Multi‐omics profiling identifies TNFRSF18 as a novel marker of exhausted CD8⁺ T cells and reveals tumour‐immune dynamics in colorectal cancer by Tengfei Jia, Yingxi Guo, Xin meng Cheng, Zeyang Zhou, Xiaojiang Xu, Hebin Liu, Xiaodong Yang

“…Key points   Multi‐omics analysis reveals dynamic CD8+ T cell exhaustion patterns across CRC samples with different TNM stages. …”
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Biomechanical Changes and the Time Course of Recovery in Lower Extremities of Recreational Runners Following a Simulated Treadmill Half-Marathon by Wenjin Wang, Shulin Xu, Igor Komnik, Josef Viellehner, Marvin Zedler, Wolfgang Potthast

“…Previous research has demonstrated associations between running injuries and patterns of lower extremity biomechanics, as well as indicating that inadequate rest between training sessions can result in injuries and underperformance. …”
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Mechanisms behind grouting pressure jumping in low-permeability limestones and techniques for grouting pressure control by Zhenli FAN, Lutong CAO, Yong CUI, Zhiwei ZHANG, Fengda ZHANG

“…In this context, issues including the confined water hazards in the floor and karst water preservation become increasingly pronounced. During the advanced surface treatment of karst water hazards in coal seam floors, the unclear patterns of matching between grout selection and grouting pressure control lead to empirical parameter selection, thereby yielding poor performance of grouting reinforcement. …”
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Sociodemographic Differences in Logins and Engagement With the Electronic Health Coach Messaging Feature of a Mobile App to Support Opioid and Stimulant Use Recovery: Results From... by Lindsey M Filiatreau, Hannah Szlyk, Alex T Ramsey, Erin Kasson, Xiao Li, Zhuoran Zhang, Patricia Cavazos-Rehg

“…However, data on uptake and engagement with specific app features (eg, in-app messaging) are often lacking, limiting our ability to understand nuanced patterns of app use. ObjectiveThis study aims to characterize sociodemographic differences in uptake and engagement with a smartphone app (uMAT-R) to support recovery efforts in a sample of individuals with opioid and stimulant use disorders in the Greater St. …”
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Assessment of Water Resources Carrying Capacity and Analysis of Its Coupling Coordination in the Yangtze River Economic Belt by XIONG Ying, JIANG Yi-xin, CHEN Si-xuan

“…Spatially, the center of water resources carrying capacity shifted southwestward toward areas with relatively lower capacity, which may be related to regional economic development patterns, industrial restructuring, and differences in water use efficiency. …”
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Transcriptomic Profiling Reveals Altered Expression of Genes Involved in Metabolic and Immune Processes in NDV-Infected Chicken Embryos by Malarmathi Muthusamy, Kannaki T. Ramasamy, Sunday Olusola Peters, Srinivasan Palani, Vasudevan Gowthaman, Murali Nagarajan, Sivakumar Karuppusamy, Vasanthakumar Thangavelu, Thiruvenkadan Aranganoor Kannan

“…Key metabolic genes, such as ALDOB (3.27 logFC), PRPS2 (2.66 logFC), and XDH (2.15 logFC), exhibited altered expression patterns, while DCK2 (−1.99 logFC) and TK1 (−2.11 logFC) were also affected. …”
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Integrated commercial and low-fishmeal fermented feed boosts survival and modulates intestinal microbiota in pacific white shrimp (Litopenaeus vannamei) by Yanbo Cheng, Lanfen Fan, Yifei Liu, Kuiying Su, Guohuan Xu

“…The gut microbiota of shrimp on two feeding diets showed distinct patterns in the predicted pathways related to immune and infectious disease, with diets also affecting their phenotypic traits. …”
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Spatial yield gains in empty-row optimized rice–crab co-culture are linked to nifH-driven nitrogen compensation in border rows by Tiexin Yang, Dandan Jin, Liqiang Dong, Liang Ma, Zhengyan Pan, Zhiqiang Li, Fuyu Sun, Xiaosen Sun, Lei Yu

“…Plots were arranged in CK and ERC-12 patterns; the latter was spatially divided into boundary (PB), intermediate (PM), and central (PC) zones. …”
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Multiple modes of shoreline change along the Alaskan Beaufort Sea observed using ICESat-2 altimetry and satellite imagery by M. B. Bryant, A. A. Borsa, E. J. Anderson, E. J. Anderson, C. C. Masteller, R. J. Michaelides, M. R. Siegfried, M. R. Siegfried, A. P. Young

“…Our topographic profiles from ICESat-2 sample three distinct shoreline types (a bluff, a small drained lake basin, and a dune in front of a large drained lake basin) that exhibit different patterns of shoreline change (in terms of both position and morphology) over the 3-year study period. …”
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ECOLOGICAL AND PHYTOCENOTIC STRUCTURE OF VEGETATION COVER OF INTERFLUVE OF RIVERS RUSSKAYA AND VERBOVKA (STAVROPOL PLATEAU) by V. N. Belous, N. G. Lihovid, M. J. Kuharuk, A. A. Lihovid

“…In the course of field surveys, ecologicalphytocenotic features and distribution patterns of individual elements of the forest-steppe complex of the rivers Russkaya and Verbovka interfluve were established, which are primarily associated with the nature of the soil cover, the temperature regime and the water-physical properties of local soils. …”
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THE INFLAMMASOME DRIVES MICROVASCULAR IMPAIRMENT IN MOUSE MODELS OF INTRAVASCULAR HEMOLYSIS by PL Brito, EMFG Azevedo, LFS Gushiken, FC Leonardo, FF Costa, N Conran

“…Introduction: Intravascular hemolysis (IVH) results in the release of damage-associated molecular patterns (DAMPs) into the circulation, particularly hemoglobin (Hb) and heme, which can trigger NLRP3 inflammasome activation and a sterile inflammatory response. …”
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Creatividad y emergencia espontánea de habilidades de danza (Creativity and dance skills emergency) by Carlota Torrents Martín, Robert Hristovsk, Natàlia Balagué i Serre

“…Nevertheless, few sport researchers have studied the creative behavior emergence by means of the complex systems capacity to self-organize in complex patterns. Using the example of Contact improvisation, the aim of this paper is to show how creativity emerges during the improvisation following non linear dynamical principles. …”
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Viral etiology of severe acute respiratory infections in hospitalized patients, Shandong, China. by Chunwang Li, Yujie He, Xiao Pan, Huimin Yin, Yaowen Pei, Shaoxia Song, Lin Sun, Shu Zhang, Julong Wu, Zhong Li, Xianjun Wang, Zengqiang Kou, Lei Zhao, Weijia Xing, Ti Liu

“…<h4>Background</h4>Severe Acute Respiratory Infection (SARI) represents a critical global public health challenge, accounting for substantial severe morbidity and hospitalization burdens with distinct geographical patterns in etiological profiles. This study systematically characterizes the epidemiological and clinical phenotypes of SARI patients in Shouguang county, Shandong Province, China.…”
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Age-Related Changes in Action Observation EEG Response and Its Effect on BCI Performance by Fukang Zeng, Xingyu Wen, Hongmei Tang, Guiyu Hu, Wensheng Hou, Xin Zhang

“…Age-dependent EEG responses emerged across multiple dimensions: 1) Prefrontal ApEn, SamEn, and RPR exhibited distinct aging patterns; 2) Brain network analysis uncovered significant intergroup differences in <inline-formula> <tex-math notation="LaTeX">$\alpha $ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula> band connectivity strength; 3) <inline-formula> <tex-math notation="LaTeX">$\theta $ </tex-math></inline-formula> band network topology demonstrated reduced prefrontal nodal degree along with enhanced global efficiency in older subjects. …”
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Parenthood stressfulness and intensity in the students’ views by I. V. Tikhonova, Yu. V. Misiyuk, U. Yu. Sevastyanova

“…The research outcomes contribute to the understanding of the patterns and factors of the formation of ideas about the stress of parenthood, its role in the reproductive plans of students. …”
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Diet-gut microbiome interaction and its impact on host blood glucose homeostasis: a series of nutritional n-of-1 trialsResearch in context by Yuanqing Fu, Wanglong Gou, Haili Zhong, Yunyi Tian, Hui Zhao, Xinxiu Liang, Menglei Shuai, Lai-Bao Zhuo, Zengliang Jiang, Jun Tang, Jose M. Ordovas, Yu-ming Chen, Ju-Sheng Zheng

“…Findings: We demonstrated that the gut microbiome exhibited both intra-individually dynamic and inter-individually personalized signatures during the interventions. At the single-subject resolution, we observed person-specific response patterns of gut microbiota to interventional diets. …”
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COVID-19 vaccine evidence monitoring assisted by artificial Intelligence: An emergency system implemented by the Public Health Agency of Canada to capture and describe the trajecto... by Su Hyun Lim, Mona Hersi, Ramya Krishnan, Joshua Montroy, Bonnie Rook, Kelly Farrah, Yung-En Chung, Adrienne Stevens, Joseline Zafack, Eva Wong, Nicole Forbes, April Killikelly, Kelsey Young, Matthew Tunis

“…Analysis of COVID-19 vaccine research patterns supports projections of research volume, type, and rate that will help predict resourcing and information needs to plan future emergency vaccine guidance activities.…”
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The GRAS gene family and its roles in pineapple (Ananas comosus L.) developmental regulation and cold tolerance by Jinting Lin, Jiahao Wu, Dan Zhang, Xinkai Cai, Lumiao Du, Lin Lu, Chaojia Liu, Shengzhen Chen, Qinglong Yao, Shiyu Xie, Xiaowen Xu, Xiaomei Wang, Ruoyu Liu, Yuan Qin, Ping Zheng

“…In contrast, no consistent expression patterns were observed among genes in other subfamilies, suggesting that various regulatory factors, such as miRNAs, transcription factors, and cis-regulatory elements, may contribute to the diverse functions of AcGRAS members, even within the same subfamily. …”
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Decoding Cellular Landscapes: Unravelling Periodontitis and Periapical Periodontitis at the Single-Cell Frontier by Yuan Li, Jun Wang, Yu Zhang, Dengke Li, Wuyang Zhang, Xuebing Li, Bolun Zhang, Kaijin Hu, Jianfei Yan, Yang Xue

“…The key genes were highly expressed during early T cell and macrophage differentiation and during late fibroblast and plasma cell differentiation. …”
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SEM observation of pollen in 17 cherry germplasm resources by ZHOU Junman, DUAN Xuwei, ZHANG Kaichun, ZHANG Xiaoming, YAN Guohua, ZHOU Yu, WANG Jing, FENG Chen, WANG Wei, WANG Naiyu, YUAN Hui, WU Chuanbao

“…These germination grooves extended to both ends of the pollen, but no joint grooves were formed in the polar region. The outer wall pattern was striped, and there were obvious differences in stripe width, spacing, slope, clarity, and outer wall hole density among different germplasm resources. …”
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