CD spectra reveal the state of G-quadruplexes and i-motifs in repeated and other DNA sequences by Levi Diggins, Daniel Ross, Sundeep Bhanot, Rebecca Corallo, Rachel Daley, Krishna Patel, Olivia Lewis, Shane Donahue, Jacob Thaddeus, Lauren Hiers, Christopher Syed, David Eagerton, Bidyut K. Mohanty

“…The SSB disassembled both G4s and iMs formed by almost all sequences suggesting an in vivo role for SSBs in the disassembly of G4s and iMs during DNA replication and other DNA transactions.…”
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Deciphering the molecular signatures of tropical Areca catechu L. under cold stress: an integrated physiological and transcriptomic analysis by Han Li, Linbi Zhang, Xinyu Wen, Changlei Ji, Hui Chen, Meng Tian, Fusun Yang, Jun He, Jun He

“…The findings of this study delineate three key aspects: (1) temporal dynamics of cold-responsive physiological processes, (2) pathway-level characterization of DEG enrichment patterns, and (3) genetic determinants underlying cold stress adaptation.DiscussionThese findings clarify the time series and core physiological indicators of A. catechu during various physiological processes, identify pivotal genes associated with cold stress, and provide a gene-to-phenotype framework for optimizing cold-resilient cultivation protocols and molecular marker-assisted breeding strategies.…”
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Tracking the infection dynamics of Fusarium oxysporum in Codonopsis pilosula based on GFP labelling by Mingming Shi, Huixia Li, Wei Guo, Ning Luo, Jinghuan Chen, Yonggang Liu, Rui Liu, Zhenchuan Mao

“…Wound inoculation at the rhizome accelerated infection, consistent with field disease patterns linked to soil microfauna-induced injuries.DiscussionThis study provides a robust platform for investigating F. oxysporum pathogenicity in C. pilosula and offers guidance on protective measures to maintain rhizome integrity during cultivation.…”
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APOLLO-Live: A multi-criteria-based webtool for synchronous group decision making and consensus support in energy and climate policy deliberations [version 3; peer review: 1 approv... by Anastasios Soursos, Konstantinos Koasidis, Álvaro Labella, Georgios Xexakis, Alexandros Nikas, Anastasios Karamaneas

“…It also fleshes out differences in the voting patterns of different groups of voters and calculates a consensus metric to shed light on conflicts arising. …”
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Genome wide identification and characterization of Bax inhibitor-1 gene family in cucumber (Cucumis sativus) under biotic and abiotic stress by Samia Anwar, Riffat Siddique, Shakeel Ahmad, Muhammad Zeshan Haider, Haider Ali, Adnan Sami, Rosa Sanchez Lucas, Muhammad Shafiq, Bader Un Nisa, Bilal Javed, Jannat Akram, Javaria Tabassum, Muhammad Arshad Javed

“…The CsBI3, CsBI4 and CsBI5 genes exhibit elevated expression levels during cold stress, suggesting their vital involvement in cucumber plant defense mechanisms. …”
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South East Asian Nutrition Surveys (SEANUTS) II – a multi-country evaluation of nutrition and lifestyle indicators in children aged 12 years and below: rationale and design by Serene Yaling Tan, Bee Koon Poh, Rini Sekartini, Nipa Rojroongwasinkul, Thuy Nga Tran, Jyh Eiin Wong, Dian Novita Chandra, Tippawan Pongcharoen, Khanh Van Tran, Lucas Actis-Goretta, Marlotte M Vonk, Swee Ai Ng, Panam Parikh, Ilse Khouw, SEANUTS II Study Group

“…With the pandemic emerging during the study, a COVID-19 questionnaire was developed and implemented. …”
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Multimorbidity incidence following hospitalization for SARS-CoV-1 infection or influenza over two decades: a territory-wide retrospective cohort study by Cuiling Wei, Chor Wing Sing, Eric Yuk Fai Wan, Ching Lung Cheung, Ian Chi Kei Wong, Francisco Tsz Tsun Lai

“…Notable differences in the patterns of multimorbidity were identified between the two arms. …”
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Heat Waves and Early Birth: Exploring Vulnerability by Individual‐ and Area‐Level Factors by A. Fitch, M. Huang, M. J. Strickland, A. J. Newman, C. Kalb, J. L. Warren, S. Kelley, X. Zheng, H. H. Chang, L. A. Darrow

“…Heat‐related early term birth risk is enhanced among subgroups associated with socioeconomic disadvantage, but patterns of vulnerability were less consistent for preterm birth.…”
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Geospatial Solutions for Urban Climate Adaptation: The LCZ-UHI-GEO Project between Italy and Vietnam by M. Žgela, A. Vavassori, M. A. Brovelli, G. Venuti, D. Tapete, P. Sacco, P. T. M. Thy, L. D. Nguyen

“…The resulting high-resolution temperature maps revealed distinctive UHI patterns for each period, with peak intensity observed during night-time. …”
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Physical restraint use in children with mental and behavioral health emergencies in the prehospital setting by Ashley A. Foster, Kenshata Watkins, Tarak K. Trivedi, Marisol Cruz‐Romero, Sara A. Leibovich, Rajesh K. Daftary, Aaron E. Kornblith, Jacqueline Grupp‐Phelan, Karl A. Sporer, Colleen Kellison, Nicolaus W. Glomb

“…Descriptive statistics were used to characterize the primary outcome and associated demographic and diagnostic features, as well as temporal use patterns. Sex and age were compared between restrained and non‐restrained youth using chi‐square analysis. …”
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Characterization and prognostic of CD8 + TIM3 + CD101 + T cells in glioblastoma multiforme by Hong-Liang Wang, Sai Li, Chun-Chun Ma, Xiang-Hu Zheng, Hao-Yuan Wu, Chen-Xi Chang, Zhi-Hao Yang, Jia-Wei Wang, Fa-Ming Pan, Bing Zhao

“…Pseudotime analysis indicated CD8 + TIM3 + CD101-T cells as precursors to CCT cells, unveiling unique gene expression patterns during this transition. The prognostic model, incorporating 22 gene features via LASSO regression, demonstrated strong predictive ability through Receiver Operating Characteristic (ROC) curves. …”
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Multi-Scenario Simulating the Effects of Land Use Change on Ecosystem Health for Rural Ecological Management in the Zheng–Bian–Luo Rural Area, Central China by Hejie Wei, Qing Han, Yu Ma, Wenfeng Ji, Weiguo Fan, Mengxue Liu, Junchang Huang, Ling Li

“…Using the “Ecosystem Vigor-Organization-Resilience-Services” model, the study evaluates the spatiotemporal patterns of ecosystem health. The Patch-generating Land Use Simulation (PLUS) model was employed to simulate land use and ecosystem health in 2035 under three scenarios: Natural Development (ND), Ecological Protection (EP), and Cropland Protection (CP). …”
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Exploration of the impact of air pollutants on the influenza epidemic after the emergence of COVID-19: based on Jiangsu Province, China (2020–2024) by Chengxi Zheng, Xin Jiang, Yi Yin, Qigang Dai, Shuhan Tang, Jianli Hu, Changjun Bao, Haitao Yang, Zhihang Peng, Zhihang Peng, Zhihang Peng

“…BackgroundNon-pharmaceutical interventions (NPIs) during the COVID-19 pandemic altered influenza transmission patterns, yet the age-specific effects of air pollutants on influenza dynamics remain unclear.MethodsUtilizing influenza surveillance data of Jiangsu Province from 2020 to 2024, we integrated generalized additive quasi-Poisson regression model and distributed lag non-linear models (DLNM) to quantify lagged effects and exposure-response relationships between air pollutants (NO2, SO2, PM2.5) and influenza risk across young, middle-aged, and older adult groups. …”
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Efficacy and safety of a biosimilar laronidase versus the reference laronidase in patients with mucopolysaccharidosis type I by Ali Rabbani, Mohammadreza Alaei, Samaneh Norouzi Asl, Aria Setoodeh, Marjan Shakiba, Shadab Salehpour, Peyman Eshraghi, Omid Salehpour, Araz Sabzvari, Hamidreza Kafi, Ali Jarollahi

“…Post-infusion enzyme activity levels showed similar patterns between Aldurazyme and Laronidase (CinnaGen), with no detectable activity before the infusion. …”
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Hybrid Graph Representation and Learning Framework for High-Level Synthesis Design Space Exploration by Pouya Taghipour, Eric Granger, Yves Blaquiere

“…Indeed, modeling HLS-related problems using GNNs that efficiently capture the complex patterns arising from applied pragmas and low-level characteristics of HLS specifications is challenging. …”
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Early dynamic changes in platelet counts and 28-day mortality in sepsis patients: a retrospective cohort study using dynamic latent class model and generalized additive mixture mod... by Yong Han, Yong Han, Jie Liu, Zhenhua Huang, Zhenhua Huang, Haofei Hu, Haiyan Yin

“…A dynamic latent class model analyzed the patterns of PLT count changes during the first week of hospitalization. …”
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Insights into Conjugate Hemispheric Ionospheric Disturbances Associated with the Beirut Port Explosion on 4 August 2020 Using Multi Low-Earth-Orbit Satellites by Adel Fathy, Yuichi Otsuka, Essam Ghamry, Dedalo Marchetti, Rezy Pradipta, Ahmed I. Saad Farid, Mohamed Freeshah

“…In this study, we analysed remote sensing data collected during the Beirut port explosion on 4 August 2020 at 15.08 UT. …”
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Clinical innovation research model for fundus diseases: 6 elements, 3 ones by WEN Feng, ZHANG Xiongze, LI Miaoling, GAN Yuhong, SU Yongyue

“…The "3 Ones"pathway embodies hierarchical research progression - transitioning from individual phenomena (point observations) to population-level patterns (linear correlations), ultimately constructing a multidimensional disease cognition network(planar integration). …”
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Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa) by Mengmeng Shi, Yike Wang, Peng Lv, Yujie Gong, Qi Sha, Xinyan Zhao, Wen Zhou, Lingtao Meng, Zegang Han, Lingxiao Zhang, Lingxiao Zhang, Yongwang Sun, Yongwang Sun

“…Gene expression profiles analyzed by RT-qPCR experiments demonstrated that MsADF genes exhibited distinct expression patterns among different organs. Furthermore, the majority of MsADF genes were induced by salt and drought stress by more than two-fold, with MsADF1, 2/3, 6, and 9 being highly induced, suggesting their critical role in resistance to abiotic stress. …”
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Population Structure Dynamics of Elasmobranchs Susceptible to Shrimp Trawling Along the Southern Gulf of Mexico by Heber Zea-de la Cruz, César Meiners-Mandujano, Javier Tovar-Ávila, Lourdes Jiménez-Badillo, Jorge Luis Oviedo-Pérez

“…These species were caught in a range of sizes, from newborns to mature individuals, and showed both inter- and intraspecific segregation patterns across fishing zones, seasons, and depths. …”
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