P-14 DETECTION OF CIRRHOSIS DUE TO ALPHA-1 ANTITRYPSIN DEFICIENCY IN ADULTS: PHENOTYPE STUDY IN COSTA RICA by Fernanda Vásquez Carit, Francisco Hevia Urrutia, Jorge Vargas Madrigal, Mildred Jiménez Hernández, Natassia Camacho Matamoros, Danny Alvarado Romero, Jorge Herrera Corrales

“…This disease does not follow an autosomal recessive inheritance pattern, so the classical concept of homozygosity does not apply. …”
Get full text

Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine. by Sarah E Belisle, Jiangmei Yin, Devon J Shedlock, Anlan Dai, Jian Yan, Lauren Hirao, Michele A Kutzler, Mark G Lewis, Hanne Andersen, Simon M Lank, Julie A Karl, David H O'Connor, Amir Khan, Niranjan Sardesai, Jean Chang, Lauri Aicher, Robert E Palermo, David B Weiner, Michael G Katze, Jean Boyer

“…We observed that the RANTES-adjuvanted animals were significantly better at suppressing viral replication during chronic infection and exhibited a distinct pattern of gene expression which included immune cell-trafficking and cell cycle genes. …”
Get full text

Long-term trends in specialized outpatient health care utilization: an analysis in the context of a primary health care reform by Hannes Kohnke, Andrzej Zielinski, Anders Beckman, Henrik Ohlsson

“…Conclusion This study provides key insights into long-term trends in outpatient SHC utilization during a time period that overlaps with the Patient Choice Reform. …”
Get full text

PEMANFAATAN DATA SATELIT HIMAWARI 8 UNTUK MENDETEKSI SEBARAN ASAP: STUDI KASUS DI KALIMANTAN DAN SUMATERA TANGGAL 8 DAN 9 SEPTEMBER 2015 by Ayu Vista Wulandari, Ni Kadek Trisna Dewi, Wishnu Agum Swastiko

“…The distribution of smoke can be seen as an image with the brownish pattern which partially covered the area of Borneo and Sumatera. …”
Get full text

Experimental study on nonlinear hygroscopic and strength behavior of mudstone under coupled temperature and humidity conditions for underground engineering by Weisheng Zhao, Lijun Han, Shuai Yan, Wei He

“…Additionally, coefficient of variation (CV) analysis was conducted to examine water content deviations during the hygroscopic process. The results indicated that the equilibrium water content (EWC) exhibited a three-stage growth pattern with increasing humidity: rapid growth (0‒20% RH), slow growth (20‒60% RH), and accelerated growth (60‒100% RH), whereas it decreased with increasing temperature, although the rate of decrease slowed progressively. …”
Get full text

Factores de riesgo aterosclerótico durante el climaterio by Dania Amalia Álvarez Blanco, Magnolia Aguilera Guethon, Zonia Rojas Benítez, Luis Enrique Vidal Gámez

“…The questionnaire was used according to the Pattern of Gathering of the Primary Fact (MRDP) of the Center of Investigation and Reference of Atherosclerosis of Havana (CIRAH) as well as the patients´s clinical history. …”
Get full text

Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates. by Linda J Porrino, James B Daunais, Gary A Rogers, Robert E Hampson, Sam A Deadwyler

“…Concomitant measures of regional cerebral metabolic rates for glucose (CMRglc) during the task, utilizing positron emission tomography, revealed increased activity in prefrontal cortex, dorsal striatum, and medial temporal lobe (including hippocampus) that was significantly enhanced over normal alert conditions following administration of CX717. …”
Get full text

Modeling Hourly Productivity of Advanced Practice Clinicians in the Emergency Department by Bryan A. Stenson, Peter S. Antkowiak, David T. Chiu, Leon D. Sanchez, Joshua W. Joseph

“…Conclusion: The productivity of APCs demonstrates a similar pattern of hourly declines observed in both resident and attending physicians. …”
Get full text

Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. by Chaitali Misra, Nita Sachan, Caryn Rothrock McNally, Sara N Koenig, Haley A Nichols, Anuradha Guggilam, Pamela A Lucchesi, William T Pu, Deepak Srivastava, Vidu Garg

“…Mice homozygous for the Gata4 G295S mutant allele have normal ventral body patterning and heart looping, but have a thin ventricular myocardium, single ventricular chamber, and lethality by E11.5. …”
Get full text

Relationships between Sleep Duration, Timing, Consistency, and Chronotype with Myopia among School-Aged Children by Rong Li, Yiting Chen, Anda Zhao, Lili Huang, Zichong Long, Wenhui Kang, Yong Yin, Shilu Tong, Shenghui Li

“…Sleep duration and timing, mainly during weekdays, were correlated with myopia in a dose-dependent pattern, in which longer sleep duration was associated with decreased risk of myopia (9-10 hours/day: odds ratio (OR) = 0.87; ≥10 hours/day: OR = 0.77; by comparison with <9 hours/day); later bedtime (9 pm to 9:30 pm: OR = 1.46; 9:30 pm to 10 pm: OR = 1.51; 10 pm and after: OR = 2.08; by comparison with before 9 pm) and later wake-up time (7 am and after: OR = 1.36; by comparison with before 6:30 am) increased the risk (all P<0.05). …”
Get full text

A COMBINATION TECHNIQUE OF AUTOLOGOUS AUGMENTATION AND BREAST LIFTING IN HYPOPLASTIC-THIRD GRADE PTOTIC BREAST: A CASE REPORT by Beta Subakti Nataatmadja, Nida' Fahima Amatullah, Loelita Marcelia Lumintang

“…Discussion: Breast tissue changes a lot during and after pregnancy and hormonal factors increases the risk of ptosis. …”
Get full text

Review of Cross-Leg Flaps in Reconstruction of Posttraumatic Lower Extremity Wounds in a Microsurgical Unit by Ravi K. Mahajan, Krishnan Srinivasan, Harish Ghildiyal, Mahipal Singh, Adish Jain, Taha Kapadia, Ankush Tambotra

“…The location of defect in the leg, the indication for cross-leg flap, the pattern of cross-leg flap, and perioperative complications were noted. …”
Get full text

Case Report: A family of congenital cataract caused by a novel mutation in the CRYGC gene c.52G>A by Shuying Ma, Yao Lu, Xiao Shao, Qingyan Liu, Xin Yin, Min Xue

“…Notably, this genetic variant was absent in unaffected family members.ConclusionThe patients in this pedigree exhibited an autosomal dominant inheritance pattern, with all affected individuals presenting bilateral lens opacities unaccompanied by systemic abnormalities, confirming a definitive diagnosis of congenital cataracts. …”
Get full text

Hepcidin knockout exacerbates hindlimb unloading-induced bone loss in mice through inhibiting osteoblastic differentiation by Xin Chen, Jianping Wang, Chenxiao Zhen, Gejing Zhang, Zhouqi Yang, Youjia Xu, Peng Shang

“…Astronauts who are exposed to weightlessness during prolonged spaceflight experience bone loss. …”
Get full text

Association of whole grain food consumption with lung cancer risk: a prospective cohort study by Kanran Wang, Junhan Zhao, Dingyi Yang, Mao Sun, Yongzhong Wu, Wei Zhou

“…A linear dose-response pattern was shown for lung cancer, NSCLC, and SCLC (P for non-linearity > 0.05). …”
Get full text

A new domestic herbicide for weed control in maize crops ‘Metkiy, MD’ by Kh. Sh. Tarchokov, D. A. Tutukova, O. Kh. Mataeva

“…By the period of grain harvesting, this pattern had no changes. During this period there were up to 75.0 specimens and 800.0 g/m2 of wet weight of weeds. …”
Get full text

Morphological features of the major duodenal papilla in patients with cholelithiasis by V. M. Klymenko, D. V. Syvolap, S. I. Tertishniy

“…Material and methods. During autopsies, selection of fragments of major duodenal papilla from 30 dead was performed. …”
Get full text

Competitiveness of Polish service exports in the EU: A focus on specialisation in the years 2010-2022 by Elżbieta Bombińska

“…Based on traditional service industries, the pattern of competitive advantages in Polish service exports was characterised by relatively little differentiation across the main EU export markets. …”
Get full text

Effect of Land Use Activities on Water Quality and Vegetation Cover Change in Nsooba-Lubigi Wetland System, Kampala City by Charles K. Twesigye, Kennedy Igunga, Ritah Nakayinga

“…The Total Nitrogen average value for built-upareas (11.27 mg/l) was higher than the national standard of 10 mg/l while the remainingland use types of wetland (8.05mg/l) and agriculture (5.96mg/l) were below that of therecommended standard.GIS and Remote sensing techniques were used to analyze high-resolution satellite imagery captured during 1998, 2008 and 2018. Wetland coveragedeclined by approximately 5 hectares (47.2% to 14.58%) from1998 to 2018. …”
Get full text

Sustainable groundwater control system for environmental and geotechnical problems in Sabkha soils in arid regions: case study from Abu Dhabi Metropolitan area by Ahmed Sefelnasr, Mohsen Sherif, Zainab Alhosani, Hamad Abduallah, Ahmed Baobaid, Abdel Azim Ebraheem

“…The rapid urban expansion during the last twenty years, along with the development of extensive green areas in and around Abu Dhabi City, has exacerbated the waterlogging problem in urban areas. …”
Get full text