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Discovery Patterns of Drugs Approved for Treating Bipolar Disorder by Applying Operational Criteria of Serendipity: A Historical Analysis
Published 2024-01-01“…On the contrary, the recognition of the mood-stabilizing attributes of lamotrigine aligns with the type III archetype. This particular pattern is defined by serendipity emerging as a consequence of a discovery that was initially nonserendipitous, as mood-stabilizing efficacy was incidentally observed during the treatment of epileptic patients for whom the drug was originally developed. …”
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1602
Gene expression noise in spatial patterning: hunchback promoter structure affects noise amplitude and distribution in Drosophila segmentation.
Published 2011-02-01“…We identify means by which noise is controlled during gene expression by characterizing the dependence of hb mRNA and protein output noise on hb promoter structure and transcriptional dynamics. …”
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Unveiling biogeographical patterns of the ichthyofauna in the Tuichi basin, a biodiversity hotspot in the Bolivian Amazon, using environmental DNA.
Published 2022-01-01“…We sampled eDNA from water in 34 sites in lakes and rivers in the Beni basin including 22 sites in the Tuichi sub-basin, during the dry season. To assess the biogeographical patterns of the amazonian ichthyofauna, we implemented a metabarcoding approach using two pairs of specific primers designed and developed in our laboratory to amplify two partially overlapping CO1 fragments, one of 185bp and another of 285bp. …”
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Inter-city movement pattern of notifiable infectious diseases in China: a social network analysisResearch in context
Published 2025-01-01“…Methods: To characterize the migration patterns of major notifiable infectious diseases (NIDs) during 2016–2020 in China, we collected migratory cases, who had illness onset in one city but were diagnosed and reported in another, from the National Notifiable Infectious Disease Reporting System, and conducted a nationwide network analysis of migratory cases of major NIDs at the city (prefecture) level. …”
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Cluster Analysis of RF-EMF Exposure to Detect Time Patterns in Urban Environment: A Model-Based Approach
Published 2025-01-01“…This study addresses the gap by applying model-based clustering techniques to analyze the temporal patterns. Specifically, the study focuses on characterizing fluctuations in field strength during workdays and holidays, thereby contributing to a deeper understanding of time-distributed exposure. …”
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Pattern recognition in SARS cases: insights from t-SNE and k-means clustering applied to COVID-19 symptomatology
Published 2025-03-01“…The study focused on symptoms, case progression, and diagnoses of SARS-CoV-2 and unspecified SARS cases using data from the Brazilian SARS dataset for São Paulo State during 2020 and 2021. The process began with a visual analysis aimed at identifying structural patterns in the symptom data, highlighting potential similarities between COVID-19 patients and those diagnosed with unspecified SARS. …”
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Effects of footwear and foot strike patterns on patellofemoral joint and Achilles tendon loading in novice runners and experienced runners
Published 2025-06-01“…Therefore, novice runners need to gradually adjust their foot strike pattern according to the loading capacity of different joints to reduce the corresponding injury risk.…”
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Pattern of the First Recurrence Has No Impact on Long-Term Survival after Curative Intent Surgery for Perihilar Cholangiocarcinomas
Published 2018-01-01“…Aim. To explore the pattern of the first recurrence and impact on long-term survival after curative intent surgery for perihilar cholangiocarcinomas (PHC). …”
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Spatiotemporal Dynamics of Fish Density in a Deep-Water Reservoir: Hydroacoustic Assessment of Aggregation Patterns and Key Drivers
Published 2025-04-01“…Understanding spatiotemporal patterns of fish density and their environmental drivers is critical for managing river–lake ecosystems, yet dynamic interactions in heterogeneous habitats remain poorly quantified. …”
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Integrating territorial pattern changes into the relationship between carbon sequestration and water yield in the Yangtze River Basin, China
Published 2025-01-01“…Abstract Territorial pattern plays an important role in regional ecosystem management and service provision. …”
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Prevalence and Pattern of Internet Addiction among Adolescents in a Holiday Camp in Nigeria Post-COVID-19 Pandemic
Published 2024-07-01“…Objective: To determine the prevalence and pattern of IA among adolescents in a holiday camp in Nigeria post-COVID-19 pandemic. …”
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Non-Dipping Pattern Is Associated with Periprocedural Myocardial Infarction in Hypertensive Patients Undergoing Elective Percutaneous Coronary Intervention
Published 2025-04-01“…<i>Background and Objectives</i>: Non-dipping blood pressure (BP) patterns are associated with increased cardiovascular risk, but their role in periprocedural myocardial infarction (PMI) during elective percutaneous coronary intervention (PCI) remains insufficiently clarified. …”
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Smartphone and tablet use pattern in children up to 5 years old in Spain: a cross-sectional study
Published 2024-11-01“… Objective: to characterize the smartphones and tablets use pattern in a sample of children up to 5 years old and assess with which variables it is associated. …”
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Intimate partner violence among pregnant women in Anambra State, Nigeria: Prevalence, pattern, determinants and coping strategies
Published 2024-10-01“…Aims This study aimed to assess the prevalence, patterns and determinants of IPV amongst pregnant women attending antenatal care (ANC) at a tertiary hospital in Anambra State, Nigeria. …”
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Mask-wearing behavior patterns among dental patients in post-pandemic China: a cross-sectional study
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Temporal and Spatial Pattern of Expressway Construction in China from 1999 to 2019 and Its Correlation with Regional Economic Growth
Published 2024-11-01“…While total GDP demonstrates balanced development, per capita GDP displays a more varied pattern of growth. (3) Expressway density has played a positive role in fostering regional economic growth across the country over the long term. …”
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