Spatiotemporal requirements of nuclear β-catenin define early sea urchin embryogenesis. by Guy Lhomond, Michael Schubert, Jenifer Croce

“…Establishment of the 3 primordial germ layers (ectoderm, endoderm, and mesoderm) during early animal development represents an essential prerequisite for the emergence of properly patterned embryos. β-catenin is an ancient protein that is known to play essential roles in this process. …”
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Markers of T cell activation and exhaustion in plasma are associated with persistent symptoms up to 18 months following mild SARS-CoV-2 infection by Thor Ueland, Thor Ueland, Thor Ueland, Rebecca Jane Cox, Rebecca Jane Cox, Rebecca Jane Cox, Annika E. Michelsen, Annika E. Michelsen, Elisabeth Berg Fjelltveit, Elisabeth Berg Fjelltveit, Kari Otterdal, Tuva Dahl, Fan Zhou, Rebecca Elyanow, Pål Aukrust, Pål Aukrust, Pål Aukrust, Bjørn Blomberg, Bjørn Blomberg, Bente E. Halvorsen, Bente E. Halvorsen, Nina Langeland, Nina Langeland

“…(ii) Cases with memory problems at 12–18 months had increased sLAG-3 iii) sCD25 correlated with SARS-CoV-2 antibody titers and microneutralization titers only in cases with PCC while sTIM-3 correlated with these parameters irrespectively of symptoms. iv) Although hospitalized patients had markedly elevated levels of T cell activation/exhausting markers during follow-up, there was no relation to PCC symptoms.ConclusionOur study indicates a role for T cell activation/exhaustion in PCC following home isolated COVID-19 infection, with somewhat different patterns of sCD25, sTIM-3 and sLAG-3, but not in hospitalized COVID-19 patients where disease severity may be more important.…”
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Integrating community perspectives to improve survey completion rates in public health research by refining controversial survey elements by Arleth A. Escoto, Angel Lomeli, Maria Linda Burola, Breanna Reyes, Ana Perez-Portillo, Scarlet Flores, Kayleigh Kornher, Norma Porras, Ariel Cohen, Linda Salgin, Borsika A. Rabin, Louise C. Laurent, Marva Seifert, Nicole A. Stadnick

“…This study used cognitive interviews (CIs), a methodological tool that can aid in developing and refining elements for multi-faceted assessments, and previous survey response patterns to refine, streamline, and increase response rates of RADx-UP Common Data Elements (CDEs) for survey/questionnaire use. …”
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Genome-wide identification and characterization of soybean GH9 endo-1,4-β-glucanases by Weimin Zhan, Huijuan Huang, Zaipan Cai, Zhenwei Zhao, Xuefu Lin, Yize Peng, Zhicheng Dong, Di Qin, Di Qin, Li Jiang

“…The GmGH9B/C members display complex splicing patterns. GmGH9As contain typical transmembrane structural domains, while GmGH9Cs uniquely includes the carbohydrate-binding module 49 (CBM49) and signal peptide. …”
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Enhancing wheat resilience in subtropical agroecosystems through climate-resilient agriculture strategies by Raj Kumar Jat, Vijay Singh Meena, Vijay Singh Meena, S. Pazhanisamy, R.K. Sohane, R.K. Jha, R.N. Singh, Shubham Durgude, Suneel Kumar, Illathur R. Reddy, Kajod Mal Choudhary, Sunita Kumari Meena, Brijendu Kumar, Brijendu Kumar, Umesh N. Umesh, Ranjan K. Singh, Ranjan K. Singh, Ravikant Chaubey, Mukesh Kumar, Vinod Kumar, Kumari Sharda, Kumari Sharda, Susheel Singh, Rama K. Singh, Rama K. Singh, Seema Kumari, Seema Kumari, K.M. Singh, Govind Kumar, Ravindra K. Tiwari, Vinita Kashyap, Suneeta Kushwaha, Sripriya Das, Prem Prakash Gautam, Shubham Bhagat, Shubham Bhagat, Rodda C. Devi, Rodda C. Devi, Amit K. Lenka, Bharati Upadhaya, Sumit K. Singh, Sanchita Ghosh, Anup Das

“…Wheat production in subtropical agroecosystems is increasingly challenged by climate-induced stresses such as lodging, terminal heat, and erratic rainfall patterns. This study was conducted during the 2023–2024 rabi season across eight locations, namely, the Borlaug Institute for South Asia (BISA) Research Station at Pusa and seven project hubs located in the districts of Munger, Nawada, Nalanda, Katihar, Purnea, Samastipur, and Vaishali in Bihar, India, and evaluated climate-resilient agronomic strategies to enhance wheat resilience and productivity. …”
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Spatial and Seasonal Variation and the Driving Mechanism of the Thermal Effects of Urban Park Green Spaces in Zhengzhou, China by Yuan Feng, Kaihua Zhang, Ang Li, Yangyang Zhang, Kun Wang, Nan Guo, Ho Yi Wan, Xiaoyang Tan, Nalin Dong, Xin Xu, Ruizhen He, Bing Wang, Long Fan, Shidong Ge, Peihao Song

“…We calculated vegetation characteristic indices (VCIs) and landscape patterns (LMs) and employed boosted regression tree models to explore their relative contributions to land surface temperature (LST) across different seasons. …”
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Critical contributions of neuronal subtypes to pediatric drug-resistant focal dysplasia by Yujie Zhang, Lin Li, Fengjun Zhu, Xinyang Zhang, Dan Xia, Qiuling Miao, Cheng Zhong, Cheng Zhong, Shuli Liang, Dezhi Cao, Dezhi Cao, Huafang Zou, Jing Duan, Yousheng Shu, Yi Yao, Jianming Song, Songnian Hu, Jianxiang Liao, Jianxiang Liao, Qiang Zhou

“…In addition, astrocyte subtype 4 exhibited distinct metabolic characteristics and interaction patterns with neuronal subtypes, which suggests their significant role in epilepsy pathophysiology. …”
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Establishment of somatic embryogenesis regeneration system and transcriptome analysis of early somatic embryogenesis in litchi by Yaqi Qin, Bo Zhang, Shiqian Wang, Wuyan Guo, Zhike Zhang, Yonghua Qin, Jietang Zhao, Guibing Hu

“…Furthermore, transcriptome analysis was performed on embryogenic callus (EC), globular embryo (GE), and heart embryo (HE) to explore the molecular mechanisms of early somatic embryogenesis. 2,587 common differentially expressed genes (DEGs) between EC_vs_GE and EC_vs_HE were identified, and the expression patterns of these common DEGs were separated into twelve major clusters. …”
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The resurgence of Lassa fever in Nigeria: economic impact, challenges, and strategic public health interventions by Stanley Chinedu Eneh, Stanley Chinedu Eneh, Stanley Chinedu Eneh, Chidera Gabriel Obi, Chidera Gabriel Obi, Udokang Ephraim Ikpongifono, Udokang Ephraim Ikpongifono, Zakariya’u Dauda, Zakariya’u Dauda, Samson Adiaetok Udoewah, Samson Adiaetok Udoewah, Collins Chibueze Anokwuru, Collins Chibueze Anokwuru, Francisca Ogochukwu Onukansi, Francisca Ogochukwu Onukansi, Ogechi Vinaprisca Ikhuoria, Ogechi Vinaprisca Ikhuoria, Temitope Olumuyiwa Ojo, Chukwuocha Uchechukwu Madukaku, Ibuchukwu Nkeonyenasoya Orabueze, Ibuchukwu Nkeonyenasoya Orabueze, Amara Frances Chizoba

“…Climate change-induced shifts in temperature and precipitation patterns have disrupted rodent habitats, increasing human exposure to the virus. …”
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Evaluation of global distribution, genetic evolution, and mammalian infectivity and pathogenicity of H13 and H16 avian influenza viruses by Xiang Li1, Ao Li, Fengyi Qu, Yi Li, Fangyuan Chen, Xinru Lv, Qing An, Mengdan Fei, Hongyu Chen, Hongrui Liang, Xiaotian Zhang, Jinghao Li, Mingyuan Yu, Siyuan Qin, Linhong Xie, Shenglai Yin, Zheng Huang, Siyuan Yang, Heting Sun, Xiang Li2, Hongliang Chai

“…In summary, these findings indicate that host migration patterns are closely associated with the evolution of H13 and H16 AIVs. …”
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Dynamic changes in peripheral inflammation as a risk factor for perioperative sleep disturbances in elderly patients undergoing laparoscopic hepatobiliary surgery by Lai Wei, Lai Wei, Lai Wei, Xiaoyu Zhu, Yiming Zhao, Yi Zou, Tao Hu, Qian Huang, Jieqiong Li, Bingbing Pan, Bingbing Pan, Gaoyin Kong, Gaoyin Kong, Gaoyin Kong, Siyou Tan, Siyou Tan, Wenyan Chen, Wenyan Chen

“…The relationship between peripheral inflammatory status and PSD pathogenesis currently lacks substantial clinical evidence.ObjectiveThis study aims to evaluate the association between peripheral inflammation indicators and PSD in elderly patients undergoing laparoscopic hepatobiliary surgery, and to analyze the dynamic changes in peripheral inflammation in PSD patients throughout the perioperative period.Method and materialsUsing retrospective data, this study compares peripheral inflammatory markers (NLR, MLR, PLR, SII, IL-6, and IL-10) in patients with PSD vs. those with normal sleep patterns before and after surgery. Receiver operating characteristic (ROC) curves were employed to evaluate the discriminative power of these indicators for PSD. …”
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K27-linked RORγt ubiquitination by Nedd4 potentiates Th17-mediated autoimmunity by Qiuming Zeng, Hui Guo, Na Tang, Pranav S. Renavikar, Nitin J. Karandikar, Amy E. Lovett-Racke, Michael K. Racke, Chengkai Yan, Rong Tang, Sushmita Sinha, Krishnendu Ghosh, Jeremy P. Ryal, Song Ouyang, Min Chen, Foued Amari, Coppola Vincenzo, R. Marshall Pope, Yalan Li, Huan Yang, Wallace Y. Langdon, Jian Zhang

“…Nevertheless, the regulation of RORγt activation during Th17 cell differentiation by TCR signaling is yet to be elucidated. …”
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Tackling antimicrobial resistance in Bangladesh: A scoping review of policy and practice in human, animal and environment sectors. by Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam, Emily K Rousham, Bushra Zarin Islam, Shaikh Hassan

“…Nineteen articles on human health dealt with prescribing and/or use of antimicrobials, five on self-medication, two on non-compliance of dosage, and 10 on the sensitivity and resistance patterns of antibiotics. Four papers focused on the use of antimicrobials in food animals and seven on environmental contamination. …”
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Relevance of oncobiome in breast cancer evolution in an Argentine cohort by Leonardo Néstor Rubén Dandeu, Joel Lachovsky, Sofía Sidlik, Pablo Marenco, Daniela Orschanski, Pablo Aguilera, Martín Vázquez, María del Pilar Carballo, Elmer Fernández, Alberto Penas-Steinhardt, Norma Alejandra Chasseing, Vivian Labovsky

“…This finding is an indication that tumor cells are taking advantage of this effect of the microbiome during tumor progression. We conclude that oncobiome is dysbiotic in these patients, with distinct patterns in those with poor progression. …”
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Historical Overview of the Evolution of Multidrug-Resistant Gram-Negative Infections in Tunisia from 1999 to 2019 by Lamia Kanzari, Sana Ferjani, Basma Mnif, Faouzia Mahjoubi, Mariem Zribi, Khaoula Meftah, Asma Ferjani, Emna Mhiri, Yomna Ben Lamine, Yosr Kadri, Habiba Naija, Manel Hamdoun, Yosra Chebbi, Sarra Dhraief, Naglaa Mohamed, Hela Zaghden, Lamia Thabet, Wafa Achour, Olfa Bahri, Farouk Barguellil, Maha Mastouri, Sophia Besbes, Leila Slim, Hanen Smaoui, Adnene Hammami, Ilhem Boutiba-Ben Boubaker

“…<b>Background/Objectives</b>: As antimicrobial resistance patterns of Gram-negative bacteria change over time, this study aimed to analyze the antimicrobial susceptibility trends of <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i>, <i>Pseudomonas aeruginosa</i>, and <i>Acinetobacter baumannii</i> isolates in Tunisia. …”
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Impact assessment of differential chlormequat chloride exposure on soil fungal community dynamics by Qiujun Lin, Qiujun Lin, Xianxin Wu, Xianxin Wu, Lina Li, Lina Li, Tianshu Peng, Tianshu Peng, Xun Zou, Xun Zou, Guang Li, Guang Li, Jianzhong Wang, Jianzhong Wang, Chunjing Guo, Chunjing Guo

“…CC solutions were applied during critical growth phases (flowering and pod-setting stages). …”
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Association between accelerometer-measured physical activity and mortality in cancer survivors: A prospective cohort study from UK Biobank by Zhihan Jiang, Bingyan Wang, Yifei Zhao, Jing Weng, Jiaojiao Liao, Liyuan Tao, Kui Sun, Zhipeng Zhang, Xin Zhou, Wei Fu

“…HRs for cancer-specific mortality were 0.71 (95% CI, 0.58–0.88), 0.69 (95%CI, 0.55–0.87) and 0.61 (95%CI, 0.47–0.81) for the aforementioned groups. Similar patterns were observed for moderate-intensity physical activity but not for light-intensity physical activity. …”
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Patients with macroscopic lymph node metastasis expect poor prognosis after neoadjuvant chemotherapy in advanced ovarian cancer: a retrospective cohort study based on a single gyne... by Wen Guo, Jie Yin, Yu Gu, Yin Shan, Wei Wang, Yan Li, Meng Qin, Jiayu Chen, Ying Jin, Lingya Pan

“…Differences in terms of clinicopathological features, survival profiles, and recurrence patterns were analyzed between groups with different lymph node statuses. …”
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SOA Services Identification and Design Methods From Business Models: A Systematic Literature Review by Redouane Blal, Abderrahmane Leshob, Hafedh Mili, Imen Benzarti, Pierre Hadaya, Raqeebir Rab

“…We compared selected methods according to seven specific criteria, namely: design life cycle coverage, detailed specification support, SoaML support, service granularity, the use of patterns, automation, and tool support. The results confirm that SOA is an established architectural style for building effective ISs that support organizations&#x2019; business processes. …”
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Development and Assessment of a New Multichannel Electrocutaneous Device for Non-Invasive Somatosensory Stimulation for Magnetic Resonance Applications by Carolina Travassos, Alexandre Sayal, Paulo Fonte, Bruno Direito, Luis Lopes, Nuno Carolino, Sonia Afonso, Tania Lopes, Teresa Sousa, Miguel Castelo-Branco

“…Non-invasive electrocutaneous stimulation, which applies an electrical current flowing through the skin&#x2019;s surface to elicit a tactile percept, can be used in combination with functional magnetic resonance imaging (fMRI) to obtain somatotopic maps that illustrate the spatial patterns and functional organization of the primary somatosensory cortex (S1). …”
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