Genome-wide identification and characterization of MdCYP86A family in apple by Hui-Min Lv, Rui-Han Qi, Zi-Han Yu, Yao-Yang Man, Yan-Hui Lv, Han Jiang, Tao Wang, Ya-Li Zhang, Yuan-Yuan Li

“…The tissue-specific expression patterns revealed that the highest expression tissue was in flower by real-time quantitative reverse transcription (RT-qPCR). …”
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Proteolysis and volatile compounds in Mediterranean buffalo milk blue cheese: Quality determinants and functional peptides by Federica Della Cerra, Giuseppina Garro, Rosaria Cozzolino, Sabrina De Pascale, Mariapia Esposito, Gianluca Picariello, Simonetta Caira, Andrea Scaloni, Francesca Marino, Francesco Addeo

“…Casein phosphopeptides displayed ripening-dependent dephosphorylation patterns, driven by fungal phosphatase activity. VOC profiling revealed 55 key compounds, mainly methyl ketones, esters, and short-chain acids, that contributed to the evolving sensory profile of the cheese.These findings highlight the complex biochemical transformations that define both the functional and sensory qualities of buffalo blue cheese. …”
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Association of gut microbiota and immune gene expression with response to targeted therapy in BRAF mutated melanoma by Mora Guardamagna, Miguel-Angel Berciano-Guerrero, Rocío Lavado-Valenzuela, Édouard Auclin, Juan Luis Onieva-Zafra, Isaac Plaza-Andrades, Javier Oliver, Alicia Garrido-Aranda, Elisabeth Perez-Ruiz, Martina Álvarez, María Carmen Ocaña, María Isabel Queipo-Ortuño, Isabel Barragán, Antonio Rueda-Dominguez

“…Our findings suggest that specific gut microbial taxa and immune-related gene expression patterns may be associated with differential responses to BRAF/MEK-targeted therapy in metastatic melanoma.…”
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Diversity of Gracilariaceae (Gracilariales, Rhodophyta) Across Distinct Ecosystems in Zhanjiang, China: A Foundation for Screening Potential Cultivable Species in Southern China by Zhaojun Zeng, Enyi Xie, Huaqiang Tan, Xuefeng Wang, Wencheng Yang, Nenghui Li, Qun Lai, Kun Lin, Manning Lei, Xinlu Wu, Jianjun Cui

“…The diversity and seasonal and spatial distribution patterns of Gracilariaceae species in different ecosystems were systematically analyzed, and taxonomic studies were performed on species with disputed taxonomic identities using morphological and multi‐gene marker techniques to clarify their classification status. …”
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Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study by Esat Kivanc Kaya, Burcin Halacli, Goksel Guven, Mehmet Yildirim, Asir Eren Seven, Emin Gemcioglu, Meltem Simsek, Begum Erdemir Sullu, Recep Civan Yuksel, Ahmet Safa Kaynar, Aliye Esmaoglu, Banu Kilicaslan, Seda Banu Akinci, Kursat Gundogan, Ebru Ortac Ersoy, Jordi Rello, Arzu Topeli, On behalf of the Turkish Intensive Care Studies-Network (TRICS-Net)

“…The main aim of this study was to assess clinical infections and microbiological features in patients admitted to the ICU following the 2023 earthquake in the southeastern region of Türkiye with a focus on the timing of culture positivity during their ICU stay. The secondary objectives included determining antibiotic susceptibility patterns, identifying the types of antibiotics administered upon ICU admission, evaluating the appropriateness of antibiotic usage, assessing patient outcomes, and identifying factors that influence microbiologically confirmed clinical infections. …”
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Large and persistent subnational inequalities in reproductive, maternal, newborn and child health intervention coverage in sub-Saharan Africa by Inácio Crochemore Mohnsam da Silva, Aluísio J D Barros, Ties Boerma, Fernando C Wehrmeister, Leonardo Zanini Ferreira, Ahmad Reza Hosseinpoor, Liliana Carvajal-Aguirre, Abdoulaye Maïga, Safia S Jiwani, Tyler Andrew Porth, Chelsea Maria Taylor, Dessalegn Y Melesse, Kathleen L Strong, Cheikh Mbacké Faye, Martin Kavao Kavao Mutua, Estelle Monique Sidze, Tome Ca, Richard Kumapley

“…The analyses show the wide range of subnational inequality patterns such as low overall national coverage with very large top inequality involving the capital city, intermediate national coverage with bottom inequality in disadvantaged regions, and high coverage in all regions with little inequality. …”
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Porto Alegre Line predicts lenticulostriate arteries encasement and extent of resection in insular gliomas. A preliminary study by Gustavo Rassier Isolan, Gustavo Rassier Isolan, Gustavo Rassier Isolan, Samir Ale Bark, Samir Ale Bark, Jander Moreira Monteiro, Jander Moreira Monteiro, Tobias A. Mattei, Kaan Yağmurlu, Rafaela Fernandes Gonçalves, Rafaela Fernandes Gonçalves, Osvaldo Malafaia, Rafael Roesler, Rafael Roesler, Rafael Roesler, Jurandir Marcondes Ribas Filho

“…In cases with no tumor located medial to Porto Alegre line, our medial resection limit, mainly for the tumor part located next to the limen insula, was the inferior fronto-occipital fasciculus (IFOF), identified through altered speech patterns during electric subcortical stimulation. In cases with no assumed LSTa involvement, the parameter used to stop resection was the confirmation of the corticospinal tract with 10-mA stimulus. …”
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Real-time intestinal perfusion assessment for anastomotic site selection using laser speckle contrast imaging: Verification in a porcine model by Danique J.I. Heuvelings, Mahdi Al-Taher, Joost Calon, Manish Chand, Laurents P.S. Stassen, Tim Lubbers, Kevin P. Wevers, Luigi Boni, Nicole D. Bouvy, Wido Heeman

“…The questionnaire revealed that the senior surgeons were satisfied with the perfusion imager, particularly in terms of minimal latency, ease of use and set up, and ability to accurately represent blood flow patterns as these questions showed a (very) strong agreement in 80 %. …”
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User engagement in a digital health intervention designed for young people who have experienced technology-assisted sexual abuse (i-Minds trial) by Sandra Bucci, Xiaolong Zhang, Kaja Dabrowska, Amanda Larkin, Ethel Quayle, Matthias Schwannauer, Filippo Varese, Pauline Whelan

“…Our objective is to describe engagement patterns for YP people who used the i-Minds app. Methods: The i-Minds app is a co-designed mentalisation-based DHI for YP who have experienced TASA. …”
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Rift Valley Fever outbreaks in the East African Community: insights from ProMed data (2010–2024) by Pacifique Ndishimye, Pacifique Ndishimye, Pacifique Ndishimye, Therese Umuhoza, Therese Umuhoza, Therese Umuhoza, Brigitte Umutoni, Brigitte Umutoni, Fathiah Zakham, Fathiah Zakham, Matin Ndayambaje, Matin Ndayambaje, Benjamin Hewins, Methode Ngabo Gasana, Ali Toloue Ostadgavahi, Gustavo Sganzerla, Fabrice Ndayisenga, David Kelvin, Jean Claude Udahemuka, Jean Claude Udahemuka, Jean Claude Udahemuka

“…This study seeks to analyze the spatial and temporal distribution and trends of RVF outbreaks within the East African Community (EAC) countries, offering insights into the patterns and progression of these outbreaks in the region.MethodsWe conducted a retrospective analysis of the Program for Monitoring Emerging Diseases (ProMed), a digital, event-based disease surveillance system, to identify reports of outbreak events in Uganda, Kenya, Rwanda, Burundi, Tanzania, and South Sudan from 2010 to 2024. …”
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Affective neural signatures do not distinguish women with emotion dysregulation from healthy controls: A mega-analysis across three task-based fMRI studies by M. Sicorello, J. Herzog, T.D. Wager, G. Ende, M. Müller-Engelmann, S.C. Herpertz, M. Bohus, C. Schmahl, C. Paret, I. Niedtfeld

“…Neural signatures—i.e. multivariate brain-patterns trained to be both sensitive and specific to a construct of interest—might alleviate this problem, but are rarely applied to mental disorders. …”
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Effect of <i>Caragana korshinskii</i> Plantation Succession on Community Stability in Alpine Sandy Regions by Zhengchen Shi, Li Ma, Zhonghua Zhang, Honglin Li, Dengxian Wei, Xuebin Zhao, Ruimin Qin, Hongye Su, Shan Li, Xue Hu, Haze Ade, Huakun Zhou

“…The findings will clarify the stability evolution patterns of <i>Caragana korshinskii</i> plantation during desertification control and contribute to promoting green development strategies. …”
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Uncovering the breeding contribution of transposable elements from landraces to improved varieties through pan-genome-wide analysis in rice by Xiaoxia Li, Xiaoxia Li, Xiaofan Dai, Xiaofan Dai, Huiying He, Wu Chen, Qian Qian, Qian Qian, Lianguang Shang, Lianguang Shang, Longbiao Guo, Wenchuang He

“…Combining with haplotype analysis, we demonstrated potential patterns of how TEs affect gene expression variation and thereby participate in the improvement of important agronomic traits in rice.DiscussionCollectively, our results highlight the contributions of TE variations to rice improvement in shaping the genetic basis of modern rice varieties and will facilitate the exploration of superior genes and advance molecular breeding efforts in rice.…”
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Molecular Characterization of Clinical Isolates of Methicillin-Resistant <i>Staphylococcus aureus</i> from Chonburi, Thailand by Patcharawalai Wassanarungroj, Panida Nobthai, Sirigade Ruekit, Apichai Srijan, Prawet Sukhchat, Oralak Serichantalergs, John M. Crawford, Brett E. Swierczewski, Sidhartha Chaudhury, Paphavee Lertsethtakarn

“…Overall, our findings reveal that the <i>S. aureus</i> isolates in this study differ from previous reports in Thailand, indicating a potential shift in local strains, highlighting the need for ongoing molecular surveillance of multidrug resistance patterns of MRSA in Southeast Asia.…”
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Development of a Wearable Sleeve-Based System Combining Polymer Optical Fiber Sensors and an LSTM Network for Estimating Knee Kinematics by B. L. Pugliese, A. Angelucci, F. Parisi, S. Sapienza, E. Fabara, G. Corniani, A. S. Tenforde, A. Aliverti, D. Demarchi, P. Bonato

“…This study presents a novel wearable solution integrating Polymer Optical Fiber (POF) sensors into a knee sleeve to monitor knee flexion/extension (F/E) patterns during walking. POF sensors offer advantages such as flexibility, light weight, and robustness to electromagnetic interference, making them ideal for wearable applications. …”
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Simulating the drought response of European tree species with the dynamic vegetation model LPJ-GUESS (v4.1, 97c552c5) by B. F. Meyer, J. P. Darela-Filho, K. Gregor, A. Buras, Q.-L. Gu, A. Krause, D. Liu, P. Papastefanou, S. Asuk, T. E. E. Grams, C. S. Zang, A. Rammig

“…Our results indicate that the new model is able to capture drought-induced patterns of evapotranspiration along an isohydric gradient and manages to reproduce flux observations during drought better than standard LPJ-GUESS does. …”
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Bright Dots and Coronal Plume Formation in Sunspot Penumbra by Ayla Weitz, Sanjiv K. Tiwari, Gianna Cauzzi, Kevin P. Reardon, Bart De Pontieu

“…Space-time maps along the plume axis show parabolic and V-shaped patterns, and we conclude that some of these dots are possible signatures of magneto-acoustic shocks. …”
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Trends in Positive Urine Culture Rates and Antimicrobial Resistance in Non-Hospitalized Children from Western Romania: A Retrospective Observational Study by Constantin Catalin Marc, Maria Daniela Mot, Monica Licker, Delia Muntean, Daniela Teodora Marti, Ana Alexandra Ardelean, Alina Ciceu, Sergiu Adrian Sprintar, Daniela Adriana Oatis, Alin Gabriel Mihu, Tudor Rares Olariu

“…Future studies should focus on different regions and regularly update resistance patterns to keep treatment and prevention strategies aligned with local conditions.…”
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Preoperative short-term fasting in paediatric cancer care is safe, feasible and activates protective responses by D.S.J. Komninos, C.A.J. Oudmaijer, R.A. Ozinga, K. Smit, J.N.M. Ijzermans, J.H.J. Hoeijmakers, R.C. Minnee, M.M. van den Heuvel-Eibrink, W.P. Vermeij

“…Questionnaires demonstrated that patients and parents experienced no obvious burden and described the intervention as highly feasible. RNA-expression patterns in normal kidney tissue unveiled distinctions between cases with STF and those without, displaying significant difference in relevant pathways linked to activated protective-responses, resembling those in adults. …”
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Advanced 4-chamber echocardiography techniques enable clinically matched precise characterization of heart disease progression in mice by Ege Kacira, Mariam F. Oueis, Nawal H. Tamimi, Sarah L. Sturgill, Xianyao Xu, Thomas J. Hund, Mark T. Ziolo, Yuchi Han, Isabelle Deschênes, Ji-dong Fu

“…Importantly, A4CLAX further enables clinically relevant Doppler assessments, allowing detection of mitral valve regurgitation, restrictive filling patterns, and desynchronized valve motion. It also facilitates right ventricle (RV) functional evaluation and improved atrial visualization, revealing progressive enlargement of the left atrial (LA) and left atrial appendage (LAA) associated with worsening diastolic function. …”
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