components in ameliorating obesity-associated polycystic ovary syndrome by Yu-Xin Jin, Hang-Qi Hu, Jia-Cheng Zhang, Yu-Tian Zhu, Hao-Lin Zhang, Xi-Yan Xin, Rui-Wen Fan, Yang Ye, Yin Li, Dong Li

“…In vitro, 3T3-L1 cells were used to assess lipid accumulation, mitochondrial function, and the effects of BHHF-containing serum. …”
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Development of SOCS1 mimetics as novel approach to harmonize inflammation, oxidative stress, and fibrogenesis in metabolic dysfunction-associated steatotic liver disease by Susana Bernal, Ignacio Prieto, María Kavanagh, Isabel Herrero del Real, Sara La Manna, Iolanda Lázaro, Hernán Quiceno, Laura López-Sanz, Belén Picatoste, M. Pilar Valdecantos, Sebastián Mas-Fontao, Aleix Sala-Vila, Ángela M. Valverde, Daniela Marasco, Jesús Egido, Carmen Gómez-Guerrero

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Copy number-based quantification assay for non-invasive detection of PVT1-derived transcripts. by Gargi Pal, Olorunseun O Ogunwobi

“…The non-protein coding gene locus plasmacytoma variant translocation 1 (PVT1) is located at 8q24 and is dysregulated in prostate cancer. PVT1 gives rise to multiple transcripts which may have different functions. …”
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Comprehensive pan-cancer analysis indicates key gene of p53-independent apoptosis is a novel biomarker for clinical application and chemotherapy in colorectal cancer by Jianing Yan, Jingzhi Wang, Min Miao, Yongfu Shao

“…Dysregulated SLFN11 is accompanied by several immune cell infiltrations and immune-related regulators, which can be a promising screening and prognostic biomarker and chemotherapy predictive target for clinical application. …”
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Expression analysis of LINC00671 and LINC01913 long non-coding RNAs in gastric cancer patients and their correlation with EMT markers by Fatemeh Taghavinia, Negin Taghehchian, Iman Salahshourifar, Mohammad Reza Abbaszadegan

“…However, the clinical significance and biological function of many lncRNAs remain unexplored in GC progression. …”
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Identification of YAP regulators through high-throughput screening and NanoBiT-based validation-drug repositioning for cancer therapy by Ji-Youn Lim, Eui-Hwan Choi, Yujeong Kim, Minseong Kim, Dongkyu Choi, Wantae Kim, Boksik Cha

“…Using a NanoBiT-based system, which enables real-time and quantitative measurement of protein interactions, combined with phenotype-based assays in EGFP-YAP-expressing cells, we identified compounds that activate or inhibit YAP function. …”
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Unveiling a novel model of cell senescence-related genes for prognostic assessment and immunotherapeutic insights in gastric cancer by Gang Wang, Yi Wang, Yanyi Xiao, Zhe Lin

“…To authenticate the dysregulated genes identified within our prognostic signature, we conducted real-time quantitative PCR. …”
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Comprehensive Analysis of lncRNA Expression Profile and the Potential Role of ENST00000604491 in Graves’ Disease by Yingzhao Liu, Junli Zou, Juan Xu, Xuehua Wang, Jie Xing, Li Wang, Huiyong Peng

“…Long noncoding RNAs (lncRNAs) are widely expressed in multiple human diseases and have pivotal functions in gene regulation. This study is aimed at determining the lncRNA profile in peripheral blood mononuclear cells (PBMCs) from GD patients and investigating the role of ENST00000604491 in GD. …”
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Mmu_circ_0000037 inhibits the progression of acute pancreatitis by miR‐92a‐3p/Pias1 axis by Hua Chen, Jun Tu, Lei He, Ning Gao, Weiqiang Yang

“…This study aimed to investigate the function and regulatory mechanism underlying mmu_circ_0000037 in caerulein‐induced AP cellular model. …”
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Cell based high-throughput screening for small molecule inhibitors of ATE1 by Claudia McCown, Evan A. Ambrose, Devang M. Patel, Hassan Al-Ali, Louis Scampavia, Fangliang Zhang, Timothy P. Spicer

“…Arginyltransferase 1 (ATE1) catalyzes post-translational arginylation, a process implicated in protein stability, cellular function, and disease pathology. Dysregulated arginylation is associated with neurodegenerative disorders, cancer, and inflammation. …”
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LncRNA of peripheral blood mononuclear cells: HYMAI acts as a potential diagnostic and therapeutic biomarker for female major depressive disorder by Tianyi Bu, Jiarun Yang, Jiawei Zhou, Yeran Liu, Kexin Qiao, Yan Wang, Jili Zhang, Erying Zhao, Boakye Kwame Owura, Xiaohui Qiu, Zhengxue Qiao, Yanjie Yang

“…Then, the potential biomarker was screened out by quantifying differentially expressed lncRNAs based on quantitative real-time PCR. To further investigate the function of biomarkers in the pathogenesis of MDD, bioinformatics analysis on downstream target genes was carried out.ResultsThe expression profile screened out 300 differentially expressed lncRNAs. …”
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Overexpression of ST8Sia1 inhibits tumor progression by TGF-β1 signaling in rectal adenocarcinoma and promotes the tumoricidal effects of CD8+ T cells by granzyme B and perforin by Chang Zhang, Yeli Wang, Yao Yu, Yanchao Pang, Xiao Xiao, Leilei Hao

“…Furthermore, the expression of ST8Sia1 in tissues was analyzed using real-time quantitative polymerase chain reaction (RT-qPCR), western blotting (WB), and immunohistochemistry (IHC). …”
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