Assessing the role of genotype by environment interaction of winter wheat cultivars using envirotyping techniques in North China by Haiwang Yue, Yanbing Wang, Zhaoyang Chen, Jiashuai Zhu, Partha Pratim Behera, Pengcheng Liu, Haoxiang Yang, Jianwei Wei, Junzhou Bu, Xuwen Jiang, Xuwen Jiang, Wujun Ma

“…Accurate yield estimation depends on understanding the patterns of GEI in multi-environment trials (METs).MethodsFrom 2014 to 2018, continuous experiments were conducted in the Heilonggang region of the North China Plain (NCP), evaluating 71 winter wheat genotypes across 16 locations over five years. …”
Get full text

Cropland encroachment on ecological land in Mainland Southeast Asia leads to massive carbon emissions by Danni Su, Kun Yang, Zongqi Peng, Run Sun, Mingfeng Zhang, Xiaofang Yang, Lusha Ma, Jingcong Ma

“…This study simulated MSEA’s land use patterns under SSP1-RCP2.6, SSP2-RCP4.5, and SSP5-RCP8.5 using the PLUS model with data from 1992 to 2022. …”
Get full text

Annual dialysis data report 2022, Japanese Society for Dialysis Therapy (JSDT) Renal Data Registry by Norio Hanafusa, Masanori Abe, Nobuhiko Joki, Junichi Hoshino, Masatomo Taniguchi, Kan Kikuchi, Takeshi Hasegawa, Shunsuke Goto, Tetsuya Ogawa, Eiichiro Kanda, Shigeru Nakai, Toshihide Naganuma, Kenichiro Miura, Atsushi Wada, Yoshiaki Takemoto

“…The number of incident dialysis patients during 2022 was 39,683, showing a decrease of 828 from 2021. …”
Get full text

Analysis of ROH Characteristics Across Generations in Grassland-Thoroughbred Horses and Identification of Loci Associated with Athletic Traits by Wenqi Ding, Wendian Gong, Tugeqin Bou, Lin Shi, Yanan Lin, Xiaoyuan Shi, Zheng Li, Huize Wu, Manglai Dugarjaviin, Dongyi Bai

“…Using the SNP dataset, we analyzed the number and length distribution patterns of runs of homozygosity (ROHs) in the genomes of different generational groups of Grassland-Thoroughbreds. …”
Get full text

Changing trends in oral mucosal diseases in China (2016–2024): a cross-sectional study of 316,166 patients with focus on COVID-19 impact and use of chinese patent medicines by Peiru Zhou, Xu Zhang, Yifan Chen, Jiakun Fang, Yanhong Meng, Furong Yang, Pan Wei, Hong Hua

“…The study found significant differences in disease patterns among age groups, with oral potentially malignant disorders like oral lichen planus becoming more prevalent in older populations. …”
Get full text

Socioeconomic determinants potentially underlying differential global SARS-CoV-2 testing capacity: an ecological study by Michael Knipper, Andres Moreira-Soto, Carl Beuchel, Ximena Tabares, Ben Wulf, Nils Gade, Carlo Fischer, Annette Aigner, Jan Felix Drexler

“…Socioeconomic variables showed similar patterns for both the established measles–mumps–rubella and the new COVID-19 vaccines. …”
Get full text

Relationship between pharmacotherapy for major depressive disorder and healthcare utilisation in British Columbia, Canada: a retrospective population-based cohort by Sonya Cressman, Louisa Edwards, Kimberlyn McGrail, Stirling Bryan, Alison Hoens, Rohit Vijh, Sandra Peterson, Zeina Waheed, Mary Bunka, Nick Pang, Shahzad Ghanbarian, Gavin Wong, Linda Riches, Jehannine Austin

“…Objectives To describe the population that meets the criteria for major depressive disorder (MDD) in British Columbia (BC), compare patterns of healthcare utilisation between those with MDD who are and are not prescribed pharmacotherapy, and assess these relationships in models that control for potential confounding variables.Design We used a population cross-sectional study design among a cohort of individuals living with MDD and examined the relationship between pharmacotherapy and healthcare utilisation between 2019 and 2020 using linked billing and administrative data.Setting This study identified individuals with MDD using a validated case definition of International Classification of Diseases (ICD) codes in BC, Canada.Participants The final study cohort included 549 029 adult participants who met the MDD case definition.Explanatory variable Explanatory variable was the use of prescription antidepressant medication during the study period, based on BC PharmaNet data.Covariates Covariates include sociodemographic characteristics (age, sex, urban/rural residence, neighbourhood income quintile and comorbidities).Primary outcome measure Primary outcome measure was healthcare utilisation (outpatient physician visits, emergency department (ED) visits and hospitalisations).Results We stratified our analysis based on whether study participants were classified as ‘recently incident’ or ‘actively prevalent’. …”
Get full text

Genome-wide identification and gene expression analysis of the malate dehydrogenase (MDH) gene family in Eucalyptus grandis by Yifan Xing, Yifan Xing, Huiming Xu, Deming Yang, Lichuan Deng, Guolong Li, Guolong Li, Zhixin Zhao, Zhixin Zhao, Zhaohua Lu, Liuyin Ma, Guangyou Li

“…EgMDHs showed tissue- and stage-dependent expression, particularly during late adventitious root development. EgMDH genes also exhibited temporally distinct expression patterns under JA treatment, SA treatment, salt stress and cold stress conditions. …”
Get full text

Advances in soil salinity diagnosis for mangrove swamp rice production in Guinea Bissau, West Africa by Gabriel Garbanzo, Jesus Céspedes, Marina Temudo, Maria do Rosário Cameira, Paula Paredes, Tiago Ramos

“…Mangrove swamp cultivation is the most productive rice system in this area but is highly vulnerable to changes in rainfall patterns due to soil salinity. Diagnosing and identifying areas of high salinity concentration are essential strategies for adapting to climate change and mitigating its impacts. …”
Get full text

Tryptophan metabolic reprogramming modulates cytokine networks in nucleos(t)ide analogue-treated chronic hepatitis B patients by Xuedan Gao, Xuedan Gao, Xuedan Gao, Xiaojuan Wu, Xiaojuan Wu, Xiaojuan Wu, Yi Li, Yi Li, Yi Li, Xinhua Dai, Xinhua Dai, Xinhua Dai, Bei Cai, Bei Cai, Bei Cai

“…Multivariate analyses were performed.ResultsFunctional cure patients showed unique metabolic patterns. Indole-3-carboxaldehyde (IAld) levels increased progressively from HBsAg positive groups (HBeAg-: 63.324 nmol/L; HBeAg+: 65.938 nmol/L) to functional cure (91.44 nmol/L) and healthy controls (130.634 nmol/L) (P < 0.01), exhibiting negative correlations with HBsAg (r = -0.31) and IFN-γ (r = -0.53) but positive correlation with IL-1β (r = 0.47). …”
Get full text

Breastfeeding trajectory of mothers of preterm infants within 6 months postpartum: A longitudinal study by Na Wu, Yijing Wang, Lijing Ding, Yiting Xu, Xuyan Jia, Keying Huo, Xiao Yao, Wenyan Zhang, Yue Wan, Peimin Xie, Lin Ye, Rong Huang

“…Household income, spouse's educational background, smoking in the spouse, breastfeeding patterns before discharge (T0), perceived breastfeeding control and breastfeeding intention (T1), perceived breastfeeding control, breastfeeding intention, and breastfeeding knowledge (T2), and perceived breastfeeding control, breastfeeding positive attitude, and breastfeeding negative attitude (T3) were predictors of different profiles. …”
Get full text

Clinical features and antibiotic resistance in pediatric pneumococcal meningitis in Southern Vietnam, 2012–2023: A multicenter retrospective study by Hieu Cong Truong, Thanh Van Phan, Hung Thanh Nguyen, Thang Vinh Ho, Dai Thi Trang Vo, Thuong Vu Nguyen, Trung Vu Nguyen, Niko Speybroeck

“…This study investigates the clinical features, cerebrospinal fluid (CSF) findings, serotype distribution, and antibiotic resistance patterns in Vietnamese children aged 1–59 months with pneumococcal meningitis (PM). …”
Get full text

Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids by Paloma Navarro, Tatiana P. Grazioso, Arantzazu Barquín, Maria Barba, Mónica Yagüe, Carlos Millán, Irene López, Elena Sevillano, Miguel Quiralte, Paloma Fernández, Diego Losada, Eduardo Caleiras, Julia Calzas, Beatriz Jiménez, Sergio Ruiz-Llorente, Juan Justo, Félix Guerrero, Vital Hevia, Raquel Martín, Francisco José Pérez-Rodriguez, Julia Tejerina, Mario Prieto, Paula Comune, Juan Francisco Rodriguez-Moreno, Jesús García-Donás

“…PDOs reproduced pathological and immunohistochemical patterns of source tumors, with pathogenic variants confirmed in 84% (21/25). …”
Get full text

Comprehensive analysis across SMN2 excludes DNA methylation as an epigenetic biomarker for spinal muscular atrophy by Maria M. Zwartkruis, Joris V. Kortooms, Demi Gommers, Martin G. Elferink, Ilaria Signoria, Joyce van der Sel, Paul J. Hop, Ramona A.J. Zwamborn, Robin Geene, Jared W. Green, Hanneke W.M. van Deutekom, Wouter van Rheenen, Jan H. Veldink, Fay-Lynn Asselman, Renske I. Wadman, W. Ludo van der Pol, Gijs W. van Haaften, Ewout J.N. Groen

“…Using native, long-read nanopore and targeted short-read bisulfite sequencing, we analyzed methylation patterns across the 30 kb SMN2 gene. Our long-read analysis of 29 SMA patients identified tissue-specific variation in SMN2 intronic regions and the 3′UTR. …”
Get full text

Early childhood education and care quality and associations with child outcomes: A meta-analysis. by Antje von Suchodoletz, D Susie Lee, Junita Henry, Supriya Tamang, Bharathy Premachandra, Hirokazu Yoshikawa

“…Together, the results might have been biased towards patterns prevalent in the U.S. that might not apply to other, non-U.S. …”
Get full text

Evaluating the performance of herd-specific long short-term memory models to identify automated health alerts associated with a ketosis diagnosis in early-lactation cows by N. Taechachokevivat, B. Kou, T. Zhang, M.E. Montes, J.P. Boerman, J.S. Doucette, R.C. Neves

“…Long short-term memory (LSTM) models are machine learning models capable of learning temporal patterns and making predictions based on time series data. …”
Get full text

The Relationship Between Protein Fraction Contents and Immune Cells in Milk by Haitong Wang, Xiaoli Ren, Li Liu, Zhuo Yang, Chunfang Li, Xiangnan Bao, Ayihumaer Amantuer, Peipei Wen, Dongwei Wang, Shujun Zhang

“…Four linear mixed models were applied to analyze the secretion patterns of milk protein fractions by days in milk (DIM) and parity, their variations under different mastitis conditions, and their associations with the somatic cell score (SCS), DSCC, and immune cell counts (PMN + LYM score (PMN + LYMS) and MAC score (MACS)). …”
Get full text

The Consumption of Beeswax Alcohol (BWA, Raydel^®) Improved Zebrafish Motion and Swimming Endurance by Protecting the Brain and Liver from Oxidative Stress Induced by 24... by Kyung-Hyun Cho, Yunki Lee, Ashutosh Bahuguna, Sang Hyuk Lee, Chae-Eun Yang, Ji-Eun Kim, Hyo-Shin Kwon

“…The HC+Gal-induced cognitive changes, marked by staggered and confused swimming behavior, and retarded swimming speed and motion patterns (restricted to the bottom of the tank), were efficiently restored by BWA. …”
Get full text

The Role of Values and Emotions in Accepting Fake Political News in the Post-Truth Era by Amir Mollaee Mozaffari, Ali Ashraf Nazari

“…The interview data were analyzed using Discursive Psychology, focusing on the linguistic patterns and discourse structures in the participants' responses. …”
Get full text

DIDACTIC POTENTIAL OF YOUTUBE CHANNELS FOR ENHANCED ENGLISH LANGUAGE LEARNING IN NON-LINGUISTIC PROGRAMS by Blynova Neliia, Medynska Svitlana, Voloboieva Anna

“…Strategically chosen YouTube vlogs can significantly enhance students’ vocabulary development, facilitate the acquisition of idioms and colloquial speech patterns, improve pronunciation, strengthen linguistic competencies, and refine listening and speaking skills. …”
Get full text