Managing the Effects of Drug Use through Evidence-Based Measures by Paula-Ștefania FRUSINOIU, Anda SAMSON, Cristian-Silviu BĂNACU

“…There are several causes or factors that contribute to the complex phenomenon of drug use and abuse. …”
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Molecular insights into ion and water transport in cementitious pore structures by Yuying Duan, Heping Zheng, Shaochun Li, Pan Wang, Dongshuai Hou, Yongjuan Geng

“…The durability of concrete is a crucial factor influencing its long-term performance and safety, with the transport properties of water and ions in cement hydration products playing a key role in this process. …”
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The 1st Baltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 2016. Summary and Consensus Statements: Group I - Peri-Implantitis Aetiolo... by Claudio Stacchi, Mindaugas Pranskunas, Lukas Poskevicius, Gintaras Juodzbalys, Ricardas Kubilius, Ryo Jimbo, Federico Berton, Giuseppe Perinetti, Andrea Frassetto, Teresa Lombardi, Aiman Khoury, Francesca Andolsek, Roberto Di Lenarda, Julius Maminskas, Algirdas Puisys, Ritva Kuoppala, Aune Raustia, Zygimantas Guobis, Ingrida Pacauskiene, Inesa Astramskaite, Pedro de Sousa Gomes, Maria-Helena Fernandes

“…Introduction: The task of Group 1 was to review and update the existing data concerning aetiology, risk factors and pathogenesis of peri-implantitis. Previous history of periodontitis, poor oral hygiene, smoking and presence of general diseases have been considered among the aetiological risk factors for the onset of peri-implant pathologies, while late dental implant failures are commonly associated with peri-implantitis and/or with the application of incorrect biomechanical forces. …”
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CURRENT METHODS OF ENDOTHELIAL DYSFUNCTION ASSESSMENT AND THEIR POSSIBLE USE IN THE PRACTICAL MEDICINE by A. V. Shabrov, A. G. Apresyan, A. L. Dobkes, S. U. Ermolov, T. V. Ermolova, S. G. Manasyan, S. V. Serdyukov

“…A review contains a description of the most common methods of evaluation and monitoring of "endothelial dysfunction" that are assessed in terms of their information content and applicability in the practice of medicine. The term "endothelial function" is interpreted primarily as a function of the regulation of capillary blood flow, carried out by the expense of the dynamic change of the phase of vasoconstriction and vasodilatation in vessels of resistive type (in accordance with the changing needs of cellular metabolism). …”
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Integrated FEM-Multibody Co-Simulation of Additively Manufactured Hip Prosthesis containing cracks by Roberto Di Bona, Domenico Gentile, Giuseppe Peter Vanoli, Gabriel Testa, Sara Ricci

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IMPACT OF STATE HEALTH PREVENTION FINANCING PROGRAMS ON THE ACTIVITIES OF HEALTH PROTECTION ENVIRONMENTS IN UKRAINE by Raisa Nikitenko, Hanna Panchenko, Oksana Dulina, Viktoriya Latysheva, Orysia Liubinska

“… The article examines the features of the application of correlation-regression analysis to identify the impact of state health prevention financing programs on the activities of health protection entities in Ukraine. …”
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In Silico and In Vitro Studies to Explore the Effect of Thymoquinone on Isocitrate Lyase, Biofilm Formation, and the Expression of Some Virulence Genes in <i>Candida albicans</i> by Masood Alam Khan, Mohd Azam, Hina Younus

“…Additionally, TQ disrupted the yeast-to-hyphae switch, a key virulence factor, with 1 and 2 µg/mL doses significantly inhibiting hyphal formation. …”
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Multicentral Agent-Based Model of Six Epidemic Waves of COVID-19 in the Nizhny Novgorod Region of Russian Federation by A. V. Hilov, N. V. Saperkin, O. V. Kovalishena, N. A. Sadykova, V. V. Perekatova, N. V. Perekhozheva, D. A. Kurakina, M. Ju. Kirillin

“…To investigate the characteristics of the COVID-19 pandemic and introduce timely and effective measures, there is a need for models that can predict the impact of various restrictive actions or characteristics of disease itself on COVID-19 spread dynamics. Employing agent-based models can be attractive because they take into consideration different population characteristics (e.g., age distribution and social activity) and restrictive measures, laboratory testing, etc., as well as random factors that are usually omitted in traditional modifications of the SIR-like dynamic models. …”
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Rural Pakistan’s smokeless tobacco epidemic: a need for tailored interventions by Ziaur Rahman Khan, Syed Jaffar Abbas Zaidi, Sania Riaz, Usman Mahboob, Sana Mirza, Fizza Khalid, Ushnah Imran

“…Results Four major themes emerged: (1) Dynamics of addiction, including peer influence, familial patterns, and stress-related coping; (2) Risk perception, spanning awareness of oral cancer risk yet persistent usage; (3) Cessation journey, highlighting withdrawal challenges, emotional dependency, and limited professional support; and (4) Socioeconomic factors, notably the economic burden on households and calls for stricter regulation. …”
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Effect of tool angle in nanocutting of single crystal GaN using diamond cutter by Yongqiang WANG, Hao XIA, Zhihang HU, Shuaiyang ZHANG, Shaohui YIN

“…MethodsTo achieve these objectives, a rigorous multi-scale investigation is conducted, combining molecular dynamics simulation with experimental verification. …”
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The effect of gamification on brand co-creation in app-based businesses: investigating the mediating role of consumer engagement and the moderating role of hedonic and innovativene... by Rayhane Rezagholizade, Zahra Sadeqi-Arani, Esmail Mazroui

“…Findings indicate that both Snapp and TAPSI's applications incorporate elements of gamification, such as game mechanics and dynamics. …”
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Coherent phenomena in exciton–polariton systems by Federico Toffoletti, Elisabetta Collini

“…Their ability to sustain macroscopic quantum coherence, alongside their sensitivity to environmental and system-engineering factors, highlights their potential for advancing both fundamental quantum science and practical applications, including nanophotonics, energy harvesting, and quantum technologies. …”
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Analysing fluid flow and heat transfer comparatively in flow passage systems: Evaluating thermal impacts and geometric configurations by Farhan Lafta Rashid, Asseel M.Rasheed Al-Gaheeshi, Mudhar A. Al-Obaidi, Hayder I. Mohammed, Hussein Togun, Ephraim Bonah Agyekum

“…The main aim is to evaluate the impacts of different geometric characteristics on the velocity, pressure, and temperature profiles inside the flow route. These factors encompass cavity dimensions, tube diameter, and input conditions. …”
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Flow regime transitions in flow blurring injection through a CFD parametric study by S. Amirreza S. Madani, Erfan Vaezi, Mohammad Reza Morad, Amir Keshmiri

“…Screening analysis of a full factorial design of 32 cases shows that liquid mass flow rate and dynamic viscosity are the most influential factors in penetration length. …”
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Geometric Effects on Nanopore Creation in Graphene and on the Impact-withstanding Efficiency of Graphene Nanosheets by Sadegh Sadeghzadeh

“…Here, the impact-withstanding efficiency of graphene nanosheets and the primary factors affecting creation of nanopores in these sheets were studied using a molecular dynamics method. …”
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Research on Multi-Mass Safety Braking Model for Heavy-Haul Trains Based on Random Distribution of Parameters by BAI Jinlei, WANG Yue, JIANG Fan, ZHANG Zhengfang, SHI Ke, ZHONG Puhua

“…Its key technical feature lies in a new safety braking model developed based on the concept of "dynamic tracking". However, existing research only addresses boundary issues such as emergency braking and minimum headways, lacking applicability in the context of heavy-haul trains, due to the absence of solutions for complex track conditions, strong dispersion in air braking capability, and other unfavorable factors. …”
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Machine learning-aided discovery of T790M-mutant EGFR inhibitor CDDO-Me effectively suppresses non-small cell lung cancer growth by Rui Zhou, Ziqian Liu, Tongtong Wu, Xianwei Pan, Tongtong Li, Kaiting Miao, Yuru Li, Xiaohui Hu, Haigang Wu, Andrew M. Hemmings, Beier Jiang, Zhenzhen Zhang, Ning Liu

“…Abstract Background Epidermal growth factor receptor (EGFR) T790M mutation often occurs during long durational erlotinib treatment of non-small cell lung cancer (NSCLC) patients, leading to drug resistance and disease progression. …”
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Cohort profile: the open, prospective Community-Based chronic Care Lesotho (ComBaCaL) cohort – design, baseline chronic disease risk factors and hypertension and diabetes care casc... by Matthias Briel, Thilo Burkard, Ravi Gupta, Frédérique Chammartin, Alain Amstutz, Thabo Ishmael Lejone, Eleonora Seelig, Irene Ayakaka, Mosa Tlahali, Matumaole Bane, Makhebe Khomolishoele, Tristan Lee, Niklaus Daniel Labhardt, Felix Gerber, Giuliana Sanchez-Samaniego, Thesar Tahirsylaj, Fabian Raeber, Mamakhala Chitja, Malebona Mathulise, Thuso Kabi, Mosoetsi Mokaeane, Malehloa Maphenchane, Manthabiseng Molulela, Mota Mota, Sesale Masike, Retselisitsoe Makabateng, Mamoronts’ane Sematle, Lebohang Sao, Sejojo Phaaroe, Malitaba Litaba, Madavida Mphunyane, Dave Brian Basler, Kevin Kindler, Pauline Grimm

“…In this study, we present the cohort’s sociodemographic and chronic disease risk factor profile, including self-reported HIV prevalence and hypertension and diabetes care cascades.Participants Since February 2023, community health worker (CHWs) supported by a clinical decision support and data collection application have enrolled inhabitants from 103 randomly selected rural villages in Butha-Buthe and Mokhotlong districts in Northeast Lesotho. …”
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Multi-Layers Composite Plasma Coatings Based on Oxide Ceramics and M-Croll by F. I. Panteleenko, V. A. Okovity, O. G. Devоino, V. M. Astashinsky, F. Switala

“…The paper considers the influence of the parameters of the plasma spraying process on the technological characteristics of multilayer coatings based on nickel-chromium, nickel-chromium-aluminum-yttrium materials, oxide ceramics,  intended for operation at high temperature and additional dynamic loads. The design of plasma coatings during their application (with subsequent high-energy processing) under such conditions requires a comprehensive solution – both the use  of high-quality powder ingredients and the optimization of technological parameters. …”
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Beyond structural domains: the emerging roles of PDLIM2 in cellular signaling and cancer progression by Yulian Shi, Yulian Shi, Yulian Shi, Yulian Shi, Tingyu Fan, Tingyu Fan, Tingyu Fan, Tingyu Fan, Yuchao Yang, Yuchao Yang, Yuchao Yang, Yuchao Yang, Jiaxuan Liu, Jiaxuan Liu, Jiaxuan Liu, Jiaxuan Liu, Jun Ouyang, Jun Ouyang, Jun Ouyang, Jun Ouyang, Jingxing Dai, Jingxing Dai, Jingxing Dai, Jingxing Dai

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