Dementia with lewy bodies patients with high tau levels display unique proteome profiles by Sinead Greally, Mukesh Kumar, Christoph Schlaffner, Hanne van der Heijden, Elisabeth S. Lawton, Deeptarup Biswas, Sabina Berretta, Hanno Steen, Judith A. Steen

“…We conducted proteomic analysis to characterize and compare the cortical proteome of DLB subjects exhibiting elevated tau, as well as the molecular modifications of tau and α-synuclein to explore the dynamic between tau and α-synuclein pathology in these patients. …”
Get full text

Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…This is due to various factors, some within control and others influenced by complex global political and economic environments. A comparative analysis reveals several weaknesses in Iran's tourism supply chain that need to be addressed. …”
Get full text

Cryo-Rolled AA5052 Alloy: Insights into Mechanical Properties, Formability, and Microstructure by Arun Achuthankutty, Rohith Saravanan, Hariesh Nagarajan, Vidyanand Pasunuri, Nishanth Hari Gopal, Ajith Ramesh, Sumesh Arangot, Dinu Thomas Thekkuden

“…The study sheds light on the ways that solutionizing, cryo-rolling, and annealing interact to affect the alloy’s mechanical characteristics. Microstructure analysis shows that solutionizing improves the grain structure by reducing dynamic recovery, promoting dislocation density, and facilitating precipitate formation. …”
Get full text

Evaluation of thermal effects in high-speed shifting tillage operations on share-point wear in sandy loam soil by Yan-Chen Li, Dan-Yang Song, Lin Zhu, Xin-Yu Xie, Xin-Ran Wu, Hao-Ran Wang, Lu Liu

“…This paper extended our previous work to evaluate the thermal effects by using a combined multi-body dynamics analysis (MDA) and fluid–solid-thermal simulation. …”
Get full text

Development of operational decision support tools for mechanized ski guiding using avalanche terrain modeling, GPS tracking, and machine learning by J. Sykes, J. Sykes, P. Haegeli, R. Atkins, P. Mair, Y. Bühler, Y. Bühler

“…The overall accuracies of the models are 84.6 %, 91.9 %, and 93.3 % respectively compared to a testing dataset of roughly 20 000 observed run codes. …”
Get full text

Performance Evaluation Model of Overhead Transmission Line Anti-Icing Strategies Considering Time Evolution by Xuyang Li, Xiaojuan Xi, Zhengwei Guo, Yongjie Li, Muzi Li, Bing Fan

“…Implementation cost is treated as risk control expenditure, and strategy performance is assessed by integrating it with residual risk cost to identify the optimal strategy through composite cost analysis. The proposed model enables a comprehensive assessment of anti-icing strategy performance, improving the accuracy of strategy selection and achieving a dynamic balance between implementation cost and transmission line reliability. …”
Get full text

LASSIM-A network inference toolbox for genome-wide mechanistic modeling. by Rasmus Magnusson, Guido Pio Mariotti, Mattias Köpsén, William Lövfors, Danuta R Gawel, Rebecka Jörnsten, Jörg Linde, Torbjörn E M Nordling, Elin Nyman, Sylvie Schulze, Colm E Nestor, Huan Zhang, Gunnar Cedersund, Mikael Benson, Andreas Tjärnberg, Mika Gustafsson

“…Next, we performed novel time-series measurements of total T-cells during differentiation towards Th2 and verified that our LASSIM model could monitor those data significantly better than comparable models that used the same Th2 bindings. In summary, the LASSIM toolbox opens the door to a new type of model-based data analysis that combines the strengths of reliable mechanistic models with truly systems-level data. …”
Get full text

Establishing an Immune System Conferring DNA and RNA Virus Resistance in Plants Using CRISPR/Cas12a Multiplex Gene Editing by Lili Luo, Liqing Miao, Xuhui Ma, Jinjin Hu, Suzhen Li, Wenzhu Yang, Shuai Ma, Rumei Chen, Xiaoqing Liu

“…We quantified TMV virus accumulation in the transgenic N. benthamiana lines by monitoring dynamic changes in GFP fluorescence and quantitative analysis by qPCR showed that the CRISPR‐Cas12a system can introduce TMV virus resistance to N. benthamiana by preventing its systemic spread. …”
Get full text

THE ROLE OF AMBIDEXTERITY IN MEDIATING ENTREPRENEURIAL ORIENTATION AND BUSINESS PERFORMANCE IN SMES by Indra Prasetyo, Rusdiyanto Rusdiyanto, Nur Fadjrih Asyik, Nabilah Aliyyah, Rahmat Luthfi Haidar, Adiba Fuad Syamlan

“…The data underwent rigorous analysis using Structural Equation Modelling (SEM), facilitated by SmartPLS software, to yield robust and comprehensive insights. …”
Get full text

TBFH: A Total-Building-Focused Hybrid Dataset for Remote Sensing Image Building Detection by Lin Yi, Feng Wang, Guangyao Zhou, Niangang Jiao, Minglin He, Jingxing Zhu, Hongjian You

“…We evaluated the effectiveness of TBFH on multiple state-of-the-art models, including UNet, UNetFormer, ABCNet, BANet, FCN, DeepLabV3, MANet, SegFormer, and DynamicVis. Our comparative experiments conducted on the Tall Building dataset, the WHU dataset, and TBFH demonstrated that models trained with TBFH significantly outperformed those trained on individual datasets, showing notable improvements in IoU, F1, and KTC scores as well as in the accuracy of building shape delineation. …”
Get full text

Molecular Fractionation Induced by Viscosity-Driven Segregative Phase Separation Behavior of Gum Arabic/Hydroxypropyl Methylcellulose by Lingyu Han, Cunzhi Zhang, Nuo Dong, Jixin Yang, Qiuyue Zheng, Xiaobo Zhang, Ronggang Liu, Jijuan Cao, Bing Hu

“…By conducting a comparative analysis of two GA subtypes (CGA and SGA) and three HPMC grades with controlled viscosity gradients, we utilized gel permeation chromatography-multi-angle laser light scattering (GPC-MALLS) coupled with rheological characterization to elucidate the critical relationship between continuous phase viscosity and fractionation efficiency. …”
Get full text

Effects of Near-Fault Pulse-Like Ground Motion on Seismic Response of Dry Sand Site by LIU Hongshuai, SONG Dongsong, DONG Xinyi, WANG Tiqiang

“…NFPLGMs significantly increased PGD compared to FFGMs, while NFNPGMs slightly reduced it. …”
Get full text

Development of the automated system for assessing radiation risks to the population of the Russian Federation based on the data of radiation-hygienic certification of territories by R. R. Akhmatdinov, A. M. Biblin, L. V. Repin

“…Automation of the calculation of radiation risk allows not only to simplify the calculation procedure but also to carry out a spatial-temporal analysis of risk in dynamics for different regions of the Russian Federation over long periods. …”
Get full text

Structural Brain Morphometry in Children with Attention Deficit Hyperactivity Disorder and Comorbid Mild Cognitive Impairments by George A. Karkashadze, Alexey I. Firumyants, Nikita S. Shilko, Nataliya S. Sergienko, Yulia V. Nesterova, Leonid M. Yatsyk, Elena N. Rudenko, Mikhail I. Polle, Tatiana A. Salimgareeva, Tinatin Yu. Gogberashvili, Nataliya E. Sergeeva, Tatiana A. Konstantinidi, Safarbegim Kh. Sadilloeva, Marina A. Kurakina, Viktor V. Dyachenko, Inessa A. Povalyaeva, Evgeniy V. Bogdanov, Anastasia I. Rykunova, Elena A. Vishneva, Elena V. Kaytukova, Kamilla E. Efendieva, Leyla S. Namazova-Baranova

“…The aim of the study is to determine and perform comparative analysis of MR-morphometric brain parameters in children with ADHD depending on the presence or absence of comorbid mild cognitive impairments. …”
Get full text

Preparing Future Teachers for the Digitalization of Preschool Education by A. I. Klimina, O. V. Krezhevskikh

“…To solve the tasks, a set of complementary research methods was used: theoretical (analysis of sources on the research topic; specification of data; generalization of psychological and pedagogical literature; comparison of data on this issue; deduction; meaningful interpretation and analysis of results) and empirical (conducting ascertaining, formative and control experiments; questionnaires; testing; analysis of products of  activity (performing practical tasks, essays); qualitative, quantitative and statistical methods of processing the obtained results based on a comparative analysis of the Mann-Whitney U test, Student’s t-test). …”
Get full text

Factors Influencing Background Parenchymal Enhancement in Breast Contrast-Enhanced Mammography: A Retrospective Study by Xue J, Qu T, Li Z, Shi B, Yang G, Rong X, Li Y, Lin G, Ping Y

“…BPE on subtracted CEM images was assessed quantitatively (region of interest [ROI] analysis of pixel values) and qualitatively (subjective classification). …”
Get full text

R&D Expenditure and Innovation in the EU and Selected Member States by Radka MacGregor Pelikánová

“…Such a conglomerate of diversified and multi-disciplinary data is to be processed by a myriad of appropriately matching methods, both of a quantitative and qualitative nature, and dominated by the holistic Meta-Analysis. …”
Get full text

The Effect of Mepolizumab on Blood Eosinophil Subtype Distribution and Granule Protein Gene Expression in Severe Eosinophilic Asthma by Rimkunas A, Januskevicius A, Vasyle E, Palacionyte J, Kalinauskaite-Zukauske V, Miliauskas S, Malakauskas K

“…Gene expression investigation was done using quantitative real time-polymerase chain reaction analysis.Results: Approximately three-quarters of isolated blood eosinophils were iEOS-like cells before mepolizumab treatment, p< 0.01. …”
Get full text

Development of empirical correlations for sustainable breakup characterization of water and high-viscous oil sheets under acoustic perturbations using high-speed imaging by Aman Singh, Devesh T, Subhash K, Preetam Polavarapu, Jayakrishnan Rahul, Karthick S, Balaji K

“…Subsequently, quantitative analysis has been carried out to the formulate breakup stability empirical results. …”
Get full text

FUNCTIONAL STATE OF THE MASTICATORY MUSCLES OF PATIENTS WITH DEFECTS OF DENTITION, WHICH ARE COMPLICATED BY DENTOALVEOLAR DEFORMITIES by O. V. Bida, Yu. I. Zabuha

“…In particular, prolongation of chewing time, change of chewing rhythm and reduction of chewing efficiency are observed in patients with dentition defects, which are complicated by dentoalveolar deformations compared with the norm. Especially, noticeable changes occur within a single dynamic loop (activity rest) in time figures of bioelectrical activity and the ratio between the excitatory and inhibitory processes are rapidly deteriorating, increase the term of bioelectric activity by reducing the period of relative rest bioelectrical. …”
Get full text