<i>SHROOM3</i> Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization by Li-Nan Xu, Ying-Ying Sun, Yan-Feng Tan, Xin-Yue Zhou, Tian-Chao Xiang, Ye Fang, Fei Li, Qian Shen, Hong Xu, Jia Rao

“…Here, we analyzed single-cell transcriptomic datasets and the Nephroseq database to delineate <i>SHROOM3</i> expression patterns in proteinuric kidney diseases. Using podocyte-specific <i>SHROOM3</i> knockout mice and an Adriamycin (ADR)-induced nephropathy mouse model, we demonstrated that glomerular <i>SHROOM3</i>, specifically in podocytes, was upregulated following ADR treatment during the acute injury phase but downregulated in chronic kidney disease. …”
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Genomic complexity and clinical significance of the RCCX locus by Vladimir V. Shiryagin, Andrey A. Devyatkin, Oleg D. Fateev, Ekaterina S. Petriaikina, Viktor P. Bogdanov, Zoia G. Antysheva, Pavel Yu Volchkov, Sergey M. Yudin, Mary Woroncow, Veronika I. Skvortsova

“…Nearly identical, repetitive elements in the genome contribute to the variability in genetic inheritance patterns, particularly in regions like the RCCX locus, where such repeats can lead to structural variations. …”
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Modeling the Impact of Public Transportation and Mitigation Strategies in COVID-19 Spread in Mexico City by Fernando Reyes-Gomez, Emmanuel Torres-Marin, Maria Elena Larraga, Luis Alvarez-Icaza, Roman A. Mora-Gutierrez

“…Furthermore, the model incorporates several key time-varying parameters such as district population, commuting patterns, and contact matrices for different settings. …”
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Co-drivers of air pollutant and CO2 emissions in China from 2000 to 2020 by Wenxin Cao, Yixuan Zheng, Shaohui Zhang, Zbigniew Klimont, Xian’en Wang, Fangming Jiang, Zhulin Qi, Chuchu Chen, Yueyi Feng, Zechen Zhang, Hongkuan Zang, Yu Lei, Gang Yan

“…Here, we develop an integrated analytical framework combining a detailed sectoral emission inventory, index decomposition analysis, and a clustering algorithm to investigate China’s synergetic patterns of air pollutant and CO2 emissions across 15 socioeconomic sectors from 2000 to 2020 and uncover the co-drivers behind these trends, with detailed temporal, sectoral, and spatial dynamics revealed. …”
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Genome-wide identification and characterization of the Brassinazole-resistant gene family and associated responses to osmotic stress in Avena sativa by Shirui Xu, Shirui Xu, Shirui Xu, Zihao Wei, Zihao Wei, Mingchuan Ma, Mingchuan Ma, Mingchuan Ma, Lijun Zhang, Lijun Zhang, Lijun Zhang, Zhang Liu, Zhang Liu, Zhang Liu, Longlong Liu, Longlong Liu, Longlong Liu, Longlong Liu

“…Examination of gene duplication revealed that segmental duplications drove the expansion of the BZR gene family in the oat genome, with evidence of strong purifying selection pressure during evolutionary development. The qRT-PCR analysis demonstrated varied expression patterns among AsBZR members. …”
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Single Cell and Transcriptomic Analysis of Regulatory Mechanisms of Key Genes in Systemic Lupus Erythematosus by Zhou Y, Wu Y, Yang B, Zhu Q, Long H, Yuan L, Cao W, Deng D

“…Methylation analysis showed distinct gene regulation patterns, and pseudotime analysis demonstrated dynamic expression of IFI44L and MX1 during B cell differentiation.Conclusion: This study integrated single-cell and bulk transcriptomic data to identify six key genes (MX1, IFI44L, ISG15, OAS1, IFI6, and IFI27) involved in SLE pathogenesis and highlighted the central role of memory B cells. …”
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Challenging assumptions: a tripartite assessment of medical quality, resource utilization, and equity concerns in pediatric telemedicine by Motti Haimi, Ruslan Sergienko, Tzipi Hornik-Lurie, Dov Albukrek

“…Objective This study evaluated pediatric telemedicine services across three dimensions: clinical outcomes (antibiotic prescribing patterns), resource utilization implications (healthcare utilization and emergency department visits), and equity considerations (sociodemographic distribution of services). …”
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Phosphorus transitions driven by cyclone biparjoy linked middle east North Africa (MENA) and Indian Thar Desert dust storm pathways in Asia’s largest grassland by Rupak Dey, Seema B. Sharma, Mahesh G. Thakkar, Ranjit Kumar Sarangi, Abhiroop Chowdhury, Aliya Naz

“…Our findings revealed that the Middle East, North Africa, and Thar Desert significantly contributed to phosphorus deposition in the target grassland during specific seasons. The SW cyclone ‘Biparjoy’, which followed the same track of aerosol loading (MENA), made landfall in this zone (June 16, 2023) and affected the P depositional patterns. …”
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Alpine Adaptive Mechanism on Rhizosphere Microbes Recruitment of <i>Crepis napifera</i> (Franch.) Babc. by Multi-Omics Analysis by Genlin Yang, Weiwei Liu, Xinchun Mo, Zhinan Mei

“…<b>Methods:</b> Transcriptome sequencing, metabolomic profiling, and 16S rRNA gene amplicon sequencing were employed to assess the transcriptional expression patterns, metabolic variations, and rhizosphere microbial community composition of <i>C. napifera</i> (Franch.) …”
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Upper Limb Neural Tension Test and Spinal Biomechanics: Insights from a Longitudinal Pilot Study by Massimo Rossi, Marianna Signorini, Ali Baram, Mario De Robertis, Gabriele Capo, Marco Riva, Maurizio Fornari, Federico Pessina, Carlo Brembilla

“…The developed motion capture analysis method offers a novel approach to quantify fine spinal motion patterns.…”
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COVID-19’s effect on healthcare disparities: delivery, reimbursement, and premature mortality in residentially segregated populations by Kasabji Feras, Kasabji Feras, Ferenc Vincze, Kinga Lakatos, Kinga Lakatos, Anita Pálinkás, László Kőrösi, László Ulicska, Karolina Kósa, János Sándor, János Sándor

“…This paper evaluates the impact of COVID-19 on healthcare delivery and reimbursement disparities in Hungary, particularly focusing on segregated populations.AimsTo examine healthcare utilization and reimbursement patterns among patients in segregated areas (SA) and non-segregated or complementary areas (CA) during the first year of the COVID-19 pandemic, compared to pre-pandemic levels, and to understand how these patterns influenced overall health outcomes.MethodsA cross-sectional study using 2019 and 2020 healthcare data from all Hungarian general medical practices (GMPs) was conducted. …”
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Comparative In vitro antibacterial activity of nemonoxacin and other fluoroquinolones in correlation with resistant mechanisms in contemporary methicillin-resistant Staphylococcus... by Pao -Yu Chen, Mao-Wang Ho, Po-Liang Lu, Hung-Jen Tang, Cheng Len Sy, Jann-Tay Wang, Taiwan Staphylococcus aureus Consortium (TSAC)

“…Compared to other AAS patterns, isolates in group A had the greatest non-susceptible proportions to nemonoxacin (86.9%; overall/pair-wised comparisons, P < 0.05). …”
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Physical simulation experiment on horizontal docking well leaching for salt cavern storage by Jianfu WANG, Zuoliang JIN, Jianguang LI, Jianchao JIA, Kuoyuan ZHU, Zhaoheng ZHOU

“…To effectively guide the field application of this method, research into the influence patterns of dissolution inhibitor cushions on the cavern shapes resulting from docking well leaching and brine concentrations is necessary. …”
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Virome profiling of Aedes albopictus across urban ecosystems in Guangdong reveals sex-specific diversity by Qianlin Li, Jicheng Huang, Yanrong Zhou, Qin Wu, Jian Zhou, Fengxia He, Lirun He, Yongxia Shi, Cheng Guo, Jun Dai

“…Results A comparative analysis of virome profiles in male and female Aedes albopictus across five regions of Guangdong Province (Chaozhou, Guangzhou, Shaoguan, Shenzhen, Zhanjiang) revealed significant viral distribution patterns influenced by both sex and geographic location. …”
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Monazite U-Pb age, geochemistry, and genesis of ore-bearing granites in the Zhukeng tungsten deposit, southern Jiangxi Province by GAO Yuan, WANG Ying, WANG Hai, XU Zhe, ZHANG Yong, ZHOU Yu, ZHANG Fangrong, SUN Chao, HE Bin, ZHANG Siyuan, ZHANG Fushen

“…Total rare earth elements (ΣREE) range from 106.86×10−6 to 124.24×10−6, and there are right-dipping light rare earth enrichment patterns with a significant negative Eu anomalies. …”
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ATIVIDADES COTIDIANAS, DEPOSIÇÃO DE REFUGO E AÇÃO DO ARADO: PROCESSOS DE FORMAÇÃO DO REGISTRO ARQUEOLÓGICO NO ESPAÇO DE UMA SENZALA DE CAMPOS DOS GOYTACAZES (RJ) by Isabela Cristina Suguimatsu, Luís Cláudio Pereira Symanski

“…The differences in the integrity patterns indicate that the archaeological record was differentially impacted by cultural formation processes. …”
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Phylogenomics of East Asian lineage within subgenus Anguinum (Allium, Amaryllidaceae): insights into its taxonomic puzzles and phylogenetic conflicts by Rui-Yu Cheng, Yuan Wang, Bo-Ni Song, Jin-Bo Tan, Jia-Hui Sun, Song-Dong Zhou, Xing-Jin He, Deng-Feng Xie

“…This study not only reveals the underlying causes of taxonomic controversies within the EAL but also provides critical insights into the unique phylogenetic patterns and evolutionary mechanisms shaping plant lineages in the HHMs biodiversity hotspot.…”
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Assessment of earthquake resistance of critical infrastructure objects, taking into account their own harmonics in the explosive spectrum of civil and military characters by V.V. Boiko, Yu.I. Voitenko, A.L. Han, T.V. Khlevniuk, Ye.A. Zahoruiko, O.V. Han

“…The article presents theoretical and experimental studies of the patterns of repeatability of seismic waves excited by man-made explosions to assess the earthquake resistance of critical infrastructure objects. …”
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Demographic, Clinical Features and Outcome Determinants of Thoracic Trauma in Sri Lanka: A Multicentre Prospective Cohort Study by Yasith Mathangasinghe, Iddagoda Hewage Don Saman Pradeep, Dhammike Rasnayake

“…We intended to describe patterns of thoracic trauma, demographic factors, clinical course, and predictors of outcome in selected tertiary care hospitals in Sri Lanka. …”
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Migrant parent-child separation in the first three years of life and mental health problems at preschool age: A cross-sectional study by Hailati Akezhuoli, Minghui Tan, Yuyin Ma, Xintian Liu, Jiayao Xu, Jingjing Lu, Xudong Zhou

“…This study aimed to determine the association of parent-child separation in the first three years and its specific patterns with mental health problems that emerged at preschool age. …”
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