Interferon and B-cell Signatures Inform Precision Medicine in Lupus Nephritis by Ioannis Parodis, Julius Lindblom, Daniel Toro-Domínguez, Lorenzo Beretta, Maria O. Borghi, Jessica Castillo, Elena Carnero-Montoro, Yvonne Enman, Chandra Mohan, Marta E. Alarcón-Riquelme, Guillermo Barturen, Dionysis Nikolopoulos, Lorenzo Beretta, Barbara Vigone, Jacques-Olivier Pers, Alain Saraux, Valérie Devauchelle-Pensec, Divi Cornec, Sandrine Jousse-Joulin, Bernard Lauwerys, Julie Ducreux, Anne-Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez-Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez-Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Rafaela Ortega-Castro, Ma Angeles Aguirre-Zamorano, Alejandro Escudero-Contreras, Ma Carmen Castro-Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López-Berrio, Rocío Aguilar-Quesada, Héctor Navarro-Linares

“…Conclusion: IFN upregulation and B and plasma cell gene dysregulation patterns revealed 3 subgroups of LN, which may not necessarily represent distinct disease phenotypes but rather phases of the inflammatory processes during a renal flare, providing a conceptual framework for precision medicine in LN.…”
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Unique metabolic regulation of micromeres contributes to gastrulation in the sea urchin embryo by Shakson Isaac, Douglas Dubosky, Ashley Waldron, Natsuko Emura, Aidan Furze, Kavya Rao, Masaru Mori, Ashok Ragavendran, Hideki Makinoshima, Mamiko Yajima

“…Abstract During development, a group of cells called organizers plays critical roles by sending signals to adjacent cells and controlling embryonic and tissue patterning. …”
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Identifying people with post-COVID condition using linked, population-based administrative health data from Manitoba, Canada: prevalence and predictors in a cohort of COVID-positiv... by Jennifer E Enns, Alan Katz, Alexander Singer, Yoav Keynan, Lisa Lix, Kendiss Olafson, Randy Walld, Nathan C Nickel, Okechukwu Ekuma, Sarvesh Logsetty, Marcelo Urquia, Diana C Sanchez-Ramirez, Leona Star, Rae Spiwak, Teresa Cavett, Marina Yogendran, Jillian Waruk, Surani Matharaarachichi

“…Additional PCC cases were identified using predictive modelling to assess patterns of health service use, including physician visits, emergency department visits and hospitalisation for any reason (n=4155).Outcomes We measured PCC prevalence as % PCC cases among Manitobans with positive tests and identified predictive factors associated with PCC by calculating odds ratios with 95% confidence intervals, adjusted for sociodemographic and clinical characteristics (aOR).Results Among 66 365 Manitobans with positive tests, we identified 15 471 (23%) as having PCC. …”
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Impact of sterile Aedes aegypti males releases on vector dynamics: insights from Malaysian field trials by Wasi Ahmad Nazni, Guat-Ney Teoh, Mohd Adnan Nuradila, Shaikh Ismail Shaikh Norman Hakimi, Maheswaran Tanusshni, Mohd Azam Muhammad Arif, Achim Nurfarahin Hanini, Irfan Ahmad Shazia, Aik-Meng Tan, Hamzah Rabizah, Mohamad Dzomir Ahmad Zainuri, Asim Hasnor Hadi, Ahmad Norazah, Han-Lim Lee, Hamidou Maiga, Jeremy Bouyer, Yoon-Ling Cheong

“…Spatial clustering revealed no initial clustering, though clustering patterns emerged over time in KT. Conclusions SIT effectively suppressed Ae. aegypti populations and supported dengue control. …”
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Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response. by Christoph Schell, Oliver Kretz, Andreas Bregenzer, Manuel Rogg, Martin Helmstädter, Ulrike Lisewski, Michael Gotthardt, Pierre-Louis Tharaux, Tobias B Huber, Florian Grahammer

“…Previous studies in the zebrafish pronephros postulated a potential role of CXADR for the terminal differentiation of glomerular podocytes and correct patterning of the elaborated foot process architecture. …”
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The expression of irx7 in the inner nuclear layer of zebrafish retina is essential for a proper retinal development and lamination. by Yuqing Zhang, Yifan Yang, Caleb Trujillo, Wenxuan Zhong, Yuk Fai Leung

“…Irx7, a member in the zebrafish iroquois transcription factor (TF) family, has been shown to control brain patterning. During retinal development, irx7's expression was found to appear exclusively in the inner nuclear layer (INL) as soon as the prospective INL cells withdraw from the cell cycle and during retinal lamination. …”
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Remote work – the new normal needs more research by Annina Ropponen

“…Remote office work: changing work patterns in space and time. Commun ACM. 1983;26(3):182-7. https://doi.org/10.1145/358061.358068 8. …”
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Influence of structural setting, depositional environment and differential diagenesis on reservoir quality of the Xixiangchi formation in the central and southern Sichuan Basin, Ch... by Shizhen Chen, Shizhen Chen, Shizhen Chen, Huaguo Wen, Huaguo Wen, Huaguo Wen, Xiang Li, Xiang Li, Xiang Li, Fei Huo, Bowen Mo, Bowen Mo, Bowen Mo, Jintong Liang, Jintong Liang, Jintong Liang, Lian Duan, Lian Duan, Lian Duan

“…All dolomite types exhibit rare earth element patterns and isotopic signatures (δ13C: −1.39‰ ± 0.67‰ to - 1.23‰ ± 0.71‰; δ18O: −8.62‰ ± 1.18‰ to - 8.15‰ ± 0.98‰) comparable to coeval micritic limestones, indicating formation from evaporatively-concentrated seawater or marine-derived fluids. …”
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Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract by Mohammad Jad Moussa, Georges C. Tabet, Arlene O. Siefker‐Radtke, Lianchun Xiao, Nathaniel R. Wilson, Jianjun Gao, Christopher J. Logothetis, Petros Grivas, Byron Lee, Amishi Y. Shah, Pavlos Msaouel, Roger Li, Leticia Campos Clemente, Jianping Zhao, Nizar M. Tannir, Ashish M. Kamat, Donna E. Hansel, Charles C. Guo, Matthew T. Campbell, Omar Alhalabi

“…Here, we evaluate the predictors and patterns of relapse after surgery. Materials and Methods We identified a definitive‐surgery cohort (n = 224) from an institutional database of patients with cT1‐T4NxM0 SCNEC‐URO treated in 1985–2021. …”
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Cladolosides of Groups S and T: Triterpene Glycosides from the Sea Cucumber <i>Cladolabes schmeltzii</i> with Unique Sulfation; Human Breast Cancer Cytotoxicity and QSAR by Alexandra S. Silchenko, Elena A. Zelepuga, Ekaterina A. Chingizova, Ekaterina S. Menchinskaya, Kseniya M. Tabakmakher, Anatoly I. Kalinovsky, Sergey A. Avilov, Roman S. Popov, Pavel S. Dmitrenok, Vladimir I. Kalinin

“…This suggests that the enzymatic processes of sulfation and <i>O</i>-methylation that occur during the biosynthesis of glycosides can compete with each other. …”
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Normative Database of Spatiotemporal Gait Metrics Across Age Groups: An Observational Case–Control Study by Lianne Mobbs, Vinuja Fernando, R. Dineth Fonseka, Pragadesh Natarajan, Monish Maharaj, Ralph J. Mobbs

“…Our findings offer valuable reference points for clinicians to distinguish between healthy and pathological gait patterns, facilitating early detection and intervention for gait-related disorders. …”
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Determinants and Experiences of Care‐Seeking for Childhood Pneumonia in a Rural Indian Setting: A Mixed‐Methods Study by Barsha Gadapani Pathak, Sarmila Mazumder, Yasir Bin Nisar, Aditya Bhatt, Mandeep Singh, Tarun Madhur, Ingvild Fossgard Sandøy

“…Data on socio‐demographic characteristics, health insurance, care‐seeking patterns and provider preferences were collected. Directed acyclic graphs (DAGs) identified potential confounders in the association between care‐seeking behaviour and key exposure variables. …”
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GUEST EDITORS’ NOTE by Piero Amodio, Edward W. Legg, Ljerka Ostojić

“…This paper also illustrates how similar patterns may be observed in the timings of human behaviour and calls on researchers to better investigate the timing and organisation of behaviour – one part of which could potentially be achieved through secondary data analysis of timings in open behavioural data sets. …”
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Path and Practice of Gap Management in National Parks: A Comparison Between China and the US and Inspirations Therefrom by Yun MA, Siyuan HE

“…As inholdings often originate from land transfers during the territorial expansion of the US, they create fragmented ownership patterns, complicating federal land management. …”
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Study on the influence mechanism and correlation model of rockfall parameters on indentation morphology by LI Hao, WANG Dong-po, YAN Shuai-xing, LI Wei, CHEN Hui, HE Si-ming

“…By integrating high - speed photography, laser scanning, and point - cloud automatic extraction technologies, a comprehensive analysis of the morphological evolution patterns and classification characteristics of rockfall indentations under different impact angles was conducted. …”
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Vaimse heaolu komponendid muusikuks kujunemise teel. Toimetulek esinemisärevuse ja vaimsete blokkidega Eesti Muusika- ja Teatriakadeemia viiuli-, vioola- ja klaveritudengite hulgas... by Jelizaveta Bukina, Janika Mesi, Marju Raju

“…These blocks function as metaphorical walls (Baumeier 1984), where a musician, despite having no physical limitations, struggles to perform certain musical material due to self-doubt and negative thought patterns. While the topic of mental blocks has been widely explored in sports psychology (Beilock & Gray 2007; Walker 2021), research specifically focusing on musicians remains scarce. …”
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Recent large-inland-lake outbursts on the Tibetan Plateau: processes, causes, and mechanisms by F. Xu, F. Xu, Y. Liu, G. Zhang, P. Zhao, R. I. Woolway, Y. Zhu, J. Ju, T. Zhou, T. Zhou, X. Wang, X. Wang, W. Chen

“…For Zonag Lake, thermodynamic effects, i.e., changes in the atmospheric moisture, are the most important, while for Selin Co, dynamical effects, i.e., the vertical moisture motion induced by changes in atmospheric circulation, dominate the precipitation patterns. Large-lake outbursts on the inner Tibetan Plateau are expected to increase in the near future due to the warmer and wetter climate, and urgent policy planning is needed to mitigate the potential future lake-induced flood damage.…”
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Asymmetrical Time-Lagged Response of Vegetation to Drought and Extreme Precipitation Across China by Wenli Lai, Yongxiang Chen, Jie Zhang, Huai Yang

“…These results suggest that the lagging responses of vegetation to extreme precipitation and droughts exhibit opposing regional patterns across China.…”
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Involvement of Lgl and Mahjong/VprBP in cell competition. by Yoichiro Tamori, Carl Uli Bialucha, Ai-Guo Tian, Mihoko Kajita, Yi-Chun Huang, Mark Norman, Nicholas Harrison, John Poulton, Kenzo Ivanovitch, Lena Disch, Tao Liu, Wu-Min Deng, Yasuyuki Fujita

“…In Drosophila, Mahjong is an essential gene, but zygotic mahjong mutants (mahj(-/-)) do not have obvious patterning defects during embryonic or larval development. …”
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Development of an MRI based artificial intelligence model for the identification of underlying atrial fibrillation after ischemic stroke: a multicenter proof-of-concept analysisRes... by Zijie Zhang, Yang Ding, Kaibin Lin, Wenli Ban, Luyue Ding, Yudong Sun, Chuanliang Fu, Yihang Ren, Can Han, Xue Zhang, Xiaoer Wei, Shundong Hu, Yuwu Zhao, Li Cao, Jun Wang, Saman Nazarian, Ying Cao, Lan Zheng, Min Zhang, Jianliang Fu, Jingbo Li, Xiang Han, Dahong Qian, Dong Huang

“…More importantly, our proposed model identified all the AF patients that were diagnosed with Holter monitoring during index stroke admission. Interpretation: Our work suggested a potential association between brain ischemic lesion pattern on MR images and underlying AF. …”
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