Bile acids as a key target: traditional Chinese medicine for precision management of insulin resistance in type 2 diabetes mellitus through the gut microbiota-bile acids axis by Yu Wang, Jing Yu, Binqin Chen, Binqin Chen, Wenqi Jin, Meili Wang, Xuenan Chen, Mengqiong Jian, Mengqiong Jian, Liwei Sun, Chunli Piao

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A new high-resolution hydrodynamic model for the coastal Beaufort Sea in the Arctic Ocean: model construction and evaluation by J. Blake Clark, J. Blake Clark, Wesley Moses, Ahmed El-Habashi, Maria Tzortziou, Kyle J. Turner, Hisatomo Waga, Hisatomo Waga, Steven Ackelson, Jonathan Sherman, Jonathan Sherman

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IMPLEMENTATION OF THE DBSCAN ALGORITHM FOR CLUSTERING STUNTING PREVALENCE TYPOLOGY IN WEST JAVA, CENTRAL JAVA, AND EAST JAVA REGIONS by Bagus Sumargo, Kadir Kadir, Dena Safariza, Munawar Asikin, Dania Siregar, Nilam Novita Sari, Danu Umbara, Rizky Hilmianto, Robert Kurniawan, Irman Firmansyah

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Accurate modeling and simulation of the effect of bacterial growth on the pH of culture media using artificial intelligence approaches by Suleiman Ibrahim Mohammad, Hamza Abu Owida, Asokan Vasudevan, Suhas Ballal, Shaker Al-Hasnaawei, Subhashree Ray, Naveen Chandra Talniya, Aashna Sinha, Vatsal Jain, Ahmad Abumalek

“…Key input variables for the models included bacterial type, culture medium type, initial pH, time (hours), and bacterial cell concentration, all critical to pH dynamics. Sensitivity analysis using Monte Carlo simulations revealed bacterial cell concentration as the most influential factor, followed by time, culture medium type, initial pH, and bacterial type. …”
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Assessment of the Diversity of Medico-Magic Knowledge on Four Herbaceous Species in Benin by Hubert Olivier Dossou-Yovo, Valentin Kindomihou, Fifanou Gbèlidji Vodouhè, Brice Sinsin

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Safe drilling technology for ultra-deep gas wells with complex pressure systems using managed pressure and gas-venting density reduction by LI Tao, YANG Zhe, CHI Chongrong, NIE Zunhao, XU Zhikai, CHEN Xun, WANG Fei

“…The gas influx rate was identified as the main factor affecting well control safety. To ensure safe operations, the gas influx rate must not exceed the critical safe threshold. …”
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Construction of a risk prediction model for pulmonary infection in patients with spontaneous intracerebral hemorrhage during the recovery phase based on machine learning by Jixiang Xu, Yuan Li, Fumin Zhu, Fumin Zhu, Xiaoxiao Han, Liang Chen, Yinliang Qi, Yinliang Qi, Xiaomei Zhou, Xiaomei Zhou

“…The integration of SHAP enhances clinical applicability by demystifying complex model outputs, thereby supporting individualized preventive strategies. …”
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Impact of External Conditions on the Desorption and Degradation Capacity of Biochar for Rhodamine B by Chenghong Ao, Mai Shan, Yue Zhang, Xiang Li, Ying Kong, Xinwei Dong, Yang Liu, Danping Wu

“…Biochar has attracted considerable interest owing to its high adsorption capacity; however, the mechanisms through which environmental factors influence the release of adsorbed pollutants remain unclear. …”
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ODEP-Based Robotic System for Micromanipulation and In-Flow Analysis of Primary Cells by Joanna Filippi, Paola Casti, Valentina Lacconi, Gianni Antonelli, Michele D’Orazio, Giorgia Curci, Carlo Ticconi, Rocco Rago, Massimiliano De Luca, Alessandro Pecora, Arianna Mencattini, Steven L. Neale, Luisa Campagnolo, Eugenio Martinelli

“…The presence of cellular defects of multifactorial nature can be hard to characterize accurately and early due to the complex interplay of genetic, environmental, and lifestyle factors. With this study, by bridging optically-induced dielectrophoresis (ODEP), microfluidics, live-cell imaging, and machine learning, we provide the ground for devising a robotic micromanipulation and analysis system for single-cell phenotyping. …”
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Phenotypic and Genomic Insights into <i>Schleiferilactobacillus harbinensis</i> WU01, a Candidate Probiotic with Broad-Spectrum Antimicrobial Activity Against ESKAPE (<i>Enterococc... by Chonticha Romyasamit, Komwit Surachat, Nawanwat C. Pattaranggoon, Pinkanok Suksabay, Uttapol Permpoon, Tae-Gyu Nam, Phoomjai Sornsenee

“…The combined results highlight its potential application in functional foods and therapeutic interventions.…”
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Small Scale Multi-Object Segmentation in Mid-Infrared Image Using the Image Timing Features–Gaussian Mixture Model and Convolutional-UNet by Meng Lv, Haoting Liu, Mengmeng Wang, Dongyang Wang, Haiguang Li, Xiaofei Lu, Zhenhui Guo, Qing Li

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A Marine-Derived Steroid from <i>Rhodococcus</i> sp., 3,12-Dioxochola-4,6-dien-24-oic Acid, Enhances Skin Re-Epithelialization and Tissue Repair by Mücahit Varlı, Hui Tan, Chaeyoung Lee, Jeongyun Lee, Ji Young Lee, Jeong-Hyeon Kim, Songyi Lee, Hangun Kim, Sang-Jip Nam

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Heat Transfer Analysis of 2D Steady Laminar Mixed Convection CNTs Blood base Nanofluid Flow over a Stretching Surface: Analytical Simulation by Ali Rehman, Ma Chau Khun, Dolat Khan, Arshad Jan

“…With the significant advancements in nanofluids, the fields of fluid dynamics and thermal management have experienced further development. …”
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Model-assisted analysis on the response of tomato fruit growth to source-sink ratio regulated by water and nitrogen by Huiping Zhou, Jinliang Chen, Shaozhong Kang

“…Water and nitrogen (N) are essential factors affecting the tomato plant-fruit system. However, little is known about to what extent water and N could regulate the water and carbon fluxes between the source-sink system, thus influencing fruit growth. …”
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A machine learning based estimation method of beach slopes at a national scale: a case study of New Zealand by Hao Xu, Nan Xu, Chi Zhang, Shanhang Chi, Yuan Li, Wenyu Li, Yifu Ou, Jiaqi Yao, Han-Su Zhang, Fan Mo, Hui Lu

“…We also emphasized that our method can estimate beach slopes for beaches without topography data based on constructed machine learning methods and environmental factors. Future studies should focus on incorporating additional environmental covariates, and extending the model’s applicability to diverse coastal environments, thereby enhancing its predictive accuracy and utility, supporting sustainable coastal development worldwide.…”
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Source-sink foliar boron (10B) mobility modulated by carbohydrate synthesis and confers antioxidative defense in sugar beet (Beta vulgaris L.) under water deficit conditions by Md. Shah Newaz Chowdhury, Britta Pitann, Md. Sazzad Hossain, Karl H. Mühling

“…However, linking B translocation dynamics and drought-mitigating factors is largely unknown. …”
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Effect of gas extraction on mitigating low-oxygen conditions in upper corners and its impact on coal spontaneous combustion in goaf by LIU Gang, CHU Tingxiang, ZHU Tianru, ZHANG Xi, WANG Yufan, MENG Jinwei

“…Gas extraction technology, as an effective measure to mitigate oxygen deficiency in upper corners of shallow coal seam working faces, may lead to an increased risk of coal spontaneous combustion due to elevated air leakage in the goaf during its application. Working face 19112 of No.1 mine at China Coal Pingshuo Group Co., Ltd. was taken as the research object. …”
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Impacts of diffusion and chemical reaction on heat transfer in Casson nanofluids flow over a flat plate with accretion by J. Jayaprakash, Vediyappan Govindan

“…We explore new territory in fluid dynamics by considering accretion with the factors such as non-linear velocity, momentum, thermal and concentration gradients, convection, Grashof effects, diffusion and chemical reactions that have not been thoroughly examined in prior studies despite their obvious relevance.…”
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NEW APPROACHES TO THERAPY OF CLASSICAL PH-NEGATIVE MYELOPROLIFERATIVE DISEASES: THE EXPERIENCE OF EARLY THERAPY WITH CEPEGINTERFERON ALPHA-2B by A. S. Polyakov, Y. A. Noskov, V. V. Tyrenko, A. S. Lapshova, A. V. Kovalev

“…In all groups, a hematologic response comparable in depth and dynamics, as well as a molecular response as a steady decrease in the JAK2V617F allelic load, was achieved. …”
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Exploring the molecular characteristics of inflammatory bowel disease from the perspective of hypoxia-related genes by Lei Zheng, Lin Mou, Lingying Hao, Rui Chen, Yifei Wang, Miao Yu, Xueyan Zhang

“…Immune infiltration analysis revealed substantial disparities in 13 distinct immune cell populations when comparing high-risk and low-risk cohorts.ConclusionsIn summary, this investigation underscores the pivotal function of HRGs in IBD's pathogenesis and introduces a reliable DM grounded in these genetic factors. The findings accentuate the relevance of hypoxia-responsive pathways in IBD and enhance understanding of immune cell dynamics across differing risk profiles. …”
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