Intrahepatic cholangiocarcinoma trends and treatment lines: real-world evidence from the French National Hospital Discharge database by M. Delaye, B. Grenier, A. Lièvre, C. Neuzillet

“…Background: Little is known about the therapeutic trajectory of patients treated in hospitals for intrahepatic cholangiocarcinoma (iCCA) and patterns of care in daily clinical practice. Patients and methods: An observational retrospective study was conducted on the French National Hospital Discharge Database. …”
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Plant phenotyping and root‐associated metabolomics reveal insights into pathogen protection by diverse arbuscular mycorrhizal fungi by Natascha V. Weinberger, Ximena Cibils‐Stewart, Chris Brien, Nathaniel Jewell, Bettina Berger, Timothy R. Cavagnaro, Matthias J. Salomon, Meena Mikhael, Jonathan M. Plett, Krista L. Plett, Jeff R. Powell

“…Our results show that most AM fungal isolates enhanced plant growth, with two out of four demonstrating MIR‐effective potential during symbiosis with tomatoes without trade‐offs. …”
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Evaluation of Multidrug Resistance of <i>Salmonella</i> Isolated from Pork Meat Obtained from Traditional Slaughter Systems in Romania by Alexandra Tăbăran, Sorin Danel Dan, Liora Mihaela Colobaţiu, Marian Mihaiu, Sergiu Condor, Rodica Mărgăoan, Oana Lucia Crişan-Reget

“…This study investigates the prevalence and antibiotic resistance patterns of <i>Salmonella</i> serovars isolated from traditionally sourced pork meat in Romania. …”
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Women’s Empowerment and Gender-Related Factors Associated with Maternal Tetanus Protection in 39 Low- and Middle-Income Countries by Katherine Kirkby, Luisa Arroyave, Franciele Hellwig, M. Carolina Danovaro-Holliday, Nasir Yusuf, Shirin Heidari, Stephanie Shendale, Aluísio J. D. Barros, Ahmad Reza Hosseinpoor

“…<b>Background:</b> Tetanus is a vaccine-preventable disease, and therefore vaccination of women of reproductive age or during pregnancy is recommended alongside childhood tetanus vaccination. …”
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Altered Feeding Behaviors and Adiposity Precede Observable Weight Gain in Young Rats Submitted to a Short-Term High-Fat Diet by David E. Andrich, Lilya Melbouci, Ya Ou, Jean-Philippe Leduc-Gaudet, François Chabot, François Lalonde, Fábio Santos Lira, Bruce D. Gaylinn, Gilles Gouspillou, Gawiyou Danialou, Alain-Steve Comtois, David H. St-Pierre

“…Information regarding the early effects of obesogenic diets on feeding patterns and behaviors is limited. To improve knowledge regarding the etiology of obesity, young male Wistar rats were submitted to high-fat (HFD) or regular chow diets (RCDs) for 14 days. …”
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Integrative analysis of gene expression and chromatin dynamics multi-omics data in mouse models of bleomycin-induced lung fibrosis by Zhongzheng Li, Mengke Zhang, Yujie Zhang, Yulong Gan, Zhao Zhu, Jiawei Wang, Yanlin Zhou, Guoying Yu, Lan Wang

“…Methods Utilizing a bleomycin-induced pulmonary fibrosis model, we conducted a comprehensive analysis of the interplay between chromatin structure, chromatin accessibility, gene expression patterns, and cellular heterogeneity. Our chromatin structure analysis included 5 samples (2 control and 3 bleomycin-treated), while accessibility and expression analysis included 6 samples each (3 control and 3 bleomycin-treated). …”
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Metabolomic Profiling of <i>BPH14/BPH15</i> Pyramiding Rice and Its Implications for Brown Planthopper Resistance by Liang Hu, Dabing Yang, Hongbo Wang, Xueshu Du, Yan Wu, Liang Lv, Tongmin Mou, Aiqing You, Jinbo Li

“…Differentially accumulated metabolites (DAMs) displayed different patterns in B1415 and RP, particularly in flavonoid and phenylpropanoid biosynthesis pathways, which were more pronounced in the resistant B1415. …”
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Spatiotemporal characteristics and mechanisms of upper water exchange between the Arabian Sea and the Bay of Bengal in the North Indian Ocean by Defu Zheng, Defu Zheng, Defu Zheng, Junru Guo, Junru Guo, Junru Guo, Yanzhao Fu, Yanzhao Fu, Yanzhao Fu, Yanzhao Fu, Jun Song, Jun Song, Jun Song, Jun Song, Jun Song, Yu Cai, Yu Cai, Yu Cai

“…These findings highlight the effectiveness of the spectral clustering method in revealing the spatiotemporal patterns of water masses, which is important for understanding the ocean circulation system and associated climate variability in the North Indian Ocean.…”
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Antibody Preparation, Protein Expression, and Function Analysis of Cyp19a1b in Ovarian Differentiation in a Natural Triploid Teleost Qi River Crucian Carp (<i>Carassius auratus</i>... by Yongjing Li, Yujiao Jin, Limin Wu, Xuejun Li

“…Western blotting results showed that Cyp19a1b was mainly expressed in the brain and then in the ovary, heart, liver, and muscle. During embryogenesis, Cyp19a1b was abundantly expressed in the neurula stage. …”
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Stiffness characteristics of the lower extremities in Women’s Chinese Basketball Association competition athletes: normative values and position differences by Dan Wang, Zhihai Wang, Mingming Yang, Kaiyuan Qu, Xinyu Mao, Xin Yang, Zhiye Zhang, Che Shao, Eamonn Delahunt, Eamonn Delahunt, Wenxuan Fang

“…Stiffness was evaluated before and during the 2020–2021 WCBA season, which was averaged for data analysis. …”
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Molecular cloning of TPM3 gene in qinchuan cattle and its effect on myoblast proliferation and differentiation by Juntao Guo, Jianfang Wang, Ke Zhang, Zhimei Yang, Bingzhi Li, Yueting Pan, Hengwei Yu, Shengchen Yu, Sayed Haidar Abbas Raza, Belete Kuraz Abebea, Linsen Zan

“…Notably, a noticeable increase in TPM3 expression was observed in the longissimus dorsi muscle and myocardium of calves and adult cattle. Expression patterns varied during different stages of myoblast differentiation. …”
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Targeted treatment and survival in advanced non-squamous non-small cell lung cancer patients – a nationwide and longitudinal study by Johanne Elise Nyen, Anja Ødegård Booth, Øyvind Husby, Christoffer Bugge, Ingrid Engebretsen, Francisco Oteiza, Åslaug Helland, Åslaug Helland, Lars Fjellbirkeland, Lars Fjellbirkeland, Odd Terje Brustugun, Odd Terje Brustugun, Bjørn Henning Grønberg, Bjørn Henning Grønberg

“…However, patients eligible for targeted therapy still had a survival improvement during the study period.…”
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Coronal plane alignment of knee (CPAK) classification in Indians undergoing total knee arthroplasty: Are there racial differences in phenotype distribution? by Akshay Ks, Pathik Shah, Rahul Ragate, Aashiket Sable, Vaibhav Bagaria

“…Introduction: Optimizing alignment &amp; balance strategies during Total Knee Arthroplasty (TKA) requires a comprehensive understanding of lower limb constitutional alignment. …”
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Evaluation of a national supermarket intervention supporting vulnerable families in healthy meal practices: a natural experiment by Marjolijn Vos, Viktor L. J. Proesmans, Anneleen Van Kerckhove, Benedicte Deforche, Nathalie Michels, Maartje P. Poelman, Wendy Van Lippevelde

“…Conclusions The DS123 intervention improved food purchasing patterns in families with lower SES, increasing spending on vegetables while reducing spending on prepackaged meals and snacks. …”
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Interaction between post-tumor inflammation and vascular smooth muscle cell dysfunction in sepsis-induced cardiomyopathy by Rui Liu, Lina Jia, Lin Yu, Detian Lai, Qingzhu Li, Bingyu Zhang, Enwei Guo, Kailiang Xu, Qiancheng Luo

“…The DVL1 gene module related to SIC was identified by means of WGCNA, and the immune infiltration analysis demonstrated the distinctive immune cell patterns associated with DVL1 expression and the impact of DVL1 on immunotherapeutic resistance.ConclusionsDVL1 is a core regulator of SIC and other cancers and, therefore, can serve as a therapeutic target. …”
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At-Home Stroke Neurorehabilitation: Early Findings with the NeuroExo BCI System by Juan José González-España, Lianne Sánchez-Rodríguez, Maxine Annel Pacheco-Ramírez, Jeff Feng, Kathryn Nedley, Shuo-Hsiu Chang, Gerard E. Francisco, Jose L. Contreras-Vidal

“…Furthermore, linear mixed-effects statistical models showed a significant reduction in trial duration (<i>p</i>-value < 0.02) and concomitant changes in brain patterns (<i>p</i>-value < 0.02). Conclusions: the analysis of these findings suggests that a low-cost, safe, simple-to-use BMI system for at-home stroke rehabilitation is feasible.…”
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Meteorological determinants of hepatitis E dynamics in Jiangsu Province, China: a pre-COVID-19 era study focusing on multi-route transmission (2005–2018) by Peihua Li, Jia Rui, Kangguo Li, Deng Bin, Hongjie Wei, Xi Tan, Tianmu Chen

“…Analysis of four dependent variables (incidence, β, βw and βp′) revealed distinct climate-driven patterns: (1) Incidence exhibited dual seasonal peaks linked to atmospheric pressure, sunshine duration, and humidity; (2) Host-to-person transmission (βp′) was most sensitive to climatic conditions, peaking at 1013 hPa and declining sharply above 75% humidity, while susceptible person-to-infected person (β) and environment-to-person (βw) transmission were primarily modulated by humidity and wind speed; (3) The GAM validation confirmed robust performance for transmission coefficients (p &lt; 0.001). …”
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Adaptive Responses of Large Yellow Croaker <i>Larimichthys crocea</i> to Ocean Acidification: Integrative Analysis of Gill and Kidney Transcriptomics and Antioxidant Enzyme Activit... by Ting Ye, Xiaoyan Zhang, Feng Liu, Xiao Liang, Dandan Guo, Bao Lou, Zhigang Xie

“…Transcriptomic analysis revealed distinct gene expression patterns between the gills and kidneys under acidification stress. …”
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Semi-automated three-dimensional reconstruction of cervical paravertebral muscles based on CT images to explore the relationship between cervical flexors and extensors and cervical... by Yuelin Cheng, Xinyan Zhao, Zehua Jiang, Mengmeng Zhou, Hao Yu, Linyan Liu, Xuanhao Fu, Rusen Zhu

“…In this research, semi - automatic three - dimensional reconstruction of PSM in CSM patients was carried out via CT, and the changing patterns of PSM and its relationship with cervical lordosis were explored. …”
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Characteristics of temporal changes and influencing factors of carbon dioxide and methane fluxes at the water-gas interface of the Inner Mongolia section of the Yellow River by Aruhan, Xia Wu, Wuyinga, Hongxia Bao, Yue Lang, Narentuya, Fang Liu, Liming Qi, Xiaoli Wang

“…Due to the fact that emission patterns and driving mechanisms of riverine CO2 and CH4 differ across time scales, it is necessary to conduct more precise observations with high spatial and temporal resolution in order to acquire the most reliable data and comprehend more targeted approaches to carbon emission reduction.…”
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