The Italian contribution to the Synoptic Arctic Survey programme: the 2021 CASSANDRA cruise (LB21) through the Greenland Sea Gyre along the 75° N transect by M. Bensi, G. Civitarese, D. Borme, C. Caroppo, G. Caruso, F. Cerino, F. Decembrini, A. de Olazabal, T. Diociaiuti, M. Giani, V. Kovacevic, M. Kralj, A. Lo Giudice, G. Maimone, M. Monti, M. Papale, L. Patrolecco, E. Putelli, A. C. Rappazzo, F. Relitti, C. Rizzo, C. Rizzo, F. Spataro, V. Tirelli, C. Turetta, M. Azzaro

“…The enzyme patterns vary spatially, with activity peaks at the ends and in the middle of the transect. …”
Get full text

Genome-wide identification of sugarcane HAT gene family and functional analysis of ScHAT1 in stress response by Shijiang Cui, Shiwei Yang, Ping Zhao, Shoujian Zang, Zhenxiang Li, Peixia Lin, Wanying Zhao, Yuanyuan Zhang, Dongjiao Wang, Youxiong Que, Qibin Wu

“…Notably, stress-responsive elements were significantly enriched in the promoter regions of the HAM subfamily. Expression pattern analysis revealed that several sugarcane HAT genes responded to smut (Sporisorium scitamineum) and drought stress, with ShHAT24 showing significant upregulation under both stress conditions. …”
Get full text

Left-right function of dmrt2 genes is not conserved between zebrafish and mouse. by Raquel Lourenço, Susana S Lopes, Leonor Saúde

“…However, nothing was known about its role during left-right patterning in the lateral plate mesoderm or in the symmetric synchronization of somite formation.…”
Get full text

Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions by Diane Damotte, Laurence Zitvogel, Marco Alifano, Marie-Caroline Dieu-Nosjean, Gabriela Bindea, Jeremy Goc, Jules Russick, Pierre-Emmanuel Joubert, Mélanie Gillard-Bocquet, Carine Torset, Maxime Meylan, Florent Petitprez, Marie-Agnes Dragon-Durey, Solenne Marmier, Aditi Varthaman, Nathalie Josseaume, Claire Germain, Pierre Validire, Ludovic Fournel, Audrey Lupo, Isabelle Cremer

“…First, transcriptomic analysis reveals significant changes related to migratory pattern with a downregulation of sphingosine-1-phosphate receptor 1 (S1PR1) and CX3C chemokine receptor 1 (CX3CR1) and overexpression of C-X-C chemokine receptor type 5 (CXCR5) and C-X-C chemokine receptor type 6 (CXCR6). …”
Get full text

Mariculture site selection based on water quality, cultivation and ecological condition by T.K. Arifin, Y. Yulius, M. Ramdhan, O. Johan, D.P. Gunawan, A. Heriati, E. Mustikasari, R. Rahmania, D. Purbani, I. Dillenia, S.B. Agus, R. Asaf, M. Hatta, I. Marzuki, R. Akhwady, A. Sufyan, H. Fihrin, E. Septiningsih, A. Wahyono, A. Athirah

“…Spatial analysis employing Geographic Information System applications is used to evaluate the appropriateness of locations for mariculture.FINDINGS: The distribution pattern of primary productivity is strongly influenced by the distribution of phytoplankton and the highest concentration values are located in coastal waters and small islands. …”
Get full text

Identifying and Prioritizing Creative Tourism Attractions in the Life of the Nomads from the Guest-Host Perspective (Case study: Bakhtiari Tribe, Khuzestan Province) by Mehrnoosh bastenega, Anahita Azarbod

“…The study data was collected based on the decision matrix pattern, which includes options and indicators, based on the subjective judgments of a 15-person sample of the statistical population selected by the snowball method. …”
Get full text

Towards interpretable drug interaction prediction via dual-stage attention and Bayesian calibration with active learning by Rongpei Li, Yufang Zhang, Heqi Sun, Shenggeng Lin, Guihua Jia, Yitian Fang, Chen Zhang, Xiaotong Song, Jianwei Zhao, Lyubin Hu, Yajing Yuan, Xueying Mao, Jiayi Li, Aman Kaushik, Dandan An, Dongqing Wei

“…Conclusion We present DABI-DDI, an integrated feature extraction framework that successfully addresses key challenges in DDIs prediction through three major innovations: Temporal pattern recognition, reducing false positives, and biological interpretability. …”
Get full text

Development of Dihydroquercetin-based Oral tablets and Evalution of the General Toxic Effect by S. A. Abdulrazzak, A. N. Vorobyev, N. I. Sinitsyna, I. V. Sharutin, O. V. Menshova, E. V. Elizarova, Yu. V. Ivanov, A. S. Karamyan, R. A. Abramovich, O. G. Potanina, K. M. Sakanyan

“…The frequency of the examination depends on the severity of the intoxication pattern, but not less often than on the 2nd, 7th and 14th day of the experiment. …”
Get full text

Mapping the viral battlefield: SARS-CoV-2 infection dynamics among healthcare workers in Brazil by Antonio Luiz Dal Bello Gasparoto, Samara Vilas-Bôas Graeff, Wellyngton Matheus de Souza Santiago, Danielle Gomes da Silva, Thaynara Azevedo dos Santos, Leandro Martin Paulino, Wellington Santos Fava, Fernanda Paes Reis, Claudia Stutz, Adriana de Oliveira França, Ana Tereza Gomes Guerrero Moureau, Camila Amato Montalbano, Everton Ferreira Lemos, Crhistinne Cavalheiro Maymone Gonçalves, Carlos Alberto Bento Júnior, Rodrigo Pires Dallacqua, Julio Croda, Aline Pedroso Lorenz, Cristina Souza, Taynara Nogueira Martins, Kassia Roberta Nogueira da Silva, Alda Maria Teixeira Ferreira, Adriana Carla Garcia Negri, Anamaria Mello Miranda Paniago, Ana Rita Coimbra Motta-Castro, James Venturini, Ana Paula da Costa Marques, Sandra Maria do Valle Leone de Oliveira

“…The infection dynamics mirrored the pattern observed in the general population. Conclusion One-third of the professionals in the followed cohort were infected. …”
Get full text

Constitutive model of metal rubber material considering plastic accumulation behavior by FENG Zhipeng, YANG Fang, FU Hailong, AI Shigang, WANG Yue, YUAN Liangyang

“…Due to the complex and varied interlocking patterns of internal metallic helical coils during cold compression molding, residual stresses typically exist after forming. …”
Get full text

The impact of war on people with type 2 diabetes in Ukraine: a survey studyResearch in context by Oksana Sulaieva, Viktoriia Yerokhovych, Sergii Zemskov, Iuliia Komisarenko, Vitalii Gurianov, Volodymyr Pankiv, Oleksandr Tovkai, Tetyana Yuzvenko, Violetta Yuzvenko, Andrii Tovkai, Zlatoslava Shaienko, Tetyana Falalyeyeva, Nadiya Skrypnyk, Taras Romaniv, Nadiya Pasyechko, Taras Krytskyy, Solomiia Danyliuk, Andrii Klantsa, Dmytro Krasnienkov, Oleksandr Gurbych, Nazarii Kobyliak

“…HbA1c levels demonstrated a time-dependent pattern of growth, reflecting the cumulative effect of war-related factors on T2D patients’ health. …”
Get full text

Nodal-dependent mesendoderm specification requires the combinatorial activities of FoxH1 and Eomesodermin. by Christopher E Slagle, Tsutomu Aoki, Rebecca D Burdine

“…However, loss of FoxH1 in several species does not reliably cause the full range of loss-of-Nodal phenotypes, indicating that Nodal signals through additional transcription factors during early development. We investigated the FoxH1-dependent and -independent roles of Nodal signaling during mesendoderm patterning using a novel recessive zebrafish FoxH1 mutation called midway, which produces a C-terminally truncated FoxH1 protein lacking the Smad-interaction domain but retaining DNA-binding capability. …”
Get full text

Correlation of excess salt intake identified by the survey with urine sodium level and blood pressure: data of ESSE-RF study by Yu. A. Balanova, V. A. Kutsenko, S. A. Shalnova, A. E. Imaev, A. V. Kapustina, G. A. Muromtseva, S. E. Evstifeeva, N. S. Karamnova, S. A. Maksimov, E. B. Yarovaya, O. M. Drapkina, A. N. Redko, S. N. Alekseenko, S. V. Gubarev, I. A. Viktorova, M. A. Livzan, I. A. Grishechkina, M. Yu. Rozhkova, N. N. Prishchepa, N. N. Vezikova, I. S. Skopets, S. S. Yakushin, E. V. Filippov, N. V. Dobrynina, N. N. Nikulina, K. G. Pereverzeva, K. A. Moseichuk

“…One point on the scale increases the Na+ level by an average of 7,51 (5,01-10,02) mmol/l, SBP by an average of 0,74 (0,41-1,07) mm Hg and the odds of HTN by 1,1 (1,06-1,15) times (p<0,001 for all).Conclusion. In the pattern of ESI components, processed meat and sausage products take first place in terms of association strength with urine sodium. …”
Get full text

Regional lymph node invasion in pediatric non-rhabdomyosarcoma soft tissue sarcoma: an international cohort study from the International Soft Tissue Sarcoma ConsortiumResearch in c... by Daniel Orbach, Matthieu Carton, Amadeus T. Heinz, Lise Borgwardt, J Herve Brisse, Carlo Morosi, Erin R. Rudzinski, Akmal Safwat, Monika Sparber-Sauer, Stephanie Terezakis, Andrea Ferrari, Aaron R. Weiss, William H. Meyer, David O. Walterhouse, Timothy B. Lautz

“…We therefore to analyze the rate of N1 at diagnosis, the pattern of nodal relapse, and the prognostic impact of N1 in pediatric patients with NRSTS. …”
Get full text

A very early clinical response to treatment with the Janus kinase inhibitor tofacitinib in patients with active rheumatoid arthritis: the dynamics of pain and central sensitization... by A. E. Karateev, E. S. Filatova, E. Yu. Pogozheva, V. N. Amirdzhanova, E. L. Nasonov, A. M. Lila, V. I. Mazurov, A. Yu. De, A. A. Baranov, N. A. Lapkina, G. V. Lukina, N. A. Kiryukhina, S. Yu. Davidyan, T. S. Salnikova, R. R. Samigullina, D. S. Chakieva, I. M. Marusenko, O. V. Semagina, M. Yu. Semchenkova, A. F. Davydova, E. V. Kalinina

“…The limitation of this investigation was its open observer design pattern.Conclusion. The use of the JK inhibitor TOFA can achieve a rapid analgesic effect, inter alia due to its effect on CS and NPC.…”
Get full text

How to Apply the Sequential Correction Technique to Treatment of Congenital Cervicothoracic Scoliosis: A Technical Note and Case Series by Saihu Mao, Kai Sun, Song Li, Jie Zhou, Hongda Bao, Benlong Shi, Xu Sun, Zhen Liu, Yong Qiu, Zezhang Zhu

“…ABSTRACT Objective Hemivertebrae in the cervicothoracic junction in the pediatric population are treated conventionally with a two‐rod instrumentation pattern. However, the increase in complexity, severity, and immaturity of osseous malformation in the cervicothoracic spine presents additional challenges in construct planning. …”
Get full text

Toxic and infectious lung injury differential diagnosis specifics in oncohematological patients by V. R. Yanbukhtina, I. S. Zyuzgin, T. V. Shneyder, P. K. Khorosheva, A. A. Zver’kova, I. A. Borovichkov, G. B. Kuchma, E. A. Kulagin, L. V. Stel’makh, A. G. Smirnova, Yu. Yu. Vlasova, E. V. Morozova, Yu. D. Rabik, I. S. Moiseev, V. I. Trofimov

“…The most common radiological pattern (71 % of cases in each group) was ground-glass opacities, in patients of the second group often combined with infiltrative changes and thickening of the bronchial walls (in 53 and 42 % of cases respectively). …”
Get full text

THE IMPACT OF ADEQUATE PSYCHOPHARMACOTHERAPY ON THE EFFICIENCY OF TREATMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS by A. A. Abramkin, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, E. L. Nasonov

“…The diagnosis of MDs was based on the ICD-10 codes, by applying a semi-structured interview and the Hospital Anxiety and Depression Scale. Changes in the pattern and severity of ADS were evaluated using the Hamilton Anxiety Scale and the Montgomery–Asberg Depression Rating Scale. …”
Get full text

Association between physical activity and risk of anxiety: a dose-response meta-analysis of 11 international cohortsResearch in context by Xuesi Li, Weicong Chen, Zijiao Zhang, Zheng Li, Xianming Fan, Tongyu Ma, Shunjing Ding, Fangyu Yang, Jianbo Lei

“…In subgroup analysis, studies with follow-up time ≤5 years (I2 = 68.4%; P = 0.023) exhibited a more typical J-shaped pattern, with a smaller maximum benefit dose of 12.5 MET-h/week and a greater reduction in anxiety risk, up to 49% (95% CI: 35%–59%); anxiety risk significantly increases above 23.5 MET-h/week. …”
Get full text

The Effect of Land Use Change on Runoff Using the SWAT Model in the Tajan Watershed by hayede bayani, ali bagheri, Davod Akbari Nodehi, Valiollah Karimi

“…However, the effect of the pattern of landscape and the trend of its characteristics has not been observed to date. …”
Get full text