High-coverage allele-resolved single-cell DNA methylation profiling reveals cell lineage, X-inactivation state, and replication dynamics by Nathan J. Spix, Walid Abi Habib, Zhouwei Zhang, Emily Eugster, Hsiao-yun Milliron, David Sokol, KwangHo Lee, Paula A. Nolte, Jamie L. Endicott, Kelly F. Krzyzanowski, Toshinori Hinoue, Jacob Morrison, Benjamin K. Johnson, Wanding Zhou, Hui Shen, Peter W. Laird

“…Abstract DNA methylation patterns at crucial short sequence features, such as enhancers and promoters, may convey key information about cell lineage and state. …”
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The Eocene–Oligocene Transition in the Paratethys: boreal water ingression and its paleoceanographic implications by M. Y. Kaya, M. Y. Kaya, H. Brinkhuis, H. Brinkhuis, C. Fioroni, S. G. Atasoy, A. Licht, D. Nürnberg, T. Vural

“…The stable isotopic shifts observed in benthic and planktic foraminifera <span class="inline-formula"><i>δ</i>¹⁸</span>O and <span class="inline-formula"><i>δ</i>¹³</span>C records at Karaburun align with global patterns but also reveal regional effects, such as freshwater influx and basin restriction, specific to the semi-restricted Paratethys. …”
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Identify suitable artificial groundwater recharge zones using hybrid deep learning models by Navaz Khalillollahi, Mohsen Isari, Hamed Faroqi, Kaywan Othman Ahmed, Kamran Nobakht Vakili, Miklas Scholz, Saad Sh. Sammeng

“…The second dataset enhanced the analysis by incorporating additional parameters related to climate patterns. In addition, two feature selection methods, namely Mutual Information (MI) and Random Forest (RF), were employed to identify the most significant factors. …”
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Potential biosecurity breaches in poultry farms: Presence of free-ranging mammals near laying-hen houses assessed through a camera-trap study by Giulia Graziosi, Caterina Lupini, Francesco Dalla Favera, Gabriella Martini, Geremia Dosa, Gloria Garavini, Giacomo Trevisani, Alessandro Mannelli, Elena Catelli

“…Given this background, this study aimed to identify mammal species occurring near laying-hen houses and characterize the spatiotemporal patterns of these visits. Seven camera traps were deployed for a year-long period in three commercial poultry farms in a densely populated poultry area in Northern Italy. …”
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A Feasibility Analysis of Wind Energy Potential and Seasonal Forecasting Trends in Thatta District: A Project to Combat the Energy Crisis in Pakistan by Jahangeer Khan Bhutto, Zhijun Tong, Tayyab Raza Fraz, Mazhar Baloch, Haider Ali, Jiquan Zhang, Xingpeng Liu, Yousef A. Al-Masnay

“…Box–Jenkins ARIMA and SARIMA models were applied to predict future wind patterns. This study revealed that Thatta district experienced sufficient wind speeds during the study period, with averages of 9.7 m/s, 7.6 m/s, 7.4 m/s, and 4.8 m/s for summer, autumn, spring, and winter, respectively. …”
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Attitudes toward lithium prescription among psychiatrists in Saudi Arabia: a cross-sectional study by Mohammad A. Alolayan, Mohammad A. Alolayan, Ahmad H. Almadani, Ahmad H. Almadani, Ghada K. Alrashed, Jamal Alothaim, Weam Hussein

“…Lithium is commonly recommended as a first-line treatment during the maintenance phase of BD. However, prescribing patterns for mood disorders vary among countries, with notable regional differences in lithium use.MethodsThis cross-sectional study included 287 psychiatrists and psychiatry trainees in Saudi Arabia. …”
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Application of flow field visualization technology in analysing the influence of nutrient solution flow on hydroponic lettuce growth by Bateer Baiyin, Yue Xiang, Yang Shao, Jung Eek Son, Kotaro Tagawa, Satoshi Yamada, Mina Yamada, Qichang Yang

“…Particle image velocimetry was employed to visualise the flow field, providing a deeper understanding of how flow patterns impact the root environment. In the early growth stage, lettuce under no flow conditions exhibited higher shoot and root biomass. …”
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AI-DBS study: protocol for a longitudinal prospective observational cohort study of patients with Parkinson’s disease for the development of neuronal fingerprints using artificial... by Martijn Beudel, Rick Schuurman, Rob M A de Bie, Deborah Hubers, Mariëlle J Stam, Martijn G J de Neeling, Bart J Keulen, Arthur W G Buijink, Bernadette C M van Wijk

“…The objective of the AI-DBS study is to identify patient-specific patterns of neuronal activity that are associated with the severity of motor symptoms of PD. …”
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Characterization and Early Response of the DEAD Gene Family to Heat Stress in Tomato by Yanyan Yan, Chao Yu, Bolun Xie, Hui Zhou, Caiyu Zhang, Li Tian

“…The expression of 37 out of 42 <i>SlDEAD</i> genes was responsive to heat stress induction. During the early stage of high-temperature treatment, they exhibited five distinct expression patterns. …”
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Revealing the role of U2AF1 in splicing regulation and chimeric RNA dynamics by Sangeen Khan, Yue Tang, Yangyang Guo, Jing Feng, Hui Wu, Zhenguo Song, Chengjuan Zhang, Fujun Qin

“…U2AF1 plays a critical role in the recognition and processing of 3ʹ splice sites during pre-mRNA splicing, thereby contributing to the regulation of gene expression and the generation of protein diversity. …”
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Time-varying synergy/redundancy dominance in the human cerebral cortex by Maria Pope, Thomas F Varley, Maria Grazia Puxeddu, Joshua Faskowitz, Olaf Sporns

“…Although larger subsets cannot be contained in a single functional network, similar patterns of instantaneous disintegration mark when they become synergistic. …”
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Inter-seizure variability in thalamic recruitment and its implications for precision thalamic neuromodulation by Pariya Salami, Angelique C. Paulk, Daniel J. Soper, Pierre Bourdillon, Peter N. Hadar, Omar A. Alamoudi, Nathaniel D. Sisterson, R. Mark Richardson, Sandipan Pati, Sydney S. Cash

“…Results We show that seizures with <2 Hz synchronized-spiking patterns do not spread early to the thalamus, while seizures starting with faster activity (<20 Hz) spread early to all thalamic areas. …”
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Pathogenetic and clinical signifcance of EpCАM expression features in tumors and circulating tumor cells by V. M. Perelmuter, L. A. Tashireva, E. S. Grigoryeva, V. V. Alifanov, E. S. Pudova, A. V. Buzenkova, M. V. Zavyalova, N. V. Cherdyntseva

“…Features of EpCAM expression in normal epithelial tissues, during regeneration, and in dysplasia/ neoplasia as well as carcinomas were carefully outlined. …”
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Performance, adaptability, and multi‐trait stability of rice varieties (Oryza sativa L.) in rainfed conditions by Md. Kawsar Alam Nadim, Motabber Rahman, Md. Rayhan Sikder, Sourav Adhikary, Nusrat Binta Atiq, Md. Mahbubul Alam, Mariom Mitu, Tasnim Zerin Khan, Md. Rashedul Islam, Zakaria Alam, Sanjida Akter

“…A study was conducted in five rainfed districts during the 2022 Aman season. The objective was to assess grain yield performance, adaptation patterns, and identify a stable rice variety using multiple trait evaluations. …”
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Proanthocyanidin-enriched cranberry extract induces resilient bacterial community dynamics in a gnotobiotic mouse model by Catherine C. Neto, Benedikt M. Mortzfeld, John R. Turbitt, Shakti K. Bhattarai, Vladimir Yeliseyev, Nicholas DiBenedetto, Lynn Bry, Vanni Bucci

“…We show that daily administration of CJE induces distinct dynamic patterns in bacterial abundances during and after treatment, before recovering resiliently to pre-treatment levels. …”
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Pan-Genome-Based Characterization of the SRS Transcription Factor Family in Foxtail Millet by Ruimiao Li, Cuiyun Lei, Qiang Zhang, Xiaomeng Guo, Xiting Cui, Xingchun Wang, Xukai Li, Jianhua Gao

“…We identified SRS members and analyzed their intra-species distribution patterns, including copy number variation (CNV) and interchromosomal translocations. …”
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Use of intraoperative ex VIVO fluorescence confocal microscopy to identify ganglionic bowel in Hirschsprung’s DISEASE: A case series by Donatella Di Fabrizio, Irene Tavolario, Francesca Mastroberti, Edoardo Bindi, Alessandra Filosa, Gaia Goteri, Giovanni Cobellis

“…At 12-month follow-up, the child had normal stooling patterns and appropriate weight gain. Conclusion: Intraoperative ex vivo fluorescence confocal microscopy seems to be a fast and reliable method for the identification of ganglionic bowel during the pull-through procedure for the management of Hirschsprung disease.…”
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Altered miRNA expression in the lesions of cutaneous leishmaniasis caused by L. major and L. tropica with insights into apoptosis regulation by Taha Masoudsinaki, Shima Hadifar, Hamzeh Sarvnaz, Mohammad Farahmand, Nasrin Masoudzadeh, Vahid Mashayekhi Goyonlo, Mohammadali Kerachian, Reza Erfanian Salim, Mourad Barhoumi, Seyed Latif Mousavi Gargari, Hossein Heydari, Sima Rafati

“…Our results showed that miR-155-5p, miR-5011-5p, and miR-6785-5p were significantly upregulated (P < 0.05) in L. tropica-infected patients. Similar expression patterns for miR-155-5p and miR-6785-5p, but with a higher magnitude, were found in the lesions of CL patients infected with L. major. …”
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Genome-Wide Identification of miRNAs in Oily Persimmon (<i>Diospyros oleifera</i> Cheng) and Their Functional Targets Associated with Proanthocyanidin Metabolism by Meng Zhang, Rong Wu, Xinlong Hu, Zhengrong Luo, Qinglin Zhang, Sichao Yang

“…The qRT-PCR assay was performed to elucidate the potential expression patterns of precursor miRNA and their targets during fruit development, and one target gene, <i>DkMYB22</i>, of miR2911 was verified to promote the conversion of soluble tannins into insoluble tannins involved in the deastringency in persimmons. …”
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Estimating the prevalence of six common respiratory viral infections in Zhangzhou, China using nasopharyngeal swabs in adults and throat swabs in Children by Yuanjun Zeng, Guowei Wang, Huicong Yang, Hongmei Li, Yueli Guo, Huili Liu, Xiaojun Xu, Chunbin Zhang

“…The study highlights the distinct age, sex, and seasonal patterns of six common respiratory viral infections in Zhangzhou, China. …”
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